{"id":"https://openalex.org/W2086452003","doi":"https://doi.org/10.1093/nar/4.7.2321","title":"Nucleoside 3'-phosphotriesters as key intermediates for the oligoribonucleotide synthesis. IV. New method for removal of 2,2,2-trichioroethyl group and31NMR as a new tool for analysis of deblocking of intemucleotide phosphate protecting groups","display_name":"Nucleoside 3'-phosphotriesters as key intermediates for the oligoribonucleotide synthesis. IV. New method for removal of 2,2,2-trichioroethyl group and31NMR as a new tool for analysis of deblocking of intemucleotide phosphate protecting groups","publication_year":1977,"publication_date":"1977-01-01","ids":{"openalex":"https://openalex.org/W2086452003","doi":"https://doi.org/10.1093/nar/4.7.2321","mag":"2086452003","pmid":"https://pubmed.ncbi.nlm.nih.gov/909778","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/342569"},"language":"en","primary_location":{"id":"doi:10.1093/nar/4.7.2321","doi":"https://doi.org/10.1093/nar/4.7.2321","is_oa":false,"landing_page_url":"https://doi.org/10.1093/nar/4.7.2321","pdf_url":null,"source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC342569","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5066355029","display_name":"Ryszard W. Adamiak","orcid":"https://orcid.org/0000-0001-8914-9618","observed_orcids":["https://orcid.org/0000-0001-8914-9618"]},"institutions":[{"id":"https://openalex.org/I4210109745","display_name":"Institute of Organic Chemistry","ror":"https://ror.org/01e17d143","country_code":"PL","type":"facility","lineage":["https://openalex.org/I4210109745","https://openalex.org/I99542240"]},{"id":"https://openalex.org/I99542240","display_name":"Polish Academy of Sciences","ror":"https://ror.org/01dr6c206","country_code":"PL","type":"government","lineage":["https://openalex.org/I99542240"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"R. W. Adamiak","raw_affiliation_strings":["Department of Stereochemistry of Natural Products, Institute of Organic Chemistry. Polish Academy of Sciences, Noskowskiego 12/14, 61-704 pozn\u00e1n, Poland","Department of Stereochemistry of Natural Products, Institute of Organic Chemistry, Polish Academy of Sciences Noskowskiego 12/14, 61-704 Pozna\u0144, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Stereochemistry of Natural Products, Institute of Organic Chemistry. Polish Academy of Sciences, Noskowskiego 12/14, 61-704 pozn\u00e1n, Poland","institution_ids":["https://openalex.org/I4210109745","https://openalex.org/I99542240"]},{"raw_affiliation_string":"Department of Stereochemistry of Natural Products, Institute of Organic Chemistry, Polish Academy of Sciences Noskowskiego 12/14, 61-704 Pozna\u0144, Poland","institution_ids":["https://openalex.org/I4210109745","https://openalex.org/I99542240"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045574743","display_name":"Ewa Bia\u0142a","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210109745","display_name":"Institute of Organic Chemistry","ror":"https://ror.org/01e17d143","country_code":"PL","type":"facility","lineage":["https://openalex.org/I4210109745","https://openalex.org/I99542240"]},{"id":"https://openalex.org/I99542240","display_name":"Polish Academy of Sciences","ror":"https://ror.org/01dr6c206","country_code":"PL","type":"government","lineage":["https://openalex.org/I99542240"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"E. Bia\u0142a","raw_affiliation_strings":["Department of Stereochemistry of Natural Products, Institute of Organic Chemistry. Polish Academy of Sciences, Noskowskiego 12/14, 61-704 pozn\u00e1n, Poland","Department of Stereochemistry of Natural Products, Institute of Organic Chemistry, Polish Academy of Sciences Noskowskiego 12/14, 61-704 Pozna\u0144, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Stereochemistry of Natural Products, Institute of Organic Chemistry. Polish Academy of Sciences, Noskowskiego 12/14, 61-704 pozn\u00e1n, Poland","institution_ids":["https://openalex.org/I4210109745","https://openalex.org/I99542240"]},{"raw_affiliation_string":"Department of Stereochemistry of Natural Products, Institute of Organic Chemistry, Polish Academy of Sciences Noskowskiego 12/14, 61-704 Pozna\u0144, Poland","institution_ids":["https://openalex.org/I4210109745","https://openalex.org/I99542240"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111601519","display_name":"K. Grze\u015bkowiak","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210109745","display_name":"Institute of Organic Chemistry","ror":"https://ror.org/01e17d143","country_code":"PL","type":"facility","lineage":["https://openalex.org/I4210109745","https://openalex.org/I99542240"]},{"id":"https://openalex.org/I99542240","display_name":"Polish Academy of Sciences","ror":"https://ror.org/01dr6c206","country_code":"PL","type":"government","lineage":["https://openalex.org/I99542240"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"K. Grz\u00e9skowiak","raw_affiliation_strings":["Department of Stereochemistry of Natural Products, Institute of Organic Chemistry. Polish Academy of Sciences, Noskowskiego 12/14, 61-704 pozn\u00e1n, Poland","Department of Stereochemistry of Natural Products, Institute of Organic Chemistry, Polish Academy of Sciences Noskowskiego 12/14, 61-704 Pozna\u0144, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Stereochemistry of Natural Products, Institute of Organic Chemistry. Polish Academy of Sciences, Noskowskiego 12/14, 61-704 pozn\u00e1n, Poland","institution_ids":["https://openalex.org/I4210109745","https://openalex.org/I99542240"]},{"raw_affiliation_string":"Department of Stereochemistry of Natural Products, Institute of Organic Chemistry, Polish Academy of Sciences Noskowskiego 12/14, 61-704 Pozna\u0144, Poland","institution_ids":["https://openalex.org/I4210109745","https://openalex.org/I99542240"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078966154","display_name":"Ryszard Kierzek","orcid":"https://orcid.org/0000-0002-7644-0016","observed_orcids":["https://orcid.org/0000-0002-7644-0016"]},"institutions":[{"id":"https://openalex.org/I4210109745","display_name":"Institute of Organic Chemistry","ror":"https://ror.org/01e17d143","country_code":"PL","type":"facility","lineage":["https://openalex.org/I4210109745","https://openalex.org/I99542240"]},{"id":"https://openalex.org/I99542240","display_name":"Polish Academy of Sciences","ror":"https://ror.org/01dr6c206","country_code":"PL","type":"government","lineage":["https://openalex.org/I99542240"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"R. Kierzek","raw_affiliation_strings":["Department of Stereochemistry of Natural Products, Institute of Organic Chemistry. Polish Academy of Sciences, Noskowskiego 12/14, 61-704 pozn\u00e1n, Poland","Department of Stereochemistry of Natural Products, Institute of Organic Chemistry, Polish Academy of Sciences Noskowskiego 12/14, 61-704 Pozna\u0144, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Stereochemistry of Natural Products, Institute of Organic Chemistry. Polish Academy of Sciences, Noskowskiego 12/14, 61-704 pozn\u00e1n, Poland","institution_ids":["https://openalex.org/I4210109745","https://openalex.org/I99542240"]},{"raw_affiliation_string":"Department of Stereochemistry of Natural Products, Institute of Organic Chemistry, Polish Academy of Sciences Noskowskiego 12/14, 61-704 Pozna\u0144, Poland","institution_ids":["https://openalex.org/I4210109745","https://openalex.org/I99542240"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035693922","display_name":"Adam Kraszewski","orcid":"https://orcid.org/0000-0001-9651-1726","observed_orcids":["https://orcid.org/0000-0001-9651-1726"]},"institutions":[{"id":"https://openalex.org/I4210109745","display_name":"Institute of Organic Chemistry","ror":"https://ror.org/01e17d143","country_code":"PL","type":"facility","lineage":["https://openalex.org/I4210109745","https://openalex.org/I99542240"]},{"id":"https://openalex.org/I99542240","display_name":"Polish Academy of Sciences","ror":"https://ror.org/01dr6c206","country_code":"PL","type":"government","lineage":["https://openalex.org/I99542240"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"A. Kraszewski","raw_affiliation_strings":["Department of Stereochemistry of Natural Products, Institute of Organic Chemistry. Polish Academy of Sciences, Noskowskiego 12/14, 61-704 pozn\u00e1n, Poland","Department of Stereochemistry of Natural Products, Institute of Organic Chemistry, Polish Academy of Sciences Noskowskiego 12/14, 61-704 Pozna\u0144, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Stereochemistry of Natural Products, Institute of Organic Chemistry. Polish Academy of Sciences, Noskowskiego 12/14, 61-704 pozn\u00e1n, Poland","institution_ids":["https://openalex.org/I4210109745","https://openalex.org/I99542240"]},{"raw_affiliation_string":"Department of Stereochemistry of Natural Products, Institute of Organic Chemistry, Polish Academy of Sciences Noskowskiego 12/14, 61-704 Pozna\u0144, Poland","institution_ids":["https://openalex.org/I4210109745","https://openalex.org/I99542240"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019827988","display_name":"Wojciech T. Markiewicz","orcid":"https://orcid.org/0000-0002-7337-6610","observed_orcids":["https://orcid.org/0000-0002-7337-6610"]},"institutions":[{"id":"https://openalex.org/I4210109745","display_name":"Institute of Organic Chemistry","ror":"https://ror.org/01e17d143","country_code":"PL","type":"facility","lineage":["https://openalex.org/I4210109745","https://openalex.org/I99542240"]},{"id":"https://openalex.org/I99542240","display_name":"Polish Academy of Sciences","ror":"https://ror.org/01dr6c206","country_code":"PL","type":"government","lineage":["https://openalex.org/I99542240"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"W.T. Markiewicz","raw_affiliation_strings":["Department of Stereochemistry of Natural Products, Institute of Organic Chemistry. Polish Academy of Sciences, Noskowskiego 12/14, 61-704 pozn\u00e1n, Poland","Department of Stereochemistry of Natural Products, Institute of Organic Chemistry, Polish Academy of Sciences Noskowskiego 12/14, 61-704 Pozna\u0144, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Stereochemistry of Natural Products, Institute of Organic Chemistry. Polish Academy of Sciences, Noskowskiego 12/14, 61-704 pozn\u00e1n, Poland","institution_ids":["https://openalex.org/I4210109745","https://openalex.org/I99542240"]},{"raw_affiliation_string":"Department of Stereochemistry of Natural Products, Institute of Organic Chemistry, Polish Academy of Sciences Noskowskiego 12/14, 61-704 Pozna\u0144, Poland","institution_ids":["https://openalex.org/I4210109745","https://openalex.org/I99542240"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085989985","display_name":"Jacek Stawi\u0144ski","orcid":"https://orcid.org/0000-0001-9350-3018","observed_orcids":["https://orcid.org/0000-0001-9350-3018"]},"institutions":[{"id":"https://openalex.org/I4210109745","display_name":"Institute of Organic Chemistry","ror":"https://ror.org/01e17d143","country_code":"PL","type":"facility","lineage":["https://openalex.org/I4210109745","https://openalex.org/I99542240"]},{"id":"https://openalex.org/I99542240","display_name":"Polish Academy of Sciences","ror":"https://ror.org/01dr6c206","country_code":"PL","type":"government","lineage":["https://openalex.org/I99542240"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"J. Staw\u00ednski","raw_affiliation_strings":["Department of Stereochemistry of Natural Products, Institute of Organic Chemistry. Polish Academy of Sciences, Noskowskiego 12/14, 61-704 pozn\u00e1n, Poland","Department of Stereochemistry of Natural Products, Institute of Organic Chemistry, Polish Academy of Sciences Noskowskiego 12/14, 61-704 Pozna\u0144, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Stereochemistry of Natural Products, Institute of Organic Chemistry. Polish Academy of Sciences, Noskowskiego 12/14, 61-704 pozn\u00e1n, Poland","institution_ids":["https://openalex.org/I4210109745","https://openalex.org/I99542240"]},{"raw_affiliation_string":"Department of Stereochemistry of Natural Products, Institute of Organic Chemistry, Polish Academy of Sciences Noskowskiego 12/14, 61-704 Pozna\u0144, Poland","institution_ids":["https://openalex.org/I4210109745","https://openalex.org/I99542240"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031134021","display_name":"M. Wiewi\u00f3rowski","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210109745","display_name":"Institute of Organic Chemistry","ror":"https://ror.org/01e17d143","country_code":"PL","type":"facility","lineage":["https://openalex.org/I4210109745","https://openalex.org/I99542240"]},{"id":"https://openalex.org/I99542240","display_name":"Polish Academy of Sciences","ror":"https://ror.org/01dr6c206","country_code":"PL","type":"government","lineage":["https://openalex.org/I99542240"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"M. Wiewi\u00f3rowski","raw_affiliation_strings":["Department of Stereochemistry of Natural Products, Institute of Organic Chemistry, Polish Academy of Sciences Noskowskiego 12/14, 61-704 Pozna\u0144, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Stereochemistry of Natural Products, Institute of Organic Chemistry, Polish Academy of Sciences Noskowskiego 12/14, 61-704 Pozna\u0144, Poland","institution_ids":["https://openalex.org/I4210109745","https://openalex.org/I99542240"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3992,"currency":"USD","value_usd":3992},"apc_paid":null,"fwci":2.0339,"has_fulltext":false,"cited_by_count":52,"citation_normalized_percentile":{"value":0.86486103,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"4","issue":"7","first_page":"2321","last_page":"2330"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.9682999849319458,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.9682999849319458,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11748","display_name":"Organophosphorus compounds synthesis","score":0.019999999552965164,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13239","display_name":"Phosphorus compounds and reactions","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oligoribonucleotide-synthesis","display_name":"oligoribonucleotide synthesis","score":0.9700000286102295},{"id":"https://openalex.org/keywords/phosphodiester","display_name":"phosphodiester","score":0.753000020980835},{"id":"https://openalex.org/keywords/31p-nmr-spectroscopy","display_name":"31P NMR","score":0.7490000128746033},{"id":"https://openalex.org/keywords/phosphotriester-approach","display_name":"phosphotriester approach","score":0.6589999794960022}],"concepts":[{"id":"https://openalex.org/C2776543447","wikidata":"https://www.wikidata.org/wiki/Q28734","display_name":"Nucleoside","level":2,"score":0.6561903953552246},{"id":"https://openalex.org/C66974803","wikidata":"https://www.wikidata.org/wiki/Q10359898","display_name":"Nuclear magnetic resonance spectroscopy","level":2,"score":0.539452850818634},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5182301998138428},{"id":"https://openalex.org/C129312508","wikidata":"https://www.wikidata.org/wiki/Q133686","display_name":"Oligonucleotide","level":3,"score":0.5112428665161133},{"id":"https://openalex.org/C134121241","wikidata":"https://www.wikidata.org/wiki/Q899301","display_name":"Yield (engineering)","level":2,"score":0.5065640211105347},{"id":"https://openalex.org/C2779485729","wikidata":"https://www.wikidata.org/wiki/Q210385","display_name":"Pyridine","level":2,"score":0.48542293906211853},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.47832798957824707},{"id":"https://openalex.org/C2779598120","wikidata":"https://www.wikidata.org/wiki/Q5462356","display_name":"Floxuridine","level":4,"score":0.4397527575492859},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.3356844484806061},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2642408013343811},{"id":"https://openalex.org/C155647269","wikidata":"https://www.wikidata.org/wiki/Q243455","display_name":"Medicinal chemistry","level":1,"score":0.1845940351486206},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.18186181783676147},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.1119680404663086},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.058960139751434326},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.0},{"id":"https://openalex.org/C2780456651","wikidata":"https://www.wikidata.org/wiki/Q238512","display_name":"Fluorouracil","level":3,"score":0.0},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D002855","descriptor_name":"Chromatography, Thin Layer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008722","descriptor_name":"Methods","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009841","descriptor_name":"Oligonucleotides","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":true},{"descriptor_ui":"D009843","descriptor_name":"Oligoribonucleotides","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":true},{"descriptor_ui":"D009943","descriptor_name":"Organophosphorus Compounds","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012265","descriptor_name":"Ribonucleotides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015032","descriptor_name":"Zinc","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/nar/4.7.2321","doi":"https://doi.org/10.1093/nar/4.7.2321","is_oa":false,"landing_page_url":"https://doi.org/10.1093/nar/4.7.2321","pdf_url":null,"source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:232905","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC342569","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:342569","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/342569","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Res","raw_type":"Text"},{"id":"pmid:909778","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/909778","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:232905","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC342569","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W1967669069","https://openalex.org/W2016264581","https://openalex.org/W2019014169","https://openalex.org/W2021174446","https://openalex.org/W2032107182","https://openalex.org/W2034979068","https://openalex.org/W2039852023","https://openalex.org/W2053724590","https://openalex.org/W2074199903"],"related_works":["https://openalex.org/W2034979068","https://openalex.org/W2052576003","https://openalex.org/W1980771900","https://openalex.org/W2012942174","https://openalex.org/W2059519670","https://openalex.org/W56647703","https://openalex.org/W1994731245","https://openalex.org/W2018655094","https://openalex.org/W2090027953","https://openalex.org/W1969797781"],"abstract_inverted_index":{"Zinc/acetylacetone/pyridine":[0],"treatment":[1],"has":[2,40],"been":[3,41],"designed":[4],"as":[5,43],"a":[6,44],"very":[7],"efficient":[8],"method":[9],"for":[10,47],"removal":[11,50],"of":[12,49,51],"2,2,2,-trichloroethyl":[13],"group":[14],"from":[15],"phosphoesters.":[16],"Internucleotide":[17],"and":[18],"terminal":[19],"2,2,2-trichloroethylphosphotriesters":[20],"were":[21],"transformed":[22],"to":[23],"corresponding":[24],"diesters":[25],"quantitatively.":[26],"Much":[27],"less":[28],"reactive":[29],"2,2,2-trichloroethylphosphodiesters":[30],"produced":[31],"monoesters":[32],"with":[33],"ca.":[34],"90%":[35],"yield.":[36],"31P":[37],"NMR":[38],"spectroscopy":[39],"proposed":[42],"new":[45],"tool":[46],"analysis":[48],"internucleotide":[52],"phosphate":[53],"protecting":[54],"groups-a":[55],"crucial":[56],"step":[57],"in":[58],"oligonucleotides":[59],"synthesis":[60],"via":[61],"phosphotriester":[62],"approach.":[63]},"counts_by_year":[{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}