{"id":"https://openalex.org/W2089391807","doi":"https://doi.org/10.4161/cc.9.19.13467","title":"Differential basal levels ofMDM-2transcription induced by p53-P72 and p53-R72","display_name":"Differential basal levels ofMDM-2transcription induced by p53-P72 and p53-R72","publication_year":2010,"publication_date":"2010-10-01","ids":{"openalex":"https://openalex.org/W2089391807","doi":"https://doi.org/10.4161/cc.9.19.13467","mag":"2089391807","pmid":"https://pubmed.ncbi.nlm.nih.gov/20948295"},"language":"en","primary_location":{"id":"doi:10.4161/cc.9.19.13467","doi":"https://doi.org/10.4161/cc.9.19.13467","is_oa":true,"landing_page_url":"https://doi.org/10.4161/cc.9.19.13467","pdf_url":"https://www.tandfonline.com/doi/pdf/10.4161/cc.9.19.13467?needAccess=true&role=button","source":{"id":"https://openalex.org/S86011449","display_name":"Cell Cycle","issn_l":"1551-4005","issn":["1551-4005","1538-4101"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","medline","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Cycle","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.tandfonline.com/doi/pdf/10.4161/cc.9.19.13467?needAccess=true&role=button","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5029184162","display_name":"Kristina Heyne","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I91712215","display_name":"Saarland University","ror":"https://ror.org/01jdpyv68","country_code":"DE","type":"education","lineage":["https://openalex.org/I91712215"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Kristina Heyne","raw_affiliation_strings":["University of Saarland Medical School ; homburg (Saar) , Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Saarland Medical School ; homburg (Saar) , Germany","institution_ids":["https://openalex.org/I91712215"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Marcel Conrad","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I91712215","display_name":"Saarland University","ror":"https://ror.org/01jdpyv68","country_code":"DE","type":"education","lineage":["https://openalex.org/I91712215"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Marcel Conrad","raw_affiliation_strings":["University of Saarland Medical School ; homburg (Saar) , Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Saarland Medical School ; homburg (Saar) , Germany","institution_ids":["https://openalex.org/I91712215"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Daniela Dohmen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I91712215","display_name":"Saarland University","ror":"https://ror.org/01jdpyv68","country_code":"DE","type":"education","lineage":["https://openalex.org/I91712215"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Daniela Dohmen","raw_affiliation_strings":["University of Saarland Medical School ; homburg (Saar) , Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Saarland Medical School ; homburg (Saar) , Germany","institution_ids":["https://openalex.org/I91712215"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090897626","display_name":"Judith Huwer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Judith Huwer","raw_affiliation_strings":["Jos\u00e9 Carreras research Center ; internal Medicine i ;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jos\u00e9 Carreras research Center ; internal Medicine i ;","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043709743","display_name":"Gunter Assmann","orcid":"https://orcid.org/0000-0002-3216-9340","observed_orcids":["https://orcid.org/0000-0002-3216-9340"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gunter Assmann","raw_affiliation_strings":["Jos\u00e9 Carreras research Center ; internal Medicine i ;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jos\u00e9 Carreras research Center ; internal Medicine i ;","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110025668","display_name":"Klaus Roemer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I91712215","display_name":"Saarland University","ror":"https://ror.org/01jdpyv68","country_code":"DE","type":"education","lineage":["https://openalex.org/I91712215"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Klaus Roemer","raw_affiliation_strings":["University of Saarland Medical School ; homburg (Saar) , Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Saarland Medical School ; homburg (Saar) , Germany","institution_ids":["https://openalex.org/I91712215"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5110025668"],"corresponding_institution_ids":["https://openalex.org/I91712215"],"apc_list":null,"apc_paid":null,"fwci":0.1622,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.54874968,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"9","issue":"19","first_page":"4028","last_page":"4030"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10583","display_name":"Cancer-related Molecular Pathways","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10583","display_name":"Cancer-related Molecular Pathways","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10934","display_name":"Heat shock proteins research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10294","display_name":"Cell death mechanisms and regulation","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mdm2","display_name":"MDM2","score":0.8360000252723694},{"id":"https://openalex.org/keywords/p53","display_name":"p53","score":0.8759999871253967},{"id":"https://openalex.org/keywords/transcriptional-regulation","display_name":"transcriptional regulation","score":0.5360000133514404},{"id":"https://openalex.org/keywords/basal-transcription","display_name":"basal transcription","score":0.6499999761581421},{"id":"https://openalex.org/keywords/p53-isoforms","display_name":"p53 isoforms","score":0.6119999885559082},{"id":"https://openalex.org/keywords/tumor-suppressor-proteins","display_name":"tumor suppressor proteins","score":0.5619999766349792}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.948355495929718},{"id":"https://openalex.org/C2778024521","wikidata":"https://www.wikidata.org/wiki/Q55639806","display_name":"Basal (medicine)","level":3,"score":0.44069772958755493},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3718903660774231},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3633509874343872},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.1087653636932373},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D005347","descriptor_name":"Fibroblasts","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D005347","descriptor_name":"Fibroblasts","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016159","descriptor_name":"Tumor Suppressor Protein p53","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016159","descriptor_name":"Tumor Suppressor Protein p53","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051736","descriptor_name":"Proto-Oncogene Proteins c-mdm2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051736","descriptor_name":"Proto-Oncogene Proteins c-mdm2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.4161/cc.9.19.13467","doi":"https://doi.org/10.4161/cc.9.19.13467","is_oa":true,"landing_page_url":"https://doi.org/10.4161/cc.9.19.13467","pdf_url":"https://www.tandfonline.com/doi/pdf/10.4161/cc.9.19.13467?needAccess=true&role=button","source":{"id":"https://openalex.org/S86011449","display_name":"Cell Cycle","issn_l":"1551-4005","issn":["1551-4005","1538-4101"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","medline","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Cycle","raw_type":"journal-article"},{"id":"pmid:20948295","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20948295","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell cycle (Georgetown, Tex.)","raw_type":"Letter"}],"best_oa_location":{"id":"doi:10.4161/cc.9.19.13467","doi":"https://doi.org/10.4161/cc.9.19.13467","is_oa":true,"landing_page_url":"https://doi.org/10.4161/cc.9.19.13467","pdf_url":"https://www.tandfonline.com/doi/pdf/10.4161/cc.9.19.13467?needAccess=true&role=button","source":{"id":"https://openalex.org/S86011449","display_name":"Cell Cycle","issn_l":"1551-4005","issn":["1551-4005","1538-4101"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","medline","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Cycle","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6240000128746033}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2089391807.pdf","grobid_xml":"https://content.openalex.org/works/W2089391807.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1856511422","https://openalex.org/W2320656371","https://openalex.org/W1984948285","https://openalex.org/W2143405385","https://openalex.org/W1857008528","https://openalex.org/W3144766521","https://openalex.org/W2883445384","https://openalex.org/W7099900748","https://openalex.org/W2329143335","https://openalex.org/W1983660125"],"abstract_inverted_index":{"(2010).":[0],"Differential":[1],"basal":[2],"levels":[3],"of":[4],"MDM-2":[5],"transcription":[6],"induced":[7],"by":[8],"p53-P72":[9],"and":[10],"p53-R72.":[11],"Cell":[12],"Cycle:":[13],"Vol.":[14],"9,":[15],"No.":[16],"19,":[17],"pp.":[18],"4028-4030.":[19]},"counts_by_year":[],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}