{"id":"https://openalex.org/W2089967575","doi":"https://doi.org/10.1111/j.1600-065x.1982.tb01064.x","title":"LFA\u20101 and Lyt\u20102,3, Molecules Associated with T Lymphocyte\u2010Mediated Killing; and Mac\u20101, an LFA\u20101 Homologue Associated with Complement Receptor Function1","display_name":"LFA\u20101 and Lyt\u20102,3, Molecules Associated with T Lymphocyte\u2010Mediated Killing; and Mac\u20101, an LFA\u20101 Homologue Associated with Complement Receptor Function1","publication_year":1982,"publication_date":"1982-12-01","ids":{"openalex":"https://openalex.org/W2089967575","doi":"https://doi.org/10.1111/j.1600-065x.1982.tb01064.x","mag":"2089967575","pmid":"https://pubmed.ncbi.nlm.nih.gov/6184305"},"language":"en","primary_location":{"id":"doi:10.1111/j.1600-065x.1982.tb01064.x","doi":"https://doi.org/10.1111/j.1600-065x.1982.tb01064.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1600-065x.1982.tb01064.x","pdf_url":null,"source":{"id":"https://openalex.org/S133112385","display_name":"Immunological Reviews","issn_l":"0105-2896","issn":["0105-2896","1600-065X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunological Reviews","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003615852","display_name":"Timothy A. Springer","orcid":"https://orcid.org/0000-0001-6627-2904","observed_orcids":["https://orcid.org/0000-0001-6627-2904"]},"institutions":[{"id":"https://openalex.org/I1288198617","display_name":"American Cancer Society","ror":"https://ror.org/02e463172","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1288198617"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Timothy A. Springer","raw_affiliation_strings":["Laboratory of Membrane Immunochemistry, Sidney Farber Cancer Institute, Harvard Medical School 44 Binney St., Boston, MA 02115, U.S.A","Recipient of an American Cancer Society Junior Faculty Award"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Membrane Immunochemistry, Sidney Farber Cancer Institute, Harvard Medical School 44 Binney St., Boston, MA 02115, U.S.A","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Recipient of an American Cancer Society Junior Faculty Award","institution_ids":["https://openalex.org/I1288198617"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5097340976","display_name":"Denise DAV Gnon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2800446032","display_name":"Rhode Island Hospital","ror":"https://ror.org/01aw9fv09","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800446032","https://openalex.org/I4210151747"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Denise DAV:Gnon","raw_affiliation_strings":["Department of Clinical Hematology, Rhode Island Hospital, Providence, RI 02902, U.S.A","Laboratory of Membrane Immunochemistry, Sidney Farber Cancer Institute, Harvard Medical School 44 Binney St., Boston, MA 02115, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Hematology, Rhode Island Hospital, Providence, RI 02902, U.S.A","institution_ids":["https://openalex.org/I2800446032"]},{"raw_affiliation_string":"Laboratory of Membrane Immunochemistry, Sidney Farber Cancer Institute, Harvard Medical School 44 Binney St., Boston, MA 02115, U.S.A","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084437187","display_name":"M K Ho","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"MAY\u2010KIN HO","raw_affiliation_strings":["Laboratory of Membrane Immunochemistry, Sidney Farber Cancer Institute, Harvard Medical School 44 Binney St., Boston, MA 02115, U.S.A","New England Nuclear, Boston, MA 02118. U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Membrane Immunochemistry, Sidney Farber Cancer Institute, Harvard Medical School 44 Binney St., Boston, MA 02115, U.S.A","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"New England Nuclear, Boston, MA 02118. U.S.A","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091071411","display_name":"K. K\u00fcrzinger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Konrad Kurzinger","raw_affiliation_strings":["Boehringer Mannheim, Tutzing, W. Germany","Laboratory of Membrane Immunochemistry, Sidney Farber Cancer Institute, Harvard Medical School 44 Binney St., Boston, MA 02115, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boehringer Mannheim, Tutzing, W. Germany","institution_ids":[]},{"raw_affiliation_string":"Laboratory of Membrane Immunochemistry, Sidney Farber Cancer Institute, Harvard Medical School 44 Binney St., Boston, MA 02115, U.S.A","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049555309","display_name":"Eric Martz","orcid":"https://orcid.org/0000-0003-4679-6967","observed_orcids":["https://orcid.org/0000-0003-4679-6967"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I24603500","display_name":"University of Massachusetts Amherst","ror":"https://ror.org/0072zz521","country_code":"US","type":"education","lineage":["https://openalex.org/I24603500"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric Martz","raw_affiliation_strings":["Laboratory of Membrane Immunochemistry, Sidney Farber Cancer Institute, Harvard Medical School 44 Binney St., Boston, MA 02115, U.S.A","University of Massachusetts, Department of Microbiology, Amherst, MA 01003, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Membrane Immunochemistry, Sidney Farber Cancer Institute, Harvard Medical School 44 Binney St., Boston, MA 02115, U.S.A","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"University of Massachusetts, Department of Microbiology, Amherst, MA 01003, U.S.A","institution_ids":["https://openalex.org/I24603500"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006841984","display_name":"Francisco S\u00e1nchez\u2010Madrid","orcid":"https://orcid.org/0000-0001-5303-0762","observed_orcids":["https://orcid.org/0000-0001-5303-0762"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Francisco Sanchez\u2010Madrid","raw_affiliation_strings":["Laboratory of Membrane Immunochemistry, Sidney Farber Cancer Institute, Harvard Medical School 44 Binney St., Boston, MA 02115, U.S.A","Recipient of Spanish-American and USPHS Fogarty International fellowships"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Membrane Immunochemistry, Sidney Farber Cancer Institute, Harvard Medical School 44 Binney St., Boston, MA 02115, U.S.A","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Recipient of Spanish-American and USPHS Fogarty International fellowships","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5000,"currency":"USD","value_usd":5000},"apc_paid":null,"fwci":1.46,"has_fulltext":false,"cited_by_count":223,"citation_normalized_percentile":{"value":0.875,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"68","issue":"1","first_page":"171","last_page":"196"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.9077000021934509,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.9077000021934509,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.06669999659061432,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","score":0.008100000210106373,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lfa-1","display_name":"LFA-1","score":0.996999979019165},{"id":"https://openalex.org/keywords/mac-1","display_name":"Mac-1","score":0.9110000133514404},{"id":"https://openalex.org/keywords/complement-receptor-1","display_name":"complement receptor 1","score":0.7689999938011169},{"id":"https://openalex.org/keywords/integrins","display_name":"integrins","score":0.6909999847412109},{"id":"https://openalex.org/keywords/cell-adhesion-molecules","display_name":"adhesion molecules","score":0.7279999852180481},{"id":"https://openalex.org/keywords/lymphocyte-activation","display_name":"lymphocyte activation","score":0.3919999897480011},{"id":"https://openalex.org/keywords/cell-mediated-cytotoxicity","display_name":"cell-mediated cytotoxicity","score":0.6290000081062317}],"concepts":[{"id":"https://openalex.org/C2993838110","wikidata":"https://www.wikidata.org/wiki/Q494230","display_name":"Medical school","level":2,"score":0.636739194393158},{"id":"https://openalex.org/C2780659158","wikidata":"https://www.wikidata.org/wiki/Q2466273","display_name":"Immunochemistry","level":3,"score":0.6225312352180481},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.29863840341567993},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2693629860877991},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.24273478984832764},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.17295438051223755},{"id":"https://openalex.org/C509550671","wikidata":"https://www.wikidata.org/wiki/Q126945","display_name":"Medical education","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D000939","descriptor_name":"Epitopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000945","descriptor_name":"Antigens, Differentiation, T-Lymphocyte","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000954","descriptor_name":"Antigens, Surface","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000954","descriptor_name":"Antigens, Surface","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D000954","descriptor_name":"Antigens, Surface","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D001402","descriptor_name":"B-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D001667","descriptor_name":"Binding, Competitive","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002621","descriptor_name":"Chemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003602","descriptor_name":"Cytotoxicity, Immunologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011914","descriptor_name":"Rats, Inbred BN","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011951","descriptor_name":"Receptors, Complement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013602","descriptor_name":"T-Lymphocytes, Cytotoxic","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D013602","descriptor_name":"T-Lymphocytes, Cytotoxic","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055598","descriptor_name":"Chemical Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1111/j.1600-065x.1982.tb01064.x","doi":"https://doi.org/10.1111/j.1600-065x.1982.tb01064.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1600-065x.1982.tb01064.x","pdf_url":null,"source":{"id":"https://openalex.org/S133112385","display_name":"Immunological Reviews","issn_l":"0105-2896","issn":["0105-2896","1600-065X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunological Reviews","raw_type":"journal-article"},{"id":"pmid:6184305","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6184305","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunological reviews","raw_type":"Journal Article"},{"id":"pmh:oai:mouseion.jax.org:ssbb1982-1095","doi":null,"is_oa":false,"landing_page_url":"https://mouseion.jax.org/ssbb1982/96","pdf_url":null,"source":{"id":"https://openalex.org/S4377196421","display_name":"The Mouseion at the JAXlibrary (Jackson Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210115256","host_organization_name":"Jackson Laboratory","host_organization_lineage":["https://openalex.org/I4210115256"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Subject Strain Bibliography 1982","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.504800021648407,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":55,"referenced_works":["https://openalex.org/W4163807","https://openalex.org/W32073311","https://openalex.org/W40843633","https://openalex.org/W95632070","https://openalex.org/W98709666","https://openalex.org/W109316051","https://openalex.org/W202444208","https://openalex.org/W1484731058","https://openalex.org/W1494564256","https://openalex.org/W1498099821","https://openalex.org/W1522215871","https://openalex.org/W1528682116","https://openalex.org/W1535636025","https://openalex.org/W1547573787","https://openalex.org/W1585833237","https://openalex.org/W1594111463","https://openalex.org/W1612135387","https://openalex.org/W1619709297","https://openalex.org/W1659855818","https://openalex.org/W1725113599","https://openalex.org/W1865777146","https://openalex.org/W1869087861","https://openalex.org/W1967597089","https://openalex.org/W1970654518","https://openalex.org/W1975544512","https://openalex.org/W1983520984","https://openalex.org/W1994888630","https://openalex.org/W2018932922","https://openalex.org/W2023318533","https://openalex.org/W2028396939","https://openalex.org/W2047506077","https://openalex.org/W2050567291","https://openalex.org/W2055967995","https://openalex.org/W2059869329","https://openalex.org/W2066949713","https://openalex.org/W2070437307","https://openalex.org/W2080332747","https://openalex.org/W2087655494","https://openalex.org/W2094228017","https://openalex.org/W2105074038","https://openalex.org/W2139203324","https://openalex.org/W2141906846","https://openalex.org/W2142488029","https://openalex.org/W2149814404","https://openalex.org/W2150507663","https://openalex.org/W2158055057","https://openalex.org/W2161304120","https://openalex.org/W2310464721","https://openalex.org/W2313595154","https://openalex.org/W2338012465","https://openalex.org/W2369126530","https://openalex.org/W2411023727","https://openalex.org/W2421826808","https://openalex.org/W4313310667","https://openalex.org/W4321835822"],"related_works":["https://openalex.org/W7096297604","https://openalex.org/W1585833237","https://openalex.org/W2140799426","https://openalex.org/W2073648990","https://openalex.org/W2087655494","https://openalex.org/W1970654518","https://openalex.org/W134119890","https://openalex.org/W2286621464","https://openalex.org/W2891765502","https://openalex.org/W7057851284"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
