{"id":"https://openalex.org/W2090172013","doi":"https://doi.org/10.5551/jat.11452","title":"Background to Discuss Guidelines for Control of Plasma HDL-Cholesterol in Japan*","display_name":"Background to Discuss Guidelines for Control of Plasma HDL-Cholesterol in Japan*","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W2090172013","doi":"https://doi.org/10.5551/jat.11452","mag":"2090172013","pmid":"https://pubmed.ncbi.nlm.nih.gov/22240911"},"language":"en","primary_location":{"id":"doi:10.5551/jat.11452","doi":"https://doi.org/10.5551/jat.11452","is_oa":true,"landing_page_url":"https://doi.org/10.5551/jat.11452","pdf_url":"https://www.jstage.jst.go.jp/article/jat/19/3/19_11452/_pdf","source":{"id":"https://openalex.org/S140063188","display_name":"Journal of Atherosclerosis and Thrombosis","issn_l":"1340-3478","issn":["1340-3478","1880-3873"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","medline","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310313348","host_organization_name":"Japan Atherosclerosis Society","host_organization_lineage":["https://openalex.org/P4310313348"],"host_organization_lineage_names":["Japan Atherosclerosis Society"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Atherosclerosis and Thrombosis","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.jstage.jst.go.jp/article/jat/19/3/19_11452/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101897882","display_name":"Shinji Yokoyama","orcid":"https://orcid.org/0000-0003-0552-9168","observed_orcids":["https://orcid.org/0000-0003-0552-9168"]},"institutions":[{"id":"https://openalex.org/I184937672","display_name":"Chubu University","ror":"https://ror.org/02sps0775","country_code":"JP","type":"education","lineage":["https://openalex.org/I184937672"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shinji Yokoyama","raw_affiliation_strings":["Food and Nutritional Sciences, College of Bioscience and Biotechnology, Chubu University, Kasugai, Japan. syokoyam@med.nagoya-cu.ac.jp","Food and Nutritional Sciences, College of Bioscience and Biotechnology, Chubu University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Food and Nutritional Sciences, College of Bioscience and Biotechnology, Chubu University, Kasugai, Japan. syokoyam@med.nagoya-cu.ac.jp","institution_ids":["https://openalex.org/I184937672"]},{"raw_affiliation_string":"Food and Nutritional Sciences, College of Bioscience and Biotechnology, Chubu University","institution_ids":["https://openalex.org/I184937672"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103268361","display_name":"Shizuya Yamashita","orcid":"https://orcid.org/0000-0002-8413-5468","observed_orcids":["https://orcid.org/0000-0002-8413-5468"]},"institutions":[{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shizuya Yamashita","raw_affiliation_strings":["Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine","institution_ids":["https://openalex.org/I98285908"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058350680","display_name":"Shun Ishibashi","orcid":"https://orcid.org/0000-0002-1063-1979","observed_orcids":["https://orcid.org/0000-0002-1063-1979"]},"institutions":[{"id":"https://openalex.org/I146500386","display_name":"Jichi Medical University","ror":"https://ror.org/010hz0g26","country_code":"JP","type":"education","lineage":["https://openalex.org/I146500386"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shun Ishibashi","raw_affiliation_strings":["Division of Endocrinology and Metabolism, Diabetes Center, Department of Medicine, Jichi Medical University Graduate School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Endocrinology and Metabolism, Diabetes Center, Department of Medicine, Jichi Medical University Graduate School of Medicine","institution_ids":["https://openalex.org/I146500386"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037174575","display_name":"Hirohito Sone","orcid":"https://orcid.org/0000-0003-1263-2817","observed_orcids":["https://orcid.org/0000-0003-1263-2817"]},"institutions":[{"id":"https://openalex.org/I146399215","display_name":"University of Tsukuba","ror":"https://ror.org/02956yf07","country_code":"JP","type":"education","lineage":["https://openalex.org/I146399215"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hirohito Sone","raw_affiliation_strings":["Department of Endocrinology and Metabolism, Graduate School of Comprehensive Human Sciences, University of Tsukuba"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology and Metabolism, Graduate School of Comprehensive Human Sciences, University of Tsukuba","institution_ids":["https://openalex.org/I146399215"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002373909","display_name":"Shinichi Oikawa","orcid":"https://orcid.org/0000-0003-2160-3807","observed_orcids":["https://orcid.org/0000-0003-2160-3807"]},"institutions":[{"id":"https://openalex.org/I80188885","display_name":"Nippon Medical School","ror":"https://ror.org/00krab219","country_code":"JP","type":"education","lineage":["https://openalex.org/I80188885"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shinichi Oikawa","raw_affiliation_strings":["Division of Endocrinology and Metabolism, Department of Medicine, Nippon Medical School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Endocrinology and Metabolism, Department of Medicine, Nippon Medical School","institution_ids":["https://openalex.org/I80188885"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067417455","display_name":"Kohji Shirai","orcid":"https://orcid.org/0000-0003-1189-2668","observed_orcids":["https://orcid.org/0000-0003-1189-2668"]},"institutions":[{"id":"https://openalex.org/I129634264","display_name":"Toho University","ror":"https://ror.org/02hcx7n63","country_code":"JP","type":"education","lineage":["https://openalex.org/I129634264"]},{"id":"https://openalex.org/I4210125448","display_name":"Toho University Medical Center Sakura Hospital","ror":"https://ror.org/02xrm8w90","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210125448"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kohji Shirai","raw_affiliation_strings":["Internal Medicine, Sakura Hospital, School of Medicine, Toho University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Internal Medicine, Sakura Hospital, School of Medicine, Toho University","institution_ids":["https://openalex.org/I129634264","https://openalex.org/I4210125448"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Takao Ohta","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32915989","display_name":"University of the Ryukyus","ror":"https://ror.org/02z1n9q24","country_code":"JP","type":"education","lineage":["https://openalex.org/I32915989"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takao Ohta","raw_affiliation_strings":["Department of Child Health and Welfare (Pediatrics), Faculty of Medicine, University of the Ryukyus"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Child Health and Welfare (Pediatrics), Faculty of Medicine, University of the Ryukyus","institution_ids":["https://openalex.org/I32915989"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035797354","display_name":"Hideaki Bujo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159385669","display_name":"Chiba University","ror":"https://ror.org/01hjzeq58","country_code":"JP","type":"education","lineage":["https://openalex.org/I159385669"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hideaki Bujo","raw_affiliation_strings":["Department of Genome Research and Clinical Application, Chiba University Graduate School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genome Research and Clinical Application, Chiba University Graduate School of Medicine","institution_ids":["https://openalex.org/I159385669"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063363434","display_name":"Junji Kobayashi","orcid":"https://orcid.org/0000-0002-5064-730X","observed_orcids":["https://orcid.org/0000-0002-5064-730X","https://orcid.org/0009-0002-4191-8398"]},"institutions":[{"id":"https://openalex.org/I10091056","display_name":"Kanazawa University","ror":"https://ror.org/02hwp6a56","country_code":"JP","type":"education","lineage":["https://openalex.org/I10091056"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Junji Kobayashi","raw_affiliation_strings":["Department of Lipidology, Kanazawa University Graduate School of Medical Science"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Lipidology, Kanazawa University Graduate School of Medical Science","institution_ids":["https://openalex.org/I10091056"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076061467","display_name":"Hidenori Arai","orcid":"https://orcid.org/0000-0002-9000-6849","observed_orcids":["https://orcid.org/0000-0002-9000-6849","https://orcid.org/0000-0001-6747-8680"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hidenori Arai","raw_affiliation_strings":["Department of Human Health Sciences, Kyoto University Graduate School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Human Health Sciences, Kyoto University Graduate School of Medicine","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028921297","display_name":"Mariko Harada\u2010Shiba","orcid":"https://orcid.org/0000-0002-7600-2059","observed_orcids":["https://orcid.org/0000-0002-7600-2059"]},"institutions":[{"id":"https://openalex.org/I4405286384","display_name":"National Cerebral and Cardiovascular Center Research Institute","ror":"https://ror.org/01zywn143","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210111404","https://openalex.org/I4405286384"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mariko Harada-Shiba","raw_affiliation_strings":["Department of Molecular Innovation in Lipidology, National Cerebral and Cardiovascular Center Research Institute"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Innovation in Lipidology, National Cerebral and Cardiovascular Center Research Institute","institution_ids":["https://openalex.org/I4405286384"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105421753","display_name":"Masaaki Eto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I30181195","display_name":"Ohu University","ror":"https://ror.org/01fe6f215","country_code":"JP","type":"education","lineage":["https://openalex.org/I30181195"]},{"id":"https://openalex.org/I4405285365","display_name":"Ohu University Hospital","ror":"https://ror.org/059njsq80","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405285365"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masaaki Eto","raw_affiliation_strings":["School of Pharmaceutical Sciences, Ohu University and Department of Medicine, Ohu University Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmaceutical Sciences, Ohu University and Department of Medicine, Ohu University Hospital","institution_ids":["https://openalex.org/I30181195","https://openalex.org/I4405285365"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101471672","display_name":"Toshio Hayashi","orcid":"https://orcid.org/0000-0002-7711-2700","observed_orcids":["https://orcid.org/0000-0002-7711-2700"]},"institutions":[{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toshio Hayashi","raw_affiliation_strings":["Department of Geriatrics, Nagoya University Graduate School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Geriatrics, Nagoya University Graduate School of Medicine","institution_ids":["https://openalex.org/I60134161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036115796","display_name":"Takanari Gotoda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210109338","display_name":"University of Tokyo Hospital","ror":"https://ror.org/022cvpj02","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210109338"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takanari Gotoda","raw_affiliation_strings":["Department of Clinical and Molecular Epidemiology, 22nd Century Medical and Research Center, University of Tokyo Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical and Molecular Epidemiology, 22nd Century Medical and Research Center, University of Tokyo Hospital","institution_ids":["https://openalex.org/I4210109338"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090944310","display_name":"Hiroaki Suzuki","orcid":"https://orcid.org/0000-0003-0442-3687","observed_orcids":["https://orcid.org/0000-0003-0442-3687"]},"institutions":[{"id":"https://openalex.org/I146399215","display_name":"University of Tsukuba","ror":"https://ror.org/02956yf07","country_code":"JP","type":"education","lineage":["https://openalex.org/I146399215"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroaki Suzuki","raw_affiliation_strings":["Department of Endocrinology and Metabolism, Graduate School of Comprehensive Human Sciences, University of Tsukuba"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology and Metabolism, Graduate School of Comprehensive Human Sciences, University of Tsukuba","institution_ids":["https://openalex.org/I146399215"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110272934","display_name":"Nobuhiro Yamada","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146399215","display_name":"University of Tsukuba","ror":"https://ror.org/02956yf07","country_code":"JP","type":"education","lineage":["https://openalex.org/I146399215"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Nobuhiro Yamada","raw_affiliation_strings":["University of Tsukuba"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Tsukuba","institution_ids":["https://openalex.org/I146399215"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":16,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.6194,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.7215889,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"19","issue":"3","first_page":"207","last_page":"212"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11618","display_name":"Cholesterol and Lipid Metabolism","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12975","display_name":"Paraoxonase enzyme and polymorphisms","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hdl-cholesterol","display_name":"HDL cholesterol","score":0.9760000109672546},{"id":"https://openalex.org/keywords/atherosclerosis-risk","display_name":"atherosclerosis risk","score":0.6340000033378601},{"id":"https://openalex.org/keywords/ischemic-heart-disease","display_name":"ischemic heart disease","score":0.8140000104904175},{"id":"https://openalex.org/keywords/low-hdl-cholesterol","display_name":"low HDL cholesterol","score":0.6320000290870667},{"id":"https://openalex.org/keywords/cetp-deficiency","display_name":"CETP deficiency","score":0.6639999747276306},{"id":"https://openalex.org/keywords/hypertriglyceridemia","display_name":"hypertriglyceridemia","score":0.6340000033378601},{"id":"https://openalex.org/keywords/japan","display_name":"Japan","score":0.3610000014305115}],"concepts":[{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.6577638387680054},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.6393913626670837},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6357347369194031},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5767929553985596},{"id":"https://openalex.org/C2780182762","wikidata":"https://www.wikidata.org/wiki/Q1630279","display_name":"Guideline","level":2,"score":0.5753843784332275},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.5488057136535645},{"id":"https://openalex.org/C2780541478","wikidata":"https://www.wikidata.org/wiki/Q410020","display_name":"High-density lipoprotein","level":3,"score":0.518955409526825},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.44709885120391846},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.44663071632385254},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.36702167987823486},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.09239500761032104},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007564","descriptor_name":"Japan","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008076","descriptor_name":"Cholesterol, HDL","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D008078","descriptor_name":"Cholesterol, LDL","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017202","descriptor_name":"Myocardial Ischemia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D017202","descriptor_name":"Myocardial Ischemia","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D017202","descriptor_name":"Myocardial Ischemia","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D017410","descriptor_name":"Practice Guidelines as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053480","descriptor_name":"Cholesterol Ester Transfer Proteins","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.5551/jat.11452","doi":"https://doi.org/10.5551/jat.11452","is_oa":true,"landing_page_url":"https://doi.org/10.5551/jat.11452","pdf_url":"https://www.jstage.jst.go.jp/article/jat/19/3/19_11452/_pdf","source":{"id":"https://openalex.org/S140063188","display_name":"Journal of Atherosclerosis and Thrombosis","issn_l":"1340-3478","issn":["1340-3478","1880-3873"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","medline","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310313348","host_organization_name":"Japan Atherosclerosis Society","host_organization_lineage":["https://openalex.org/P4310313348"],"host_organization_lineage_names":["Japan Atherosclerosis Society"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Atherosclerosis and Thrombosis","raw_type":"journal-article"},{"id":"pmid:22240911","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22240911","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of atherosclerosis and thrombosis","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.5551/jat.11452","doi":"https://doi.org/10.5551/jat.11452","is_oa":true,"landing_page_url":"https://doi.org/10.5551/jat.11452","pdf_url":"https://www.jstage.jst.go.jp/article/jat/19/3/19_11452/_pdf","source":{"id":"https://openalex.org/S140063188","display_name":"Journal of Atherosclerosis and Thrombosis","issn_l":"1340-3478","issn":["1340-3478","1880-3873"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","medline","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310313348","host_organization_name":"Japan Atherosclerosis Society","host_organization_lineage":["https://openalex.org/P4310313348"],"host_organization_lineage_names":["Japan Atherosclerosis Society"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Atherosclerosis and Thrombosis","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1001640741","display_name":"Investigation of the regression of advanced atherosclerosis through the regulation of cellular senescence-custom-made therapy to Japanese elderly-","funder_award_id":"21590762","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G3970412451","display_name":"Elucidation of the roles of Neuromedin U on development of atherosclerosis and its therapeutic application","funder_award_id":"22591004","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G7274736314","display_name":"Geriatric and gerontological approach for asian elderly to prevent their atherosclerotic disease and get successful aging.","funder_award_id":"20406004","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G7814373260","display_name":"Nutritional regulation of sterol metabolism in development of lifestyle-related diseases","funder_award_id":"24614018","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G8227378529","display_name":"Establishing clinical evidence for prevention of lifestyle-related disease and lifestyle intervention","funder_award_id":"20300227","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2090172013.pdf","grobid_xml":"https://content.openalex.org/works/W2090172013.grobid-xml"},"referenced_works_count":17,"referenced_works":["https://openalex.org/W1913193828","https://openalex.org/W1971507375","https://openalex.org/W1992000409","https://openalex.org/W2004878568","https://openalex.org/W2027231471","https://openalex.org/W2042833670","https://openalex.org/W2048760408","https://openalex.org/W2056187860","https://openalex.org/W2059048963","https://openalex.org/W2088299322","https://openalex.org/W2103025142","https://openalex.org/W2122049307","https://openalex.org/W2126678006","https://openalex.org/W2127104460","https://openalex.org/W2151720705","https://openalex.org/W2336122760","https://openalex.org/W2747216020"],"related_works":["https://openalex.org/W2082722871","https://openalex.org/W2794522988","https://openalex.org/W2037793313","https://openalex.org/W2395162572","https://openalex.org/W2106601510","https://openalex.org/W2042341024","https://openalex.org/W2528274397","https://openalex.org/W2119240687","https://openalex.org/W3015833589","https://openalex.org/W1982459763"],"abstract_inverted_index":{"A":[0],"decrease":[1],"in":[2,15,23,98,125,143],"high":[3],"density":[4,25],"lipoprotein-cholesterol":[5,26],"(HDL-C)":[6],"is":[7,65,107,117],"a":[8,123,199],"strong":[9],"risk":[10,102,189,200],"factor":[11],"for":[12,33,169],"atherosclerotic":[13],"disorders":[14],"Japan,":[16],"probably":[17,156],"more":[18],"important":[19],"than":[20,77],"an":[21,54,203],"increase":[22,201],"low":[24],"(LDL-C).":[27],"While":[28,115],"there":[29,44,116,164],"are":[30,165],"rational":[31],"grounds":[32],"the":[34,61,68,90,101,128,136,139,141,144,149,154,196],"argument":[35],"that":[36,85,120],"elevation":[37,57],"of":[38,52,58,71,92,130,148,198],"HDL-C":[39,59,72,106,137,150,206],"leads":[40],"to":[41,160,194],"decreased":[42],"risk,":[43,62,155],"has":[45],"as":[46,110,192],"yet":[47],"been":[48],"no":[49,118,166],"direct":[50],"evidence":[51,119],"such":[53],"effect.":[55],"If":[56],"decreases":[60],"this":[63,126,170],"effect":[64,171],"expected":[66],"throughout":[67],"normal":[69],"range":[70],"or":[73,113],"perhaps":[74],"even":[75],"higher":[76,135],"that.":[78],"Simulation":[79],"based":[80],"on":[81],"epidemiological":[82,131],"data":[83,168],"indicated":[84],"it":[86],"may":[87,152],"eventually":[88],"reduce":[89,153],"incidence":[91],"ischemic":[93],"heart":[94],"disease":[95],"by":[96],"60-70%":[97],"Japan.":[99],"In":[100],"management":[103],"guideline,":[104],"\"low\"":[105],"presently":[108],"defined":[109],"40":[111],"mg/dL":[112],"below.":[114],"strongly":[121],"urges":[122],"change":[124],"definition,":[127],"results":[129],"studies":[132],"support":[133],"\"The":[134],"level,":[138],"lower":[140],"risk,\"even":[142],"\"normal":[145],"range\".":[146],"Elevation":[147],"level":[151],"at":[157],"least":[158],"up":[159],"70":[161],"mg/dL;":[162],"however,":[163],"supportive":[167],"still":[172],"being":[173],"obtained":[174],"over":[175],"80":[176],"mg/dL.":[177],"Patients":[178],"with":[179,202],"homozygous":[180],"CETP":[181],"deficiency":[182],"should":[183],"be":[184],"followed-up":[185],"while":[186],"controlling":[187],"other":[188],"factors,":[190],"so":[191],"not":[193],"dismiss":[195],"possibility":[197],"extremely":[204],"elevated":[205],"level.":[207]},"counts_by_year":[{"year":2024,"cited_by_count":4},{"year":2015,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}