{"id":"https://openalex.org/W2088344922","doi":"https://doi.org/10.1016/j.gene.2006.08.004","title":"cDNA cloning, gene organization and variant specific expression of HIF-1\u03b1 in high altitude yak (Bos grunniens)","display_name":"cDNA cloning, gene organization and variant specific expression of HIF-1\u03b1 in high altitude yak (Bos grunniens)","publication_year":2006,"publication_date":"2006-08-25","ids":{"openalex":"https://openalex.org/W2088344922","doi":"https://doi.org/10.1016/j.gene.2006.08.004","mag":"2088344922","pmid":"https://pubmed.ncbi.nlm.nih.gov/17045424"},"language":"en","primary_location":{"id":"doi:10.1016/j.gene.2006.08.004","doi":"https://doi.org/10.1016/j.gene.2006.08.004","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.gene.2006.08.004","pdf_url":null,"source":{"id":"https://openalex.org/S75702506","display_name":"Gene","issn_l":"0378-1119","issn":["0378-1119","1879-0038"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gene","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058019569","display_name":"Karamjit Singh Dolt","orcid":"https://orcid.org/0000-0002-0584-7505","observed_orcids":["https://orcid.org/0000-0002-0584-7505"]},"institutions":[{"id":"https://openalex.org/I177828482","display_name":"Institute of Genomics and Integrative Biology","ror":"https://ror.org/05ef28661","country_code":"IN","type":"facility","lineage":["https://openalex.org/I177828482","https://openalex.org/I2799351866","https://openalex.org/I4210134808","https://openalex.org/I66760702"]},{"id":"https://openalex.org/I19716509","display_name":"Jamia Hamdard","ror":"https://ror.org/03dwxvb85","country_code":"IN","type":"education","lineage":["https://openalex.org/I19716509"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Karamjit S. Dolt","raw_affiliation_strings":["Institute of Genomics and Integrative Biology, Mall Road, Delhi-110 007, India","Department of Biochemistry, Jamia Hamdard, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Genomics and Integrative Biology, Mall Road, Delhi-110 007, India","institution_ids":["https://openalex.org/I177828482"]},{"raw_affiliation_string":"Department of Biochemistry, Jamia Hamdard, New Delhi, India","institution_ids":["https://openalex.org/I19716509"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089428101","display_name":"Manoj K. Mishra","orcid":"https://orcid.org/0000-0002-3402-388X","observed_orcids":["https://orcid.org/0000-0002-3402-388X"]},"institutions":[{"id":"https://openalex.org/I177828482","display_name":"Institute of Genomics and Integrative Biology","ror":"https://ror.org/05ef28661","country_code":"IN","type":"facility","lineage":["https://openalex.org/I177828482","https://openalex.org/I2799351866","https://openalex.org/I4210134808","https://openalex.org/I66760702"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Manoj K. Mishra","raw_affiliation_strings":["Institute of Genomics and Integrative Biology, Mall Road, Delhi-110 007, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Genomics and Integrative Biology, Mall Road, Delhi-110 007, India","institution_ids":["https://openalex.org/I177828482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002264414","display_name":"Jayashree Karar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177828482","display_name":"Institute of Genomics and Integrative Biology","ror":"https://ror.org/05ef28661","country_code":"IN","type":"facility","lineage":["https://openalex.org/I177828482","https://openalex.org/I2799351866","https://openalex.org/I4210134808","https://openalex.org/I66760702"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Jayashree Karar","raw_affiliation_strings":["Institute of Genomics and Integrative Biology, Mall Road, Delhi-110 007, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Genomics and Integrative Biology, Mall Road, Delhi-110 007, India","institution_ids":["https://openalex.org/I177828482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109099203","display_name":"Masroor A. Baig","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19716509","display_name":"Jamia Hamdard","ror":"https://ror.org/03dwxvb85","country_code":"IN","type":"education","lineage":["https://openalex.org/I19716509"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Masroor A. Baig","raw_affiliation_strings":["Department of Biochemistry, Jamia Hamdard, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Jamia Hamdard, New Delhi, India","institution_ids":["https://openalex.org/I19716509"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113626279","display_name":"Zakwan Ahmed","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1340206300","display_name":"Defence Research and Development Organisation","ror":"https://ror.org/05k37v296","country_code":"IN","type":"government","lineage":["https://openalex.org/I1340206300","https://openalex.org/I2799351866","https://openalex.org/I4210150591"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Zakwan Ahmed","raw_affiliation_strings":["Field Research Laboratory, DRDO, Leh, Ladakh, J and K, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Field Research Laboratory, DRDO, Leh, Ladakh, J and K, India","institution_ids":["https://openalex.org/I1340206300"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020959869","display_name":"M. A. Qadar Pasha","orcid":"https://orcid.org/0000-0003-4126-6860","observed_orcids":["https://orcid.org/0000-0003-4126-6860"]},"institutions":[{"id":"https://openalex.org/I177828482","display_name":"Institute of Genomics and Integrative Biology","ror":"https://ror.org/05ef28661","country_code":"IN","type":"facility","lineage":["https://openalex.org/I177828482","https://openalex.org/I2799351866","https://openalex.org/I4210134808","https://openalex.org/I66760702"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"M.A. Qadar Pasha","raw_affiliation_strings":["Institute of Genomics and Integrative Biology, Mall Road, Delhi-110 007, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Genomics and Integrative Biology, Mall Road, Delhi-110 007, India","institution_ids":["https://openalex.org/I177828482"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5020959869"],"corresponding_institution_ids":["https://openalex.org/I177828482"],"apc_list":{"value":3300,"currency":"USD","value_usd":3300},"apc_paid":null,"fwci":2.0491,"has_fulltext":false,"cited_by_count":67,"citation_normalized_percentile":{"value":0.84550861,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"386","issue":"1-2","first_page":"73","last_page":"80"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11968","display_name":"High Altitude and Hypoxia","score":0.9761000275611877,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11968","display_name":"High Altitude and Hypoxia","score":0.9761000275611877,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10631","display_name":"Cancer, Hypoxia, and Metabolism","score":0.009200000204145908,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11056","display_name":"Physiological and biochemical adaptations","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hif-1alpha","display_name":"HIF-1\u03b1","score":0.902999997138977},{"id":"https://openalex.org/keywords/yak","display_name":"yak","score":0.9940000176429749},{"id":"https://openalex.org/keywords/high-altitude-adaptation","display_name":"high-altitude adaptation","score":0.9449999928474426},{"id":"https://openalex.org/keywords/hypoxia","display_name":"hypoxia","score":0.8939999938011169},{"id":"https://openalex.org/keywords/cdna-cloning","display_name":"cDNA cloning","score":0.8690000176429749},{"id":"https://openalex.org/keywords/gene-structure","display_name":"gene structure","score":0.8029999732971191},{"id":"https://openalex.org/keywords/mirna-target-prediction","display_name":"miRNA target prediction","score":0.7160000205039978},{"id":"https://openalex.org/keywords/mir-107","display_name":"miR-107","score":0.9909999966621399},{"id":"https://openalex.org/keywords/mir-18b","display_name":"miR-18b","score":0.9639999866485596},{"id":"https://openalex.org/keywords/mir-135a","display_name":"miR-135a","score":0.9990000128746033},{"id":"https://openalex.org/keywords/tissue-specific-expression","display_name":"tissue-specific gene expression","score":0.8339999914169312},{"id":"https://openalex.org/keywords/mrna-stability","display_name":"mRNA stability","score":0.7379999756813049},{"id":"https://openalex.org/keywords/oxygen-homeostasis","display_name":"oxygen homeostasis","score":0.6819999814033508},{"id":"https://openalex.org/keywords/evolutionary-conservation","display_name":"evolutionary conservation","score":0.5199999809265137}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9023571014404297},{"id":"https://openalex.org/C187882448","wikidata":"https://www.wikidata.org/wiki/Q283478","display_name":"Complementary DNA","level":3,"score":0.7387325763702393},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.6090617179870605},{"id":"https://openalex.org/C89604277","wikidata":"https://www.wikidata.org/wiki/Q424345","display_name":"Untranslated region","level":4,"score":0.5888904929161072},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.566206157207489},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.5237769484519958},{"id":"https://openalex.org/C160450060","wikidata":"https://www.wikidata.org/wiki/Q104598479","display_name":"Hypoxia-inducible factors","level":3,"score":0.4716096520423889},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.47112059593200684},{"id":"https://openalex.org/C121050878","wikidata":"https://www.wikidata.org/wiki/Q5135020","display_name":"Cloning (programming)","level":2,"score":0.4433457553386688},{"id":"https://openalex.org/C50724178","wikidata":"https://www.wikidata.org/wiki/Q381434","display_name":"Rapid amplification of cDNA ends","level":5,"score":0.44203850626945496},{"id":"https://openalex.org/C19924922","wikidata":"https://www.wikidata.org/wiki/Q408351","display_name":"Molecular cloning","level":4,"score":0.3520694971084595},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2785987854003906},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000531","descriptor_name":"Altitude","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051795","descriptor_name":"Hypoxia-Inducible Factor 1, alpha Subunit","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D051795","descriptor_name":"Hypoxia-Inducible Factor 1, alpha Subunit","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D051795","descriptor_name":"Hypoxia-Inducible Factor 1, alpha Subunit","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.gene.2006.08.004","doi":"https://doi.org/10.1016/j.gene.2006.08.004","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.gene.2006.08.004","pdf_url":null,"source":{"id":"https://openalex.org/S75702506","display_name":"Gene","issn_l":"0378-1119","issn":["0378-1119","1879-0038"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gene","raw_type":"journal-article"},{"id":"pmid:17045424","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17045424","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gene","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320721","display_name":"Council of Scientific and Industrial Research, India","ror":"https://ror.org/021wm7p51"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W144423133","https://openalex.org/W197290738","https://openalex.org/W1499828034","https://openalex.org/W1520440700","https://openalex.org/W1530921593","https://openalex.org/W1578283200","https://openalex.org/W1758605856","https://openalex.org/W1965306643","https://openalex.org/W1972032694","https://openalex.org/W1972538857","https://openalex.org/W1979950686","https://openalex.org/W1997588603","https://openalex.org/W2013818100","https://openalex.org/W2013994555","https://openalex.org/W2029706883","https://openalex.org/W2034767282","https://openalex.org/W2038518120","https://openalex.org/W2051700732","https://openalex.org/W2073406288","https://openalex.org/W2075054245","https://openalex.org/W2077928306","https://openalex.org/W2080532845","https://openalex.org/W2084792844","https://openalex.org/W2085609942","https://openalex.org/W2086447178","https://openalex.org/W2098972920","https://openalex.org/W2102526923","https://openalex.org/W2109492293","https://openalex.org/W2116667553","https://openalex.org/W2117692193","https://openalex.org/W2132968779","https://openalex.org/W2140753483","https://openalex.org/W2141392598","https://openalex.org/W2143613797","https://openalex.org/W2164170287","https://openalex.org/W2169600668","https://openalex.org/W2171289778","https://openalex.org/W2444223143","https://openalex.org/W2462650924","https://openalex.org/W6630978385","https://openalex.org/W6681115383"],"related_works":["https://openalex.org/W2077063815","https://openalex.org/W2032218821","https://openalex.org/W2472984890","https://openalex.org/W1987371643","https://openalex.org/W2051700732","https://openalex.org/W2382050942","https://openalex.org/W3044942699","https://openalex.org/W1520440700","https://openalex.org/W2931281847","https://openalex.org/W2348614781"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":15},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}