{"id":"https://openalex.org/W2086724299","doi":"https://doi.org/10.1056/nejmcp052699","title":"Acute Pulmonary Edema","display_name":"Acute Pulmonary Edema","publication_year":2005,"publication_date":"2005-12-28","ids":{"openalex":"https://openalex.org/W2086724299","doi":"https://doi.org/10.1056/nejmcp052699","mag":"2086724299","pmid":"https://pubmed.ncbi.nlm.nih.gov/16382065"},"language":"en","primary_location":{"id":"doi:10.1056/nejmcp052699","doi":"https://doi.org/10.1056/nejmcp052699","is_oa":false,"landing_page_url":"https://doi.org/10.1056/nejmcp052699","pdf_url":null,"source":{"id":"https://openalex.org/S62468778","display_name":"New England Journal of Medicine","issn_l":"0028-4793","issn":["0028-4793","0096-6762","1533-4406","2331-4710"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320239","host_organization_name":"Massachusetts Medical Society","host_organization_lineage":["https://openalex.org/P4310320239"],"host_organization_lineage_names":["Massachusetts Medical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"New England Journal of Medicine","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017253129","display_name":"Lorraine B. Ware","orcid":"https://orcid.org/0000-0002-9429-4702","observed_orcids":["https://orcid.org/0000-0002-9429-4702"]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lorraine B. Ware","raw_affiliation_strings":["Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232-2650, USA","Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232-2650, USA","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I901861585"]},{"raw_affiliation_string":"Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I901861585"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052576862","display_name":"Michael A. Matthay","orcid":"https://orcid.org/0000-0003-3039-8155","observed_orcids":["https://orcid.org/0000-0003-3039-8155"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael A. Matthay","raw_affiliation_strings":["Departments of Medicine and Anesthesia and the Cardiovascular Research Institute, University of California, San Francisco, San Francisco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medicine and Anesthesia and the Cardiovascular Research Institute, University of California, San Francisco, San Francisco","institution_ids":["https://openalex.org/I180670191"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.1395,"has_fulltext":false,"cited_by_count":689,"citation_normalized_percentile":{"value":0.96096441,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"353","issue":"26","first_page":"2788","last_page":"2796"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10198","display_name":"Heart Failure Treatment and Management","score":0.8744999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10198","display_name":"Heart Failure Treatment and Management","score":0.8744999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12082","display_name":"Takotsubo Cardiomyopathy and Associated Phenomena","score":0.045899998396635056,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11738","display_name":"Ultrasound in Clinical Applications","score":0.013500000350177288,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acute-pulmonary-edema","display_name":"acute pulmonary edema","score":1.0},{"id":"https://openalex.org/keywords/dyspnea","display_name":"dyspnea","score":0.9860000014305115},{"id":"https://openalex.org/keywords/hypoxemia","display_name":"hypoxemia","score":0.7300000190734863},{"id":"https://openalex.org/keywords/bilateral-pulmonary-infiltrates","display_name":"bilateral pulmonary infiltrates","score":0.9049999713897705},{"id":"https://openalex.org/keywords/fever","display_name":"fever","score":0.5669999718666077},{"id":"https://openalex.org/keywords/rales","display_name":"rales","score":0.5799999833106995},{"id":"https://openalex.org/keywords/differential-diagnosis","display_name":"differential diagnosis","score":0.550000011920929}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9581034183502197},{"id":"https://openalex.org/C2781137159","wikidata":"https://www.wikidata.org/wiki/Q1283318","display_name":"Chest radiograph","level":3,"score":0.8036870956420898},{"id":"https://openalex.org/C2776468924","wikidata":"https://www.wikidata.org/wiki/Q857667","display_name":"Pulmonary edema","level":3,"score":0.7234161496162415},{"id":"https://openalex.org/C2911060280","wikidata":"https://www.wikidata.org/wiki/Q857667","display_name":"Acute pulmonary edema","level":4,"score":0.6579338908195496},{"id":"https://openalex.org/C2777324038","wikidata":"https://www.wikidata.org/wiki/Q779054","display_name":"Auscultation","level":2,"score":0.5560235977172852},{"id":"https://openalex.org/C2780886150","wikidata":"https://www.wikidata.org/wiki/Q152234","display_name":"Edema","level":2,"score":0.5425165295600891},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.495444655418396},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.46687644720077515},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4036054313182831},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.2602717876434326}],"mesh":[{"descriptor_ui":"D000208","descriptor_name":"Acute Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002407","descriptor_name":"Catheterization, Swan-Ganz","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003937","descriptor_name":"Diagnosis, Differential","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004452","descriptor_name":"Echocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011654","descriptor_name":"Pulmonary Edema","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D011654","descriptor_name":"Pulmonary Edema","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D011859","descriptor_name":"Radiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015633","descriptor_name":"Extravascular Lung Water","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1056/nejmcp052699","doi":"https://doi.org/10.1056/nejmcp052699","is_oa":false,"landing_page_url":"https://doi.org/10.1056/nejmcp052699","pdf_url":null,"source":{"id":"https://openalex.org/S62468778","display_name":"New England Journal of Medicine","issn_l":"0028-4793","issn":["0028-4793","0096-6762","1533-4406","2331-4710"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320239","host_organization_name":"Massachusetts Medical Society","host_organization_lineage":["https://openalex.org/P4310320239"],"host_organization_lineage_names":["Massachusetts Medical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"New England Journal of Medicine","raw_type":"journal-article"},{"id":"pmid:16382065","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16382065","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The New England journal of medicine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9763000011444092}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2720968877","display_name":null,"funder_award_id":"70521","funder_id":"https://openalex.org/F4320332505","funder_display_name":"U.S. Public Health Service"},{"id":"https://openalex.org/G3429402575","display_name":null,"funder_award_id":"HL-51856","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G3554592494","display_name":null,"funder_award_id":"081332","funder_id":"https://openalex.org/F4320332505","funder_display_name":"U.S. Public Health Service"},{"id":"https://openalex.org/G8040598429","display_name":"SCCOR in translational research in Acute Lung Injury","funder_award_id":"P50HL074005","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320332505","display_name":"U.S. Public Health Service","ror":"https://ror.org/05xf94514"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":47,"referenced_works":["https://openalex.org/W1552391318","https://openalex.org/W1925881420","https://openalex.org/W1963681897","https://openalex.org/W1968348773","https://openalex.org/W1970102943","https://openalex.org/W1976427257","https://openalex.org/W1979384626","https://openalex.org/W1981676121","https://openalex.org/W1988816170","https://openalex.org/W1989447605","https://openalex.org/W1996333573","https://openalex.org/W2004588047","https://openalex.org/W2004877120","https://openalex.org/W2009524763","https://openalex.org/W2010006838","https://openalex.org/W2021878071","https://openalex.org/W2025042121","https://openalex.org/W2034619044","https://openalex.org/W2037836255","https://openalex.org/W2044957306","https://openalex.org/W2045772903","https://openalex.org/W2059852730","https://openalex.org/W2067581731","https://openalex.org/W2071449010","https://openalex.org/W2078237412","https://openalex.org/W2081134240","https://openalex.org/W2093852073","https://openalex.org/W2093951586","https://openalex.org/W2095335679","https://openalex.org/W2095916427","https://openalex.org/W2110707896","https://openalex.org/W2117647659","https://openalex.org/W2129788709","https://openalex.org/W2134126443","https://openalex.org/W2147819048","https://openalex.org/W2154390395","https://openalex.org/W2269942624","https://openalex.org/W2299836127","https://openalex.org/W2316621821","https://openalex.org/W2321299297","https://openalex.org/W2322121630","https://openalex.org/W2336550302","https://openalex.org/W2409871786","https://openalex.org/W2550507245","https://openalex.org/W2597070792","https://openalex.org/W4255009698","https://openalex.org/W4294658238"],"related_works":["https://openalex.org/W2241093742","https://openalex.org/W2134707339","https://openalex.org/W4404144730","https://openalex.org/W7135080604","https://openalex.org/W2418241337","https://openalex.org/W2416498927","https://openalex.org/W1423975412","https://openalex.org/W2031449331","https://openalex.org/W50726786","https://openalex.org/W2402329067"],"abstract_inverted_index":{"A":[0,50],"62-year-old":[1],"man":[2],"presents":[3],"with":[4,58],"a":[5],"three-day":[6],"history":[7],"of":[8,64,78],"progressive":[9],"dyspnea,":[10],"nonproductive":[11],"cough,":[12],"and":[13,33,47,61,83],"low-grade":[14],"fever.":[15],"His":[16],"blood":[17],"pressure":[18],"is":[19],"100/60":[20],"mm":[21],"Hg,":[22],"his":[23,30,34],"heart":[24],"rate":[25],"110":[26],"beats":[27],"per":[28],"minute,":[29],"temperature":[31],"37.9\u00b0C,":[32],"oxygen":[35],"saturation":[36],"while":[37],"breathing":[38],"room":[39],"air":[40],"86":[41],"percent.":[42],"Chest":[43],"auscultation":[44],"reveals":[45],"rales":[46],"rhonchi":[48],"bilaterally.":[49],"chest":[51],"radiograph":[52],"shows":[53],"bilateral":[54],"pulmonary":[55,59,81],"infiltrates":[56],"consistent":[57],"edema":[60,82],"borderline":[62],"enlargement":[63],"the":[65,76,79],"cardiac":[66],"silhouette.":[67],"How":[68],"should":[69],"this":[70],"patient":[71],"be":[72],"evaluated":[73],"to":[74,84],"establish":[75],"cause":[77],"acute":[80],"determine":[85],"appropriate":[86],"therapy?":[87]},"counts_by_year":[{"year":2026,"cited_by_count":28},{"year":2025,"cited_by_count":38},{"year":2024,"cited_by_count":17},{"year":2023,"cited_by_count":41},{"year":2022,"cited_by_count":35},{"year":2021,"cited_by_count":33},{"year":2020,"cited_by_count":29},{"year":2019,"cited_by_count":32},{"year":2018,"cited_by_count":30},{"year":2017,"cited_by_count":81},{"year":2016,"cited_by_count":25},{"year":2015,"cited_by_count":22},{"year":2014,"cited_by_count":25},{"year":2013,"cited_by_count":28},{"year":2012,"cited_by_count":46}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}