{"id":"https://openalex.org/W2089933763","doi":"https://doi.org/10.1016/s0016-5085(98)70540-2","title":"Brain-gut axis in health and disease","display_name":"Brain-gut axis in health and disease","publication_year":1998,"publication_date":"1998-03-01","ids":{"openalex":"https://openalex.org/W2089933763","doi":"https://doi.org/10.1016/s0016-5085(98)70540-2","mag":"2089933763","pmid":"https://pubmed.ncbi.nlm.nih.gov/9496948"},"language":"en","primary_location":{"id":"doi:10.1016/s0016-5085(98)70540-2","doi":"https://doi.org/10.1016/s0016-5085(98)70540-2","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0016-5085(98)70540-2","pdf_url":"http://www.gastrojournal.org/article/S0016508598705402/pdf","source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2089933763"],"child_works_count":0,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.gastrojournal.org/article/S0016508598705402/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054250912","display_name":"Qasim Aziz","orcid":"https://orcid.org/0000-0002-2718-2065","observed_orcids":["https://orcid.org/0000-0002-2718-2065"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Qasim Aziz","raw_affiliation_strings":["Department of Medicine, Section of Gastroenterology, University of Manchester, England","Department of Medicine, Section of Gastroenterology, University of Manchester, Manchester, England"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Section of Gastroenterology, University of Manchester, England","institution_ids":["https://openalex.org/I28407311"]},{"raw_affiliation_string":"Department of Medicine, Section of Gastroenterology, University of Manchester, Manchester, England","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110421054","display_name":"David G. Thompson","orcid":"https://orcid.org/0000-0001-8518-6307","observed_orcids":["https://orcid.org/0000-0001-8518-6307"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"David G. Thompson","raw_affiliation_strings":["Department of Medicine, Section of Gastroenterology, University of Manchester, Manchester, England"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Section of Gastroenterology, University of Manchester, Manchester, England","institution_ids":["https://openalex.org/I28407311"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I28407311"],"apc_list":{"value":4180,"currency":"USD","value_usd":4180},"apc_paid":null,"fwci":3.6399,"has_fulltext":false,"cited_by_count":332,"citation_normalized_percentile":{"value":0.97297297,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"114","issue":"3","first_page":"559","last_page":"578"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.9682999849319458,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.9682999849319458,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.020999999716877937,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gut-brain-axis","display_name":"gut-brain axis","score":0.9940000176429749},{"id":"https://openalex.org/keywords/neurogastroenterology","display_name":"neurogastroenterology","score":0.7710000276565552},{"id":"https://openalex.org/keywords/gastrointestinal-diseases","display_name":"gastrointestinal diseases","score":0.5289999842643738}],"concepts":[{"id":"https://openalex.org/C2991673738","wikidata":"https://www.wikidata.org/wiki/Q5062122","display_name":"Brain disease","level":3,"score":0.6020627021789551},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.48606541752815247},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.48121169209480286},{"id":"https://openalex.org/C177857423","wikidata":"https://www.wikidata.org/wiki/Q17077315","display_name":"Gut\u2013brain axis","level":3,"score":0.47218456864356995},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.37256741523742676},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.32703539729118347}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D004947","descriptor_name":"Esophagus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005071","descriptor_name":"Evoked Potentials","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007422","descriptor_name":"Intestines","qualifier_ui":"Q000294","qualifier_name":"innervation","is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014055","descriptor_name":"Tomography, Emission-Computed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015225","descriptor_name":"Magnetoencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0016-5085(98)70540-2","doi":"https://doi.org/10.1016/s0016-5085(98)70540-2","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0016-5085(98)70540-2","pdf_url":"http://www.gastrojournal.org/article/S0016508598705402/pdf","source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"},{"id":"pmid:9496948","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9496948","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/s0016-5085(98)70540-2","doi":"https://doi.org/10.1016/s0016-5085(98)70540-2","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0016-5085(98)70540-2","pdf_url":"http://www.gastrojournal.org/article/S0016508598705402/pdf","source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":169,"referenced_works":["https://openalex.org/W5194732","https://openalex.org/W14068713","https://openalex.org/W16087538","https://openalex.org/W45484352","https://openalex.org/W66812637","https://openalex.org/W82843477","https://openalex.org/W92330165","https://openalex.org/W101703876","https://openalex.org/W114960545","https://openalex.org/W146652820","https://openalex.org/W173988102","https://openalex.org/W587431212","https://openalex.org/W599302072","https://openalex.org/W612866927","https://openalex.org/W630010072","https://openalex.org/W649615004","https://openalex.org/W1159565557","https://openalex.org/W1413158895","https://openalex.org/W1489316397","https://openalex.org/W1492317828","https://openalex.org/W1530290817","https://openalex.org/W1538404645","https://openalex.org/W1538916083","https://openalex.org/W1577372936","https://openalex.org/W1593113184","https://openalex.org/W1594846728","https://openalex.org/W1614249399","https://openalex.org/W1655949536","https://openalex.org/W1681077842","https://openalex.org/W1785565621","https://openalex.org/W1848354815","https://openalex.org/W1866253122","https://openalex.org/W1873448316","https://openalex.org/W1887859606","https://openalex.org/W1897644917","https://openalex.org/W1910413717","https://openalex.org/W1927832597","https://openalex.org/W1938313559","https://openalex.org/W1965044361","https://openalex.org/W1966343066","https://openalex.org/W1968280685","https://openalex.org/W1968869699","https://openalex.org/W1973476407","https://openalex.org/W1976310333","https://openalex.org/W1976430391","https://openalex.org/W1977439604","https://openalex.org/W1978274717","https://openalex.org/W1978331457","https://openalex.org/W1979177881","https://openalex.org/W1984702338","https://openalex.org/W1992103194","https://openalex.org/W1993916834","https://openalex.org/W1995723518","https://openalex.org/W1996451341","https://openalex.org/W1996529647","https://openalex.org/W1996826305","https://openalex.org/W1996914019","https://openalex.org/W1997440138","https://openalex.org/W2001700174","https://openalex.org/W2001713951","https://openalex.org/W2002439500","https://openalex.org/W2003584740","https://openalex.org/W2004185138","https://openalex.org/W2006917026","https://openalex.org/W2008473424","https://openalex.org/W2008905621","https://openalex.org/W2009805742","https://openalex.org/W2009855911","https://openalex.org/W2011262963","https://openalex.org/W2013930024","https://openalex.org/W2014493574","https://openalex.org/W2019320808","https://openalex.org/W2020473004","https://openalex.org/W2021743876","https://openalex.org/W2024331911","https://openalex.org/W2024999919","https://openalex.org/W2026204132","https://openalex.org/W2026468472","https://openalex.org/W2026810249","https://openalex.org/W2027865952","https://openalex.org/W2028001924","https://openalex.org/W2028899093","https://openalex.org/W2033742672","https://openalex.org/W2034135634","https://openalex.org/W2037543907","https://openalex.org/W2038769492","https://openalex.org/W2041027608","https://openalex.org/W2044002620","https://openalex.org/W2044162448","https://openalex.org/W2046400707","https://openalex.org/W2046648549","https://openalex.org/W2048326499","https://openalex.org/W2050329450","https://openalex.org/W2051992457","https://openalex.org/W2052816486","https://openalex.org/W2054812899","https://openalex.org/W2059500422","https://openalex.org/W2059804477","https://openalex.org/W2060707121","https://openalex.org/W2062679701","https://openalex.org/W2065624298","https://openalex.org/W2070059132","https://openalex.org/W2072337311","https://openalex.org/W2072657328","https://openalex.org/W2073887973","https://openalex.org/W2074716497","https://openalex.org/W2076033631","https://openalex.org/W2079254820","https://openalex.org/W2080168562","https://openalex.org/W2080776366","https://openalex.org/W2080961598","https://openalex.org/W2089561751","https://openalex.org/W2090671297","https://openalex.org/W2094376138","https://openalex.org/W2094542138","https://openalex.org/W2105145294","https://openalex.org/W2108117677","https://openalex.org/W2108476002","https://openalex.org/W2113077656","https://openalex.org/W2125408150","https://openalex.org/W2131695842","https://openalex.org/W2146738981","https://openalex.org/W2153282831","https://openalex.org/W2157961804","https://openalex.org/W2158102168","https://openalex.org/W2166445016","https://openalex.org/W2177901546","https://openalex.org/W2277451297","https://openalex.org/W2297247407","https://openalex.org/W2312729008","https://openalex.org/W2317498913","https://openalex.org/W2336695323","https://openalex.org/W2337545080","https://openalex.org/W2337677501","https://openalex.org/W2340904182","https://openalex.org/W2398043197","https://openalex.org/W2403170949","https://openalex.org/W2411606357","https://openalex.org/W2412070803","https://openalex.org/W2412560454","https://openalex.org/W2412624866","https://openalex.org/W2415789041","https://openalex.org/W2416465245","https://openalex.org/W2418108084","https://openalex.org/W2482349651","https://openalex.org/W2493705186","https://openalex.org/W2496301122","https://openalex.org/W2556719987","https://openalex.org/W2568391015","https://openalex.org/W2737643079","https://openalex.org/W2941103581","https://openalex.org/W3004295826","https://openalex.org/W3049051495","https://openalex.org/W3049373093","https://openalex.org/W3049503959","https://openalex.org/W3049563746","https://openalex.org/W3137861108","https://openalex.org/W3141417327","https://openalex.org/W4255492990","https://openalex.org/W4285719527","https://openalex.org/W4388248982","https://openalex.org/W4388249745","https://openalex.org/W4388249865","https://openalex.org/W4408148145","https://openalex.org/W6659707857","https://openalex.org/W6781847965","https://openalex.org/W6781931866","https://openalex.org/W6782201680","https://openalex.org/W6782343398"],"related_works":["https://openalex.org/W801284118","https://openalex.org/W7128552581","https://openalex.org/W4384156115","https://openalex.org/W4404822574","https://openalex.org/W4256281652","https://openalex.org/W7213254317","https://openalex.org/W4413325438","https://openalex.org/W4366988013","https://openalex.org/W4301648502","https://openalex.org/W2893488006"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":12},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":13},{"year":2018,"cited_by_count":13},{"year":2017,"cited_by_count":14},{"year":2016,"cited_by_count":11},{"year":2015,"cited_by_count":17},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":8},{"year":2012,"cited_by_count":11}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}