{"id":"https://openalex.org/W2090429906","doi":"https://doi.org/10.1038/sj.onc.1210243","title":"Cell-specific responses to loss of cyclin-dependent kinases","display_name":"Cell-specific responses to loss of cyclin-dependent kinases","publication_year":2007,"publication_date":"2007-02-05","ids":{"openalex":"https://openalex.org/W2090429906","doi":"https://doi.org/10.1038/sj.onc.1210243","mag":"2090429906","pmid":"https://pubmed.ncbi.nlm.nih.gov/17297466"},"language":"en","primary_location":{"id":"doi:10.1038/sj.onc.1210243","doi":"https://doi.org/10.1038/sj.onc.1210243","is_oa":false,"landing_page_url":"https://doi.org/10.1038/sj.onc.1210243","pdf_url":null,"source":{"id":"https://openalex.org/S128439998","display_name":"Oncogene","issn_l":"0950-9232","issn":["0950-9232","1476-5594"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncogene","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032163349","display_name":"Cyril Berthet","orcid":"https://orcid.org/0000-0003-3166-3141","observed_orcids":["https://orcid.org/0000-0003-3166-3141"]},"institutions":[{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4210149717","display_name":"Center for Cancer Research","ror":"https://ror.org/05bjen692","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4210149717"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C Berthet","raw_affiliation_strings":["Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute-Frederick, Frederick, MD 21702-1201, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute-Frederick, Frederick, MD 21702-1201, USA","institution_ids":["https://openalex.org/I4210140884","https://openalex.org/I4210149717"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055174616","display_name":"Philipp Kaldis","orcid":"https://orcid.org/0000-0002-7247-7591","observed_orcids":["https://orcid.org/0000-0002-7247-7591"]},"institutions":[{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4210149717","display_name":"Center for Cancer Research","ror":"https://ror.org/05bjen692","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4210149717"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"P Kaldis","raw_affiliation_strings":["Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute-Frederick, Frederick, MD, USA","Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute-Frederick, Frederick, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute-Frederick, Frederick, MD, USA","institution_ids":["https://openalex.org/I4210140884","https://openalex.org/I4210149717"]},{"raw_affiliation_string":"Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute-Frederick, Frederick, USA","institution_ids":["https://openalex.org/I4210140884","https://openalex.org/I4210149717"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5055174616"],"corresponding_institution_ids":["https://openalex.org/I4210140884","https://openalex.org/I4210149717"],"apc_list":{"value":5990,"currency":"USD","value_usd":5990},"apc_paid":null,"fwci":1.2394,"has_fulltext":false,"cited_by_count":88,"citation_normalized_percentile":{"value":0.75353686,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"26","issue":"31","first_page":"4469","last_page":"4477"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10583","display_name":"Cancer-related Molecular Pathways","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10583","display_name":"Cancer-related Molecular Pathways","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12620","display_name":"Signaling Pathways in Disease","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cyclin-dependent-kinases","display_name":"cyclin-dependent kinases","score":1.0},{"id":"https://openalex.org/keywords/cyclins","display_name":"cyclins","score":0.9240000247955322},{"id":"https://openalex.org/keywords/cell-cycle-regulation","display_name":"cell cycle regulation","score":0.9829999804496765},{"id":"https://openalex.org/keywords/functional-redundancy","display_name":"functional redundancy","score":0.8140000104904175},{"id":"https://openalex.org/keywords/cell-type-specificity","display_name":"cell type specificity","score":0.6309999823570251},{"id":"https://openalex.org/keywords/embryonic-cells","display_name":"embryonic cells","score":0.8180000185966492},{"id":"https://openalex.org/keywords/differentiated-cells","display_name":"differentiated cells","score":0.9660000205039978},{"id":"https://openalex.org/keywords/cancer-cells","display_name":"cancer cells","score":0.6549999713897705},{"id":"https://openalex.org/keywords/cancer-therapy","display_name":"cancer therapy","score":0.7559999823570251},{"id":"https://openalex.org/keywords/stem-cells","display_name":"stem cells","score":0.7329999804496765},{"id":"https://openalex.org/keywords/kinase-inhibition","display_name":"kinase inhibition","score":0.6069999933242798}],"concepts":[{"id":"https://openalex.org/C124320809","wikidata":"https://www.wikidata.org/wiki/Q46292","display_name":"Cyclin-dependent kinase","level":4,"score":0.9264154434204102},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8033908009529114},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6751754879951477},{"id":"https://openalex.org/C29537977","wikidata":"https://www.wikidata.org/wiki/Q188941","display_name":"Cell cycle","level":3,"score":0.6460825800895691},{"id":"https://openalex.org/C120089663","wikidata":"https://www.wikidata.org/wiki/Q59250999","display_name":"Cyclin","level":4,"score":0.6075974702835083},{"id":"https://openalex.org/C184235292","wikidata":"https://www.wikidata.org/wiki/Q421851","display_name":"Kinase","level":2,"score":0.5527538061141968},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.42988765239715576},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3539513945579529},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.3299463987350464},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.14764046669006348}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002453","descriptor_name":"Cell Cycle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016213","descriptor_name":"Cyclins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016923","descriptor_name":"Cell Death","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018844","descriptor_name":"Cyclin-Dependent Kinases","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":true},{"descriptor_ui":"D020868","descriptor_name":"Gene Silencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053595","descriptor_name":"Embryonic Stem Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1038/sj.onc.1210243","doi":"https://doi.org/10.1038/sj.onc.1210243","is_oa":false,"landing_page_url":"https://doi.org/10.1038/sj.onc.1210243","pdf_url":null,"source":{"id":"https://openalex.org/S128439998","display_name":"Oncogene","issn_l":"0950-9232","issn":["0950-9232","1476-5594"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncogene","raw_type":"journal-article"},{"id":"pmid:17297466","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17297466","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncogene","raw_type":"Journal Article"},{"id":"pmh:oai:lup.lub.lu.se:ddacffd8-4659-4c27-a8db-8e88587f596e","doi":null,"is_oa":false,"landing_page_url":"https://lup.lub.lu.se/record/ddacffd8-4659-4c27-a8db-8e88587f596e","pdf_url":null,"source":{"id":"https://openalex.org/S4306400536","display_name":"Lund University Publications (Lund University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I187531555","host_organization_name":"Lund University","host_organization_lineage":["https://openalex.org/I187531555"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Oncogene; 26(31), pp 4469-4477 (2007)","raw_type":"contributiontojournal/systematicreview"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8999999761581421}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.7699999809265137}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":82,"referenced_works":["https://openalex.org/W134790102","https://openalex.org/W1520222296","https://openalex.org/W1591789003","https://openalex.org/W1871919982","https://openalex.org/W1929283771","https://openalex.org/W1932315029","https://openalex.org/W1938171108","https://openalex.org/W1965223939","https://openalex.org/W1965226888","https://openalex.org/W1966383348","https://openalex.org/W1966567463","https://openalex.org/W1970456090","https://openalex.org/W1970465585","https://openalex.org/W1973886069","https://openalex.org/W1976863434","https://openalex.org/W1990750564","https://openalex.org/W1994643441","https://openalex.org/W1999082138","https://openalex.org/W1999303173","https://openalex.org/W2001004678","https://openalex.org/W2003137016","https://openalex.org/W2004391147","https://openalex.org/W2015276971","https://openalex.org/W2017235640","https://openalex.org/W2020330574","https://openalex.org/W2022387751","https://openalex.org/W2023553115","https://openalex.org/W2024209230","https://openalex.org/W2028468783","https://openalex.org/W2028612559","https://openalex.org/W2029350002","https://openalex.org/W2030963645","https://openalex.org/W2035273416","https://openalex.org/W2049628649","https://openalex.org/W2055077352","https://openalex.org/W2058705034","https://openalex.org/W2058891255","https://openalex.org/W2059568263","https://openalex.org/W2063329265","https://openalex.org/W2063669247","https://openalex.org/W2066392676","https://openalex.org/W2067117191","https://openalex.org/W2067397461","https://openalex.org/W2074113171","https://openalex.org/W2075084906","https://openalex.org/W2083561654","https://openalex.org/W2088120691","https://openalex.org/W2088470725","https://openalex.org/W2089648262","https://openalex.org/W2089975983","https://openalex.org/W2090945807","https://openalex.org/W2094859123","https://openalex.org/W2096770011","https://openalex.org/W2098953839","https://openalex.org/W2099724117","https://openalex.org/W2101960180","https://openalex.org/W2104767521","https://openalex.org/W2104775085","https://openalex.org/W2107245612","https://openalex.org/W2107570915","https://openalex.org/W2113604152","https://openalex.org/W2116711648","https://openalex.org/W2118475358","https://openalex.org/W2121619780","https://openalex.org/W2125267517","https://openalex.org/W2127998424","https://openalex.org/W2137898468","https://openalex.org/W2147746178","https://openalex.org/W2155609574","https://openalex.org/W2156555850","https://openalex.org/W2163018106","https://openalex.org/W2169106672","https://openalex.org/W2169927110","https://openalex.org/W2170578522","https://openalex.org/W2171317581","https://openalex.org/W2315073299","https://openalex.org/W2325068802","https://openalex.org/W2395959362","https://openalex.org/W2411399255","https://openalex.org/W2413116772","https://openalex.org/W2418192776","https://openalex.org/W3024398090"],"related_works":["https://openalex.org/W2035273416","https://openalex.org/W1971732321","https://openalex.org/W4234945487","https://openalex.org/W2014613601","https://openalex.org/W2162429172","https://openalex.org/W1795737833","https://openalex.org/W2017120709","https://openalex.org/W4214766086","https://openalex.org/W7114808077","https://openalex.org/W185416544"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":8}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}