{"id":"https://openalex.org/W2087474656","doi":"https://doi.org/10.1016/s0022-3476(82)80633-1","title":"Serum hemolytic factor D values in children with steroid-responsive idiopathic nephrotic syndrome","display_name":"Serum hemolytic factor D values in children with steroid-responsive idiopathic nephrotic syndrome","publication_year":1982,"publication_date":"1982-02-01","ids":{"openalex":"https://openalex.org/W2087474656","doi":"https://doi.org/10.1016/s0022-3476(82)80633-1","mag":"2087474656","pmid":"https://pubmed.ncbi.nlm.nih.gov/6915968"},"language":"en","primary_location":{"id":"doi:10.1016/s0022-3476(82)80633-1","doi":"https://doi.org/10.1016/s0022-3476(82)80633-1","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0022-3476(82)80633-1","pdf_url":null,"source":{"id":"https://openalex.org/S3774022","display_name":"The Journal of Pediatrics","issn_l":"0022-3476","issn":["0022-3476","1085-8695","1097-6833"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Pediatrics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037734477","display_name":"Mark C. Ballow","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]},{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]},{"id":"https://openalex.org/I75929689","display_name":"UConn Health","ror":"https://ror.org/02kzs4y22","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I75929689"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Mark Ballow","raw_affiliation_strings":["Department of Pediatrics, Johns Hopkins Hospital, Baltimore, Md., USA","Department of Pediatrics, University of Connecticut Health Center, School of Medicine, Farmington, Conn., USA","Department of Pediatrics, Yale University School of Medicine, New Haven, Conn., USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Johns Hopkins Hospital, Baltimore, Md., USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]},{"raw_affiliation_string":"Department of Pediatrics, University of Connecticut Health Center, School of Medicine, Farmington, Conn., USA","institution_ids":["https://openalex.org/I75929689"]},{"raw_affiliation_string":"Department of Pediatrics, Yale University School of Medicine, New Haven, Conn., USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Thomas L. Kennedy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]},{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]},{"id":"https://openalex.org/I75929689","display_name":"UConn Health","ror":"https://ror.org/02kzs4y22","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I75929689"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas L. Kennedy","raw_affiliation_strings":["Department of Pediatrics, Johns Hopkins Hospital, Baltimore, Md., USA","Department of Pediatrics, University of Connecticut Health Center, School of Medicine, Farmington, Conn., USA","Department of Pediatrics, Yale University School of Medicine, New Haven, Conn., USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Johns Hopkins Hospital, Baltimore, Md., USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]},{"raw_affiliation_string":"Department of Pediatrics, University of Connecticut Health Center, School of Medicine, Farmington, Conn., USA","institution_ids":["https://openalex.org/I75929689"]},{"raw_affiliation_string":"Department of Pediatrics, Yale University School of Medicine, New Haven, Conn., USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113434233","display_name":"Karen M. Gaudio","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]},{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]},{"id":"https://openalex.org/I75929689","display_name":"UConn Health","ror":"https://ror.org/02kzs4y22","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I75929689"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Karen M. Gaudio","raw_affiliation_strings":["Department of Pediatrics, Johns Hopkins Hospital, Baltimore, Md., USA","Department of Pediatrics, University of Connecticut Health Center, School of Medicine, Farmington, Conn., USA","Department of Pediatrics, Yale University School of Medicine, New Haven, Conn., USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Johns Hopkins Hospital, Baltimore, Md., USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]},{"raw_affiliation_string":"Department of Pediatrics, University of Connecticut Health Center, School of Medicine, Farmington, Conn., USA","institution_ids":["https://openalex.org/I75929689"]},{"raw_affiliation_string":"Department of Pediatrics, Yale University School of Medicine, New Haven, Conn., USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031476322","display_name":"Norman J. Siegel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]},{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]},{"id":"https://openalex.org/I75929689","display_name":"UConn Health","ror":"https://ror.org/02kzs4y22","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I75929689"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Norman J. Siegel","raw_affiliation_strings":["Department of Pediatrics, Johns Hopkins Hospital, Baltimore, Md., USA","Department of Pediatrics, University of Connecticut Health Center, School of Medicine, Farmington, Conn., USA","Department of Pediatrics, Yale University School of Medicine, New Haven, Conn., USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Johns Hopkins Hospital, Baltimore, Md., USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]},{"raw_affiliation_string":"Department of Pediatrics, University of Connecticut Health Center, School of Medicine, Farmington, Conn., USA","institution_ids":["https://openalex.org/I75929689"]},{"raw_affiliation_string":"Department of Pediatrics, Yale University School of Medicine, New Haven, Conn., USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110037358","display_name":"Robert H. McLean","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]},{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]},{"id":"https://openalex.org/I75929689","display_name":"UConn Health","ror":"https://ror.org/02kzs4y22","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I75929689"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert H. McLean","raw_affiliation_strings":["Department of Pediatrics, Johns Hopkins Hospital, Baltimore, Md., USA","Department of Pediatrics, University of Connecticut Health Center, School of Medicine, Farmington, Conn., USA","Department of Pediatrics, Yale University School of Medicine, New Haven, Conn., USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Johns Hopkins Hospital, Baltimore, Md., USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]},{"raw_affiliation_string":"Department of Pediatrics, University of Connecticut Health Center, School of Medicine, Farmington, Conn., USA","institution_ids":["https://openalex.org/I75929689"]},{"raw_affiliation_string":"Department of Pediatrics, Yale University School of Medicine, New Haven, Conn., USA","institution_ids":["https://openalex.org/I32971472"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5037734477"],"corresponding_institution_ids":["https://openalex.org/I145311948","https://openalex.org/I32971472","https://openalex.org/I4210150714","https://openalex.org/I75929689"],"apc_list":{"value":4570,"currency":"USD","value_usd":4570},"apc_paid":null,"fwci":0.5126,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.68447082,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"100","issue":"2","first_page":"192","last_page":"196"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11029","display_name":"Renal Diseases and Glomerulopathies","score":0.8589000105857849,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11029","display_name":"Renal Diseases and Glomerulopathies","score":0.8589000105857849,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10993","display_name":"Complement system in diseases","score":0.13439999520778656,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/idiopathic-nephrotic-syndrome","display_name":"idiopathic nephrotic syndrome","score":0.7689999938011169},{"id":"https://openalex.org/keywords/steroid-sensitive-nephrotic-syndrome","display_name":"steroid-sensitive nephrotic syndrome","score":0.9580000042915344},{"id":"https://openalex.org/keywords/alternative-complement-pathway","display_name":"alternative complement pathway","score":0.8199999928474426},{"id":"https://openalex.org/keywords/complement-activation","display_name":"complement activation","score":0.6340000033378601},{"id":"https://openalex.org/keywords/recurrence","display_name":"recurrence","score":0.7409999966621399},{"id":"https://openalex.org/keywords/serum-albumin","display_name":"serum albumin","score":0.9229999780654907},{"id":"https://openalex.org/keywords/bacterial-infection-susceptibility","display_name":"bacterial infection susceptibility","score":0.9039999842643738},{"id":"https://openalex.org/keywords/children","display_name":"children","score":0.48500001430511475}],"concepts":[{"id":"https://openalex.org/C2778930706","wikidata":"https://www.wikidata.org/wiki/Q504790","display_name":"Nephrotic syndrome","level":2,"score":0.8060219287872314},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8043556213378906},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7642070055007935},{"id":"https://openalex.org/C2910035153","wikidata":"https://www.wikidata.org/wiki/Q504790","display_name":"Idiopathic Nephrotic Syndrome","level":4,"score":0.738095760345459},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.588087260723114},{"id":"https://openalex.org/C165616093","wikidata":"https://www.wikidata.org/wiki/Q424232","display_name":"Serum albumin","level":2,"score":0.5534390211105347},{"id":"https://openalex.org/C2776125364","wikidata":"https://www.wikidata.org/wiki/Q169219","display_name":"Albumin","level":2,"score":0.5460165143013},{"id":"https://openalex.org/C182629451","wikidata":"https://www.wikidata.org/wiki/Q18251054","display_name":"Complement factor B","level":4,"score":0.43022334575653076},{"id":"https://openalex.org/C2780026642","wikidata":"https://www.wikidata.org/wiki/Q40924","display_name":"Urine","level":2,"score":0.4229053854942322},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3062664270401001},{"id":"https://openalex.org/C2779561371","wikidata":"https://www.wikidata.org/wiki/Q570197","display_name":"Proteinuria","level":3,"score":0.18659144639968872},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.13042905926704407},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.1183834969997406},{"id":"https://openalex.org/C111684460","wikidata":"https://www.wikidata.org/wiki/Q334848","display_name":"Complement system","level":3,"score":0.05995762348175049}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003166","descriptor_name":"Complement Activating Enzymes","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D003167","descriptor_name":"Complement Activation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007674","descriptor_name":"Kidney Diseases","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D009404","descriptor_name":"Nephrotic Syndrome","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D011416","descriptor_name":"Complement Factor D","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012709","descriptor_name":"Serum Albumin","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0022-3476(82)80633-1","doi":"https://doi.org/10.1016/s0022-3476(82)80633-1","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0022-3476(82)80633-1","pdf_url":null,"source":{"id":"https://openalex.org/S3774022","display_name":"The Journal of Pediatrics","issn_l":"0022-3476","issn":["0022-3476","1085-8695","1097-6833"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Pediatrics","raw_type":"journal-article"},{"id":"pmid:6915968","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6915968","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of pediatrics","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","score":0.8199999928474426,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W207980350","https://openalex.org/W322480053","https://openalex.org/W1511988600","https://openalex.org/W1538282929","https://openalex.org/W1853641470","https://openalex.org/W1891305534","https://openalex.org/W1980147648","https://openalex.org/W1987659315","https://openalex.org/W1987810250","https://openalex.org/W2001176043","https://openalex.org/W2014889564","https://openalex.org/W2015003681","https://openalex.org/W2029166190","https://openalex.org/W2035412364","https://openalex.org/W2044764627","https://openalex.org/W2053832175","https://openalex.org/W2062424043","https://openalex.org/W2073349958","https://openalex.org/W2083143298","https://openalex.org/W2083376180","https://openalex.org/W2087265320","https://openalex.org/W2091559941","https://openalex.org/W2134493315","https://openalex.org/W2151098851","https://openalex.org/W2196702925","https://openalex.org/W2323798876","https://openalex.org/W2327263558","https://openalex.org/W2412544409","https://openalex.org/W2495042754","https://openalex.org/W4231203550","https://openalex.org/W4313311577"],"related_works":["https://openalex.org/W2094629305","https://openalex.org/W2083143298","https://openalex.org/W2327263558","https://openalex.org/W2746200863","https://openalex.org/W2116524865","https://openalex.org/W2761219431","https://openalex.org/W2409400982","https://openalex.org/W1979152005","https://openalex.org/W4416744250","https://openalex.org/W2122036544"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
