{"id":"https://openalex.org/W2088055680","doi":"https://doi.org/10.1016/j.apsb.2013.08.003","title":"Simultaneous determination of eight bioactive bakkenolides of Petasites tatewakianus Kitam by HPLC\u2013UV","display_name":"Simultaneous determination of eight bioactive bakkenolides of Petasites tatewakianus Kitam by HPLC\u2013UV","publication_year":2013,"publication_date":"2013-09-01","ids":{"openalex":"https://openalex.org/W2088055680","doi":"https://doi.org/10.1016/j.apsb.2013.08.003","mag":"2088055680"},"language":"en","primary_location":{"id":"doi:10.1016/j.apsb.2013.08.003","doi":"https://doi.org/10.1016/j.apsb.2013.08.003","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.apsb.2013.08.003","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2211383513000798/pdf","source":{"id":"https://openalex.org/S2736993989","display_name":"Acta Pharmaceutica Sinica B","issn_l":"2211-3835","issn":["2211-3835","2211-3843"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-140"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Pharmaceutica Sinica B","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.sciencedirect.com/science/article/pii/S2211383513000798/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100516834","display_name":"Jian-ming He","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianming He","raw_affiliation_strings":["Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, Shanghai 200433, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, Shanghai 200433, China","institution_ids":["https://openalex.org/I177933477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079396359","display_name":"Qin Wang","orcid":"https://orcid.org/0000-0002-1079-5914","observed_orcids":["https://orcid.org/0000-0002-1079-5914"]},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qin Wang","raw_affiliation_strings":["Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, Shanghai 200433, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, Shanghai 200433, China","institution_ids":["https://openalex.org/I177933477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100322872","display_name":"Yan Wang","orcid":"https://orcid.org/0000-0003-0671-7312","observed_orcids":["https://orcid.org/0000-0003-0671-7312","https://orcid.org/0000-0003-3934-9835","https://orcid.org/0009-0002-2442-7992","https://orcid.org/0000-0002-0379-9386"]},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yan Wang","raw_affiliation_strings":["Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, Shanghai 200433, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, Shanghai 200433, China","institution_ids":["https://openalex.org/I177933477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051571241","display_name":"Ruibing Chen","orcid":"https://orcid.org/0000-0002-1149-8049","observed_orcids":["https://orcid.org/0000-0002-1149-8049"]},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ruibing Chen","raw_affiliation_strings":["Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, Shanghai 200433, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, Shanghai 200433, China","institution_ids":["https://openalex.org/I177933477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100409571","display_name":"Yuyang Zhang","orcid":"https://orcid.org/0000-0002-5341-0682","observed_orcids":["https://orcid.org/0000-0002-5341-0682"]},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuyang Zhang","raw_affiliation_strings":["Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, Shanghai 200433, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, Shanghai 200433, China","institution_ids":["https://openalex.org/I177933477"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102937612","display_name":"Meili Guo","orcid":"https://orcid.org/0000-0003-4858-1396","observed_orcids":["https://orcid.org/0000-0003-4858-1396"]},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Meili Guo","raw_affiliation_strings":["Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, Shanghai 200433, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, Shanghai 200433, China","institution_ids":["https://openalex.org/I177933477"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5102937612"],"corresponding_institution_ids":["https://openalex.org/I177933477"],"apc_list":{"value":2600,"currency":"USD","value_usd":2600},"apc_paid":{"value":2600,"currency":"USD","value_usd":2600},"fwci":0.0,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.20129179,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"3","issue":"5","first_page":"354","last_page":"360"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11709","display_name":"Traditional Chinese Medicine Analysis","score":0.9711999893188477,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11709","display_name":"Traditional Chinese Medicine Analysis","score":0.9711999893188477,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11460","display_name":"Analytical Methods in Pharmaceuticals","score":0.009600000455975533,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13128","display_name":"Chromatography in Natural Products","score":0.006200000178068876,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/simultaneous-determination","display_name":"simultaneous determination","score":0.5899999737739563},{"id":"https://openalex.org/keywords/quality-assessment","display_name":"quality assessment","score":0.5649999976158142},{"id":"https://openalex.org/keywords/rhizome","display_name":"rhizome","score":0.9309999942779541},{"id":"https://openalex.org/keywords/geographical-origin","display_name":"geographical origin","score":0.6700000166893005},{"id":"https://openalex.org/keywords/bioactive-compounds","display_name":"bioactive compounds","score":0.625},{"id":"https://openalex.org/keywords/hplc-uv-method-development","display_name":"HPLC-UV method development","score":0.6299999952316284}],"concepts":[{"id":"https://openalex.org/C134550120","wikidata":"https://www.wikidata.org/wiki/Q184208","display_name":"Rhizome","level":2,"score":0.7906985878944397},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.6774992346763611},{"id":"https://openalex.org/C179998833","wikidata":"https://www.wikidata.org/wiki/Q381233","display_name":"High-performance liquid chromatography","level":2,"score":0.6378623247146606},{"id":"https://openalex.org/C10390740","wikidata":"https://www.wikidata.org/wiki/Q2282401","display_name":"Analyte","level":2,"score":0.5793534517288208},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.559686541557312},{"id":"https://openalex.org/C119128265","wikidata":"https://www.wikidata.org/wiki/Q900165","display_name":"Detection limit","level":2,"score":0.4414416253566742},{"id":"https://openalex.org/C160437614","wikidata":"https://www.wikidata.org/wiki/Q3404720","display_name":"Tincture (heraldry)","level":2,"score":0.4192661643028259},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.11792528629302979},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.09924179315567017},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.08811730146408081},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1016/j.apsb.2013.08.003","doi":"https://doi.org/10.1016/j.apsb.2013.08.003","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.apsb.2013.08.003","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2211383513000798/pdf","source":{"id":"https://openalex.org/S2736993989","display_name":"Acta Pharmaceutica Sinica B","issn_l":"2211-3835","issn":["2211-3835","2211-3843"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-140"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Pharmaceutica Sinica B","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:fa5d9f17890444b8b6aa64f895e28edd","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/fa5d9f17890444b8b6aa64f895e28edd","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Acta Pharmaceutica Sinica B, Vol 3, Iss 5, Pp 354-360 (2013)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.apsb.2013.08.003","doi":"https://doi.org/10.1016/j.apsb.2013.08.003","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.apsb.2013.08.003","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2211383513000798/pdf","source":{"id":"https://openalex.org/S2736993989","display_name":"Acta Pharmaceutica Sinica B","issn_l":"2211-3835","issn":["2211-3835","2211-3843"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-140"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Pharmaceutica Sinica B","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2088055680.pdf","grobid_xml":"https://content.openalex.org/works/W2088055680.grobid-xml"},"referenced_works_count":12,"referenced_works":["https://openalex.org/W1969437584","https://openalex.org/W1972862281","https://openalex.org/W2010334374","https://openalex.org/W2022354772","https://openalex.org/W2024192736","https://openalex.org/W2050164570","https://openalex.org/W2074438210","https://openalex.org/W2088859888","https://openalex.org/W2089562281","https://openalex.org/W2105740841","https://openalex.org/W2825043698","https://openalex.org/W2951609297"],"related_works":["https://openalex.org/W2088859888","https://openalex.org/W2790516787","https://openalex.org/W1976433206","https://openalex.org/W7097933393","https://openalex.org/W4206212921","https://openalex.org/W2316688493","https://openalex.org/W2011650948","https://openalex.org/W2388856054","https://openalex.org/W4286703706","https://openalex.org/W4205847531"],"abstract_inverted_index":{"A":[0],"high-performance":[1],"liquid":[2],"chromatography":[3],"coupled":[4],"with":[5],"variable":[6],"wavelength":[7],"detection":[8,60],"(HPLC\u2013UV)":[9],"was":[10,125,144],"developed":[11],"to":[12],"evaluate":[13],"the":[14,41,50,66,81,89,92,103,106,133,158,172],"quality":[15],"of":[16,24,59,63,65,80,105,114,120,132,137,162,189],"Petasites":[17],"tatewakianus":[18,116,167],"Kitam":[19],"through":[20],"a":[21,37,54,181],"simultaneous":[22],"determination":[23],"eight":[25,42,107],"bakkenolides:":[26],"bakkenolide-L,":[27],"bakkenolide-D,":[28],"bakkenolide-B,":[29],"bakkenolide-Ia,":[30],"bakkenolide-VIIa,":[31],"bakkenolide-IVa,":[32],"bakkenolide-IIIa":[33],"and":[34,61,71,77,112,165,187],"homofukinolide.":[35],"With":[36],"C18":[38],"analytical":[39],"column,":[40],"analytes":[43,94],"were":[44,83,98],"efficiently":[45],"separated":[46],"using":[47],"tetrahydrofuran\u2013acetonitrile\u2013water":[48],"as":[49,180],"mobile":[51],"phase":[52],"in":[53,109,123,129,140,148],"constant":[55],"program.":[56],"The":[57,75,118,135,151],"limits":[58,62],"quantitation":[64],"method":[67,82],"ranged":[68,95],"0.42\u20132.56":[69],"\u03bcg/mL":[70],"1.22\u20138.40":[72],"\u03bcg/mL,":[73],"respectively.":[74],"intra-":[76],"inter-day":[78],"precisions":[79],"all":[84],"less":[85],"than":[86,127,146],"1.83%.":[87],"All":[88],"recoveries":[90],"for":[91,184],"spiked":[93],"97.8%\u2013102.4%.":[96],"There":[97],"statistically":[99],"significant":[100],"differences":[101],"among":[102],"contents":[104],"bakkenolides":[108,122,139],"different":[110],"parts":[111,131],"origins":[113],"P.":[115,163,166],"(P<0.01).":[117],"content":[119,136],"total":[121,138],"rhizome":[124,141,155],"higher":[126,145],"that":[128,154],"other":[130,149],"plant.":[134,191],"from":[142,168],"Baishan":[143,169],"those":[147],"localities.":[150],"result":[152],"suggested":[153],"may":[156,170],"be":[157,171],"most":[159],"valuable":[160],"part":[161],"tatewakianus,":[164],"best":[173],"plant":[174],"resource.":[175],"Our":[176],"results":[177],"might":[178],"serve":[179],"sound":[182],"foundation":[183],"further":[185],"study":[186],"application":[188],"this":[190]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2017,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}