{"id":"https://openalex.org/W2087655403","doi":"https://doi.org/10.1161/circulationaha.112.096156","title":"Trends in Antihypertensive Medication Use and Blood Pressure Control Among United States Adults With Hypertension","display_name":"Trends in Antihypertensive Medication Use and Blood Pressure Control Among United States Adults With Hypertension","publication_year":2012,"publication_date":"2012-10-22","ids":{"openalex":"https://openalex.org/W2087655403","doi":"https://doi.org/10.1161/circulationaha.112.096156","mag":"2087655403","pmid":"https://pubmed.ncbi.nlm.nih.gov/23091084"},"language":"en","primary_location":{"id":"doi:10.1161/circulationaha.112.096156","doi":"https://doi.org/10.1161/circulationaha.112.096156","is_oa":true,"landing_page_url":"https://doi.org/10.1161/circulationaha.112.096156","pdf_url":"https://www.ahajournals.org/doi/pdf/10.1161/CIRCULATIONAHA.112.096156","source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.ahajournals.org/doi/pdf/10.1161/CIRCULATIONAHA.112.096156","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034440996","display_name":"Qiuping Gu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1289490764","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934"]},{"id":"https://openalex.org/I1330589705","display_name":"National Center for Health Statistics","ror":"https://ror.org/03p15s250","country_code":"US","type":"other","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934","https://openalex.org/I1330589705"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Qiuping Gu","raw_affiliation_strings":["From the National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD","institution_ids":["https://openalex.org/I1289490764","https://openalex.org/I1330589705"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110025747","display_name":"Vicki L. Burt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1289490764","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934"]},{"id":"https://openalex.org/I1330589705","display_name":"National Center for Health Statistics","ror":"https://ror.org/03p15s250","country_code":"US","type":"other","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934","https://openalex.org/I1330589705"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vicki L. Burt","raw_affiliation_strings":["From the National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD","institution_ids":["https://openalex.org/I1289490764","https://openalex.org/I1330589705"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056877766","display_name":"Charles F. Dillon","orcid":"https://orcid.org/0009-0002-0621-0175","observed_orcids":["https://orcid.org/0009-0002-0621-0175"]},"institutions":[{"id":"https://openalex.org/I1289490764","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934"]},{"id":"https://openalex.org/I1330589705","display_name":"National Center for Health Statistics","ror":"https://ror.org/03p15s250","country_code":"US","type":"other","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934","https://openalex.org/I1330589705"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charles F. Dillon","raw_affiliation_strings":["From the National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD","institution_ids":["https://openalex.org/I1289490764","https://openalex.org/I1330589705"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5080245321","display_name":"Sarah Yoon","orcid":"https://orcid.org/0000-0002-5271-0296","observed_orcids":["https://orcid.org/0000-0002-5271-0296"]},"institutions":[{"id":"https://openalex.org/I1289490764","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934"]},{"id":"https://openalex.org/I1330589705","display_name":"National Center for Health Statistics","ror":"https://ror.org/03p15s250","country_code":"US","type":"other","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934","https://openalex.org/I1330589705"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sarah Yoon","raw_affiliation_strings":["From the National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD","institution_ids":["https://openalex.org/I1289490764","https://openalex.org/I1330589705"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":30.1302,"has_fulltext":true,"cited_by_count":529,"citation_normalized_percentile":{"value":0.99752406,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":100},"biblio":{"volume":"126","issue":"17","first_page":"2105","last_page":"2114"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12075","display_name":"Sodium Intake and Health","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.9079999923706055},{"id":"https://openalex.org/keywords/antihypertensive-medication-use","display_name":"antihypertensive medication use","score":0.9900000095367432},{"id":"https://openalex.org/keywords/blood-pressure-control","display_name":"blood pressure control","score":1.0},{"id":"https://openalex.org/keywords/combination-antihypertensive-therapy","display_name":"combination antihypertensive therapy","score":0.8629999756813049},{"id":"https://openalex.org/keywords/thiazide-diuretics","display_name":"thiazide diuretics","score":0.9190000295639038},{"id":"https://openalex.org/keywords/beta-blockers","display_name":"beta-blockers","score":0.9819999933242798},{"id":"https://openalex.org/keywords/ace-inhibitors","display_name":"ACE inhibitors","score":0.8090000152587891},{"id":"https://openalex.org/keywords/angiotensin-receptor-blockers","display_name":"angiotensin receptor blockers","score":0.9980000257492065},{"id":"https://openalex.org/keywords/mexican-americans","display_name":"Mexican Americans","score":0.6800000071525574},{"id":"https://openalex.org/keywords/racial-disparities","display_name":"racial disparities","score":0.7540000081062317},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.5139999985694885},{"id":"https://openalex.org/keywords/chronic-kidney-disease","display_name":"chronic kidney disease","score":0.9549999833106995},{"id":"https://openalex.org/keywords/cardiovascular-disease-prevention","display_name":"cardiovascular disease prevention","score":0.6909999847412109}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9617044925689697},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.7114089727401733},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4564717710018158},{"id":"https://openalex.org/C2780192228","wikidata":"https://www.wikidata.org/wiki/Q575890","display_name":"Antihypertensive drug","level":3,"score":0.41952091455459595},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3982464671134949},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.33299699425697327}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000959","descriptor_name":"Antihypertensive Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004359","descriptor_name":"Drug Therapy, Combination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009749","descriptor_name":"Nutrition Surveys","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":true},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1161/circulationaha.112.096156","doi":"https://doi.org/10.1161/circulationaha.112.096156","is_oa":true,"landing_page_url":"https://doi.org/10.1161/circulationaha.112.096156","pdf_url":"https://www.ahajournals.org/doi/pdf/10.1161/CIRCULATIONAHA.112.096156","source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation","raw_type":"journal-article"},{"id":"pmid:23091084","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23091084","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1161/circulationaha.112.096156","doi":"https://doi.org/10.1161/circulationaha.112.096156","is_oa":true,"landing_page_url":"https://doi.org/10.1161/circulationaha.112.096156","pdf_url":"https://www.ahajournals.org/doi/pdf/10.1161/CIRCULATIONAHA.112.096156","source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332162","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2087655403.pdf","grobid_xml":"https://content.openalex.org/works/W2087655403.grobid-xml"},"referenced_works_count":36,"referenced_works":["https://openalex.org/W77796725","https://openalex.org/W1496360905","https://openalex.org/W1968125938","https://openalex.org/W1973477276","https://openalex.org/W1980670470","https://openalex.org/W1998396678","https://openalex.org/W2012154384","https://openalex.org/W2013354239","https://openalex.org/W2033184572","https://openalex.org/W2043640056","https://openalex.org/W2058542140","https://openalex.org/W2064280397","https://openalex.org/W2073742622","https://openalex.org/W2076007231","https://openalex.org/W2079803188","https://openalex.org/W2112295862","https://openalex.org/W2117161260","https://openalex.org/W2120235169","https://openalex.org/W2122349429","https://openalex.org/W2127063773","https://openalex.org/W2132086081","https://openalex.org/W2137704829","https://openalex.org/W2143954917","https://openalex.org/W2144310433","https://openalex.org/W2156121263","https://openalex.org/W2158139785","https://openalex.org/W2160109513","https://openalex.org/W2160547085","https://openalex.org/W2166442548","https://openalex.org/W2166520734","https://openalex.org/W2297753288","https://openalex.org/W2330378155","https://openalex.org/W2404212513","https://openalex.org/W2562329777","https://openalex.org/W4285719527","https://openalex.org/W4300845335"],"related_works":["https://openalex.org/W2334143697","https://openalex.org/W3011410168","https://openalex.org/W2033184572","https://openalex.org/W4225961476","https://openalex.org/W4319748480","https://openalex.org/W3030178093","https://openalex.org/W4410463913","https://openalex.org/W7153593107","https://openalex.org/W2091991702","https://openalex.org/W2010023738"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,25,79],"monitoring":[2],"of":[3,18,27,56,81,109,121,157,170,176,251],"national":[4],"trends":[5,34],"in":[6,35,76,88,94,106],"hypertension":[7,189,211,237],"treatment":[8],"and":[9,39,67,128,137,146,153,174,201,229],"control":[10,45,232],"can":[11,248],"provide":[12],"important":[13],"insight":[14],"into":[15],"the":[16,64,107,119,163,241],"effectiveness":[17],"primary":[19],"prevention":[20],"efforts":[21],"for":[22],"cardiovascular":[23],"disease.":[24,206],"objective":[26],"this":[28,77],"study":[29],"was":[30,102],"to":[31,72,90,92,96,115,165,192,216],"examine":[32],"recent":[33],"antihypertensive":[36,82,111,218],"medication":[37,83,219,227],"use":[38,84,108,120,228],"its":[40],"impact":[41],"on":[42],"blood":[43,158,181,230,252],"pressure":[44,159,182,231,253],"among":[46,194,233],"US":[47,234],"adults":[48,235],"with":[49,142,151,203,210,223,236],"hypertension.":[50,224],"METHODS":[51],"AND":[52],"RESULTS:":[53],"A":[54],"total":[55],"9320":[57],"hypertensive":[58,172,178],"people":[59,173,179],"aged":[60],"\u226518":[61],"years":[62],"from":[63,86],"National":[65],"Health":[66],"Nutrition":[68],"Examination":[69],"Survey":[70],"2001":[71,89],"2010":[73,97,166],"were":[74,149,212],"included":[75],"study.":[78],"prevalence":[80],"increased":[85,132,155,239],"63.5%":[87],"2002":[91],"77.3%":[93],"2009":[95,164],"(P(trend)<0.01).":[98],"Most":[99],"notably,":[100],"there":[101],"a":[103],"large":[104],"increase":[105],"multiple":[110],"agents":[112],"(from":[113],"36.8%":[114],"47.7%,":[116],"P(trend)<0.01).":[117],"Overall,":[118],"thiazide":[122],"diuretics,":[123],"\u03b2-blockers,":[124],"angiotensin-converting":[125],"enzyme":[126],"inhibitors,":[127],"angiotensin":[129],"receptor":[130],"blockers":[131],"by":[133],"23%,":[134],"57%,":[135],"31%,":[136],"100%,":[138],"respectively.":[139,161],"In":[140],"comparison":[141],"monotherapy,":[143],"single-pill":[144],"combinations":[145,148],"multiple-pill":[147],"associated":[150],"55%":[152],"26%":[154],"likelihoods":[156],"control,":[160],"By":[162],"time":[167],"period,":[168],"47%":[169],"all":[171],"60%":[175],"treated":[177,186],"had":[180],"controlled.":[183],"However,":[184],"higher":[185],"but":[187],"uncontrolled":[188],"rates":[190],"continued":[191],"persist":[193],"older":[195],"Americans,":[196],"non-Hispanic":[197,221],"blacks,":[198],"diabetic":[199],"people,":[200],"those":[202],"chronic":[204],"kidney":[205],"Also,":[207],"Mexican":[208],"Americans":[209],"still":[213],"less":[214],"likely":[215],"take":[217],"than":[220],"whites":[222],"CONCLUSIONS:":[225],"Antihypertensive":[226],"significantly":[238],"over":[240],"past":[242],"10":[243],"years.":[244],"Combination":[245],"therapy":[246],"regimens":[247],"facilitate":[249],"achievement":[250],"goals.":[254]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":15},{"year":2024,"cited_by_count":24},{"year":2023,"cited_by_count":28},{"year":2022,"cited_by_count":20},{"year":2021,"cited_by_count":36},{"year":2020,"cited_by_count":51},{"year":2019,"cited_by_count":41},{"year":2018,"cited_by_count":54},{"year":2017,"cited_by_count":56},{"year":2016,"cited_by_count":50},{"year":2015,"cited_by_count":52},{"year":2014,"cited_by_count":55},{"year":2013,"cited_by_count":38},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}