{"id":"https://openalex.org/W2086655463","doi":"https://doi.org/10.1097/00003246-200004000-00014","title":"Cerebral perfusion, cardiac output, and arterial pressure in patients with fulminant hepatic failure","display_name":"Cerebral perfusion, cardiac output, and arterial pressure in patients with fulminant hepatic failure","publication_year":2000,"publication_date":"2000-04-01","ids":{"openalex":"https://openalex.org/W2086655463","doi":"https://doi.org/10.1097/00003246-200004000-00014","mag":"2086655463","pmid":"https://pubmed.ncbi.nlm.nih.gov/10809272"},"language":"en","primary_location":{"id":"doi:10.1097/00003246-200004000-00014","doi":"https://doi.org/10.1097/00003246-200004000-00014","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00003246-200004000-00014","pdf_url":null,"source":{"id":"https://openalex.org/S108732581","display_name":"Critical Care Medicine","issn_l":"0090-3493","issn":["0090-3493","1530-0293"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical Care Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022504541","display_name":"Fin Stolze Larsen","orcid":"https://orcid.org/0000-0003-2205-8265","observed_orcids":["https://orcid.org/0000-0003-2205-8265"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Fin Stolze Larsen","raw_affiliation_strings":["Department of Hepatology, Rigshospitalet, University of Copenhagen, Denmark. stolze@post3.tele.de","Fin Stolze Larsen, MD, Department of Hepatology A-2121, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen \u00d8, Denmark. E-mail: [email\u00a0protected]","the Departments of Hepatology (Drs. Larsen, Strauss, and Hansen), Neurology (Dr. Knudsen), Cardiology (Dr. Herzog), and Anesthesia (Dr. Secher), Rigshospitalet, University of Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hepatology, Rigshospitalet, University of Copenhagen, Denmark. stolze@post3.tele.de","institution_ids":["https://openalex.org/I124055696","https://openalex.org/I2802709434"]},{"raw_affiliation_string":"Fin Stolze Larsen, MD, Department of Hepatology A-2121, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen \u00d8, Denmark. E-mail: [email\u00a0protected]","institution_ids":["https://openalex.org/I2802709434"]},{"raw_affiliation_string":"the Departments of Hepatology (Drs. Larsen, Strauss, and Hansen), Neurology (Dr. Knudsen), Cardiology (Dr. Herzog), and Anesthesia (Dr. Secher), Rigshospitalet, University of Copenhagen, Denmark","institution_ids":["https://openalex.org/I124055696","https://openalex.org/I2802709434"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113524403","display_name":"Gitte Strauss","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Gitte Strauss","raw_affiliation_strings":["the Departments of Hepatology (Drs. Larsen, Strauss, and Hansen), Neurology (Dr. Knudsen), Cardiology (Dr. Herzog), and Anesthesia (Dr. Secher), Rigshospitalet, University of Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Departments of Hepatology (Drs. Larsen, Strauss, and Hansen), Neurology (Dr. Knudsen), Cardiology (Dr. Herzog), and Anesthesia (Dr. Secher), Rigshospitalet, University of Copenhagen, Denmark","institution_ids":["https://openalex.org/I124055696","https://openalex.org/I2802709434"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015895924","display_name":"Gitte M. Knudsen","orcid":"https://orcid.org/0000-0003-1508-6866","observed_orcids":["https://orcid.org/0000-0003-1508-6866","https://orcid.org/0000-0002-3983-0541"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Gitte Moos Knudsen","raw_affiliation_strings":["the Departments of Hepatology (Drs. Larsen, Strauss, and Hansen), Neurology (Dr. Knudsen), Cardiology (Dr. Herzog), and Anesthesia (Dr. Secher), Rigshospitalet, University of Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Departments of Hepatology (Drs. Larsen, Strauss, and Hansen), Neurology (Dr. Knudsen), Cardiology (Dr. Herzog), and Anesthesia (Dr. Secher), Rigshospitalet, University of Copenhagen, Denmark","institution_ids":["https://openalex.org/I124055696","https://openalex.org/I2802709434"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002338830","display_name":"Tina Maria Herzog","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Tina Maria Herzog","raw_affiliation_strings":["the Departments of Hepatology (Drs. Larsen, Strauss, and Hansen), Neurology (Dr. Knudsen), Cardiology (Dr. Herzog), and Anesthesia (Dr. Secher), Rigshospitalet, University of Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Departments of Hepatology (Drs. Larsen, Strauss, and Hansen), Neurology (Dr. Knudsen), Cardiology (Dr. Herzog), and Anesthesia (Dr. Secher), Rigshospitalet, University of Copenhagen, Denmark","institution_ids":["https://openalex.org/I124055696","https://openalex.org/I2802709434"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103500580","display_name":"Bent Adel Hansen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Bent Adel Hansen","raw_affiliation_strings":["the Departments of Hepatology (Drs. Larsen, Strauss, and Hansen), Neurology (Dr. Knudsen), Cardiology (Dr. Herzog), and Anesthesia (Dr. Secher), Rigshospitalet, University of Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Departments of Hepatology (Drs. Larsen, Strauss, and Hansen), Neurology (Dr. Knudsen), Cardiology (Dr. Herzog), and Anesthesia (Dr. Secher), Rigshospitalet, University of Copenhagen, Denmark","institution_ids":["https://openalex.org/I124055696","https://openalex.org/I2802709434"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050361725","display_name":"Niels Henry Secher","orcid":"https://orcid.org/0000-0002-5207-9932","observed_orcids":["https://orcid.org/0000-0002-5207-9932","https://orcid.org/0000-0001-7972-9731"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Niels H. Secher","raw_affiliation_strings":["the Departments of Hepatology (Drs. Larsen, Strauss, and Hansen), Neurology (Dr. Knudsen), Cardiology (Dr. Herzog), and Anesthesia (Dr. Secher), Rigshospitalet, University of Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Departments of Hepatology (Drs. Larsen, Strauss, and Hansen), Neurology (Dr. Knudsen), Cardiology (Dr. Herzog), and Anesthesia (Dr. Secher), Rigshospitalet, University of Copenhagen, Denmark","institution_ids":["https://openalex.org/I124055696","https://openalex.org/I2802709434"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.3221,"has_fulltext":false,"cited_by_count":52,"citation_normalized_percentile":{"value":0.91763393,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"28","issue":"4","first_page":"996","last_page":"1000"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.9843999743461609,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.9843999743461609,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11700","display_name":"Hemodynamic Monitoring and Therapy","score":0.004000000189989805,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10706","display_name":"Traumatic Brain Injury and Neurovascular Disturbances","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acute-liver-failure","display_name":"acute liver failure","score":0.9980000257492065},{"id":"https://openalex.org/keywords/cerebral-perfusion","display_name":"cerebral perfusion","score":0.9340000152587891},{"id":"https://openalex.org/keywords/cerebral-blood-flow","display_name":"cerebral blood flow","score":0.9700000286102295},{"id":"https://openalex.org/keywords/cardiac-output","display_name":"cardiac output","score":0.9850000143051147},{"id":"https://openalex.org/keywords/cerebral-autoregulation","display_name":"cerebral autoregulation","score":0.8600000143051147},{"id":"https://openalex.org/keywords/norepinephrine-infusion","display_name":"norepinephrine infusion","score":0.8069999814033508},{"id":"https://openalex.org/keywords/arterial-pressure","display_name":"arterial pressure","score":0.7229999899864197},{"id":"https://openalex.org/keywords/hepatic-encephalopathy","display_name":"hepatic encephalopathy","score":0.9079999923706055},{"id":"https://openalex.org/keywords/xenon-clearance","display_name":"xenon clearance","score":0.6200000047683716},{"id":"https://openalex.org/keywords/transcranial-doppler","display_name":"transcranial Doppler","score":0.8939999938011169},{"id":"https://openalex.org/keywords/mean-flow-velocity","display_name":"mean flow velocity","score":0.6639999747276306},{"id":"https://openalex.org/keywords/mechanical-ventilation","display_name":"mechanical ventilation","score":0.6660000085830688},{"id":"https://openalex.org/keywords/vasopressor-support","display_name":"vasopressor therapy","score":0.6029999852180481},{"id":"https://openalex.org/keywords/cerebral-vasoconstriction","display_name":"cerebral vasoconstriction","score":0.5130000114440918},{"id":"https://openalex.org/keywords/cerebral-vasodilation","display_name":"cerebral vasodilation","score":0.503000020980835}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8659729957580566},{"id":"https://openalex.org/C139940330","wikidata":"https://www.wikidata.org/wiki/Q596579","display_name":"Cardiac output","level":3,"score":0.706150472164154},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.546697735786438},{"id":"https://openalex.org/C2911118192","wikidata":"https://www.wikidata.org/wiki/Q1192530","display_name":"Fulminant hepatic failure","level":4,"score":0.5312010645866394},{"id":"https://openalex.org/C157767197","wikidata":"https://www.wikidata.org/wiki/Q886843","display_name":"Cerebral blood flow","level":2,"score":0.5011823177337646},{"id":"https://openalex.org/C84359808","wikidata":"https://www.wikidata.org/wiki/Q13365173","display_name":"Cerebral autoregulation","level":4,"score":0.49874377250671387},{"id":"https://openalex.org/C154281038","wikidata":"https://www.wikidata.org/wiki/Q629232","display_name":"Cerebral perfusion pressure","level":3,"score":0.49746015667915344},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4948059916496277},{"id":"https://openalex.org/C2776452961","wikidata":"https://www.wikidata.org/wiki/Q1940733","display_name":"Mean arterial pressure","level":4,"score":0.4782603979110718},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.45432227849960327},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.4254772663116455},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.3473154902458191},{"id":"https://openalex.org/C111774379","wikidata":"https://www.wikidata.org/wiki/Q1364253","display_name":"Autoregulation","level":3,"score":0.18684998154640198},{"id":"https://openalex.org/C2779609443","wikidata":"https://www.wikidata.org/wiki/Q1368191","display_name":"Liver transplantation","level":3,"score":0.1553700864315033},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.1403471827507019},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.1294034719467163}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001783","descriptor_name":"Blood Flow Velocity","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001783","descriptor_name":"Blood Flow Velocity","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002302","descriptor_name":"Cardiac Output","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002302","descriptor_name":"Cardiac Output","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002560","descriptor_name":"Cerebrovascular Circulation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002560","descriptor_name":"Cerebrovascular Circulation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009638","descriptor_name":"Norepinephrine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011877","descriptor_name":"Radionuclide Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014662","descriptor_name":"Vasoconstrictor Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D014980","descriptor_name":"Xenon Radioisotopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017093","descriptor_name":"Liver Failure","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D017093","descriptor_name":"Liver Failure","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D017585","descriptor_name":"Ultrasonography, Doppler, Transcranial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1097/00003246-200004000-00014","doi":"https://doi.org/10.1097/00003246-200004000-00014","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00003246-200004000-00014","pdf_url":null,"source":{"id":"https://openalex.org/S108732581","display_name":"Critical Care Medicine","issn_l":"0090-3493","issn":["0090-3493","1530-0293"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical Care Medicine","raw_type":"journal-article"},{"id":"pmid:10809272","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10809272","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical care medicine","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W57275787","https://openalex.org/W1968415998","https://openalex.org/W1971234316","https://openalex.org/W1975061975","https://openalex.org/W1981061222","https://openalex.org/W1981745134","https://openalex.org/W2000857827","https://openalex.org/W2001509175","https://openalex.org/W2002664751","https://openalex.org/W2011499825","https://openalex.org/W2023629631","https://openalex.org/W2039208700","https://openalex.org/W2044293948","https://openalex.org/W2051819654","https://openalex.org/W2054754621","https://openalex.org/W2057086331","https://openalex.org/W2057305034","https://openalex.org/W2067735566","https://openalex.org/W2083982626","https://openalex.org/W2086957693","https://openalex.org/W2105269204","https://openalex.org/W2117712067","https://openalex.org/W2160749102","https://openalex.org/W2201476461","https://openalex.org/W2406460337"],"related_works":["https://openalex.org/W2011499825","https://openalex.org/W2056402170","https://openalex.org/W2057086331","https://openalex.org/W2418673163","https://openalex.org/W2091650265","https://openalex.org/W2139131748","https://openalex.org/W2005939708","https://openalex.org/W2069548039","https://openalex.org/W2000716155","https://openalex.org/W1605655846"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"evaluate":[2],"whether":[3],"changes":[4],"in":[5,23,151,192,297,302,307,342,361,369],"cardiac":[6,24,39,50,113,155,167,185,200,225,238,246,285,322,340],"output":[7,25,40,114,156,201,286,323,341],"influence":[8],"cerebral":[9,27,48,176,352,366,374,377],"perfusion":[10,123],"directly.":[11],"In":[12,169,221],"fulminant":[13,73,345],"hepatic":[14,74,101,346],"failure,":[15],"the":[16,127,170,174,355,371],"circulation":[17,353],"is":[18],"characterized":[19],"by":[20,116,126,135,180],"wide":[21],"variations":[22],"and":[26,38,43,52,112,118,134,149,187,214,229,300,364,368,376],"blood":[28],"flow":[29,145],"(CBF).":[30],"DESIGN:":[31],"A":[32,61],"retrospective,":[33],"interindividual":[34],"analysis":[35],"of":[36,47,100,173,183,350,357,373],"CBF":[37,148,207,230,241,332],"(part":[41,58],"1)":[42],"a":[44],"prospective":[45],"evaluation":[46],"perfusion,":[49],"output,":[51,186,226],"arterial":[53,109,335],"pressure":[54,110,336],"during":[55,189],"norepinephrine":[56,190,249],"infusion":[57,191],"2).":[59],"SETTING:":[60],"four-bed":[62],"specialist":[63],"liver":[64],"failure":[65,75],"unit.":[66],"PATIENTS":[67],"AND":[68,196],"INTERVENTIONS:":[69],"Twenty":[70],"patients":[71,152,222,235,299,343],"with":[72,153,161,163,223,234,236,344],"(median":[76],"age,":[77],"43":[78],"yrs;":[79],"range,":[80,93],"17-54;":[81],"13":[82],"women)":[83],"maintained":[84],"on":[85],"mechanical":[86],"ventilation":[87],"(Paco2,":[88],"33":[89,209],"torr":[90,95],"[4.40":[91],"kPa];":[92],"26-36":[94],"[3.47-4.80":[96],"kPa)":[97],"after":[98],"development":[99,372],"encephalopathy,":[102],"stages":[103],"3":[104],"to":[105,142,245,258,276,311,321,334,339],"4,":[106],"had":[107],"mean":[108,144],"(MAP)":[111],"determined":[115],"radial":[117],"pulmonary":[119],"artery":[120],"catheters.":[121],"Cerebral":[122],"was":[124,140,178,202,208,216,309],"measured":[125],"133Xenon":[128],"clearance":[129],"technique":[130],"(n":[131],"=":[132,314,325],"8)":[133],"transcranial":[136],"Doppler":[137],"sonography,":[138],"which":[139],"used":[141],"measure":[143],"velocity":[146],"(Vmean).":[147],"Vmean":[150,215,243,251,308],"high":[154],"(>9":[157],"L/min)":[158],"were":[159,231],"compared":[160,233],"those":[162],"normal":[164,237],"or":[165],"low":[166],"output.":[168,239,247],"second":[171],"part":[172],"study,":[175],"autoregulation":[177],"evaluated":[179],"concomitant":[181],"measurement":[182],"Vmean,":[184,228],"MAP":[188,267,312],"nine":[193],"patients.":[194,304],"MEASUREMENTS":[195],"MAIN":[197],"RESULTS:":[198],"Median":[199],"8.5":[203],"L/min":[204,291],"(range,":[205,292],"3.2-17.3),":[206,293],"mL/100":[210],"g/min":[211],"(12-77":[212],"g/min),":[213],"45":[217],"cm/sec":[218,255,260],"(22-65":[219],"cm/sec).":[220],"elevated":[224],"MAP,":[227],"similar":[232],"Neither":[240],"nor":[242],"correlated":[244],"During":[248],"infusion,":[250],"increased":[252,268,296],"from":[253,269],"49":[254],"(34-69":[256],"cm/sec)":[257],"63":[259],"(58-90":[261],"cm/sec;":[262],"p":[263,316],"<":[264,317],".05),":[265],"as":[266,294],"75":[270],"mm":[271,274,278,281],"Hg":[272,279],"(54-105":[273],"Hg)":[275],"97":[277],"(90-128":[280],"Hg).":[282],"On":[283],"average,":[284],"remained":[287],"unchanged":[288],"at":[289],"5.7":[290],"it":[295],"five":[298],"decreased":[301],"four":[303],"The":[305,348],"change":[306],"related":[310],"(r2":[313,324],".76;":[315],".01)":[318],"but":[319],"not":[320],".01).":[326],"CONCLUSION:":[327],"This":[328],"study":[329],"shows":[330],"that":[331],"correlates":[333],"rather":[337],"than":[338],"failure.":[347],"presence":[349],"pressure-passive":[351],"stresses":[354],"importance":[356],"strict":[358],"cardiovascular":[359],"control":[360],"securing":[362],"continuous":[363],"sufficient":[365],"oxygenation":[367],"avoiding":[370],"hyperemia":[375],"edema.":[378]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":4},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
