{"id":"https://openalex.org/W2090770751","doi":"https://doi.org/10.1055/s-1979-28592","title":"2,2,2-Tribromoethyl 2-Chloro-4-t-butylphenyl Phosphorochloridate: A Convenient Phosphorylating Agent for the Synthesis of DNA-Fragments by the Phosphotriester Approach","display_name":"2,2,2-Tribromoethyl 2-Chloro-4-t-butylphenyl Phosphorochloridate: A Convenient Phosphorylating Agent for the Synthesis of DNA-Fragments by the Phosphotriester Approach","publication_year":1979,"publication_date":"1979-01-01","ids":{"openalex":"https://openalex.org/W2090770751","doi":"https://doi.org/10.1055/s-1979-28592","mag":"2090770751"},"language":"en","primary_location":{"id":"doi:10.1055/s-1979-28592","doi":"https://doi.org/10.1055/s-1979-28592","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-1979-28592","pdf_url":null,"source":{"id":"https://openalex.org/S197964166","display_name":"Synthesis","issn_l":"0039-7881","issn":["0039-7881","1437-210X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Synthesis","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112159255","display_name":"Ren\ufffd Arentzen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121797337","display_name":"Leiden University","ror":"https://ror.org/027bh9e22","country_code":"NL","type":"education","lineage":["https://openalex.org/I121797337"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"R. Arentzen","raw_affiliation_strings":["Department of Organic Chemistry, Gorlaeus Laboratories, State University of Leiden,  P.O. Box 9502, 2300 RA, Leiden, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Organic Chemistry, Gorlaeus Laboratories, State University of Leiden,  P.O. Box 9502, 2300 RA, Leiden, The Netherlands","institution_ids":["https://openalex.org/I121797337"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057477527","display_name":"Constant A. A. van Boeckel","orcid":"https://orcid.org/0000-0002-1576-9598","observed_orcids":["https://orcid.org/0000-0002-1576-9598"]},"institutions":[{"id":"https://openalex.org/I121797337","display_name":"Leiden University","ror":"https://ror.org/027bh9e22","country_code":"NL","type":"education","lineage":["https://openalex.org/I121797337"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"C. A. A. Van Boeckel","raw_affiliation_strings":["Department of Organic Chemistry, Gorlaeus Laboratories, State University of Leiden,  P.O. Box 9502, 2300 RA, Leiden, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Organic Chemistry, Gorlaeus Laboratories, State University of Leiden,  P.O. Box 9502, 2300 RA, Leiden, The Netherlands","institution_ids":["https://openalex.org/I121797337"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113565600","display_name":"G. van der Marel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121797337","display_name":"Leiden University","ror":"https://ror.org/027bh9e22","country_code":"NL","type":"education","lineage":["https://openalex.org/I121797337"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"G. Van Der Marel","raw_affiliation_strings":["Department of Organic Chemistry, Gorlaeus Laboratories, State University of Leiden,  P.O. Box 9502, 2300 RA, Leiden, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Organic Chemistry, Gorlaeus Laboratories, State University of Leiden,  P.O. Box 9502, 2300 RA, Leiden, The Netherlands","institution_ids":["https://openalex.org/I121797337"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108217170","display_name":"Jacques H. VAN BOOM","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121797337","display_name":"Leiden University","ror":"https://ror.org/027bh9e22","country_code":"NL","type":"education","lineage":["https://openalex.org/I121797337"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"J. H. Van Boom","raw_affiliation_strings":["Department of Organic Chemistry, Gorlaeus Laboratories, State University of Leiden,  P.O. Box 9502, 2300 RA, Leiden, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Organic Chemistry, Gorlaeus Laboratories, State University of Leiden,  P.O. Box 9502, 2300 RA, Leiden, The Netherlands","institution_ids":["https://openalex.org/I121797337"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I121797337"],"apc_list":null,"apc_paid":null,"fwci":9.6571,"has_fulltext":false,"cited_by_count":37,"citation_normalized_percentile":{"value":0.99355666,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"1979","issue":"02","first_page":"137","last_page":"139"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11748","display_name":"Organophosphorus compounds synthesis","score":0.9672999978065491,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11748","display_name":"Organophosphorus compounds synthesis","score":0.9672999978065491,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.023800000548362732,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13239","display_name":"Phosphorus compounds and reactions","score":0.003000000026077032,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/phosphorylating-agents","display_name":"phosphorylating agents","score":0.8040000200271606},{"id":"https://openalex.org/keywords/phosphotriester-approach","display_name":"phosphotriester approach","score":0.8169999718666077},{"id":"https://openalex.org/keywords/phosphoramidite","display_name":"phosphoramidite","score":0.5759999752044678},{"id":"https://openalex.org/keywords/oligonucleotide-synthesis","display_name":"oligonucleotide synthesis","score":0.699999988079071}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9707063436508179},{"id":"https://openalex.org/C11960822","wikidata":"https://www.wikidata.org/wiki/Q242736","display_name":"Phosphorylation","level":2,"score":0.6345539093017578},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.6105514168739319},{"id":"https://openalex.org/C64241487","wikidata":"https://www.wikidata.org/wiki/Q5205774","display_name":"DNA synthesis","level":3,"score":0.4631950259208679},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.4538919925689697},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.4203253984451294},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2437257468700409}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1055/s-1979-28592","doi":"https://doi.org/10.1055/s-1979-28592","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-1979-28592","pdf_url":null,"source":{"id":"https://openalex.org/S197964166","display_name":"Synthesis","issn_l":"0039-7881","issn":["0039-7881","1437-210X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Synthesis","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2056478476","https://openalex.org/W4240331057","https://openalex.org/W2011953976","https://openalex.org/W2053728859","https://openalex.org/W2102010812","https://openalex.org/W4242980080","https://openalex.org/W2029498531","https://openalex.org/W1964794683","https://openalex.org/W2950912661","https://openalex.org/W2950692412"],"abstract_inverted_index":null,"counts_by_year":[{"year":2013,"cited_by_count":1}],"updated_date":"2026-09-27T08:07:27.782135","created_date":"2016-06-24T00:00:00"}