{"id":"https://openalex.org/W2087936282","doi":"https://doi.org/10.1038/ki.1972.62","title":"Effect of urinary extracts from salt-loaded man on urinary sodium excretion by the rat","display_name":"Effect of urinary extracts from salt-loaded man on urinary sodium excretion by the rat","publication_year":1972,"publication_date":"1972-07-01","ids":{"openalex":"https://openalex.org/W2087936282","doi":"https://doi.org/10.1038/ki.1972.62","mag":"2087936282","pmid":"https://pubmed.ncbi.nlm.nih.gov/4671525"},"language":"en","primary_location":{"id":"doi:10.1038/ki.1972.62","doi":"https://doi.org/10.1038/ki.1972.62","is_oa":true,"landing_page_url":"https://doi.org/10.1038/ki.1972.62","pdf_url":"https://www.kidney-international.org/article/S0085-2538(15)31061-9/pdf","source":{"id":"https://openalex.org/S97303050","display_name":"Kidney International","issn_l":"0085-2538","issn":["0085-2538","1523-1755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-3","ki-jl-3","medline","norway-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kidney International","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.kidney-international.org/article/S0085-2538(15)31061-9/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103039781","display_name":"Peter Brown","orcid":"https://orcid.org/0000-0001-5894-8329","observed_orcids":["https://orcid.org/0000-0001-5894-8329"]},"institutions":[{"id":"https://openalex.org/I2802369498","display_name":"Charing Cross Hospital","ror":"https://ror.org/02gcp3110","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I153355300","https://openalex.org/I2802369498"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Peter R. Brown","raw_affiliation_strings":["Department of Medicine, Charing Cross Hospital Medical School, Fulham Hospital, London, England"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Charing Cross Hospital Medical School, Fulham Hospital, London, England","institution_ids":["https://openalex.org/I2802369498"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084562980","display_name":"Kosta G. Koutsaimanis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802369498","display_name":"Charing Cross Hospital","ror":"https://ror.org/02gcp3110","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I153355300","https://openalex.org/I2802369498"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Kosta G. Koutsaimanis","raw_affiliation_strings":["Department of Medicine, Charing Cross Hospital Medical School, Fulham Hospital, London, England"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Charing Cross Hospital Medical School, Fulham Hospital, London, England","institution_ids":["https://openalex.org/I2802369498"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082973339","display_name":"Hugh E. de Wardener","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802369498","display_name":"Charing Cross Hospital","ror":"https://ror.org/02gcp3110","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I153355300","https://openalex.org/I2802369498"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Hugh E. de Wardener","raw_affiliation_strings":["Department of Medicine, Charing Cross Hospital Medical School, Fulham Hospital, London, England"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Charing Cross Hospital Medical School, Fulham Hospital, London, England","institution_ids":["https://openalex.org/I2802369498"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I2802369498"],"apc_list":{"value":3500,"currency":"USD","value_usd":3500},"apc_paid":null,"fwci":6.4667,"has_fulltext":true,"cited_by_count":1729,"citation_normalized_percentile":{"value":0.96841732,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":"2","issue":"1","first_page":"1","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12075","display_name":"Sodium Intake and Health","score":0.951200008392334,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12075","display_name":"Sodium Intake and Health","score":0.951200008392334,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.017500000074505806,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11967","display_name":"Electrolyte and hormonal disorders","score":0.01549999974668026,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sodium-chloride-loading","display_name":"sodium chloride loading","score":0.6179999709129333},{"id":"https://openalex.org/keywords/sodium-excretion","display_name":"sodium excretion","score":0.9359999895095825},{"id":"https://openalex.org/keywords/urinary-flow","display_name":"urine flow","score":0.7770000100135803},{"id":"https://openalex.org/keywords/salt-depletion","display_name":"salt depletion","score":0.6959999799728394},{"id":"https://openalex.org/keywords/human-urine","display_name":"human urine","score":0.42399999499320984}],"concepts":[{"id":"https://openalex.org/C77411442","wikidata":"https://www.wikidata.org/wiki/Q181100","display_name":"Urinary system","level":2,"score":0.7525957822799683},{"id":"https://openalex.org/C10146269","wikidata":"https://www.wikidata.org/wiki/Q185557","display_name":"Excretion","level":2,"score":0.5822368264198303},{"id":"https://openalex.org/C537181965","wikidata":"https://www.wikidata.org/wiki/Q658","display_name":"Sodium","level":2,"score":0.5630600452423096},{"id":"https://openalex.org/C2776371256","wikidata":"https://www.wikidata.org/wiki/Q12370","display_name":"Salt (chemistry)","level":2,"score":0.5143743753433228},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.4716576635837555},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.43893831968307495},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.43770310282707214},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4253014922142029},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.42428550124168396},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.04796609282493591}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004039","descriptor_name":"Diet, Sodium-Restricted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004039","descriptor_name":"Diet, Sodium-Restricted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004039","descriptor_name":"Diet, Sodium-Restricted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009318","descriptor_name":"Natriuresis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009318","descriptor_name":"Natriuresis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009318","descriptor_name":"Natriuresis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D012964","descriptor_name":"Sodium","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false},{"descriptor_ui":"D012964","descriptor_name":"Sodium","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false},{"descriptor_ui":"D012964","descriptor_name":"Sodium","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false},{"descriptor_ui":"D012965","descriptor_name":"Sodium Chloride","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D012965","descriptor_name":"Sodium Chloride","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D012965","descriptor_name":"Sodium Chloride","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D014554","descriptor_name":"Urination","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D014554","descriptor_name":"Urination","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D014554","descriptor_name":"Urination","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D014556","descriptor_name":"Urine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014556","descriptor_name":"Urine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014556","descriptor_name":"Urine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014867","descriptor_name":"Water","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014867","descriptor_name":"Water","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014867","descriptor_name":"Water","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1038/ki.1972.62","doi":"https://doi.org/10.1038/ki.1972.62","is_oa":true,"landing_page_url":"https://doi.org/10.1038/ki.1972.62","pdf_url":"https://www.kidney-international.org/article/S0085-2538(15)31061-9/pdf","source":{"id":"https://openalex.org/S97303050","display_name":"Kidney International","issn_l":"0085-2538","issn":["0085-2538","1523-1755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-3","ki-jl-3","medline","norway-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kidney International","raw_type":"journal-article"},{"id":"pmid:4671525","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/4671525","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kidney international","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1038/ki.1972.62","doi":"https://doi.org/10.1038/ki.1972.62","is_oa":true,"landing_page_url":"https://doi.org/10.1038/ki.1972.62","pdf_url":"https://www.kidney-international.org/article/S0085-2538(15)31061-9/pdf","source":{"id":"https://openalex.org/S97303050","display_name":"Kidney International","issn_l":"0085-2538","issn":["0085-2538","1523-1755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-3","ki-jl-3","medline","norway-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kidney International","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.6240000128746033,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.5400000214576721,"display_name":"Clean water and sanitation","id":"https://metadata.un.org/sdg/6"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2087936282.pdf","grobid_xml":"https://content.openalex.org/works/W2087936282.grobid-xml"},"referenced_works_count":19,"referenced_works":["https://openalex.org/W1964581299","https://openalex.org/W1968990622","https://openalex.org/W1991923538","https://openalex.org/W2015065096","https://openalex.org/W2020030797","https://openalex.org/W2074434098","https://openalex.org/W2082929614","https://openalex.org/W2110424243","https://openalex.org/W2139621902","https://openalex.org/W2300487180","https://openalex.org/W2346182446","https://openalex.org/W2366686683","https://openalex.org/W2412616157","https://openalex.org/W2414951349","https://openalex.org/W2415236462","https://openalex.org/W2417977502","https://openalex.org/W4230180988","https://openalex.org/W4238251438","https://openalex.org/W4239841167"],"related_works":["https://openalex.org/W2355297220","https://openalex.org/W200904310","https://openalex.org/W1983751608","https://openalex.org/W1814249237","https://openalex.org/W1972632780","https://openalex.org/W2078679582","https://openalex.org/W2080563441","https://openalex.org/W2050968058","https://openalex.org/W2022011804","https://openalex.org/W1962754591"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2021,"cited_by_count":281},{"year":2020,"cited_by_count":268},{"year":2019,"cited_by_count":200},{"year":2018,"cited_by_count":187},{"year":2017,"cited_by_count":248},{"year":2016,"cited_by_count":162},{"year":2015,"cited_by_count":151},{"year":2014,"cited_by_count":108},{"year":2013,"cited_by_count":59},{"year":2012,"cited_by_count":27}],"updated_date":"2026-09-25T08:18:29.962427","created_date":"2025-10-10T00:00:00"}