{"id":"https://openalex.org/W2086494545","doi":"https://doi.org/10.1016/j.conb.2011.09.008","title":"Posttranslational regulation of AMPA receptor trafficking and function","display_name":"Posttranslational regulation of AMPA receptor trafficking and function","publication_year":2011,"publication_date":"2011-10-17","ids":{"openalex":"https://openalex.org/W2086494545","doi":"https://doi.org/10.1016/j.conb.2011.09.008","mag":"2086494545","pmid":"https://pubmed.ncbi.nlm.nih.gov/22000952","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3279598"},"language":"en","primary_location":{"id":"doi:10.1016/j.conb.2011.09.008","doi":"https://doi.org/10.1016/j.conb.2011.09.008","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.conb.2011.09.008","pdf_url":null,"source":{"id":"https://openalex.org/S120775027","display_name":"Current Opinion in Neurobiology","issn_l":"0959-4388","issn":["0959-4388","1873-6882"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Neurobiology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3279598","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100673138","display_name":"Wei L\u00fc","orcid":"https://orcid.org/0000-0001-6668-8432","observed_orcids":["https://orcid.org/0000-0001-6668-8432"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]},{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Wei Lu","raw_affiliation_strings":["Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94143, USA. luwei@cmp.ucsf.edu","Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94143, USA","National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94143, USA. luwei@cmp.ucsf.edu","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94143, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210110767"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071397864","display_name":"Katherine W. Roche","orcid":"https://orcid.org/0000-0001-7282-6539","observed_orcids":["https://orcid.org/0000-0001-7282-6539"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Katherine W Roche","raw_affiliation_strings":["National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210110767"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5071397864","https://openalex.org/A5100673138"],"corresponding_institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I180670191","https://openalex.org/I4210110767"],"apc_list":{"value":4320,"currency":"USD","value_usd":4320},"apc_paid":null,"fwci":1.6382,"has_fulltext":false,"cited_by_count":197,"citation_normalized_percentile":{"value":0.85207101,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"22","issue":"3","first_page":"470","last_page":"479"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12770","display_name":"Amino Acid Enzymes and Metabolism","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ampa-receptors","display_name":"AMPA receptors","score":0.8769999742507935},{"id":"https://openalex.org/keywords/post-translational-modification","display_name":"post-translational modification","score":0.878000020980835},{"id":"https://openalex.org/keywords/receptor-trafficking","display_name":"receptor trafficking","score":0.9649999737739563},{"id":"https://openalex.org/keywords/synaptic-plasticity","display_name":"synaptic plasticity","score":0.6539999842643738},{"id":"https://openalex.org/keywords/glutamate-receptors","display_name":"glutamate receptors","score":0.5849999785423279},{"id":"https://openalex.org/keywords/phosphorylation","display_name":"phosphorylation","score":0.7350000143051147},{"id":"https://openalex.org/keywords/protein-palmitoylation","display_name":"palmitoylation","score":0.9990000128746033},{"id":"https://openalex.org/keywords/ubiquitination","display_name":"ubiquitination","score":1.0},{"id":"https://openalex.org/keywords/excitatory-synaptic-transmission","display_name":"excitatory synaptic transmission","score":0.7749999761581421},{"id":"https://openalex.org/keywords/learning-and-memory","display_name":"learning and memory","score":0.9079999923706055}],"concepts":[{"id":"https://openalex.org/C160268369","wikidata":"https://www.wikidata.org/wiki/Q295251","display_name":"AMPA receptor","level":4,"score":0.955485999584198},{"id":"https://openalex.org/C154559735","wikidata":"https://www.wikidata.org/wiki/Q7514768","display_name":"Silent synapse","level":5,"score":0.7071665525436401},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.636942982673645},{"id":"https://openalex.org/C73009533","wikidata":"https://www.wikidata.org/wiki/Q1517140","display_name":"Long-term depression","level":5,"score":0.6207332015037537},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.48644304275512695},{"id":"https://openalex.org/C200170125","wikidata":"https://www.wikidata.org/wiki/Q969316","display_name":"Neurotransmission","level":3,"score":0.47268015146255493},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.45801275968551636},{"id":"https://openalex.org/C88272193","wikidata":"https://www.wikidata.org/wiki/Q418536","display_name":"Ion channel linked receptors","level":5,"score":0.45477694272994995},{"id":"https://openalex.org/C184150571","wikidata":"https://www.wikidata.org/wiki/Q18031469","display_name":"SGK1","level":3,"score":0.45288988947868347},{"id":"https://openalex.org/C61174792","wikidata":"https://www.wikidata.org/wiki/Q420510","display_name":"Glutamate receptor","level":3,"score":0.4431019425392151},{"id":"https://openalex.org/C115955781","wikidata":"https://www.wikidata.org/wiki/Q6063798","display_name":"Ionotropic effect","level":4,"score":0.41084539890289307},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.3503573536872864},{"id":"https://openalex.org/C11960822","wikidata":"https://www.wikidata.org/wiki/Q242736","display_name":"Phosphorylation","level":2,"score":0.2751502990722656},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.11598154902458191}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013569","descriptor_name":"Synapses","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014176","descriptor_name":"Protein Biosynthesis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D018091","descriptor_name":"Receptors, AMPA","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D021381","descriptor_name":"Protein Transport","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.conb.2011.09.008","doi":"https://doi.org/10.1016/j.conb.2011.09.008","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.conb.2011.09.008","pdf_url":null,"source":{"id":"https://openalex.org/S120775027","display_name":"Current Opinion in Neurobiology","issn_l":"0959-4388","issn":["0959-4388","1873-6882"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Neurobiology","raw_type":"journal-article"},{"id":"pmid:22000952","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22000952","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current opinion in neurobiology","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:2662738","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3279598","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3279598","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3279598","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Curr Opin Neurobiol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2662738","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3279598","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G5780505447","display_name":null,"funder_award_id":"K99 MH090239","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G6378272331","display_name":null,"funder_award_id":"K99 MH090239-01A1","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G7760575770","display_name":"Role of the Loop1 Domain in AMPA Receptor Trafficking","funder_award_id":"1k99mh090239-01a1","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000858409","display_name":"Subunit-Specific Regulation Of Glutamate Receptors","funder_award_id":"ZIANS002994","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":93,"referenced_works":["https://openalex.org/W89773539","https://openalex.org/W1494623690","https://openalex.org/W1595234035","https://openalex.org/W1604295762","https://openalex.org/W1609834322","https://openalex.org/W1641016126","https://openalex.org/W1756593109","https://openalex.org/W1870408217","https://openalex.org/W1929828037","https://openalex.org/W1965400901","https://openalex.org/W1966017317","https://openalex.org/W1967271803","https://openalex.org/W1978155331","https://openalex.org/W1979586675","https://openalex.org/W1982195853","https://openalex.org/W1983105204","https://openalex.org/W1983252720","https://openalex.org/W1991211989","https://openalex.org/W1991789257","https://openalex.org/W1994805914","https://openalex.org/W1995680954","https://openalex.org/W1996669272","https://openalex.org/W1997276312","https://openalex.org/W2001516087","https://openalex.org/W2001679254","https://openalex.org/W2003247806","https://openalex.org/W2004250476","https://openalex.org/W2006259718","https://openalex.org/W2010939168","https://openalex.org/W2012995243","https://openalex.org/W2018458016","https://openalex.org/W2019035666","https://openalex.org/W2024207015","https://openalex.org/W2027046812","https://openalex.org/W2027436298","https://openalex.org/W2029359382","https://openalex.org/W2030126027","https://openalex.org/W2034502353","https://openalex.org/W2036668494","https://openalex.org/W2036834190","https://openalex.org/W2037852973","https://openalex.org/W2037873496","https://openalex.org/W2038133979","https://openalex.org/W2045117528","https://openalex.org/W2045780885","https://openalex.org/W2046496537","https://openalex.org/W2047535883","https://openalex.org/W2048247819","https://openalex.org/W2048932608","https://openalex.org/W2051323125","https://openalex.org/W2052000300","https://openalex.org/W2052322593","https://openalex.org/W2052415426","https://openalex.org/W2052495973","https://openalex.org/W2053055918","https://openalex.org/W2053651900","https://openalex.org/W2055234453","https://openalex.org/W2066507838","https://openalex.org/W2067876231","https://openalex.org/W2074385487","https://openalex.org/W2075621633","https://openalex.org/W2076304606","https://openalex.org/W2079398298","https://openalex.org/W2087167617","https://openalex.org/W2100139095","https://openalex.org/W2102170165","https://openalex.org/W2106828113","https://openalex.org/W2107339318","https://openalex.org/W2109208582","https://openalex.org/W2109476749","https://openalex.org/W2110405052","https://openalex.org/W2124638528","https://openalex.org/W2128574573","https://openalex.org/W2128834282","https://openalex.org/W2129108032","https://openalex.org/W2133623572","https://openalex.org/W2133987610","https://openalex.org/W2134225499","https://openalex.org/W2138136052","https://openalex.org/W2141680511","https://openalex.org/W2151538478","https://openalex.org/W2161036636","https://openalex.org/W2162552344","https://openalex.org/W2162642602","https://openalex.org/W2165278449","https://openalex.org/W2166978025","https://openalex.org/W2167320436","https://openalex.org/W2168319429","https://openalex.org/W2168971983","https://openalex.org/W2169578249","https://openalex.org/W2170532212","https://openalex.org/W2291961905","https://openalex.org/W2410857538"],"related_works":["https://openalex.org/W7165151910","https://openalex.org/W2176816948","https://openalex.org/W2012995243","https://openalex.org/W4256018609","https://openalex.org/W4315620586","https://openalex.org/W1976598676","https://openalex.org/W2081551641","https://openalex.org/W2138136052","https://openalex.org/W2053651900","https://openalex.org/W137194047"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":12},{"year":2022,"cited_by_count":13},{"year":2021,"cited_by_count":15},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":11},{"year":2018,"cited_by_count":14},{"year":2017,"cited_by_count":14},{"year":2016,"cited_by_count":16},{"year":2015,"cited_by_count":24},{"year":2014,"cited_by_count":19},{"year":2013,"cited_by_count":21},{"year":2012,"cited_by_count":12}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}