{"id":"https://openalex.org/W2087133148","doi":"https://doi.org/10.1006/excr.1999.4766","title":"Retinoic Acid-Induced blr1 Expression Promotes ERK2 Activation and Cell Differentiation in HL-60 Cells","display_name":"Retinoic Acid-Induced blr1 Expression Promotes ERK2 Activation and Cell Differentiation in HL-60 Cells","publication_year":2000,"publication_date":"2000-02-01","ids":{"openalex":"https://openalex.org/W2087133148","doi":"https://doi.org/10.1006/excr.1999.4766","mag":"2087133148","pmid":"https://pubmed.ncbi.nlm.nih.gov/10640427"},"language":"en","primary_location":{"id":"doi:10.1006/excr.1999.4766","doi":"https://doi.org/10.1006/excr.1999.4766","is_oa":true,"landing_page_url":"https://doi.org/10.1006/excr.1999.4766","pdf_url":null,"source":{"id":"https://openalex.org/S132505712","display_name":"Experimental Cell Research","issn_l":"0014-4827","issn":["0014-4827","1090-2422"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental Cell Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1006/excr.1999.4766","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015100500","display_name":"Traci E. Battle","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Traci E. Battle","raw_affiliation_strings":["Department of Biomedical Sciences, College of Veterinary Medicine, Ithaca, New York 14853, USA. traci_battle@dfci.harvard.edu","Department of Biomedical Sciences, College of Veterinary Medicine, Ithaca, New York 14853, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences, College of Veterinary Medicine, Ithaca, New York 14853, USA. traci_battle@dfci.harvard.edu","institution_ids":[]},{"raw_affiliation_string":"Department of Biomedical Sciences, College of Veterinary Medicine, Ithaca, New York 14853, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105793221","display_name":"Roy A. Levine","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4210151139","display_name":"New York State College of Veterinary Medicine","ror":"https://ror.org/04r17kf39","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4210151139"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Roy A. Levine","raw_affiliation_strings":["Cancer Biology Laboratories, Department of Molecular Medicine, College of Veterinary Medicine, Cornell University, Ithaca, New York, 14853"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Biology Laboratories, Department of Molecular Medicine, College of Veterinary Medicine, Cornell University, Ithaca, New York, 14853","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4210151139"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101621721","display_name":"Andrew Yen","orcid":"https://orcid.org/0000-0003-2094-4845","observed_orcids":["https://orcid.org/0000-0003-2094-4845"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4210151139","display_name":"New York State College of Veterinary Medicine","ror":"https://ror.org/04r17kf39","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4210151139"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew Yen","raw_affiliation_strings":["Cancer Biology Laboratories, Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, 14853"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Biology Laboratories, Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, 14853","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4210151139"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5015100500"],"corresponding_institution_ids":[],"apc_list":{"value":3270,"currency":"USD","value_usd":3270},"apc_paid":{"value":3270,"currency":"USD","value_usd":3270},"fwci":1.083,"has_fulltext":false,"cited_by_count":33,"citation_normalized_percentile":{"value":0.75603751,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"254","issue":"2","first_page":"287","last_page":"298"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11559","display_name":"Retinoids in leukemia and cellular processes","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11559","display_name":"Retinoids in leukemia and cellular processes","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11532","display_name":"Chemokine receptors and signaling","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/retinoic-acid","display_name":"retinoic acid","score":0.9490000009536743},{"id":"https://openalex.org/keywords/chemokine-receptors","display_name":"chemokine receptors","score":0.8880000114440918},{"id":"https://openalex.org/keywords/hl-60-cells","display_name":"HL-60 cells","score":0.9089999794960022},{"id":"https://openalex.org/keywords/promyelocytic-leukemia","display_name":"promyelocytic leukemia","score":0.8479999899864197},{"id":"https://openalex.org/keywords/myeloid-differentiation","display_name":"myeloid differentiation","score":0.8270000219345093},{"id":"https://openalex.org/keywords/g1-cell-cycle-arrest","display_name":"G1 cell cycle arrest","score":0.8690000176429749},{"id":"https://openalex.org/keywords/1-25-dihydroxyvitamin-d3","display_name":"1,25-dihydroxyvitamin D3","score":0.9259999990463257},{"id":"https://openalex.org/keywords/dimethyl-sulfoxide","display_name":"dimethyl sulfoxide","score":0.8339999914169312},{"id":"https://openalex.org/keywords/gene-expression-regulation","display_name":"gene expression regulation","score":0.6309999823570251},{"id":"https://openalex.org/keywords/retinoids","display_name":"retinoids","score":0.44999998807907104}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8500416278839111},{"id":"https://openalex.org/C2781121885","wikidata":"https://www.wikidata.org/wiki/Q425517","display_name":"Retinoic acid","level":3,"score":0.8188621997833252},{"id":"https://openalex.org/C89364313","wikidata":"https://www.wikidata.org/wiki/Q7316795","display_name":"Retinoic acid-inducible orphan G protein-coupled receptor","level":5,"score":0.6464898586273193},{"id":"https://openalex.org/C148738053","wikidata":"https://www.wikidata.org/wiki/Q210861","display_name":"Cellular differentiation","level":3,"score":0.6159964799880981},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.6008520722389221},{"id":"https://openalex.org/C19431177","wikidata":"https://www.wikidata.org/wiki/Q18031041","display_name":"Retinoic acid receptor beta","level":5,"score":0.5739389061927795},{"id":"https://openalex.org/C120197328","wikidata":"https://www.wikidata.org/wiki/Q2838685","display_name":"Retinoic acid receptor","level":4,"score":0.5367646813392639},{"id":"https://openalex.org/C139522298","wikidata":"https://www.wikidata.org/wiki/Q18031042","display_name":"Retinoic acid receptor gamma","level":5,"score":0.49268847703933716},{"id":"https://openalex.org/C119775778","wikidata":"https://www.wikidata.org/wiki/Q18031040","display_name":"Retinoic acid receptor alpha","level":5,"score":0.46837860345840454},{"id":"https://openalex.org/C2776601000","wikidata":"https://www.wikidata.org/wiki/Q612108","display_name":"Acute promyelocytic leukemia","level":4,"score":0.46660420298576355},{"id":"https://openalex.org/C2779963572","wikidata":"https://www.wikidata.org/wiki/Q29417","display_name":"Tretinoin","level":4,"score":0.45142048597335815},{"id":"https://openalex.org/C2778128677","wikidata":"https://www.wikidata.org/wiki/Q412895","display_name":"Cycloheximide","level":3,"score":0.4338943362236023},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.39381569623947144},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.3150259852409363},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.15222424268722534},{"id":"https://openalex.org/C3675279","wikidata":"https://www.wikidata.org/wiki/Q211935","display_name":"Protein biosynthesis","level":2,"score":0.12153413891792297},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.10977399349212646},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.07329097390174866}],"mesh":[{"descriptor_ui":"D002117","descriptor_name":"Calcitriol","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D002455","descriptor_name":"Cell Division","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D003513","descriptor_name":"Cycloheximide","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004121","descriptor_name":"Dimethyl Sulfoxide","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007938","descriptor_name":"Leukemia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008562","descriptor_name":"Membrane Glycoproteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014162","descriptor_name":"Transfection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014212","descriptor_name":"Tretinoin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D014407","descriptor_name":"Tumor Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016192","descriptor_name":"Resting Phase, Cell Cycle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016193","descriptor_name":"G1 Phase","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017398","descriptor_name":"Alternative Splicing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018121","descriptor_name":"Receptors, Cytokine","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D018121","descriptor_name":"Receptors, Cytokine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018922","descriptor_name":"HL-60 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019707","descriptor_name":"Receptors, Chemokine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019950","descriptor_name":"Mitogen-Activated Protein Kinase 1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D054380","descriptor_name":"Receptors, CXCR5","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1006/excr.1999.4766","doi":"https://doi.org/10.1006/excr.1999.4766","is_oa":true,"landing_page_url":"https://doi.org/10.1006/excr.1999.4766","pdf_url":null,"source":{"id":"https://openalex.org/S132505712","display_name":"Experimental Cell Research","issn_l":"0014-4827","issn":["0014-4827","1090-2422"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental Cell Research","raw_type":"journal-article"},{"id":"pmid:10640427","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10640427","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental cell research","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1006/excr.1999.4766","doi":"https://doi.org/10.1006/excr.1999.4766","is_oa":true,"landing_page_url":"https://doi.org/10.1006/excr.1999.4766","pdf_url":null,"source":{"id":"https://openalex.org/S132505712","display_name":"Experimental Cell Research","issn_l":"0014-4827","issn":["0014-4827","1090-2422"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental Cell Research","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.46810001134872437,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5241395156","display_name":null,"funder_award_id":"ESO7052","funder_id":"https://openalex.org/F4320337361","funder_display_name":"National Institute of Environmental Health Sciences"}],"funders":[{"id":"https://openalex.org/F4320337361","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":82,"referenced_works":["https://openalex.org/W83588186","https://openalex.org/W131204360","https://openalex.org/W144119440","https://openalex.org/W174661090","https://openalex.org/W324549396","https://openalex.org/W1482866022","https://openalex.org/W1511459507","https://openalex.org/W1538431955","https://openalex.org/W1554600230","https://openalex.org/W1561957470","https://openalex.org/W1567065545","https://openalex.org/W1570736076","https://openalex.org/W1587753655","https://openalex.org/W1588479784","https://openalex.org/W1594412667","https://openalex.org/W1595664534","https://openalex.org/W1607326348","https://openalex.org/W1625203433","https://openalex.org/W1636159574","https://openalex.org/W1795056021","https://openalex.org/W1903161793","https://openalex.org/W1918405313","https://openalex.org/W1955568895","https://openalex.org/W1966165057","https://openalex.org/W1966657425","https://openalex.org/W1967014008","https://openalex.org/W1970335311","https://openalex.org/W1975915718","https://openalex.org/W1978368163","https://openalex.org/W1986276041","https://openalex.org/W1989480480","https://openalex.org/W1995522877","https://openalex.org/W1995819749","https://openalex.org/W1997115870","https://openalex.org/W1998597651","https://openalex.org/W1998778584","https://openalex.org/W2011007863","https://openalex.org/W2011653196","https://openalex.org/W2012603529","https://openalex.org/W2022891913","https://openalex.org/W2025218436","https://openalex.org/W2032495611","https://openalex.org/W2042154282","https://openalex.org/W2047975134","https://openalex.org/W2049271109","https://openalex.org/W2059763373","https://openalex.org/W2060016377","https://openalex.org/W2063620931","https://openalex.org/W2070136321","https://openalex.org/W2076891314","https://openalex.org/W2085124463","https://openalex.org/W2088823687","https://openalex.org/W2089868362","https://openalex.org/W2090762224","https://openalex.org/W2105086102","https://openalex.org/W2114123652","https://openalex.org/W2117308812","https://openalex.org/W2130938952","https://openalex.org/W2150200572","https://openalex.org/W2156831114","https://openalex.org/W2219737146","https://openalex.org/W2293885897","https://openalex.org/W2319872820","https://openalex.org/W2327237185","https://openalex.org/W2407345634","https://openalex.org/W2409277110","https://openalex.org/W2410282023","https://openalex.org/W2410689766","https://openalex.org/W2411720213","https://openalex.org/W2417349563","https://openalex.org/W2433014878","https://openalex.org/W4205429959","https://openalex.org/W4237493484","https://openalex.org/W4241184938","https://openalex.org/W6603386123","https://openalex.org/W6632173044","https://openalex.org/W6636975307","https://openalex.org/W6639728690","https://openalex.org/W6683346201","https://openalex.org/W6714671646","https://openalex.org/W6715131051","https://openalex.org/W6718014892"],"related_works":["https://openalex.org/W2062114671","https://openalex.org/W1794519188","https://openalex.org/W2141083396","https://openalex.org/W1903161793","https://openalex.org/W1979163377","https://openalex.org/W1985610329","https://openalex.org/W969843666","https://openalex.org/W1039655981","https://openalex.org/W2065514457","https://openalex.org/W2171038620"],"abstract_inverted_index":{"Retinoids":[0],"are":[1,29,110],"known":[2],"to":[3,22,180],"induce":[4],"the":[5,44,136],"differentiation":[6,79,190],"and":[7,123,160,167,184],"cell":[8,168],"cycle":[9],"arrest":[10,83,166],"of":[11,43,72,89,99,126,151,173,187],"human":[12,34],"myeloid":[13],"leukemia":[14,36],"cells":[15,37,109,143],"in":[16,32,156,198],"vitro.":[17],"Differential":[18],"display":[19],"was":[20],"used":[21],"identify":[23],"putative":[24],"early":[25,171],"regulatory":[26,95],"genes":[27],"that":[28,64,192],"differentially":[30],"expressed":[31],"HL-60":[33,142,201],"promyelocytic":[35],"treated":[38],"with":[39,146],"retinoic":[40,73,130,162,188,199],"acid.":[41],"One":[42],"cDNAs":[45],"cloned":[46],"encodes":[47],"sequences":[48],"identifying":[49],"Burkitt's":[50],"lymphoma":[51],"receptor":[52],"1":[53],"(BLR1),":[54],"a":[55,93],"recently":[56],"described":[57],"chemokine":[58],"receptor.":[59],"Northern":[60],"blot":[61],"analysis":[62],"demonstrates":[63],"blr1":[65,100,112,127,147,152,174,193],"mRNA":[66,101,113,128,175],"expression":[67,98,150,172,194],"increases":[68],"within":[69],"9":[70],"h":[71,86,107],"acid":[74,131],"treatment,":[75],"well":[76],"before":[77],"functional":[78],"or":[80,87],"G(1)/G(0)":[81,164],"growth":[82,165],"at":[84,105],"48":[85],"onset":[88],"morphological":[90],"changes,":[91],"suggesting":[92],"possible":[94],"function.":[96],"The":[97,170],"is":[102,115,132],"transient,":[103],"peaking":[104],"72":[106],"when":[108],"differentiated.":[111],"also":[114],"induced":[116],"by":[117,129,135],"other":[118],"differentiation-inducing":[119],"agents,":[120],"1alpha,25-dihydroxyvitamin":[121],"D(3)":[122],"DMSO.":[124],"Induction":[125],"not":[133],"blocked":[134],"protein":[137],"synthesis":[138],"inhibitor":[139],"cycloheximide.":[140],"In":[141],"stably":[144],"transfected":[145],"cDNA,":[148],"ectopic":[149],"causes":[153],"an":[154],"increase":[155,181],"ERK2":[157,182],"MAPK":[158],"activation":[159],"promotes":[161],"acid-induced":[163,189,200],"differentiation.":[169,202],"during":[176],"differentiation,":[177],"its":[178,185],"ability":[179],"activation,":[183],"enhancement":[186],"suggest":[191],"may":[195],"be":[196],"involved":[197]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}