{"id":"https://openalex.org/W2090145657","doi":"https://doi.org/10.1111/j.1572-0241.2002.05645.x","title":"Is bezafibrate histologically effective for primary biliary cirrhosis?","display_name":"Is bezafibrate histologically effective for primary biliary cirrhosis?","publication_year":2002,"publication_date":"2002-04-01","ids":{"openalex":"https://openalex.org/W2090145657","doi":"https://doi.org/10.1111/j.1572-0241.2002.05645.x","mag":"2090145657","pmid":"https://pubmed.ncbi.nlm.nih.gov/12003404"},"language":"en","primary_location":{"id":"doi:10.1111/j.1572-0241.2002.05645.x","doi":"https://doi.org/10.1111/j.1572-0241.2002.05645.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1572-0241.2002.05645.x","pdf_url":null,"source":{"id":"https://openalex.org/S66441642","display_name":"The American Journal of Gastroenterology","issn_l":"0002-9270","issn":["0002-9270","1572-0241"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Gastroenterology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102851819","display_name":"Koji Yano","orcid":"https://orcid.org/0000-0003-0133-8313","observed_orcids":["https://orcid.org/0000-0003-0133-8313"]},"institutions":[{"id":"https://openalex.org/I4210118695","display_name":"Nagasaki Medical Center","ror":"https://ror.org/02qv90y91","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210118695","https://openalex.org/I4210137409"]},{"id":"https://openalex.org/I4405284692","display_name":"Japanese Red Cross Nagasaki Genbaku Hospital","ror":"https://ror.org/041r2wa07","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I2799517759","https://openalex.org/I4405284692"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Koji Yano","raw_affiliation_strings":["Division of Gastroenterology, Japanese Red Cross, Nagasaki Genbaku Hospital, Nagasaki, Japan","Koji Yano, MD, National Nagasaki Medical Center, 2-1001-1 Kubara, Omura, Nagasaki 856-8562, Japan","\"Division of Gastroenterology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, Japanese Red Cross, Nagasaki Genbaku Hospital, Nagasaki, Japan","institution_ids":["https://openalex.org/I4405284692"]},{"raw_affiliation_string":"Koji Yano, MD, National Nagasaki Medical Center, 2-1001-1 Kubara, Omura, Nagasaki 856-8562, Japan","institution_ids":["https://openalex.org/I4210118695"]},{"raw_affiliation_string":"\"Division of Gastroenterology","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087124471","display_name":"Hiroyuki Kato","orcid":"https://orcid.org/0000-0003-0655-1519","observed_orcids":["https://orcid.org/0000-0003-0655-1519"]},"institutions":[{"id":"https://openalex.org/I4405284692","display_name":"Japanese Red Cross Nagasaki Genbaku Hospital","ror":"https://ror.org/041r2wa07","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I2799517759","https://openalex.org/I4405284692"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroyuki Kato","raw_affiliation_strings":["Division of Gastroenterology, Japanese Red Cross, Nagasaki Genbaku Hospital, Nagasaki, Japan","\"Division of Gastroenterology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, Japanese Red Cross, Nagasaki Genbaku Hospital, Nagasaki, Japan","institution_ids":["https://openalex.org/I4405284692"]},{"raw_affiliation_string":"\"Division of Gastroenterology","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Shigeki Morita","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405284692","display_name":"Japanese Red Cross Nagasaki Genbaku Hospital","ror":"https://ror.org/041r2wa07","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I2799517759","https://openalex.org/I4405284692"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shigeki Morita","raw_affiliation_strings":["Division of Gastroenterology, Japanese Red Cross, Nagasaki Genbaku Hospital, Nagasaki, Japan","\"Division of Gastroenterology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, Japanese Red Cross, Nagasaki Genbaku Hospital, Nagasaki, Japan","institution_ids":["https://openalex.org/I4405284692"]},{"raw_affiliation_string":"\"Division of Gastroenterology","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006673733","display_name":"Osamu Takahara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405284692","display_name":"Japanese Red Cross Nagasaki Genbaku Hospital","ror":"https://ror.org/041r2wa07","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I2799517759","https://openalex.org/I4405284692"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Osamu Takahara","raw_affiliation_strings":["Division of Pathology Japanese Red Cross, Nagasaki Genbaku Hospital, Nagasaki, Japan","\"Division of Pathology Japanese Red Cross"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pathology Japanese Red Cross, Nagasaki Genbaku Hospital, Nagasaki, Japan","institution_ids":["https://openalex.org/I4405284692"]},{"raw_affiliation_string":"\"Division of Pathology Japanese Red Cross","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051843684","display_name":"Hiromi Ishibashi","orcid":"https://orcid.org/0000-0002-5005-6921","observed_orcids":["https://orcid.org/0000-0002-5005-6921"]},"institutions":[{"id":"https://openalex.org/I4210118695","display_name":"Nagasaki Medical Center","ror":"https://ror.org/02qv90y91","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210118695","https://openalex.org/I4210137409"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiromi Ishibashi","raw_affiliation_strings":["Institute for Clinical Research, National Nagasaki Medical Center, Nagasaki, Japan","\"Institute for Clinical Research"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Clinical Research, National Nagasaki Medical Center, Nagasaki, Japan","institution_ids":["https://openalex.org/I4210118695"]},{"raw_affiliation_string":"\"Institute for Clinical Research","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110398560","display_name":"Ryuji FURUKAWA","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405284692","display_name":"Japanese Red Cross Nagasaki Genbaku Hospital","ror":"https://ror.org/041r2wa07","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I2799517759","https://openalex.org/I4405284692"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ryuji Furukawa","raw_affiliation_strings":["Division of Gastroenterology, Japanese Red Cross, Nagasaki Genbaku Hospital, Nagasaki, Japan","\"Division of Gastroenterology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, Japanese Red Cross, Nagasaki Genbaku Hospital, Nagasaki, Japan","institution_ids":["https://openalex.org/I4405284692"]},{"raw_affiliation_string":"\"Division of Gastroenterology","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5102851819"],"corresponding_institution_ids":["https://openalex.org/I4210118695","https://openalex.org/I4405284692"],"apc_list":{"value":4390,"currency":"USD","value_usd":4390},"apc_paid":null,"fwci":1.8326,"has_fulltext":false,"cited_by_count":55,"citation_normalized_percentile":{"value":0.85453017,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"97","issue":"4","first_page":"1075","last_page":"1077"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11834","display_name":"Liver Diseases and Immunity","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11834","display_name":"Liver Diseases and Immunity","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10570","display_name":"Drug Transport and Resistance Mechanisms","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12460","display_name":"Pediatric Hepatobiliary Diseases and Treatments","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bezafibrate","display_name":"bezafibrate","score":1.0},{"id":"https://openalex.org/keywords/primary-biliary-cholangitis","display_name":"primary biliary cirrhosis","score":0.996999979019165},{"id":"https://openalex.org/keywords/fibrosis","display_name":"fibrosis","score":0.4580000042915344},{"id":"https://openalex.org/keywords/bile-acid-sequestrants","display_name":"bile acid sequestrants","score":0.5659999847412109},{"id":"https://openalex.org/keywords/liver-histopathology","display_name":"liver histopathology","score":0.4569999873638153}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9316504001617432},{"id":"https://openalex.org/C2780366471","wikidata":"https://www.wikidata.org/wiki/Q1072420","display_name":"Primary biliary cirrhosis","level":2,"score":0.5911349058151245},{"id":"https://openalex.org/C2776362216","wikidata":"https://www.wikidata.org/wiki/Q577387","display_name":"Bezafibrate","level":2,"score":0.5829476118087769},{"id":"https://openalex.org/C2777214474","wikidata":"https://www.wikidata.org/wiki/Q147778","display_name":"Cirrhosis","level":2,"score":0.4128461480140686},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.40509453415870667},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.39371347427368164}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000960","descriptor_name":"Hypolipidemic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D001629","descriptor_name":"Bezafibrate","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008105","descriptor_name":"Liver Cirrhosis, Biliary","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D008105","descriptor_name":"Liver Cirrhosis, Biliary","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1111/j.1572-0241.2002.05645.x","doi":"https://doi.org/10.1111/j.1572-0241.2002.05645.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1572-0241.2002.05645.x","pdf_url":null,"source":{"id":"https://openalex.org/S66441642","display_name":"The American Journal of Gastroenterology","issn_l":"0002-9270","issn":["0002-9270","1572-0241"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Gastroenterology","raw_type":"journal-article"},{"id":"doi:10.1016/s0002-9270(02)04001-7","doi":"https://doi.org/10.1016/s0002-9270(02)04001-7","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0002-9270(02)04001-7","pdf_url":null,"source":{"id":"https://openalex.org/S66441642","display_name":"The American Journal of Gastroenterology","issn_l":"0002-9270","issn":["0002-9270","1572-0241"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Gastroenterology","raw_type":"journal-article"},{"id":"pmid:12003404","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12003404","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of gastroenterology","raw_type":"Case Reports"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W176315691","https://openalex.org/W239268888","https://openalex.org/W1988745496","https://openalex.org/W2024183286","https://openalex.org/W2040375465","https://openalex.org/W2074922723","https://openalex.org/W2076982518","https://openalex.org/W2104194955","https://openalex.org/W2159434940","https://openalex.org/W2324587274","https://openalex.org/W2397986877","https://openalex.org/W4236767709"],"related_works":["https://openalex.org/W1975653501","https://openalex.org/W415068427","https://openalex.org/W1984620293","https://openalex.org/W2074922723","https://openalex.org/W1974694649","https://openalex.org/W4232201040","https://openalex.org/W7075667960","https://openalex.org/W2059400296","https://openalex.org/W2017003670","https://openalex.org/W2076982518"],"abstract_inverted_index":{"Yano,":[0],"Koji":[1],"MD1;":[2,5,8],"Kato,":[3],"Hiroyuki":[4],"Morita,":[6],"Shigeki":[7],"Takahara,":[9],"Osamu":[10],"MD2;":[11],"Ishibashi,":[12],"Hiromi":[13],"MD,":[14],"FACG3;":[15],"Furukawa,":[16],"Ryuji":[17],"MD1":[18],"Author":[19],"Information":[20]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}