{"id":"https://openalex.org/W2089090135","doi":"https://doi.org/10.1111/j.1432-1033.1983.tb07346.x","title":"Membrane Topology of ATP Synthase from Bovine Heart Mitochondira and Escherichia coli","display_name":"Membrane Topology of ATP Synthase from Bovine Heart Mitochondira and Escherichia coli","publication_year":1983,"publication_date":"1983-04-01","ids":{"openalex":"https://openalex.org/W2089090135","doi":"https://doi.org/10.1111/j.1432-1033.1983.tb07346.x","mag":"2089090135","pmid":"https://pubmed.ncbi.nlm.nih.gov/6301821"},"language":"en","primary_location":{"id":"doi:10.1111/j.1432-1033.1983.tb07346.x","doi":"https://doi.org/10.1111/j.1432-1033.1983.tb07346.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1432-1033.1983.tb07346.x","pdf_url":null,"source":{"id":"https://openalex.org/S4210214924","display_name":"European Journal of Biochemistry","issn_l":"0014-2956","issn":["0014-2956","0945-5795","1432-1033"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-100"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Biochemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091033956","display_name":"Cesare Montecucco","orcid":"https://orcid.org/0000-0001-7361-5688","observed_orcids":["https://orcid.org/0000-0001-7361-5688"]},"institutions":[{"id":"https://openalex.org/I138689650","display_name":"University of Padua","ror":"https://ror.org/00240q980","country_code":"IT","type":"education","lineage":["https://openalex.org/I138689650"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Cesare MONTECUCCO","raw_affiliation_strings":["Instituto di Patologia Generale, Universiti degli Studi di Padova, Via Loredan 16, I-35100 Padova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto di Patologia Generale, Universiti degli Studi di Padova, Via Loredan 16, I-35100 Padova, Italy","institution_ids":["https://openalex.org/I138689650"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009045576","display_name":"Federica Dabbeni\u2010Sala","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I138689650","display_name":"University of Padua","ror":"https://ror.org/00240q980","country_code":"IT","type":"education","lineage":["https://openalex.org/I138689650"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Federica DABBENI\u2010SALA","raw_affiliation_strings":["Instituto di Farmacologia, Largo Mencghetti, 2, 1-35100 Padova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto di Farmacologia, Largo Mencghetti, 2, 1-35100 Padova, Italy","institution_ids":["https://openalex.org/I138689650"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026527299","display_name":"Peter Friedl","orcid":"https://orcid.org/0000-0002-0119-4041","observed_orcids":["https://orcid.org/0000-0002-0119-4041"]},"institutions":[{"id":"https://openalex.org/I4210124929","display_name":"Helmholtz Centre for Infection Research","ror":"https://ror.org/03d0p2685","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I4210124929"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Peter FRIEDL","raw_affiliation_strings":["Gesellschaft fu\u0308r Biotechnologische Forschung mbH, Mascheroder Weg 1, D-3300 Braunschweig-Sto\u0308ckheim, Federal Republic of Germany","Gesellschaft f\u00fcr Biotechnologische Forschung mbH, Mascheroder Weg 1, D\u20103300 Braunschweig\u2010St\u00f6ckheim, Federal Republic of Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gesellschaft fu\u0308r Biotechnologische Forschung mbH, Mascheroder Weg 1, D-3300 Braunschweig-Sto\u0308ckheim, Federal Republic of Germany","institution_ids":["https://openalex.org/I4210124929"]},{"raw_affiliation_string":"Gesellschaft f\u00fcr Biotechnologische Forschung mbH, Mascheroder Weg 1, D\u20103300 Braunschweig\u2010St\u00f6ckheim, Federal Republic of Germany","institution_ids":["https://openalex.org/I4210124929"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5056111497","display_name":"Yves M. Galante","orcid":"https://orcid.org/0000-0002-6700-5514","observed_orcids":["https://orcid.org/0000-0002-6700-5514"]},"institutions":[{"id":"https://openalex.org/I4210094275","display_name":"MSD (France)","ror":"https://ror.org/00kt5kp12","country_code":"FR","type":"company","lineage":["https://openalex.org/I1285764155","https://openalex.org/I4210094275"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Yves M. GALANTE","raw_affiliation_strings":["Laboratories Merck-Sharp & Dohme-Chibret, Centre de Recherche Boi\u0302te Postale 127, Route de Marsat, Riom, France","Laboratories Merck\u2010Sharp & Dohme\u2010Chibret, Centre de Recherche Bo\u00eete Postale 127, Route de Marsat, Riom, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratories Merck-Sharp & Dohme-Chibret, Centre de Recherche Boi\u0302te Postale 127, Route de Marsat, Riom, France","institution_ids":["https://openalex.org/I4210094275"]},{"raw_affiliation_string":"Laboratories Merck\u2010Sharp & Dohme\u2010Chibret, Centre de Recherche Bo\u00eete Postale 127, Route de Marsat, Riom, France","institution_ids":["https://openalex.org/I4210094275"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.0032,"has_fulltext":false,"cited_by_count":51,"citation_normalized_percentile":{"value":0.87163709,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"132","issue":"1","first_page":"189","last_page":"194"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12763","display_name":"ATP Synthase and ATPases Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12763","display_name":"ATP Synthase and ATPases Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/atp-synthase","display_name":"ATP synthase","score":0.9900000095367432},{"id":"https://openalex.org/keywords/membrane-protein-topology","display_name":"membrane topology","score":0.9049999713897705},{"id":"https://openalex.org/keywords/bovine-heart-mitochondria","display_name":"bovine heart mitochondria","score":0.828000009059906},{"id":"https://openalex.org/keywords/escherichia-coli","display_name":"Escherichia coli","score":0.8820000290870667},{"id":"https://openalex.org/keywords/b-subunit","display_name":"B subunit","score":0.6539999842643738},{"id":"https://openalex.org/keywords/subunit-c","display_name":"subunit c","score":0.9700000286102295},{"id":"https://openalex.org/keywords/adenine-nucleotide-carrier","display_name":"adenine nucleotide carrier","score":0.9399999976158142},{"id":"https://openalex.org/keywords/subunit-molecular-weight","display_name":"subunit molecular weight","score":0.3700000047683716},{"id":"https://openalex.org/keywords/mitochondrial-atp-synthase","display_name":"mitochondrial ATP synthase","score":0.4779999852180481}],"concepts":[{"id":"https://openalex.org/C112243037","wikidata":"https://www.wikidata.org/wiki/Q22327117","display_name":"ATP synthase","level":3,"score":0.8136467933654785},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.708980917930603},{"id":"https://openalex.org/C23265538","wikidata":"https://www.wikidata.org/wiki/Q300033","display_name":"ATPase","level":3,"score":0.685284435749054},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.625880777835846},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.615181565284729},{"id":"https://openalex.org/C28859421","wikidata":"https://www.wikidata.org/wiki/Q39572","display_name":"Mitochondrion","level":2,"score":0.6027095913887024},{"id":"https://openalex.org/C104292427","wikidata":"https://www.wikidata.org/wiki/Q899781","display_name":"Protein subunit","level":3,"score":0.5763570666313171},{"id":"https://openalex.org/C512185932","wikidata":"https://www.wikidata.org/wiki/Q28745","display_name":"Nucleotide","level":3,"score":0.4879100024700165},{"id":"https://openalex.org/C2779564974","wikidata":"https://www.wikidata.org/wiki/Q80863","display_name":"Adenosine triphosphate","level":2,"score":0.4754626154899597},{"id":"https://openalex.org/C75385678","wikidata":"https://www.wikidata.org/wiki/Q4896390","display_name":"Inner mitochondrial membrane","level":3,"score":0.44698572158813477},{"id":"https://openalex.org/C553450214","wikidata":"https://www.wikidata.org/wiki/Q851162","display_name":"Biosynthesis","level":3,"score":0.4409335255622864},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4197067320346832},{"id":"https://openalex.org/C2780523633","wikidata":"https://www.wikidata.org/wiki/Q380709","display_name":"Labelling","level":2,"score":0.415242463350296},{"id":"https://openalex.org/C119120687","wikidata":"https://www.wikidata.org/wiki/Q4654890","display_name":"ATP synthase gamma subunit","level":5,"score":0.41201114654541016},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.40963056683540344},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3918583393096924},{"id":"https://openalex.org/C141315368","wikidata":"https://www.wikidata.org/wiki/Q4654881","display_name":"ATP hydrolysis","level":4,"score":0.12717875838279724},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.10291352868080139}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002621","descriptor_name":"Chemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004591","descriptor_name":"Electrophoresis, Polyacrylamide Gel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D007553","descriptor_name":"Isotope Labeling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008563","descriptor_name":"Membrane Lipids","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008929","descriptor_name":"Mitochondria, Heart","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D009097","descriptor_name":"Multienzyme Complexes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010446","descriptor_name":"Peptide Fragments","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010770","descriptor_name":"Phosphotransferases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010777","descriptor_name":"Photochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D025181","descriptor_name":"ATP Synthetase Complexes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055598","descriptor_name":"Chemical Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1111/j.1432-1033.1983.tb07346.x","doi":"https://doi.org/10.1111/j.1432-1033.1983.tb07346.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1432-1033.1983.tb07346.x","pdf_url":null,"source":{"id":"https://openalex.org/S4210214924","display_name":"European Journal of Biochemistry","issn_l":"0014-2956","issn":["0014-2956","0945-5795","1432-1033"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-100"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Biochemistry","raw_type":"journal-article"},{"id":"pmid:6301821","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6301821","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of biochemistry","raw_type":"Comparative Study"},{"id":"pmh:oai:www.research.unipd.it:11577/2509124","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11577/2509124","pdf_url":null,"source":{"id":"https://openalex.org/S4306402547","display_name":"Padua Research Archive (University of Padova)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I138689650","host_organization_name":"University of Padua","host_organization_lineage":["https://openalex.org/I138689650"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W59350189","https://openalex.org/W145552401","https://openalex.org/W853523725","https://openalex.org/W1483271114","https://openalex.org/W1498229119","https://openalex.org/W1498753987","https://openalex.org/W1546756166","https://openalex.org/W1560761357","https://openalex.org/W1560936920","https://openalex.org/W1594919188","https://openalex.org/W1596073986","https://openalex.org/W1597027477","https://openalex.org/W1606616864","https://openalex.org/W1608912346","https://openalex.org/W1965010526","https://openalex.org/W1976645065","https://openalex.org/W1981493413","https://openalex.org/W1981585875","https://openalex.org/W1982835219","https://openalex.org/W1992076592","https://openalex.org/W1996332655","https://openalex.org/W2000915471","https://openalex.org/W2007575173","https://openalex.org/W2025759141","https://openalex.org/W2033328871","https://openalex.org/W2034277598","https://openalex.org/W2042954596","https://openalex.org/W2043916998","https://openalex.org/W2045667596","https://openalex.org/W2048249160","https://openalex.org/W2048300428","https://openalex.org/W2048805937","https://openalex.org/W2053358938","https://openalex.org/W2072779835","https://openalex.org/W2094265567","https://openalex.org/W2098310715","https://openalex.org/W2100837269","https://openalex.org/W2150227713","https://openalex.org/W2230409106","https://openalex.org/W2290627139","https://openalex.org/W2326442082","https://openalex.org/W4229648379"],"related_works":["https://openalex.org/W6992699982","https://openalex.org/W2000285789","https://openalex.org/W1522243590","https://openalex.org/W1593528019","https://openalex.org/W2071071439","https://openalex.org/W2080274969","https://openalex.org/W1519883796","https://openalex.org/W7097987152","https://openalex.org/W2271129044","https://openalex.org/W2072615411"],"abstract_inverted_index":{"The":[0,45,87],"polypeptides":[1,74,127],"exposed":[2],"to":[3,33,63,101],"lipids":[4],"in":[5,31],"the":[6,11,36,40,58,95,103,108,143,149],"membranous":[7],"F0":[8],"sector":[9],"of":[10,75,90,110,128,152],"mitochondrial":[12,43,59],"and":[13,53,83,138,159],"Escherichia":[14],"coli":[15,148],"ATP":[16,55],"synthases":[17],"were":[18,29,85,140],"labelled":[19],"with":[20,94,156,164],"radioactive":[21],"photoreactive":[22],"lipids.":[23],"Highly":[24],"resolving":[25],"gel":[26],"electrophoretic":[27],"conditions":[28],"used":[30],"order":[32],"separate":[34],"all":[35],"eighteen":[37],"components":[38],"forming":[39],"bovine":[41],"heart":[42],"enzyme.":[44],"hydrophobic":[46],"labelling":[47,153],"was":[48,92,154],"performed":[49],"on":[50],"fully":[51],"active":[52],"inhibitor-sensitive":[54],"synthases.":[56],"In":[57,107,142],"enzyme":[60],"prepared":[61],"according":[62],"Serrano":[64],"et":[65,112],"al.":[66],"(1976)":[67],"[J.":[68,121],"Biol.":[69,122],"Chem.":[70,123],"251,":[71],"2453-2461]":[72],"seven":[73],"Mr":[76,129],"30500;":[77],"11500;":[78,132],"10500;":[79,133],"10000;":[80,134],"9500;":[81,135],"8500":[82,137],"4500":[84,139],"labelled.":[86,141],"major":[88,150],"amount":[89,151],"radioactivity":[91],"associated":[93,155],"30500-Mr":[96],"component,":[97],"which":[98,115],"is":[99],"thought":[100],"be":[102],"adenine":[104],"nucleotide":[105],"carrier.":[106],"preparation":[109],"Galante":[111],"al.,":[113],"(1979)":[114],"almost":[116],"completely":[117],"lacks":[118],"this":[119],"component":[120],"254,":[124],"12372-12378]":[125],"nine":[126],"25000;":[130],"21000;":[131],"9200;":[136],"ATPase":[144],"synthase":[145],"from":[146],"E.":[147],"subunit":[157,165],"b":[158],"only":[160],"a":[161],"minor":[162],"portion":[163],"c.":[166]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}