{"id":"https://openalex.org/W2090776058","doi":"https://doi.org/10.1016/0268-9499(89)90139-2","title":"Increased expression of U-plasminogen activator is correlated with oncogene-induced transformation of human fibroblasts to malignancy","display_name":"Increased expression of U-plasminogen activator is correlated with oncogene-induced transformation of human fibroblasts to malignancy","publication_year":1989,"publication_date":"1989-01-01","ids":{"openalex":"https://openalex.org/W2090776058","doi":"https://doi.org/10.1016/0268-9499(89)90139-2","mag":"2090776058"},"language":"en","primary_location":{"id":"doi:10.1016/0268-9499(89)90139-2","doi":"https://doi.org/10.1016/0268-9499(89)90139-2","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0268-9499(89)90139-2","pdf_url":null,"source":{"id":"https://openalex.org/S4210174420","display_name":"Fibrinolysis and Proteolysis","issn_l":"0268-9499","issn":["0268-9499","1369-0191","1532-222X","2213-9761"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310321208","host_organization_name":"Churchill Livingstone","host_organization_lineage":["https://openalex.org/P4310321208","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Churchill Livingstone","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Fibrinolysis","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079636370","display_name":"Jerzy Jankun","orcid":"https://orcid.org/0000-0003-2354-4046","observed_orcids":["https://orcid.org/0000-0003-2354-4046"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jerzy Jankun","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064971295","display_name":"Lonnie D. Milam","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lonnie D. Milam","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103678812","display_name":"Veronica M. Maher","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Veronica M. Maher","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5003625150","display_name":"J. Justin McCormick","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J.Justin McCormick","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.14485981,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"3","issue":null,"first_page":"25","last_page":"26"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11501","display_name":"TGF-\u03b2 signaling in diseases","score":0.010200000368058681,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.0027000000700354576,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oncogene-induced-transformation","display_name":"oncogene-induced transformation","score":0.8180000185966492},{"id":"https://openalex.org/keywords/human-fibroblasts","display_name":"human fibroblasts","score":0.9020000100135803},{"id":"https://openalex.org/keywords/malignant-transformation","display_name":"malignant transformation","score":0.7900000214576721},{"id":"https://openalex.org/keywords/plasminogen-activator","display_name":"plasminogen activator","score":0.7099999785423279}],"concepts":[{"id":"https://openalex.org/C2781018059","wikidata":"https://www.wikidata.org/wiki/Q207609","display_name":"Oncogene","level":4,"score":0.7410930395126343},{"id":"https://openalex.org/C2779399171","wikidata":"https://www.wikidata.org/wiki/Q1483951","display_name":"Malignancy","level":2,"score":0.6385005116462708},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.6262723803520203},{"id":"https://openalex.org/C2779679481","wikidata":"https://www.wikidata.org/wiki/Q13581432","display_name":"Plasminogen activator","level":2,"score":0.5712130665779114},{"id":"https://openalex.org/C31033888","wikidata":"https://www.wikidata.org/wiki/Q752076","display_name":"Malignant transformation","level":2,"score":0.5568203926086426},{"id":"https://openalex.org/C204241405","wikidata":"https://www.wikidata.org/wiki/Q461499","display_name":"Transformation (genetics)","level":3,"score":0.48777204751968384},{"id":"https://openalex.org/C88045685","wikidata":"https://www.wikidata.org/wiki/Q174576","display_name":"Activator (genetics)","level":3,"score":0.48698076605796814},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.39745140075683594},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3668927550315857},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.35416799783706665},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.32131505012512207},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.23757663369178772},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.18265321850776672},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1798340380191803},{"id":"https://openalex.org/C29537977","wikidata":"https://www.wikidata.org/wiki/Q188941","display_name":"Cell cycle","level":3,"score":0.13037046790122986}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/0268-9499(89)90139-2","doi":"https://doi.org/10.1016/0268-9499(89)90139-2","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0268-9499(89)90139-2","pdf_url":null,"source":{"id":"https://openalex.org/S4210174420","display_name":"Fibrinolysis and Proteolysis","issn_l":"0268-9499","issn":["0268-9499","1369-0191","1532-222X","2213-9761"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310321208","host_organization_name":"Churchill Livingstone","host_organization_lineage":["https://openalex.org/P4310321208","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Churchill Livingstone","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Fibrinolysis","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8999999761581421,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2165615285","https://openalex.org/W2015466426","https://openalex.org/W2068515595","https://openalex.org/W7097847038","https://openalex.org/W2069782319","https://openalex.org/W1982221552","https://openalex.org/W4230096087","https://openalex.org/W2437816248","https://openalex.org/W2068999933","https://openalex.org/W2069535552"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-07-28T07:46:37.118299","created_date":"2016-06-24T00:00:00"}