{"id":"https://openalex.org/W2090739153","doi":"https://doi.org/10.1038/nrgastro.2010.21","title":"Pathology of nonalcoholic fatty liver disease","display_name":"Pathology of nonalcoholic fatty liver disease","publication_year":2010,"publication_date":"2010-03-02","ids":{"openalex":"https://openalex.org/W2090739153","doi":"https://doi.org/10.1038/nrgastro.2010.21","mag":"2090739153","pmid":"https://pubmed.ncbi.nlm.nih.gov/20195271"},"language":"en","primary_location":{"id":"doi:10.1038/nrgastro.2010.21","doi":"https://doi.org/10.1038/nrgastro.2010.21","is_oa":false,"landing_page_url":"https://doi.org/10.1038/nrgastro.2010.21","pdf_url":null,"source":{"id":"https://openalex.org/S120397320","display_name":"Nature Reviews Gastroenterology & Hepatology","issn_l":"1759-5045","issn":["1759-5045","1759-5053"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Reviews Gastroenterology &amp; Hepatology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072014736","display_name":"Elizabeth M. Brunt","orcid":"https://orcid.org/0000-0003-1862-325X","observed_orcids":["https://orcid.org/0000-0003-1862-325X"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Elizabeth M. Brunt","raw_affiliation_strings":["Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA. ebrunt@path.wustl.edu","Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA. ebrunt@path.wustl.edu","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA","institution_ids":["https://openalex.org/I204465549"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5072014736"],"corresponding_institution_ids":["https://openalex.org/I204465549"],"apc_list":null,"apc_paid":null,"fwci":4.2797,"has_fulltext":false,"cited_by_count":486,"citation_normalized_percentile":{"value":0.96704871,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"7","issue":"4","first_page":"195","last_page":"203"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11834","display_name":"Liver Diseases and Immunity","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/non-alcoholic-fatty-liver-disease","display_name":"non-alcoholic fatty liver disease","score":1.0},{"id":"https://openalex.org/keywords/histopathology","display_name":"histopathology","score":0.7120000123977661},{"id":"https://openalex.org/keywords/steatosis","display_name":"steatosis","score":0.7789999842643738},{"id":"https://openalex.org/keywords/steatohepatitis","display_name":"steatohepatitis","score":0.9649999737739563},{"id":"https://openalex.org/keywords/liver-biopsy","display_name":"liver biopsy","score":0.8870000243186951},{"id":"https://openalex.org/keywords/liver-fibrosis","display_name":"liver fibrosis","score":0.8600000143051147},{"id":"https://openalex.org/keywords/pediatric-nafld","display_name":"pediatric NAFLD","score":0.8500000238418579},{"id":"https://openalex.org/keywords/metabolic-syndrome","display_name":"metabolic syndrome","score":0.7860000133514404},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.9599999785423279},{"id":"https://openalex.org/keywords/hepatocellular-carcinoma","display_name":"hepatocellular carcinoma","score":0.8560000061988831},{"id":"https://openalex.org/keywords/cardiovascular-risk","display_name":"cardiovascular risk","score":0.9319999814033508},{"id":"https://openalex.org/keywords/liver-imaging","display_name":"liver imaging","score":0.40700000524520874}],"concepts":[{"id":"https://openalex.org/C2776954865","wikidata":"https://www.wikidata.org/wiki/Q1546498","display_name":"Nonalcoholic fatty liver disease","level":4,"score":0.8702296018600464},{"id":"https://openalex.org/C2776175330","wikidata":"https://www.wikidata.org/wiki/Q1365091","display_name":"Steatosis","level":2,"score":0.840297281742096},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8341927528381348},{"id":"https://openalex.org/C2779478299","wikidata":"https://www.wikidata.org/wiki/Q2335423","display_name":"Steatohepatitis","level":4,"score":0.655773401260376},{"id":"https://openalex.org/C2777766500","wikidata":"https://www.wikidata.org/wiki/Q360841","display_name":"Liver biopsy","level":3,"score":0.646050751209259},{"id":"https://openalex.org/C2780559512","wikidata":"https://www.wikidata.org/wiki/Q605709","display_name":"Fibrosis","level":2,"score":0.6147744059562683},{"id":"https://openalex.org/C2778772119","wikidata":"https://www.wikidata.org/wiki/Q6058862","display_name":"Fatty liver","level":3,"score":0.5859602689743042},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.5610846877098083},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.4751075208187103},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.46807584166526794},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.45109084248542786},{"id":"https://openalex.org/C2780578515","wikidata":"https://www.wikidata.org/wiki/Q657193","display_name":"Metabolic syndrome","level":3,"score":0.42553460597991943},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.4083346128463745},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.3573375344276428},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.13531887531280518},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.06683623790740967},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001706","descriptor_name":"Biopsy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003937","descriptor_name":"Diagnosis, Differential","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005234","descriptor_name":"Fatty Liver","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D005234","descriptor_name":"Fatty Liver","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D005234","descriptor_name":"Fatty Liver","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D005234","descriptor_name":"Fatty Liver","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D005355","descriptor_name":"Fibrosis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015995","descriptor_name":"Prevalence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D024821","descriptor_name":"Metabolic Syndrome","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1038/nrgastro.2010.21","doi":"https://doi.org/10.1038/nrgastro.2010.21","is_oa":false,"landing_page_url":"https://doi.org/10.1038/nrgastro.2010.21","pdf_url":null,"source":{"id":"https://openalex.org/S120397320","display_name":"Nature Reviews Gastroenterology & Hepatology","issn_l":"1759-5045","issn":["1759-5045","1759-5053"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Reviews Gastroenterology &amp; Hepatology","raw_type":"journal-article"},{"id":"pmid:20195271","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20195271","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature reviews. Gastroenterology & hepatology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":119,"referenced_works":["https://openalex.org/W180027197","https://openalex.org/W197723597","https://openalex.org/W1517538469","https://openalex.org/W1825816233","https://openalex.org/W1963543568","https://openalex.org/W1965307211","https://openalex.org/W1965538010","https://openalex.org/W1966224744","https://openalex.org/W1969295126","https://openalex.org/W1970992278","https://openalex.org/W1976173209","https://openalex.org/W1982185707","https://openalex.org/W1982231111","https://openalex.org/W1983417944","https://openalex.org/W1983555286","https://openalex.org/W1984340206","https://openalex.org/W1988208946","https://openalex.org/W1988826453","https://openalex.org/W1995248922","https://openalex.org/W2001671445","https://openalex.org/W2001837599","https://openalex.org/W2003062998","https://openalex.org/W2005666028","https://openalex.org/W2006560627","https://openalex.org/W2007505836","https://openalex.org/W2009023378","https://openalex.org/W2009886169","https://openalex.org/W2013085780","https://openalex.org/W2016109557","https://openalex.org/W2017511982","https://openalex.org/W2019093082","https://openalex.org/W2024533096","https://openalex.org/W2025163736","https://openalex.org/W2026169386","https://openalex.org/W2027524383","https://openalex.org/W2030666214","https://openalex.org/W2034188379","https://openalex.org/W2037605083","https://openalex.org/W2039615324","https://openalex.org/W2042081120","https://openalex.org/W2043610882","https://openalex.org/W2044136233","https://openalex.org/W2045308683","https://openalex.org/W2045510578","https://openalex.org/W2047257800","https://openalex.org/W2048338554","https://openalex.org/W2049923191","https://openalex.org/W2050367310","https://openalex.org/W2054912517","https://openalex.org/W2056618929","https://openalex.org/W2058001096","https://openalex.org/W2064459152","https://openalex.org/W2065054228","https://openalex.org/W2065157689","https://openalex.org/W2066472395","https://openalex.org/W2067740038","https://openalex.org/W2068980784","https://openalex.org/W2075002506","https://openalex.org/W2075571367","https://openalex.org/W2077071754","https://openalex.org/W2077684198","https://openalex.org/W2077722924","https://openalex.org/W2077963393","https://openalex.org/W2078391210","https://openalex.org/W2078924987","https://openalex.org/W2081324449","https://openalex.org/W2083594174","https://openalex.org/W2084793924","https://openalex.org/W2087265885","https://openalex.org/W2087422487","https://openalex.org/W2087829753","https://openalex.org/W2088426312","https://openalex.org/W2089039539","https://openalex.org/W2090036126","https://openalex.org/W2092383091","https://openalex.org/W2092695592","https://openalex.org/W2093590019","https://openalex.org/W2095205890","https://openalex.org/W2098555833","https://openalex.org/W2105901973","https://openalex.org/W2110403671","https://openalex.org/W2112496618","https://openalex.org/W2114168045","https://openalex.org/W2114707445","https://openalex.org/W2119049152","https://openalex.org/W2120775018","https://openalex.org/W2121376063","https://openalex.org/W2122631753","https://openalex.org/W2126077627","https://openalex.org/W2128065481","https://openalex.org/W2128157888","https://openalex.org/W2136847524","https://openalex.org/W2139242094","https://openalex.org/W2141990515","https://openalex.org/W2144321671","https://openalex.org/W2147442459","https://openalex.org/W2147893167","https://openalex.org/W2149342673","https://openalex.org/W2156792510","https://openalex.org/W2157162247","https://openalex.org/W2164898770","https://openalex.org/W2168535299","https://openalex.org/W2168647804","https://openalex.org/W2168898273","https://openalex.org/W2169598496","https://openalex.org/W2171172585","https://openalex.org/W2171233986","https://openalex.org/W2185917571","https://openalex.org/W2313004210","https://openalex.org/W2607031541","https://openalex.org/W2615637571","https://openalex.org/W2905131339","https://openalex.org/W4238251256","https://openalex.org/W4246228784","https://openalex.org/W4246253507","https://openalex.org/W4249825849","https://openalex.org/W4255639460","https://openalex.org/W4285719527","https://openalex.org/W4367155260"],"related_works":["https://openalex.org/W3144776074","https://openalex.org/W2107619792","https://openalex.org/W1976137269","https://openalex.org/W2271384303","https://openalex.org/W2004409501","https://openalex.org/W2019317175","https://openalex.org/W2004998643","https://openalex.org/W1995507961","https://openalex.org/W2008274310","https://openalex.org/W1856581299"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":19},{"year":2024,"cited_by_count":24},{"year":2023,"cited_by_count":25},{"year":2022,"cited_by_count":24},{"year":2021,"cited_by_count":27},{"year":2020,"cited_by_count":35},{"year":2019,"cited_by_count":31},{"year":2018,"cited_by_count":38},{"year":2017,"cited_by_count":30},{"year":2016,"cited_by_count":31},{"year":2015,"cited_by_count":33},{"year":2014,"cited_by_count":44},{"year":2013,"cited_by_count":37},{"year":2012,"cited_by_count":32}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}
