{"id":"https://openalex.org/W2089294142","doi":"https://doi.org/10.4161/epi.21644","title":"Transgenerational maintenance of transgene body CG but not CHG and CHH methylation","display_name":"Transgenerational maintenance of transgene body CG but not CHG and CHH methylation","publication_year":2012,"publication_date":"2012-08-16","ids":{"openalex":"https://openalex.org/W2089294142","doi":"https://doi.org/10.4161/epi.21644","mag":"2089294142","pmid":"https://pubmed.ncbi.nlm.nih.gov/22863736","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3466191"},"language":"en","primary_location":{"id":"doi:10.4161/epi.21644","doi":"https://doi.org/10.4161/epi.21644","is_oa":true,"landing_page_url":"https://doi.org/10.4161/epi.21644","pdf_url":"https://www.tandfonline.com/doi/pdf/10.4161/epi.21644?needAccess=true&role=button","source":{"id":"https://openalex.org/S203437305","display_name":"Epigenetics","issn_l":"1559-2294","issn":["1559-2294","1559-2308"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315740","host_organization_name":"Landes Bioscience","host_organization_lineage":["https://openalex.org/P4310315740"],"host_organization_lineage_names":["Landes Bioscience"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epigenetics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.tandfonline.com/doi/pdf/10.4161/epi.21644?needAccess=true&role=button","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5059103410","display_name":"Athanasios Dalakouras","orcid":"https://orcid.org/0000-0002-4446-1808","observed_orcids":["https://orcid.org/0000-0002-4446-1808"]},"institutions":[{"id":"https://openalex.org/I4210142180","display_name":"RLP AgroScience (Germany)","ror":"https://ror.org/04j6cwd10","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210142180"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Athanasios Dalakouras","raw_affiliation_strings":["RLP AgroScience GmbH, AlPlanta-Institute for Plant Research, Neustadt, Germany","AlPlanta-Institute for Plant Research","Neustadt, Germany","RLP AgroScience GmbH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"RLP AgroScience GmbH, AlPlanta-Institute for Plant Research, Neustadt, Germany","institution_ids":["https://openalex.org/I4210142180"]},{"raw_affiliation_string":"AlPlanta-Institute for Plant Research","institution_ids":[]},{"raw_affiliation_string":"Neustadt, Germany","institution_ids":[]},{"raw_affiliation_string":"RLP AgroScience GmbH","institution_ids":["https://openalex.org/I4210142180"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024959608","display_name":"Elena Dadami","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210142180","display_name":"RLP AgroScience (Germany)","ror":"https://ror.org/04j6cwd10","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210142180"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Elena Dadami","raw_affiliation_strings":["RLP AgroScience GmbH; AlPlanta-Institute for Plant Research; Neustadt, Germany","AlPlanta-Institute for Plant Research","Neustadt, Germany","RLP AgroScience GmbH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"RLP AgroScience GmbH; AlPlanta-Institute for Plant Research; Neustadt, Germany","institution_ids":["https://openalex.org/I4210142180"]},{"raw_affiliation_string":"AlPlanta-Institute for Plant Research","institution_ids":[]},{"raw_affiliation_string":"Neustadt, Germany","institution_ids":[]},{"raw_affiliation_string":"RLP AgroScience GmbH","institution_ids":["https://openalex.org/I4210142180"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018609774","display_name":"Mich\u00e8le Zwiebel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210142180","display_name":"RLP AgroScience (Germany)","ror":"https://ror.org/04j6cwd10","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210142180"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Michele Zwiebel","raw_affiliation_strings":["RLP AgroScience GmbH; AlPlanta-Institute for Plant Research; Neustadt, Germany","AlPlanta-Institute for Plant Research","Neustadt, Germany","RLP AgroScience GmbH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"RLP AgroScience GmbH; AlPlanta-Institute for Plant Research; Neustadt, Germany","institution_ids":["https://openalex.org/I4210142180"]},{"raw_affiliation_string":"AlPlanta-Institute for Plant Research","institution_ids":[]},{"raw_affiliation_string":"Neustadt, Germany","institution_ids":[]},{"raw_affiliation_string":"RLP AgroScience GmbH","institution_ids":["https://openalex.org/I4210142180"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015807033","display_name":"Gabi Krczal","orcid":"https://orcid.org/0000-0003-2251-593X","observed_orcids":["https://orcid.org/0000-0003-2251-593X"]},"institutions":[{"id":"https://openalex.org/I4210142180","display_name":"RLP AgroScience (Germany)","ror":"https://ror.org/04j6cwd10","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210142180"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Gabi Krczal","raw_affiliation_strings":["RLP AgroScience GmbH; AlPlanta-Institute for Plant Research; Neustadt, Germany","AlPlanta-Institute for Plant Research","Neustadt, Germany","RLP AgroScience GmbH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"RLP AgroScience GmbH; AlPlanta-Institute for Plant Research; Neustadt, Germany","institution_ids":["https://openalex.org/I4210142180"]},{"raw_affiliation_string":"AlPlanta-Institute for Plant Research","institution_ids":[]},{"raw_affiliation_string":"Neustadt, Germany","institution_ids":[]},{"raw_affiliation_string":"RLP AgroScience GmbH","institution_ids":["https://openalex.org/I4210142180"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5066807390","display_name":"Michael Wassenegger","orcid":"https://orcid.org/0000-0002-7926-2454","observed_orcids":["https://orcid.org/0000-0002-7926-2454"]},"institutions":[{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]},{"id":"https://openalex.org/I4210142180","display_name":"RLP AgroScience (Germany)","ror":"https://ror.org/04j6cwd10","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210142180"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Michael Wassenegger","raw_affiliation_strings":["RLP AgroScience GmbH; AlPlanta-Institute for Plant Research; Neustadt, Germany; Centre for Organismal Studies (COS) Heidelberg; University of Heidelberg; Heidelberg, Germany","AlPlanta-Institute for Plant Research","Centre for Organismal Studies (COS) Heidelberg","Heidelberg, Germany","Neustadt, Germany","RLP AgroScience GmbH","University of Heidelberg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"RLP AgroScience GmbH; AlPlanta-Institute for Plant Research; Neustadt, Germany; Centre for Organismal Studies (COS) Heidelberg; University of Heidelberg; Heidelberg, Germany","institution_ids":["https://openalex.org/I223822909","https://openalex.org/I4210142180"]},{"raw_affiliation_string":"AlPlanta-Institute for Plant Research","institution_ids":[]},{"raw_affiliation_string":"Centre for Organismal Studies (COS) Heidelberg","institution_ids":["https://openalex.org/I223822909"]},{"raw_affiliation_string":"Heidelberg, Germany","institution_ids":[]},{"raw_affiliation_string":"Neustadt, Germany","institution_ids":[]},{"raw_affiliation_string":"RLP AgroScience GmbH","institution_ids":["https://openalex.org/I4210142180"]},{"raw_affiliation_string":"University of Heidelberg","institution_ids":["https://openalex.org/I223822909"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5066807390"],"corresponding_institution_ids":["https://openalex.org/I223822909","https://openalex.org/I4210142180"],"apc_list":null,"apc_paid":null,"fwci":1.4699,"has_fulltext":true,"cited_by_count":38,"citation_normalized_percentile":{"value":0.81128896,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"7","issue":"9","first_page":"1071","last_page":"1078"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.8999000191688538,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.8999000191688538,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11426","display_name":"Genetically Modified Organisms Research","score":0.020899999886751175,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10184","display_name":"Plant Molecular Biology Research","score":0.01769999973475933,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cg-methylation","display_name":"CG methylation","score":0.8619999885559082},{"id":"https://openalex.org/keywords/chg-methylation","display_name":"CHG methylation","score":0.9399999976158142},{"id":"https://openalex.org/keywords/chh-methylation","display_name":"CHH methylation","score":1.0},{"id":"https://openalex.org/keywords/rna-directed-dna-methylation","display_name":"RNA-directed DNA methylation","score":0.9649999737739563},{"id":"https://openalex.org/keywords/transgene-silencing","display_name":"transgene silencing","score":0.4580000042915344},{"id":"https://openalex.org/keywords/potato-spindle-tuber-viroid","display_name":"potato spindle tuber viroid","score":0.6050000190734863},{"id":"https://openalex.org/keywords/potato","display_name":"potato","score":0.5289999842643738},{"id":"https://openalex.org/keywords/transgenerational-epigenetic-inheritance","display_name":"transgenerational epigenetic inheritance","score":0.7149999737739563},{"id":"https://openalex.org/keywords/histone-h3-acetylation","display_name":"histone H3 acetylation","score":0.9279999732971191},{"id":"https://openalex.org/keywords/chromatin-modification","display_name":"chromatin modification","score":0.7739999890327454}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8845193386077881},{"id":"https://openalex.org/C33288867","wikidata":"https://www.wikidata.org/wiki/Q518328","display_name":"Methylation","level":3,"score":0.8217962980270386},{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.7227084040641785},{"id":"https://openalex.org/C102230213","wikidata":"https://www.wikidata.org/wiki/Q430117","display_name":"Transgene","level":3,"score":0.6912562251091003},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5612920522689819},{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.4976697266101837},{"id":"https://openalex.org/C101762097","wikidata":"https://www.wikidata.org/wiki/Q224093","display_name":"Promoter","level":4,"score":0.492603600025177},{"id":"https://openalex.org/C83640560","wikidata":"https://www.wikidata.org/wiki/Q180951","display_name":"Chromatin","level":3,"score":0.46304184198379517},{"id":"https://openalex.org/C163002167","wikidata":"https://www.wikidata.org/wiki/Q7277124","display_name":"RNA-Directed DNA Methylation","level":5,"score":0.4317302107810974},{"id":"https://openalex.org/C2776745794","wikidata":"https://www.wikidata.org/wiki/Q24777451","display_name":"Histone H3","level":4,"score":0.4289034605026245},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4282030463218689},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.11669453978538513}],"mesh":[{"descriptor_ui":"D000107","descriptor_name":"Acetylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003596","descriptor_name":"Cytosine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006657","descriptor_name":"Histones","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006657","descriptor_name":"Histones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008239","descriptor_name":"Lysine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010942","descriptor_name":"Plant Viruses","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014026","descriptor_name":"Nicotiana","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014772","descriptor_name":"Viroids","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016366","descriptor_name":"Open Reading Frames","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018899","descriptor_name":"CpG Islands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019076","descriptor_name":"Transgenes","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030821","descriptor_name":"Plants, Genetically Modified","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D030821","descriptor_name":"Plants, Genetically Modified","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D059372","descriptor_name":"Nucleotide Motifs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.4161/epi.21644","doi":"https://doi.org/10.4161/epi.21644","is_oa":true,"landing_page_url":"https://doi.org/10.4161/epi.21644","pdf_url":"https://www.tandfonline.com/doi/pdf/10.4161/epi.21644?needAccess=true&role=button","source":{"id":"https://openalex.org/S203437305","display_name":"Epigenetics","issn_l":"1559-2294","issn":["1559-2294","1559-2308"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315740","host_organization_name":"Landes Bioscience","host_organization_lineage":["https://openalex.org/P4310315740"],"host_organization_lineage_names":["Landes Bioscience"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epigenetics","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2747708","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3466191","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3466191","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3466191","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epigenetics","raw_type":"Text"},{"id":"pmid:22863736","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22863736","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epigenetics","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.4161/epi.21644","doi":"https://doi.org/10.4161/epi.21644","is_oa":true,"landing_page_url":"https://doi.org/10.4161/epi.21644","pdf_url":"https://www.tandfonline.com/doi/pdf/10.4161/epi.21644?needAccess=true&role=button","source":{"id":"https://openalex.org/S203437305","display_name":"Epigenetics","issn_l":"1559-2294","issn":["1559-2294","1559-2308"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315740","host_organization_name":"Landes Bioscience","host_organization_lineage":["https://openalex.org/P4310315740"],"host_organization_lineage_names":["Landes Bioscience"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epigenetics","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2017926012","display_name":null,"funder_award_id":"LSHG-CT-2006-037900","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G4076964855","display_name":null,"funder_award_id":"Wa1019/8-1","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2089294142.pdf","grobid_xml":"https://content.openalex.org/works/W2089294142.grobid-xml"},"referenced_works_count":55,"referenced_works":["https://openalex.org/W142357651","https://openalex.org/W1480969300","https://openalex.org/W1539789519","https://openalex.org/W1967655525","https://openalex.org/W1977171359","https://openalex.org/W1978716989","https://openalex.org/W1980436308","https://openalex.org/W1981669094","https://openalex.org/W1984251741","https://openalex.org/W1986247545","https://openalex.org/W1996877067","https://openalex.org/W2001224651","https://openalex.org/W2001476164","https://openalex.org/W2002804798","https://openalex.org/W2007250559","https://openalex.org/W2012865420","https://openalex.org/W2019853367","https://openalex.org/W2019896138","https://openalex.org/W2020236505","https://openalex.org/W2026177649","https://openalex.org/W2026343134","https://openalex.org/W2031556265","https://openalex.org/W2031828946","https://openalex.org/W2043284304","https://openalex.org/W2050183381","https://openalex.org/W2057162139","https://openalex.org/W2064745039","https://openalex.org/W2070062215","https://openalex.org/W2070792578","https://openalex.org/W2082694471","https://openalex.org/W2084225936","https://openalex.org/W2086153601","https://openalex.org/W2086698587","https://openalex.org/W2087874602","https://openalex.org/W2090829779","https://openalex.org/W2094861513","https://openalex.org/W2096526180","https://openalex.org/W2107632632","https://openalex.org/W2119923760","https://openalex.org/W2126606466","https://openalex.org/W2126729539","https://openalex.org/W2127243795","https://openalex.org/W2137483650","https://openalex.org/W2137794992","https://openalex.org/W2142338990","https://openalex.org/W2147620906","https://openalex.org/W2157978879","https://openalex.org/W2159159726","https://openalex.org/W2161044621","https://openalex.org/W2161631109","https://openalex.org/W2163121697","https://openalex.org/W2163414652","https://openalex.org/W2165834716","https://openalex.org/W2166083671","https://openalex.org/W2170294063"],"related_works":["https://openalex.org/W4321485137","https://openalex.org/W3109631008","https://openalex.org/W2070792578","https://openalex.org/W2767673985","https://openalex.org/W3118113464","https://openalex.org/W2758894366","https://openalex.org/W2566954290","https://openalex.org/W2966790616","https://openalex.org/W2795493428","https://openalex.org/W2018817711"],"abstract_inverted_index":{"In":[0,89],"plants,":[1,98],"RNA-directed":[2],"DNA":[3],"methylation":[4,18,38,57,103,110,125,153,174],"(RdDM)":[5],"can":[6,39,58,154],"target":[7],"both":[8],"transgene":[9,73,123],"promoters":[10,160],"and":[11,27,83,101],"coding":[12,55],"regions/gene":[13],"bodies.":[14],"RdDM":[15,33],"leads":[16],"to":[17,129],"of":[19,31,67,122,132,134,142,144,166,173,178],"cytosines":[20],"in":[21,45,95,159,163],"all":[22],"sequence":[23],"contexts:":[24],"CG,":[25,81],"CHG":[26,82,102],"CHH.":[28],"Upon":[29],"segregation":[30],"the":[32,46,65,120,149,164],"trigger,":[34],"at":[35,42,80,115],"least":[36,116],"CG":[37,109,152],"be":[40,59,155],"maintained":[41,113,156],"promoter":[43],"regions":[44],"progeny.":[47],"So":[48],"far,":[49],"it":[50],"is":[51],"not":[52,127,157],"clear":[53],"whether":[54],"region":[56],"also":[60,162],"maintained.":[61],"We":[62],"showed":[63],"that":[64,94,151,171],"body":[66,124,165],"Potato":[68],"spindle":[69],"tuber":[70],"viroid":[71],"(PSTVd)":[72],"constructs":[74],"became":[75],"densely":[76],"de":[77],"novo":[78],"methylated":[79],"CHH":[84,100],"sites":[85],"upon":[86],"PSTVd":[87],"infection.":[88],"this":[90],"study,":[91],"we":[92],"demonstrate":[93],"viroid-free":[96],"progeny":[97],"asymmetric":[99],"was":[104,111],"completely":[105],"lost.":[106],"However,":[107],"symmetric":[108],"stably":[112],"for":[114],"two":[117],"generations.":[118],"Importantly,":[119],"presence":[121],"did":[126],"lead":[128],"an":[130],"increase":[131],"dimethylation":[133],"histone":[135],"H3":[136],"lysine":[137],"9":[138],"or":[139],"a":[140],"decrease":[141],"acetylation":[143],"H3.":[145],"Our":[146],"data":[147],"supports":[148],"view":[150],"only":[158],"but":[161],"transgenes.":[167],"They":[168],"further":[169],"suggest":[170],"maintenance":[172],"may":[175],"occur":[176],"independently":[177],"tested":[179],"chromatin":[180],"modifications.":[181]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":8}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}