{"id":"https://openalex.org/W2087640820","doi":"https://doi.org/10.1007/s11899-014-0202-9","title":"Novel Antibody Therapy in Acute Lymphoblastic Leukemia","display_name":"Novel Antibody Therapy in Acute Lymphoblastic Leukemia","publication_year":2014,"publication_date":"2014-03-12","ids":{"openalex":"https://openalex.org/W2087640820","doi":"https://doi.org/10.1007/s11899-014-0202-9","mag":"2087640820","pmid":"https://pubmed.ncbi.nlm.nih.gov/24623281"},"language":"en","primary_location":{"id":"doi:10.1007/s11899-014-0202-9","doi":"https://doi.org/10.1007/s11899-014-0202-9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11899-014-0202-9","pdf_url":null,"source":{"id":"https://openalex.org/S35022943","display_name":"Current Hematologic Malignancy Reports","issn_l":"1558-8211","issn":["1558-8211","1558-822X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Hematologic Malignancy Reports","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043633072","display_name":"Samith Thomas Kochuparambil","orcid":"https://orcid.org/0009-0003-2189-7304","observed_orcids":["https://orcid.org/0009-0003-2189-7304"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Samith T. Kochuparambil","raw_affiliation_strings":["Division of Hematology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA, kochuparambil.samith@mayo.edu","Mayo Clinic;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA, kochuparambil.samith@mayo.edu","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Mayo Clinic;","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085360755","display_name":"Mark Robert Litzow","orcid":"https://orcid.org/0000-0002-9816-6302","observed_orcids":["https://orcid.org/0000-0002-9816-6302"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Mark R. Litzow","raw_affiliation_strings":["Division of Hematology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA","Mayo Clinic;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Mayo Clinic;","institution_ids":["https://openalex.org/I1330342723"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5085360755"],"corresponding_institution_ids":["https://openalex.org/I1330342723"],"apc_list":{"value":3790,"currency":"USD","value_usd":3790},"apc_paid":null,"fwci":0.3054,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.2992278,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"9","issue":"2","first_page":"165","last_page":"173"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10950","display_name":"Acute Lymphoblastic Leukemia research","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10950","display_name":"Acute Lymphoblastic Leukemia research","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11491","display_name":"CAR-T cell therapy research","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11157","display_name":"Chronic Lymphocytic Leukemia Research","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acute-lymphoblastic-leukemia","display_name":"acute lymphoblastic leukemia","score":0.9750000238418579},{"id":"https://openalex.org/keywords/adult-acute-lymphoblastic-leukemia","display_name":"adult acute lymphoblastic leukemia","score":0.6819999814033508},{"id":"https://openalex.org/keywords/monoclonal-antibody-therapy","display_name":"monoclonal antibody therapy","score":0.9539999961853027},{"id":"https://openalex.org/keywords/rituximab","display_name":"rituximab","score":0.8640000224113464},{"id":"https://openalex.org/keywords/anti-cd20-monoclonal-antibody","display_name":"anti-CD20 monoclonal antibody","score":0.8169999718666077},{"id":"https://openalex.org/keywords/epratuzumab","display_name":"epratuzumab","score":0.8949999809265137},{"id":"https://openalex.org/keywords/anti-cd22-antibody","display_name":"anti-CD22 antibody","score":0.9210000038146973},{"id":"https://openalex.org/keywords/inotuzumab-ozogamicin","display_name":"inotuzumab ozogamicin","score":0.9509999752044678},{"id":"https://openalex.org/keywords/blinatumomab","display_name":"blinatumomab","score":0.7900000214576721},{"id":"https://openalex.org/keywords/bispecific-t-cell-engagers","display_name":"bispecific T-cell engagers","score":0.9010000228881836},{"id":"https://openalex.org/keywords/car-t-cell-therapy","display_name":"CAR T-cell therapy","score":0.8759999871253967},{"id":"https://openalex.org/keywords/relapsed-refractory-all","display_name":"relapsed/refractory ALL","score":0.7390000224113464},{"id":"https://openalex.org/keywords/treatment-related-toxicity","display_name":"treatment toxicity","score":0.4020000100135803}],"concepts":[{"id":"https://openalex.org/C2778020697","wikidata":"https://www.wikidata.org/wiki/Q410189","display_name":"Blinatumomab","level":4,"score":0.9353975057601929},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8481338024139404},{"id":"https://openalex.org/C2780653079","wikidata":"https://www.wikidata.org/wiki/Q412323","display_name":"Rituximab","level":3,"score":0.6898637413978577},{"id":"https://openalex.org/C111700020","wikidata":"https://www.wikidata.org/wiki/Q5009798","display_name":"CD22","level":4,"score":0.6482260823249817},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.609481692314148},{"id":"https://openalex.org/C3875195","wikidata":"https://www.wikidata.org/wiki/Q5099363","display_name":"Chimeric antigen receptor","level":4,"score":0.5682932138442993},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5348267555236816},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.49593886733055115},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.4693390429019928},{"id":"https://openalex.org/C194409129","wikidata":"https://www.wikidata.org/wiki/Q103824","display_name":"Hematology","level":2,"score":0.4658893644809723},{"id":"https://openalex.org/C2778623314","wikidata":"https://www.wikidata.org/wiki/Q412685","display_name":"Gemtuzumab ozogamicin","level":5,"score":0.45014482736587524},{"id":"https://openalex.org/C142424586","wikidata":"https://www.wikidata.org/wiki/Q7307572","display_name":"Refractory (planetary science)","level":2,"score":0.42919477820396423},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.414445161819458},{"id":"https://openalex.org/C18031839","wikidata":"https://www.wikidata.org/wiki/Q5009796","display_name":"CD20","level":3,"score":0.4137061536312103},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.31435465812683105},{"id":"https://openalex.org/C2778957590","wikidata":"https://www.wikidata.org/wiki/Q798033","display_name":"CD19","level":3,"score":0.18983080983161926},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.1777043640613556},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.14995625615119934},{"id":"https://openalex.org/C176290653","wikidata":"https://www.wikidata.org/wiki/Q21114013","display_name":"CD33","level":4,"score":0.12468644976615906},{"id":"https://openalex.org/C87355193","wikidata":"https://www.wikidata.org/wiki/Q411","display_name":"Astrobiology","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C10205521","wikidata":"https://www.wikidata.org/wiki/Q4035578","display_name":"CD34","level":3,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D002986","descriptor_name":"Clinical Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007167","descriptor_name":"Immunotherapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D054198","descriptor_name":"Precursor Cell Lymphoblastic Leukemia-Lymphoma","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D058990","descriptor_name":"Molecular Targeted Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1007/s11899-014-0202-9","doi":"https://doi.org/10.1007/s11899-014-0202-9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11899-014-0202-9","pdf_url":null,"source":{"id":"https://openalex.org/S35022943","display_name":"Current Hematologic Malignancy Reports","issn_l":"1558-8211","issn":["1558-8211","1558-822X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Hematologic Malignancy Reports","raw_type":"journal-article"},{"id":"pmid:24623281","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24623281","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current hematologic malignancy reports","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":55,"referenced_works":["https://openalex.org/W1488000644","https://openalex.org/W1689607850","https://openalex.org/W1772206618","https://openalex.org/W1948401147","https://openalex.org/W1963592300","https://openalex.org/W1975280591","https://openalex.org/W1991644988","https://openalex.org/W1994482907","https://openalex.org/W1999624685","https://openalex.org/W2005395372","https://openalex.org/W2016833582","https://openalex.org/W2018071905","https://openalex.org/W2026177698","https://openalex.org/W2031452426","https://openalex.org/W2038414910","https://openalex.org/W2054025347","https://openalex.org/W2066064966","https://openalex.org/W2067087822","https://openalex.org/W2067585473","https://openalex.org/W2068808678","https://openalex.org/W2072428030","https://openalex.org/W2076890670","https://openalex.org/W2082189475","https://openalex.org/W2096649209","https://openalex.org/W2105400883","https://openalex.org/W2115948410","https://openalex.org/W2120104555","https://openalex.org/W2122921932","https://openalex.org/W2123755151","https://openalex.org/W2124575836","https://openalex.org/W2126855868","https://openalex.org/W2127742735","https://openalex.org/W2128272164","https://openalex.org/W2128491464","https://openalex.org/W2130338247","https://openalex.org/W2132059723","https://openalex.org/W2143749371","https://openalex.org/W2151177887","https://openalex.org/W2159877301","https://openalex.org/W2164006259","https://openalex.org/W2298308371","https://openalex.org/W2460477750","https://openalex.org/W2462869396","https://openalex.org/W2558541011","https://openalex.org/W2564975221","https://openalex.org/W2566007460","https://openalex.org/W2583392141","https://openalex.org/W2587131006","https://openalex.org/W2587196231","https://openalex.org/W2592766491","https://openalex.org/W2592851172","https://openalex.org/W2782401160","https://openalex.org/W2979407177","https://openalex.org/W2979542748","https://openalex.org/W4255309549"],"related_works":["https://openalex.org/W2010562953","https://openalex.org/W2115948410","https://openalex.org/W2908115938","https://openalex.org/W2946805300","https://openalex.org/W2026698098","https://openalex.org/W2055401871","https://openalex.org/W2087506557","https://openalex.org/W2166899683","https://openalex.org/W2070004244","https://openalex.org/W2075275816"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}