{"id":"https://openalex.org/W2089801546","doi":"https://doi.org/10.1093/jac/29.suppl_a.13","title":"Antibacterial activity in vitro of cefpirome against clinical isolates causing sexually transmitted diseases","display_name":"Antibacterial activity in vitro of cefpirome against clinical isolates causing sexually transmitted diseases","publication_year":1992,"publication_date":"1992-01-01","ids":{"openalex":"https://openalex.org/W2089801546","doi":"https://doi.org/10.1093/jac/29.suppl_a.13","mag":"2089801546","pmid":"https://pubmed.ncbi.nlm.nih.gov/1318294"},"language":"en","primary_location":{"id":"doi:10.1093/jac/29.suppl_a.13","doi":"https://doi.org/10.1093/jac/29.suppl_a.13","is_oa":false,"landing_page_url":"https://doi.org/10.1093/jac/29.suppl_a.13","pdf_url":null,"source":{"id":"https://openalex.org/S124275759","display_name":"Journal of Antimicrobial Chemotherapy","issn_l":"0305-7453","issn":["0305-7453","1460-2091"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Antimicrobial Chemotherapy","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086366346","display_name":"Michael Limbert","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. Limbert","raw_affiliation_strings":["Hoechst AG, SBU Anti-infectives Research, Frankfurt, Germany","Hoechst AG, SBU Anti-infectives ResearchPostfach 800320. 6230 Frankfurt/M., Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hoechst AG, SBU Anti-infectives Research, Frankfurt, Germany","institution_ids":[]},{"raw_affiliation_string":"Hoechst AG, SBU Anti-infectives ResearchPostfach 800320. 6230 Frankfurt/M., Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"G. Seibert","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G. Seibert","raw_affiliation_strings":["Hoechst AG, SBU Anti-infectives ResearchPostfach 800320. 6230 Frankfurt/M., Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hoechst AG, SBU Anti-infectives ResearchPostfach 800320. 6230 Frankfurt/M., Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108771783","display_name":"Irvin Winkler","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"I. Winkler","raw_affiliation_strings":["Hoechst AG, SBU Anti-infectives ResearchPostfach 800320. 6230 Frankfurt/M., Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hoechst AG, SBU Anti-infectives ResearchPostfach 800320. 6230 Frankfurt/M., Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077654957","display_name":"DIETER ISERT","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D. Isert","raw_affiliation_strings":["Hoechst AG, SBU Anti-infectives ResearchPostfach 800320. 6230 Frankfurt/M., Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hoechst AG, SBU Anti-infectives ResearchPostfach 800320. 6230 Frankfurt/M., Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036554952","display_name":"NORBERT KLESEL","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N. Klesel","raw_affiliation_strings":["Hoechst AG, SBU Anti-infectives ResearchPostfach 800320. 6230 Frankfurt/M., Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hoechst AG, SBU Anti-infectives ResearchPostfach 800320. 6230 Frankfurt/M., Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112995371","display_name":"A. Markus","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A. Markus","raw_affiliation_strings":["Hoechst AG, SBU Anti-infectives ResearchPostfach 800320. 6230 Frankfurt/M., Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hoechst AG, SBU Anti-infectives ResearchPostfach 800320. 6230 Frankfurt/M., Germany","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5067742563","display_name":"E. Schrinner","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E. Schrinner","raw_affiliation_strings":["Hoechst AG, SBU Anti-infectives ResearchPostfach 800320. 6230 Frankfurt/M., Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hoechst AG, SBU Anti-infectives ResearchPostfach 800320. 6230 Frankfurt/M., Germany","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2869,"currency":"GBP","value_usd":3784},"apc_paid":null,"fwci":0.5766,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.65017585,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"29","issue":"suppl A","first_page":"13","last_page":"17"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10428","display_name":"Reproductive tract infections research","score":0.9023000001907349,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10428","display_name":"Reproductive tract infections research","score":0.9023000001907349,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11036","display_name":"Antibiotics Pharmacokinetics and Efficacy","score":0.03530000150203705,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.01889999955892563,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cefpirome","display_name":"cefpirome","score":1.0},{"id":"https://openalex.org/keywords/sexually-transmitted-infections","display_name":"sexually transmitted infections","score":0.8539999723434448},{"id":"https://openalex.org/keywords/neisseria-gonorrhoeae","display_name":"Neisseria gonorrhoeae","score":0.9929999709129333},{"id":"https://openalex.org/keywords/haemophilus-ducreyi","display_name":"Haemophilus ducreyi","score":1.0},{"id":"https://openalex.org/keywords/gardnerella-vaginalis","display_name":"Gardnerella vaginalis","score":1.0},{"id":"https://openalex.org/keywords/in-vitro-antibacterial-activity","display_name":"in vitro antibacterial activity","score":0.7580000162124634},{"id":"https://openalex.org/keywords/minimum-inhibitory-concentration","display_name":"minimum inhibitory concentration","score":0.824999988079071},{"id":"https://openalex.org/keywords/empirical-treatment","display_name":"empirical treatment","score":0.7350000143051147},{"id":"https://openalex.org/keywords/cephalosporins","display_name":"cephalosporins","score":0.9190000295639038}],"concepts":[{"id":"https://openalex.org/C2777457247","wikidata":"https://www.wikidata.org/wiki/Q2943814","display_name":"Cefpirome","level":5,"score":0.8895984888076782},{"id":"https://openalex.org/C2779166590","wikidata":"https://www.wikidata.org/wiki/Q131129","display_name":"Neisseria gonorrhoeae","level":2,"score":0.8634207248687744},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.7133668661117554},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.6031208038330078},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.5648728609085083},{"id":"https://openalex.org/C2780018483","wikidata":"https://www.wikidata.org/wiki/Q127375","display_name":"Gardnerella vaginalis","level":3,"score":0.47582390904426575},{"id":"https://openalex.org/C2909760446","wikidata":"https://www.wikidata.org/wiki/Q12198","display_name":"Sexually transmitted disease","level":4,"score":0.44756993651390076},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.40872910618782043},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3542157709598541},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.33602648973464966},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.2191365659236908},{"id":"https://openalex.org/C94665300","wikidata":"https://www.wikidata.org/wiki/Q63391344","display_name":"Antibiotic resistance","level":3,"score":0.132582426071167},{"id":"https://openalex.org/C2779952448","wikidata":"https://www.wikidata.org/wiki/Q804521","display_name":"Bacterial vaginosis","level":2,"score":0.12077522277832031},{"id":"https://openalex.org/C2776983459","wikidata":"https://www.wikidata.org/wiki/Q41083","display_name":"Syphilis","level":3,"score":0.08818954229354858},{"id":"https://openalex.org/C2779631663","wikidata":"https://www.wikidata.org/wiki/Q425152","display_name":"Imipenem","level":4,"score":0.04676234722137451},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000097572","descriptor_name":"Cefpirome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002511","descriptor_name":"Cephalosporins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D002602","descriptor_name":"Chancroid","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D002689","descriptor_name":"Chlamydia","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002690","descriptor_name":"Chlamydia Infections","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D006069","descriptor_name":"Gonorrhea","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D006191","descriptor_name":"Haemophilus ducreyi","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006194","descriptor_name":"Gardnerella vaginalis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008826","descriptor_name":"Microbial Sensitivity Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009344","descriptor_name":"Neisseria gonorrhoeae","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D010406","descriptor_name":"Penicillins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D015231","descriptor_name":"Sexually Transmitted Diseases, Bacterial","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D015363","descriptor_name":"Quinolones","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/jac/29.suppl_a.13","doi":"https://doi.org/10.1093/jac/29.suppl_a.13","is_oa":false,"landing_page_url":"https://doi.org/10.1093/jac/29.suppl_a.13","pdf_url":null,"source":{"id":"https://openalex.org/S124275759","display_name":"Journal of Antimicrobial Chemotherapy","issn_l":"0305-7453","issn":["0305-7453","1460-2091"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Antimicrobial Chemotherapy","raw_type":"journal-article"},{"id":"pmid:1318294","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1318294","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of antimicrobial chemotherapy","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2409972304","https://openalex.org/W2102424891","https://openalex.org/W2464730939","https://openalex.org/W190892196","https://openalex.org/W2112557085","https://openalex.org/W2051976492","https://openalex.org/W280596825","https://openalex.org/W1563545374","https://openalex.org/W261970954","https://openalex.org/W46597526"],"abstract_inverted_index":{"The":[0,17],"in-vitro":[1],"activity":[2,19],"of":[3,20,50,53],"cefpirome":[4,21],"was":[5],"compared":[6],"with":[7],"other":[8],"antibiotics":[9],"against":[10,22],"organisms":[11],"causing":[12],"sexually":[13],"transmitted":[14],"diseases":[15],"(STD).":[16],"excellent":[18],"Neisseria":[23],"gonorrhoeae":[24],"(MIC90":[25,30,36],"1.0":[26,37],"mg/L),":[27,32],"Haemophilus":[28],"ducreyi":[29],"0.5":[31],"and":[33],"Gardnerella":[34],"vaginalis":[35],"mg/L)":[38],"suggests":[39],"that":[40],"this":[41],"agent":[42],"might":[43],"be":[44],"useful":[45],"in":[46],"the":[47],"empirical":[48],"treatment":[49],"a":[51],"variety":[52],"venereal":[54],"diseases.":[55]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}