{"id":"https://openalex.org/W2086940950","doi":"https://doi.org/10.1016/j.carpath.2004.03.277","title":"INHIBITION OF STAT1 ACTIVITY INHIBITS FOAM CELL FORMATION IN MACROPHAGES","display_name":"INHIBITION OF STAT1 ACTIVITY INHIBITS FOAM CELL FORMATION IN MACROPHAGES","publication_year":2004,"publication_date":"2004-04-29","ids":{"openalex":"https://openalex.org/W2086940950","doi":"https://doi.org/10.1016/j.carpath.2004.03.277","mag":"2086940950"},"language":"en","primary_location":{"id":"doi:10.1016/j.carpath.2004.03.277","doi":"https://doi.org/10.1016/j.carpath.2004.03.277","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.carpath.2004.03.277","pdf_url":null,"source":{"id":"https://openalex.org/S176609843","display_name":"Cardiovascular Pathology","issn_l":"1054-8807","issn":["1054-8807","1879-1336"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cardiovascular Pathology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041282316","display_name":"Sudesh Agrawal","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]},{"id":"https://openalex.org/I4405287411","display_name":"Cleveland Clinic Research","ror":"https://ror.org/053229s83","country_code":"US","type":"facility","lineage":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sudesh Agrawal","raw_affiliation_strings":["Department of Cell Biology,The Lerner Research Institute of the Cleveland Clinic Foundation, Cleveland Ohio 44195, USA","Department of Molecular Biology,The Lerner Research Institute of the Cleveland Clinic Foundation, Cleveland Ohio 44195, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology,The Lerner Research Institute of the Cleveland Clinic Foundation, Cleveland Ohio 44195, USA","institution_ids":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]},{"raw_affiliation_string":"Department of Molecular Biology,The Lerner Research Institute of the Cleveland Clinic Foundation, Cleveland Ohio 44195, USA","institution_ids":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043277346","display_name":"Eugene A. Podrez","orcid":"https://orcid.org/0000-0002-9550-6965","observed_orcids":["https://orcid.org/0000-0002-9550-6965","https://orcid.org/0009-0001-6655-3287"]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]},{"id":"https://openalex.org/I4405287411","display_name":"Cleveland Clinic Research","ror":"https://ror.org/053229s83","country_code":"US","type":"facility","lineage":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eugene Podrez","raw_affiliation_strings":["Department of Cell Biology,The Lerner Research Institute of the Cleveland Clinic Foundation, Cleveland Ohio 44195, USA","Department of Molecular Biology,The Lerner Research Institute of the Cleveland Clinic Foundation, Cleveland Ohio 44195, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology,The Lerner Research Institute of the Cleveland Clinic Foundation, Cleveland Ohio 44195, USA","institution_ids":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]},{"raw_affiliation_string":"Department of Molecular Biology,The Lerner Research Institute of the Cleveland Clinic Foundation, Cleveland Ohio 44195, USA","institution_ids":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045228500","display_name":"Bo Xu","orcid":"https://orcid.org/0000-0003-1201-7558","observed_orcids":["https://orcid.org/0000-0003-1201-7558"]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]},{"id":"https://openalex.org/I4405287411","display_name":"Cleveland Clinic Research","ror":"https://ror.org/053229s83","country_code":"US","type":"facility","lineage":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bo Xu","raw_affiliation_strings":["Department of Cell Biology,The Lerner Research Institute of the Cleveland Clinic Foundation, Cleveland Ohio 44195, USA","Department of Molecular Biology,The Lerner Research Institute of the Cleveland Clinic Foundation, Cleveland Ohio 44195, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology,The Lerner Research Institute of the Cleveland Clinic Foundation, Cleveland Ohio 44195, USA","institution_ids":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]},{"raw_affiliation_string":"Department of Molecular Biology,The Lerner Research Institute of the Cleveland Clinic Foundation, Cleveland Ohio 44195, USA","institution_ids":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108469977","display_name":"Martha K. Cathcart","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]},{"id":"https://openalex.org/I4405287411","display_name":"Cleveland Clinic Research","ror":"https://ror.org/053229s83","country_code":"US","type":"facility","lineage":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Martha Cathcart","raw_affiliation_strings":["Department of Cell Biology,The Lerner Research Institute of the Cleveland Clinic Foundation, Cleveland Ohio 44195, USA","Department of Molecular Biology,The Lerner Research Institute of the Cleveland Clinic Foundation, Cleveland Ohio 44195, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology,The Lerner Research Institute of the Cleveland Clinic Foundation, Cleveland Ohio 44195, USA","institution_ids":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]},{"raw_affiliation_string":"Department of Molecular Biology,The Lerner Research Institute of the Cleveland Clinic Foundation, Cleveland Ohio 44195, USA","institution_ids":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080998429","display_name":"George Robert Stark","orcid":"https://orcid.org/0000-0002-8776-9597","observed_orcids":["https://orcid.org/0000-0002-8776-9597"]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]},{"id":"https://openalex.org/I4405287411","display_name":"Cleveland Clinic Research","ror":"https://ror.org/053229s83","country_code":"US","type":"facility","lineage":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"George R Stark","raw_affiliation_strings":["Department of Cell Biology,The Lerner Research Institute of the Cleveland Clinic Foundation, Cleveland Ohio 44195, USA","Department of Molecular Biology,The Lerner Research Institute of the Cleveland Clinic Foundation, Cleveland Ohio 44195, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology,The Lerner Research Institute of the Cleveland Clinic Foundation, Cleveland Ohio 44195, USA","institution_ids":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]},{"raw_affiliation_string":"Department of Molecular Biology,The Lerner Research Institute of the Cleveland Clinic Foundation, Cleveland Ohio 44195, USA","institution_ids":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108789765","display_name":"Guy M. Chisolm","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]},{"id":"https://openalex.org/I4405287411","display_name":"Cleveland Clinic Research","ror":"https://ror.org/053229s83","country_code":"US","type":"facility","lineage":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Guy M Chisolm","raw_affiliation_strings":["Department of Cell Biology,The Lerner Research Institute of the Cleveland Clinic Foundation, Cleveland Ohio 44195, USA","Department of Molecular Biology,The Lerner Research Institute of the Cleveland Clinic Foundation, Cleveland Ohio 44195, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology,The Lerner Research Institute of the Cleveland Clinic Foundation, Cleveland Ohio 44195, USA","institution_ids":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]},{"raw_affiliation_string":"Department of Molecular Biology,The Lerner Research Institute of the Cleveland Clinic Foundation, Cleveland Ohio 44195, USA","institution_ids":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4210,"currency":"USD","value_usd":4210},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.15988027,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"13","issue":"3","first_page":"93","last_page":"94"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":0.7002000212669373,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":0.7002000212669373,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11618","display_name":"Cholesterol and Lipid Metabolism","score":0.2502000033855438,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11503","display_name":"Cytokine Signaling Pathways and Interactions","score":0.027699999511241913,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/stat1","display_name":"STAT1","score":0.8960000276565552},{"id":"https://openalex.org/keywords/foam-cell-formation","display_name":"foam cell formation","score":0.8339999914169312},{"id":"https://openalex.org/keywords/macrophages","display_name":"macrophages","score":0.9990000128746033},{"id":"https://openalex.org/keywords/atherosclerosis","display_name":"atherosclerosis","score":0.8859999775886536},{"id":"https://openalex.org/keywords/signal-transducer-and-activator-of-transcription","display_name":"signal transducer and activator of transcription","score":0.7450000047683716},{"id":"https://openalex.org/keywords/lipid-accumulation","display_name":"lipid accumulation","score":0.3619999885559082}],"concepts":[{"id":"https://openalex.org/C2777895019","wikidata":"https://www.wikidata.org/wiki/Q1425962","display_name":"Foam cell","level":4,"score":0.8603407144546509},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5876593589782715},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5784497857093811},{"id":"https://openalex.org/C2777003663","wikidata":"https://www.wikidata.org/wiki/Q14912030","display_name":"STAT1","level":3,"score":0.4520379304885864},{"id":"https://openalex.org/C2779244956","wikidata":"https://www.wikidata.org/wiki/Q184204","display_name":"Macrophage","level":3,"score":0.3934742510318756},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.16190066933631897},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.15099722146987915},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.13761204481124878},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0888964831829071}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.carpath.2004.03.277","doi":"https://doi.org/10.1016/j.carpath.2004.03.277","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.carpath.2004.03.277","pdf_url":null,"source":{"id":"https://openalex.org/S176609843","display_name":"Cardiovascular Pathology","issn_l":"1054-8807","issn":["1054-8807","1879-1336"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cardiovascular Pathology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4253104268","https://openalex.org/W7096621842","https://openalex.org/W1975576244","https://openalex.org/W1980290794","https://openalex.org/W2401370467","https://openalex.org/W4249453082","https://openalex.org/W3082275425","https://openalex.org/W2055648544","https://openalex.org/W7208215565","https://openalex.org/W2085288170"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-24T09:50:30.924529","created_date":"2016-06-24T00:00:00"}