{"id":"https://openalex.org/W2089190844","doi":"https://doi.org/10.1002/hlca.200390137","title":"Helicity\u2010Encoded Molecular Strands: Efficient Access by the Hydrazone Route and Structural Features","display_name":"Helicity\u2010Encoded Molecular Strands: Efficient Access by the Hydrazone Route and Structural Features","publication_year":2003,"publication_date":"2003-05-01","ids":{"openalex":"https://openalex.org/W2089190844","doi":"https://doi.org/10.1002/hlca.200390137","mag":"2089190844"},"language":"en","primary_location":{"id":"doi:10.1002/hlca.200390137","doi":"https://doi.org/10.1002/hlca.200390137","is_oa":false,"landing_page_url":"https://doi.org/10.1002/hlca.200390137","pdf_url":null,"source":{"id":"https://openalex.org/S181847678","display_name":"Helvetica Chimica Acta","issn_l":"0018-019X","issn":["0018-019X","1522-2675"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Helvetica Chimica Acta","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061084560","display_name":"J.\u2010L. Schmitt","orcid":"https://orcid.org/0000-0001-8667-7941","observed_orcids":["https://orcid.org/0000-0001-8667-7941"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210095283","display_name":"Institut de Science et d'Ing\u00e9nierie Supramol\u00e9culaires","ror":"https://ror.org/00xts7d02","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4210095283","https://openalex.org/I4210128300","https://openalex.org/I68947357"]},{"id":"https://openalex.org/I4210134697","display_name":"\u00c9co-Anthropologie","ror":"https://ror.org/03x0yny97","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I204730241","https://openalex.org/I4210107625","https://openalex.org/I4210123595","https://openalex.org/I4210134697"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jean\u2010Louis Schmitt","raw_affiliation_strings":["ISIS-ULP-CNRS UMR 7006 8, alle\u0301e Gaspard Monge, BP 70028, F-67083 Strasbourg cedex (phone: 03 90 24 5145; fax 03 90 24 51 40","ISIS-ULP-CNRS UMR 7006 8, all\u00e9e Gaspard Monge, BP 70028, F-67083 Strasbourg cedex (phone: 03 90 24 5145","fax 03 90 24 51 40"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ISIS-ULP-CNRS UMR 7006 8, alle\u0301e Gaspard Monge, BP 70028, F-67083 Strasbourg cedex (phone: 03 90 24 5145; fax 03 90 24 51 40","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210095283","https://openalex.org/I4210134697"]},{"raw_affiliation_string":"ISIS-ULP-CNRS UMR 7006 8, all\u00e9e Gaspard Monge, BP 70028, F-67083 Strasbourg cedex (phone: 03 90 24 5145","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210095283","https://openalex.org/I4210134697"]},{"raw_affiliation_string":"fax 03 90 24 51 40","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043182649","display_name":"Adrian\u2010Mihail Stadler","orcid":"https://orcid.org/0000-0001-8150-6625","observed_orcids":["https://orcid.org/0000-0001-8150-6625"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210095283","display_name":"Institut de Science et d'Ing\u00e9nierie Supramol\u00e9culaires","ror":"https://ror.org/00xts7d02","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4210095283","https://openalex.org/I4210128300","https://openalex.org/I68947357"]},{"id":"https://openalex.org/I4210134697","display_name":"\u00c9co-Anthropologie","ror":"https://ror.org/03x0yny97","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I204730241","https://openalex.org/I4210107625","https://openalex.org/I4210123595","https://openalex.org/I4210134697"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Adrian\u2010Mihail Stadler","raw_affiliation_strings":["ISIS-ULP-CNRS UMR 7006 8, alle\u0301e Gaspard Monge, BP 70028, F-67083 Strasbourg cedex (phone: 03 90 24 5145; fax 03 90 24 51 40","ISIS-ULP-CNRS UMR 7006 8, all\u00e9e Gaspard Monge, BP 70028, F-67083 Strasbourg cedex (phone: 03 90 24 5145","fax 03 90 24 51 40"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ISIS-ULP-CNRS UMR 7006 8, alle\u0301e Gaspard Monge, BP 70028, F-67083 Strasbourg cedex (phone: 03 90 24 5145; fax 03 90 24 51 40","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210095283","https://openalex.org/I4210134697"]},{"raw_affiliation_string":"ISIS-ULP-CNRS UMR 7006 8, all\u00e9e Gaspard Monge, BP 70028, F-67083 Strasbourg cedex (phone: 03 90 24 5145","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210095283","https://openalex.org/I4210134697"]},{"raw_affiliation_string":"fax 03 90 24 51 40","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017154453","display_name":"Nathalie Kyritsakas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I68947357","display_name":"Universit\u00e9 de Strasbourg","ror":"https://ror.org/00pg6eq24","country_code":"FR","type":"education","lineage":["https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Nathalie Kyritsakas","raw_affiliation_strings":["Service Commun de Rayons X, Institut Le Bel, Universite\u0301 Louis Pasteur, 4, rue Blaise Pascal, F-67000 Strasbourg","Service Commun de Rayons X, Institut Le Bel, Universit\u00e9 Louis Pasteur, 4, rue Blaise Pascal, F-67000 Strasbourg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service Commun de Rayons X, Institut Le Bel, Universite\u0301 Louis Pasteur, 4, rue Blaise Pascal, F-67000 Strasbourg","institution_ids":["https://openalex.org/I68947357"]},{"raw_affiliation_string":"Service Commun de Rayons X, Institut Le Bel, Universit\u00e9 Louis Pasteur, 4, rue Blaise Pascal, F-67000 Strasbourg","institution_ids":["https://openalex.org/I68947357"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059296399","display_name":"Jean\u2010Mar\u00ede Lehn","orcid":"https://orcid.org/0000-0001-8981-4593","observed_orcids":["https://orcid.org/0000-0001-8981-4593"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210095283","display_name":"Institut de Science et d'Ing\u00e9nierie Supramol\u00e9culaires","ror":"https://ror.org/00xts7d02","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4210095283","https://openalex.org/I4210128300","https://openalex.org/I68947357"]},{"id":"https://openalex.org/I4210134697","display_name":"\u00c9co-Anthropologie","ror":"https://ror.org/03x0yny97","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I204730241","https://openalex.org/I4210107625","https://openalex.org/I4210123595","https://openalex.org/I4210134697"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Jean\u2010Marie Lehn","raw_affiliation_strings":["ISIS-ULP-CNRS UMR 7006 8, alle\u0301e Gaspard Monge, BP 70028, F-67083 Strasbourg cedex (phone: 03 90 24 5145; fax 03 90 24 51 40","ISIS-ULP-CNRS UMR 7006 8, all\u00e9e Gaspard Monge, BP 70028, F-67083 Strasbourg cedex (phone: 03 90 24 5145","fax 03 90 24 51 40"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ISIS-ULP-CNRS UMR 7006 8, alle\u0301e Gaspard Monge, BP 70028, F-67083 Strasbourg cedex (phone: 03 90 24 5145; fax 03 90 24 51 40","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210095283","https://openalex.org/I4210134697"]},{"raw_affiliation_string":"ISIS-ULP-CNRS UMR 7006 8, all\u00e9e Gaspard Monge, BP 70028, F-67083 Strasbourg cedex (phone: 03 90 24 5145","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210095283","https://openalex.org/I4210134697"]},{"raw_affiliation_string":"fax 03 90 24 51 40","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5059296399"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210095283","https://openalex.org/I4210134697"],"apc_list":{"value":4030,"currency":"USD","value_usd":4030},"apc_paid":null,"fwci":5.816,"has_fulltext":false,"cited_by_count":122,"citation_normalized_percentile":{"value":0.9726734,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"86","issue":"5","first_page":"1598","last_page":"1624"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10578","display_name":"Supramolecular Chemistry and Complexes","score":0.5659000277519226,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10578","display_name":"Supramolecular Chemistry and Complexes","score":0.5659000277519226,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.1941000074148178,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11298","display_name":"Synthesis and Properties of Aromatic Compounds","score":0.17180000245571136,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hydrazones","display_name":"hydrazones","score":0.8379999995231628},{"id":"https://openalex.org/keywords/pyridine","display_name":"pyridine","score":0.8059999942779541},{"id":"https://openalex.org/keywords/pyrimidines","display_name":"pyrimidines","score":0.9990000128746033},{"id":"https://openalex.org/keywords/molecular-folding","display_name":"molecular folding","score":0.44200000166893005},{"id":"https://openalex.org/keywords/crystal-structure","display_name":"crystal structure","score":0.4320000112056732},{"id":"https://openalex.org/keywords/nmr-spectroscopy","display_name":"NMR spectroscopy","score":0.6029999852180481},{"id":"https://openalex.org/keywords/helical-geometry","display_name":"helical geometry","score":0.5649999976158142}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.828069806098938},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.674095094203949},{"id":"https://openalex.org/C33347731","wikidata":"https://www.wikidata.org/wiki/Q285210","display_name":"Stacking","level":2,"score":0.6098516583442688},{"id":"https://openalex.org/C2780349576","wikidata":"https://www.wikidata.org/wiki/Q416007","display_name":"Hydrazone","level":2,"score":0.5861194133758545},{"id":"https://openalex.org/C2775859700","wikidata":"https://www.wikidata.org/wiki/Q568855","display_name":"Helicity","level":2,"score":0.5281141996383667},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.5229367017745972},{"id":"https://openalex.org/C2779485729","wikidata":"https://www.wikidata.org/wiki/Q210385","display_name":"Pyridine","level":2,"score":0.45078176259994507},{"id":"https://openalex.org/C2776545253","wikidata":"https://www.wikidata.org/wiki/Q5464292","display_name":"Folding (DSP implementation)","level":2,"score":0.4451867938041687},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.07648366689682007},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C109214941","wikidata":"https://www.wikidata.org/wiki/Q18334","display_name":"Particle physics","level":1,"score":0.0},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/hlca.200390137","doi":"https://doi.org/10.1002/hlca.200390137","is_oa":false,"landing_page_url":"https://doi.org/10.1002/hlca.200390137","pdf_url":null,"source":{"id":"https://openalex.org/S181847678","display_name":"Helvetica Chimica Acta","issn_l":"0018-019X","issn":["0018-019X","1522-2675"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Helvetica Chimica Acta","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W1484701672","https://openalex.org/W1648880131","https://openalex.org/W1974029107","https://openalex.org/W1976038941","https://openalex.org/W1981521415","https://openalex.org/W1982544255","https://openalex.org/W1987523172","https://openalex.org/W1989241604","https://openalex.org/W1993043024","https://openalex.org/W1993515963","https://openalex.org/W1995993833","https://openalex.org/W1996915558","https://openalex.org/W2000244482","https://openalex.org/W2007502678","https://openalex.org/W2035826781","https://openalex.org/W2042584758","https://openalex.org/W2043295113","https://openalex.org/W2048568564","https://openalex.org/W2049950564","https://openalex.org/W2051468556","https://openalex.org/W2052405490","https://openalex.org/W2055369556","https://openalex.org/W2056928922","https://openalex.org/W2064572741","https://openalex.org/W2079503050","https://openalex.org/W2080936474","https://openalex.org/W2083468080","https://openalex.org/W2096649736","https://openalex.org/W2105941779","https://openalex.org/W2109466768","https://openalex.org/W2119364052","https://openalex.org/W2120399594","https://openalex.org/W2165378894","https://openalex.org/W2171109575","https://openalex.org/W2953209004","https://openalex.org/W4242959619"],"related_works":["https://openalex.org/W2080936474","https://openalex.org/W2082233082","https://openalex.org/W2109466768","https://openalex.org/W1976038941","https://openalex.org/W1838110516","https://openalex.org/W4213366739","https://openalex.org/W2069212852","https://openalex.org/W8184392","https://openalex.org/W1987523172","https://openalex.org/W2618409715"],"abstract_inverted_index":{"Abstract":[0],"Control":[1],"over":[2],"the":[3,15,47,59,130,136,146,165,182],"folding":[4],"of":[5,14,22,28,55,61,66,78,85,93,96,135,139,164,176],"molecular":[6],"strands":[7,74,95],"may":[8],"be":[9],"achieved":[10],"by":[11,83,125,133],"appropriate":[12],"choice":[13],"constituting":[16],"subunits,":[17],"in":[18,123,129],"particular":[19],"for":[20,174],"chains":[21],"specific":[23],"heterocycles":[24],"such":[25,94,141],"as":[26,168,170],"sequences":[27,84],"directly":[29],"connected":[30],"pyridine":[31],"(py)":[32],"and":[33,63,81,88,128,156,162],"pyrimidine":[34],"(pym)":[35],"rings,":[36],"which":[37],"are":[38],"known":[39],"to":[40,73,100,152],"fold":[41,114],"into":[42,116],"extended":[43],"helical":[44,117,148],"structures.":[45],"Since":[46],"hydrazone":[48],"(hyz)":[49],"group":[50],"represents":[51],"an":[52],"isomorphic":[53],"analogue":[54],"a":[56,69,185],"py":[57,79],"site,":[58],"condensation":[60],"hydrazine":[62],"carboxaldehyde":[64],"derivatives":[65],"pym":[67,89],"offers":[68],"very":[70],"efficient":[71],"approach":[72,167],"incorporating":[75],"hyz":[76,87,102],"instead":[77],"units":[80],"constituted":[82],"alternating":[86],"groups.":[90],"A":[91],"series":[92],"different":[97],"lengths,":[98],"up":[99,151],"ten":[101],"units,":[103],"i.e.,":[104],"1\u20137,":[105],"were":[106],"synthesized.":[107],"Their":[108],"spectral":[109],"properties":[110],"indicate":[111],"that":[112],"they":[113],"indeed":[115],"shapes.":[118],"Extensive":[119],"characterization":[120],"was":[121],"performed":[122],"solution":[124],"1HNMR":[126],"spectroscopy":[127],"solid":[131],"state":[132],"determination":[134],"crystal":[137],"structures":[138],"eight":[140],"strands.":[142],"They":[143],"all":[144],"display":[145],"expected":[147],"geometry":[149],"with":[150],"3":[153],"1/3":[154],"turns":[155],"direct":[157],"stacking":[158],"contacts.":[159],"The":[160],"efficiency":[161],"flexibility":[163],"synthetic":[166],"well":[169],"its":[171],"wide":[172],"potential":[173],"generation":[175],"diversity":[177],"through":[178],"lateral":[179],"decoration":[180],"make":[181],"(hyz\uf8ffpym)":[183],"subunit":[184],"particularly":[186],"attractive":[187],"helicity":[188],"codon.":[189]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":11},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":11},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}