{"id":"https://openalex.org/W2090103344","doi":"https://doi.org/10.1016/0092-8674(91)90648-i","title":"Induction of specific storage organelles by von Willebrand factor propolypeptide","display_name":"Induction of specific storage organelles by von Willebrand factor propolypeptide","publication_year":1991,"publication_date":"1991-01-01","ids":{"openalex":"https://openalex.org/W2090103344","doi":"https://doi.org/10.1016/0092-8674(91)90648-i","mag":"2090103344","pmid":"https://pubmed.ncbi.nlm.nih.gov/1988154"},"language":"en","primary_location":{"id":"doi:10.1016/0092-8674(91)90648-i","doi":"https://doi.org/10.1016/0092-8674(91)90648-i","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0092-8674(91)90648-i","pdf_url":null,"source":{"id":"https://openalex.org/S110447773","display_name":"Cell","issn_l":"0092-8674","issn":["0092-8674","1097-4172"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032584210","display_name":"Denisa D. Wagner","orcid":"https://orcid.org/0000-0002-4494-413X","observed_orcids":["https://orcid.org/0000-0002-4494-413X"]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]},{"id":"https://openalex.org/I1290900354","display_name":"Tufts Medical Center","ror":"https://ror.org/002hsbm82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1290900354"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Denisa D Wagner","raw_affiliation_strings":["New England Medical Center, Boston, Massachusetts","New England Medical Center and Tufts University Departments of Medicine and Anatomy and Cellular Biology, Boston, Massachusetts 02111, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New England Medical Center, Boston, Massachusetts","institution_ids":["https://openalex.org/I1290900354"]},{"raw_affiliation_string":"New England Medical Center and Tufts University Departments of Medicine and Anatomy and Cellular Biology, Boston, Massachusetts 02111, USA","institution_ids":["https://openalex.org/I121934306","https://openalex.org/I1290900354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075542273","display_name":"Simin Saffaripour","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]},{"id":"https://openalex.org/I1290900354","display_name":"Tufts Medical Center","ror":"https://ror.org/002hsbm82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1290900354"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Simin Saffaripour","raw_affiliation_strings":["New England Medical Center and Tufts University Departments of Medicine and Anatomy and Cellular Biology, Boston, Massachusetts 02111, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New England Medical Center and Tufts University Departments of Medicine and Anatomy and Cellular Biology, Boston, Massachusetts 02111, USA","institution_ids":["https://openalex.org/I121934306","https://openalex.org/I1290900354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046217358","display_name":"Roberta Bonfanti","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210119095","display_name":"H\u00f4pital Lariboisi\u00e8re","ror":"https://ror.org/02mqtne57","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210119095"]},{"id":"https://openalex.org/I4210141252","display_name":"Institut des Vaisseaux et du Sang","ror":"https://ror.org/03jfptm11","country_code":"FR","type":"facility","lineage":["https://openalex.org/I4210141252"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Roberta Bonfanti","raw_affiliation_strings":["Institut des Vaisseaux et du Sang and INSERM U 150 Hopital Lariboisi\u00e8re 75010 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut des Vaisseaux et du Sang and INSERM U 150 Hopital Lariboisi\u00e8re 75010 Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210119095","https://openalex.org/I4210141252"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005704032","display_name":"J. Evan Sadler","orcid":"https://orcid.org/0000-0001-5705-469X","observed_orcids":["https://orcid.org/0000-0001-5705-469X"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J.Evan Sadler","raw_affiliation_strings":["Howard Hughes Medical Institute Washington University School of Medicine Saint Louis, Missouri 63110, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Howard Hughes Medical Institute Washington University School of Medicine Saint Louis, Missouri 63110, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068100566","display_name":"Elisabeth Martin Cramer","orcid":"https://orcid.org/0000-0001-7595-0885","observed_orcids":["https://orcid.org/0000-0001-7595-0885"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Elisabeth M Cramer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053276616","display_name":"Barbara S. Chapman","orcid":"https://orcid.org/0000-0002-1495-8573","observed_orcids":["https://orcid.org/0000-0002-1495-8573"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Barbara Chapman","raw_affiliation_strings":["Chiron Corporation Emeryville, California 94608, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chiron Corporation Emeryville, California 94608, USA","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031800389","display_name":"Tanya N. Mayadas","orcid":"https://orcid.org/0000-0003-4143-3278","observed_orcids":["https://orcid.org/0000-0003-4143-3278"]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]},{"id":"https://openalex.org/I1290900354","display_name":"Tufts Medical Center","ror":"https://ror.org/002hsbm82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1290900354"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tanya N Mayadas","raw_affiliation_strings":["New England Medical Center and Tufts University Departments of Medicine and Anatomy and Cellular Biology, Boston, Massachusetts 02111, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New England Medical Center and Tufts University Departments of Medicine and Anatomy and Cellular Biology, Boston, Massachusetts 02111, USA","institution_ids":["https://openalex.org/I121934306","https://openalex.org/I1290900354"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":11400,"currency":"USD","value_usd":11400},"apc_paid":null,"fwci":11.9562,"has_fulltext":false,"cited_by_count":272,"citation_normalized_percentile":{"value":0.99169416,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"64","issue":"2","first_page":"403","last_page":"413"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10746","display_name":"Platelet Disorders and Treatments","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10746","display_name":"Platelet Disorders and Treatments","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.009800000116229057,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/von-willebrand-factor","display_name":"von Willebrand factor","score":1.0},{"id":"https://openalex.org/keywords/weibel-palade-bodies","display_name":"Weibel-Palade bodies","score":0.9760000109672546},{"id":"https://openalex.org/keywords/storage-granules","display_name":"storage granules","score":0.8759999871253967},{"id":"https://openalex.org/keywords/endothelial-cells","display_name":"endothelial cells","score":0.7590000033378601},{"id":"https://openalex.org/keywords/regulated-secretion","display_name":"regulated secretion","score":0.8880000114440918},{"id":"https://openalex.org/keywords/granule-formation","display_name":"granule formation","score":0.5669999718666077},{"id":"https://openalex.org/keywords/platelet-plug","display_name":"platelet plug","score":0.6050000190734863},{"id":"https://openalex.org/keywords/multimeric-structure","display_name":"multimeric structure","score":0.453000009059906}],"concepts":[{"id":"https://openalex.org/C2779394231","wikidata":"https://www.wikidata.org/wiki/Q412310","display_name":"Von Willebrand factor","level":3,"score":0.8466801047325134},{"id":"https://openalex.org/C187882448","wikidata":"https://www.wikidata.org/wiki/Q283478","display_name":"Complementary DNA","level":3,"score":0.6171455979347229},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6060545444488525},{"id":"https://openalex.org/C108625454","wikidata":"https://www.wikidata.org/wiki/Q187126","display_name":"Glycoprotein","level":2,"score":0.5726765394210815},{"id":"https://openalex.org/C168240541","wikidata":"https://www.wikidata.org/wiki/Q45948","display_name":"Organelle","level":2,"score":0.5582754611968994},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.532882809638977},{"id":"https://openalex.org/C49039625","wikidata":"https://www.wikidata.org/wiki/Q84230","display_name":"Secretion","level":2,"score":0.5128417611122131},{"id":"https://openalex.org/C89560881","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet","level":2,"score":0.43409276008605957},{"id":"https://openalex.org/C2778780528","wikidata":"https://www.wikidata.org/wiki/Q709360","display_name":"Von Willebrand disease","level":4,"score":0.4326871633529663},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.37425029277801514},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2658335864543915},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.1455966830253601},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09516525268554688}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005455","descriptor_name":"Fluorescent Antibody Technique","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008854","descriptor_name":"Microscopy, Electron","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010957","descriptor_name":"Plasmids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011498","descriptor_name":"Protein Precursors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D011499","descriptor_name":"Protein Processing, Post-Translational","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014162","descriptor_name":"Transfection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014841","descriptor_name":"von Willebrand Factor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D014841","descriptor_name":"von Willebrand Factor","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D015153","descriptor_name":"Blotting, Western","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015183","descriptor_name":"Restriction Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015388","descriptor_name":"Organelles","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015388","descriptor_name":"Organelles","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0092-8674(91)90648-i","doi":"https://doi.org/10.1016/0092-8674(91)90648-i","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0092-8674(91)90648-i","pdf_url":null,"source":{"id":"https://openalex.org/S110447773","display_name":"Cell","issn_l":"0092-8674","issn":["0092-8674","1097-4172"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell","raw_type":"journal-article"},{"id":"pmid:1988154","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1988154","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G6418412604","display_name":"Weibel-Palade Bodies: roles in thrombosis, inflammation and stroke","funder_award_id":"R01HL041002","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":69,"referenced_works":["https://openalex.org/W38916664","https://openalex.org/W73759871","https://openalex.org/W105767410","https://openalex.org/W177128174","https://openalex.org/W193545656","https://openalex.org/W221678615","https://openalex.org/W271548231","https://openalex.org/W332266132","https://openalex.org/W1503860336","https://openalex.org/W1540988218","https://openalex.org/W1557940991","https://openalex.org/W1570075490","https://openalex.org/W1573154650","https://openalex.org/W1586559331","https://openalex.org/W1602599685","https://openalex.org/W1721634089","https://openalex.org/W1756091829","https://openalex.org/W1880892278","https://openalex.org/W1965372133","https://openalex.org/W1965790897","https://openalex.org/W1969984823","https://openalex.org/W1972307298","https://openalex.org/W1974175370","https://openalex.org/W1977685486","https://openalex.org/W1991078519","https://openalex.org/W1998162329","https://openalex.org/W1999063996","https://openalex.org/W1999881321","https://openalex.org/W2001873278","https://openalex.org/W2006493056","https://openalex.org/W2006943139","https://openalex.org/W2008146810","https://openalex.org/W2018339334","https://openalex.org/W2022094318","https://openalex.org/W2023501329","https://openalex.org/W2026685675","https://openalex.org/W2030712566","https://openalex.org/W2036016732","https://openalex.org/W2041871326","https://openalex.org/W2049174790","https://openalex.org/W2054657407","https://openalex.org/W2073623140","https://openalex.org/W2074819375","https://openalex.org/W2083197112","https://openalex.org/W2097165184","https://openalex.org/W2097514615","https://openalex.org/W2100837269","https://openalex.org/W2108093102","https://openalex.org/W2122400280","https://openalex.org/W2123065833","https://openalex.org/W2135189810","https://openalex.org/W2136739150","https://openalex.org/W2142480761","https://openalex.org/W2143811534","https://openalex.org/W2145120738","https://openalex.org/W2154546635","https://openalex.org/W2175263209","https://openalex.org/W2229838414","https://openalex.org/W2395410748","https://openalex.org/W2409871886","https://openalex.org/W2412997314","https://openalex.org/W2418984961","https://openalex.org/W2432391613","https://openalex.org/W2466689151","https://openalex.org/W2470860124","https://openalex.org/W2745627398","https://openalex.org/W3159335964","https://openalex.org/W6636578615","https://openalex.org/W6669165397"],"related_works":["https://openalex.org/W2406574199","https://openalex.org/W2154546635","https://openalex.org/W4298126633","https://openalex.org/W2074819375","https://openalex.org/W4233733307","https://openalex.org/W2418690188","https://openalex.org/W2790837588","https://openalex.org/W2068256509","https://openalex.org/W2075499364","https://openalex.org/W1969984823"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}