{"id":"https://openalex.org/W2089626640","doi":"https://doi.org/10.1038/nbt.1678","title":"Epigenetic modifications as therapeutic targets","display_name":"Epigenetic modifications as therapeutic targets","publication_year":2010,"publication_date":"2010-10-01","ids":{"openalex":"https://openalex.org/W2089626640","doi":"https://doi.org/10.1038/nbt.1678","mag":"2089626640","pmid":"https://pubmed.ncbi.nlm.nih.gov/20944599","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3022972"},"language":"en","primary_location":{"id":"doi:10.1038/nbt.1678","doi":"https://doi.org/10.1038/nbt.1678","is_oa":false,"landing_page_url":"https://doi.org/10.1038/nbt.1678","pdf_url":null,"source":{"id":"https://openalex.org/S106963461","display_name":"Nature Biotechnology","issn_l":"0733-222X","issn":["0733-222X","1087-0156","1546-1696","2331-3684"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Biotechnology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3022972","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110559476","display_name":"Theresa Kathleen Kelly","orcid":"https://orcid.org/0000-0001-8845-8777","observed_orcids":["https://orcid.org/0000-0001-8845-8777"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I4210117038","display_name":"USC Norris Comprehensive Cancer Center","ror":"https://ror.org/01nmyfr60","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800154431","https://openalex.org/I4210117038"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Theresa K Kelly","raw_affiliation_strings":["Departments of Urology and Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, USA","Departments of Urology and Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Urology and Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, USA","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I4210117038"]},{"raw_affiliation_string":"Departments of Urology and Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, USA","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I4210117038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069130022","display_name":"Daniel Diniz De Carvalho","orcid":"https://orcid.org/0000-0002-8572-5259","observed_orcids":["https://orcid.org/0000-0002-8572-5259","https://orcid.org/0000-0003-0771-2265"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I4210117038","display_name":"USC Norris Comprehensive Cancer Center","ror":"https://ror.org/01nmyfr60","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800154431","https://openalex.org/I4210117038"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel D De Carvalho","raw_affiliation_strings":["Departments of Urology and Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, USA","Departments of Urology and Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Urology and Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, USA","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I4210117038"]},{"raw_affiliation_string":"Departments of Urology and Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, USA","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I4210117038"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088347458","display_name":"Peter A. Jones","orcid":"https://orcid.org/0000-0001-8309-4767","observed_orcids":["https://orcid.org/0000-0001-8309-4767"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I4210117038","display_name":"USC Norris Comprehensive Cancer Center","ror":"https://ror.org/01nmyfr60","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800154431","https://openalex.org/I4210117038"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Peter A Jones","raw_affiliation_strings":["Departments of Urology and Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, USA","Departments of Urology and Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Urology and Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, USA","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I4210117038"]},{"raw_affiliation_string":"Departments of Urology and Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, USA","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I4210117038"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5088347458"],"corresponding_institution_ids":["https://openalex.org/I1174212","https://openalex.org/I4210117038"],"apc_list":{"value":12690,"currency":"USD","value_usd":12690},"apc_paid":null,"fwci":5.7513,"has_fulltext":false,"cited_by_count":800,"citation_normalized_percentile":{"value":0.98369188,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"28","issue":"10","first_page":"1069","last_page":"1078"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11736","display_name":"Histone Deacetylase Inhibitors Research","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/epigenetic-modifications","display_name":"epigenetic modifications","score":0.9610000252723694},{"id":"https://openalex.org/keywords/epigenetic-therapy","display_name":"epigenetic therapy","score":0.9559999704360962},{"id":"https://openalex.org/keywords/histone-deacetylase-inhibitors","display_name":"histone deacetylase inhibitors","score":0.9160000085830688},{"id":"https://openalex.org/keywords/dna-methylation-inhibitors","display_name":"DNA methylation inhibitors","score":0.9520000219345093},{"id":"https://openalex.org/keywords/histone-methylation","display_name":"histone methylation","score":0.9779999852180481},{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":0.9129999876022339},{"id":"https://openalex.org/keywords/hematologic-malignancies","display_name":"hematologic malignancies","score":0.968999981880188},{"id":"https://openalex.org/keywords/tumor-resistance","display_name":"tumor resistance","score":0.48100000619888306},{"id":"https://openalex.org/keywords/combination-therapy","display_name":"combination therapy","score":0.6890000104904175},{"id":"https://openalex.org/keywords/epigenetic-biomarkers","display_name":"epigenetic biomarkers","score":0.6930000185966492},{"id":"https://openalex.org/keywords/histone-acetylation","display_name":"histone acetylation","score":0.5960000157356262}],"concepts":[{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.9401971697807312},{"id":"https://openalex.org/C64927066","wikidata":"https://www.wikidata.org/wiki/Q36293","display_name":"Histone","level":3,"score":0.7238431572914124},{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.67369544506073},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6688361167907715},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.6171498894691467},{"id":"https://openalex.org/C2780737395","wikidata":"https://www.wikidata.org/wiki/Q18353741","display_name":"Epigenetic therapy","level":5,"score":0.5469803810119629},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5001637935638428},{"id":"https://openalex.org/C114691636","wikidata":"https://www.wikidata.org/wiki/Q5031434","display_name":"Cancer epigenetics","level":5,"score":0.45570477843284607},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4141431748867035},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.40783703327178955},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3229287266731262},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2609226405620575},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.21841320395469666},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.21603301167488098},{"id":"https://openalex.org/C150425827","wikidata":"https://www.wikidata.org/wiki/Q2560317","display_name":"Histone methyltransferase","level":4,"score":0.20035624504089355},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.19130688905715942},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.10922327637672424}],"mesh":[{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D006657","descriptor_name":"Histones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D009705","descriptor_name":"Nucleosides","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D044127","descriptor_name":"Epigenesis, Genetic","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D056572","descriptor_name":"Histone Deacetylase Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1038/nbt.1678","doi":"https://doi.org/10.1038/nbt.1678","is_oa":false,"landing_page_url":"https://doi.org/10.1038/nbt.1678","pdf_url":null,"source":{"id":"https://openalex.org/S106963461","display_name":"Nature Biotechnology","issn_l":"0733-222X","issn":["0733-222X","1087-0156","1546-1696","2331-3684"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Biotechnology","raw_type":"journal-article"},{"id":"pmid:20944599","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20944599","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature biotechnology","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:2320715","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3022972","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3022972","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3022972","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Nat Biotechnol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2320715","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3022972","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9907000064849854}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4307531130","display_name":"DNA METHYLATION IN DEVELOPMENT AND CANCER","funder_award_id":"R35CA049758","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G8730023577","display_name":"De Novo DNA Methylation in Bladder Cancer","funder_award_id":"R01CA083867","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G994689508","display_name":"Mechanisms of De Novo Methylation in Cancer","funder_award_id":"R37CA082422","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":120,"referenced_works":["https://openalex.org/W1484293540","https://openalex.org/W1506631602","https://openalex.org/W1533153036","https://openalex.org/W1963631769","https://openalex.org/W1964792512","https://openalex.org/W1966010937","https://openalex.org/W1966083128","https://openalex.org/W1969670934","https://openalex.org/W1970772467","https://openalex.org/W1972846893","https://openalex.org/W1972931349","https://openalex.org/W1978660434","https://openalex.org/W1980192737","https://openalex.org/W1985444222","https://openalex.org/W1987148763","https://openalex.org/W1989696433","https://openalex.org/W1993106716","https://openalex.org/W1996676239","https://openalex.org/W1997751561","https://openalex.org/W2002826921","https://openalex.org/W2002995168","https://openalex.org/W2004172747","https://openalex.org/W2004800182","https://openalex.org/W2006797972","https://openalex.org/W2007283154","https://openalex.org/W2008945738","https://openalex.org/W2009121506","https://openalex.org/W2009826707","https://openalex.org/W2013624745","https://openalex.org/W2015835690","https://openalex.org/W2017829956","https://openalex.org/W2025220605","https://openalex.org/W2025446192","https://openalex.org/W2027873015","https://openalex.org/W2028948821","https://openalex.org/W2029595590","https://openalex.org/W2029868343","https://openalex.org/W2033027341","https://openalex.org/W2033126020","https://openalex.org/W2034160841","https://openalex.org/W2035021866","https://openalex.org/W2037548653","https://openalex.org/W2040182688","https://openalex.org/W2040365591","https://openalex.org/W2041263849","https://openalex.org/W2042012963","https://openalex.org/W2042087070","https://openalex.org/W2042720616","https://openalex.org/W2045293701","https://openalex.org/W2052609775","https://openalex.org/W2053591294","https://openalex.org/W2054407912","https://openalex.org/W2054621094","https://openalex.org/W2059059097","https://openalex.org/W2059099579","https://openalex.org/W2061578142","https://openalex.org/W2063333928","https://openalex.org/W2070433411","https://openalex.org/W2072709919","https://openalex.org/W2079298594","https://openalex.org/W2081614272","https://openalex.org/W2084160423","https://openalex.org/W2084164320","https://openalex.org/W2085667285","https://openalex.org/W2086180957","https://openalex.org/W2090257623","https://openalex.org/W2090760765","https://openalex.org/W2096330673","https://openalex.org/W2098545729","https://openalex.org/W2099166288","https://openalex.org/W2101127235","https://openalex.org/W2101491950","https://openalex.org/W2102650381","https://openalex.org/W2103177465","https://openalex.org/W2103213382","https://openalex.org/W2105528101","https://openalex.org/W2106437700","https://openalex.org/W2108664872","https://openalex.org/W2109428091","https://openalex.org/W2112004353","https://openalex.org/W2112856354","https://openalex.org/W2113634596","https://openalex.org/W2114452590","https://openalex.org/W2116739152","https://openalex.org/W2117996813","https://openalex.org/W2118771330","https://openalex.org/W2119478924","https://openalex.org/W2120450507","https://openalex.org/W2125496315","https://openalex.org/W2128146359","https://openalex.org/W2128919238","https://openalex.org/W2132037667","https://openalex.org/W2133124834","https://openalex.org/W2135619784","https://openalex.org/W2135812015","https://openalex.org/W2136943826","https://openalex.org/W2138896702","https://openalex.org/W2139088310","https://openalex.org/W2141410747","https://openalex.org/W2142108003","https://openalex.org/W2146259423","https://openalex.org/W2148521032","https://openalex.org/W2149071620","https://openalex.org/W2150136461","https://openalex.org/W2152333235","https://openalex.org/W2153289239","https://openalex.org/W2156874253","https://openalex.org/W2157429725","https://openalex.org/W2159807040","https://openalex.org/W2160998038","https://openalex.org/W2162877470","https://openalex.org/W2164052369","https://openalex.org/W2168473428","https://openalex.org/W2169409181","https://openalex.org/W2169637209","https://openalex.org/W2170210082","https://openalex.org/W2171685419","https://openalex.org/W2317234826","https://openalex.org/W4230705206","https://openalex.org/W7074083545"],"related_works":["https://openalex.org/W2317649724","https://openalex.org/W7123830043","https://openalex.org/W2184537762","https://openalex.org/W2015287103","https://openalex.org/W2759946119","https://openalex.org/W2162841642","https://openalex.org/W2736022135","https://openalex.org/W3082906945","https://openalex.org/W2995898384","https://openalex.org/W2061560061"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":28},{"year":2025,"cited_by_count":40},{"year":2024,"cited_by_count":37},{"year":2023,"cited_by_count":37},{"year":2022,"cited_by_count":35},{"year":2021,"cited_by_count":37},{"year":2020,"cited_by_count":48},{"year":2019,"cited_by_count":56},{"year":2018,"cited_by_count":50},{"year":2017,"cited_by_count":59},{"year":2016,"cited_by_count":51},{"year":2015,"cited_by_count":54},{"year":2014,"cited_by_count":62},{"year":2013,"cited_by_count":66},{"year":2012,"cited_by_count":83}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}
