{"id":"https://openalex.org/W2085656274","doi":"https://doi.org/10.1111/are.12198","title":"In vitroeffect of pituitary, interrenal and gonadal hormones on vitellogenin synthesis in primary hepatocyte cultures ofChalcalburnus tarichi","display_name":"In vitroeffect of pituitary, interrenal and gonadal hormones on vitellogenin synthesis in primary hepatocyte cultures ofChalcalburnus tarichi","publication_year":2013,"publication_date":"2013-04-17","ids":{"openalex":"https://openalex.org/W2085656274","doi":"https://doi.org/10.1111/are.12198","mag":"2085656274"},"language":"en","primary_location":{"id":"doi:10.1111/are.12198","doi":"https://doi.org/10.1111/are.12198","is_oa":true,"landing_page_url":"https://doi.org/10.1111/are.12198","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/are.12198","source":{"id":"https://openalex.org/S185347631","display_name":"Aquaculture Research","issn_l":"1355-557X","issn":["1355-557X","1365-2109"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","jufo-1","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Aquaculture Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/are.12198","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073468511","display_name":"Ahmet Regaib O\u011fuz","orcid":"https://orcid.org/0000-0001-6431-0508","observed_orcids":["https://orcid.org/0000-0001-6431-0508"]},"institutions":[{"id":"https://openalex.org/I118567650","display_name":"Van Y\u00fcz\u00fcnc\u00fc Y\u0131l \u00dcniversitesi","ror":"https://ror.org/041jyzp61","country_code":"TR","type":"education","lineage":["https://openalex.org/I118567650"]}],"countries":["TR"],"is_corresponding":true,"raw_author_name":"Ahmet R O\u011fuz","raw_affiliation_strings":["Department of Biology; Faculty of Science; Y\u00fcz\u00fcnc\u00fc Y\u0131l University; Van Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology; Faculty of Science; Y\u00fcz\u00fcnc\u00fc Y\u0131l University; Van Turkey","institution_ids":["https://openalex.org/I118567650"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049430580","display_name":"G\u00fcler \u00dcnal","orcid":"https://orcid.org/0000-0001-5920-6693","observed_orcids":["https://orcid.org/0000-0001-5920-6693"]},"institutions":[{"id":"https://openalex.org/I118567650","display_name":"Van Y\u00fcz\u00fcnc\u00fc Y\u0131l \u00dcniversitesi","ror":"https://ror.org/041jyzp61","country_code":"TR","type":"education","lineage":["https://openalex.org/I118567650"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"G\u00fcler \u00dcnal","raw_affiliation_strings":["Department of Biology; Faculty of Science; Y\u00fcz\u00fcnc\u00fc Y\u0131l University; Van Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology; Faculty of Science; Y\u00fcz\u00fcnc\u00fc Y\u0131l University; Van Turkey","institution_ids":["https://openalex.org/I118567650"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5073468511"],"corresponding_institution_ids":["https://openalex.org/I118567650"],"apc_list":{"value":2700,"currency":"USD","value_usd":2700},"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.11763085,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"46","issue":"2","first_page":"482","last_page":"491"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11505","display_name":"Reproductive biology and impacts on aquatic species","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1314","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11505","display_name":"Reproductive biology and impacts on aquatic species","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1314","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10450","display_name":"Aquaculture Nutrition and Growth","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1104","display_name":"Aquatic Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vitellogenin-synthesis","display_name":"vitellogenin synthesis","score":0.9940000176429749},{"id":"https://openalex.org/keywords/chalcalburnus-tarichi","display_name":"Chalcalburnus tarichi","score":0.9359999895095825},{"id":"https://openalex.org/keywords/estradiol","display_name":"estradiol","score":0.9409999847412109},{"id":"https://openalex.org/keywords/progesterone","display_name":"progesterone","score":0.9649999737739563},{"id":"https://openalex.org/keywords/insulin","display_name":"insulin","score":0.9860000014305115},{"id":"https://openalex.org/keywords/11-deoxycortisol","display_name":"11-deoxycortisol","score":0.9929999709129333},{"id":"https://openalex.org/keywords/hepatocytes","display_name":"hepatocytes","score":0.7450000047683716},{"id":"https://openalex.org/keywords/yolk-proteins","display_name":"egg yolk proteins","score":0.6790000200271606},{"id":"https://openalex.org/keywords/fish-reproduction","display_name":"fish reproduction","score":0.5199999809265137},{"id":"https://openalex.org/keywords/hormone-interaction","display_name":"hormone crosstalk","score":0.38499999046325684},{"id":"https://openalex.org/keywords/vitellogenesis","display_name":"vitellogenesis","score":0.628000020980835}],"concepts":[{"id":"https://openalex.org/C2779078696","wikidata":"https://www.wikidata.org/wiki/Q83134957","display_name":"Vitellogenin","level":3,"score":0.9739976525306702},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8051450252532959},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7424171566963196},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7060574293136597},{"id":"https://openalex.org/C2776200302","wikidata":"https://www.wikidata.org/wiki/Q827450","display_name":"Hepatocyte","level":3,"score":0.6910156011581421},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.6877637505531311},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.5569507479667664},{"id":"https://openalex.org/C2778891732","wikidata":"https://www.wikidata.org/wiki/Q2751223","display_name":"Carp","level":3,"score":0.5124495625495911},{"id":"https://openalex.org/C2781321622","wikidata":"https://www.wikidata.org/wiki/Q181409","display_name":"Yolk","level":2,"score":0.500309944152832},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.13952720165252686},{"id":"https://openalex.org/C2909208804","wikidata":"https://www.wikidata.org/wiki/Q127282","display_name":"Fish <Actinopterygii>","level":2,"score":0.09961485862731934},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.058171868324279785},{"id":"https://openalex.org/C505870484","wikidata":"https://www.wikidata.org/wiki/Q180538","display_name":"Fishery","level":1,"score":0.0},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1111/are.12198","doi":"https://doi.org/10.1111/are.12198","is_oa":true,"landing_page_url":"https://doi.org/10.1111/are.12198","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/are.12198","source":{"id":"https://openalex.org/S185347631","display_name":"Aquaculture Research","issn_l":"1355-557X","issn":["1355-557X","1365-2109"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","jufo-1","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Aquaculture Research","raw_type":"journal-article"},{"id":"pmh:82b86834-8980-4547-9c74-be0d2d4064bc","doi":null,"is_oa":false,"landing_page_url":"https://avesis.yyu.edu.tr/publication/details/82b86834-8980-4547-9c74-be0d2d4064bc/oai","pdf_url":null,"source":{"id":"https://openalex.org/S7407055328","display_name":"Van Y\u00fcz\u00fcnc\u00fc Y\u0131l University Academic Data Management System","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1111/are.12198","doi":"https://doi.org/10.1111/are.12198","is_oa":true,"landing_page_url":"https://doi.org/10.1111/are.12198","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/are.12198","source":{"id":"https://openalex.org/S185347631","display_name":"Aquaculture Research","issn_l":"1355-557X","issn":["1355-557X","1365-2109"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","jufo-1","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Aquaculture Research","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2085656274.pdf","grobid_xml":"https://content.openalex.org/works/W2085656274.grobid-xml"},"referenced_works_count":36,"referenced_works":["https://openalex.org/W1040762224","https://openalex.org/W1966584280","https://openalex.org/W1975968709","https://openalex.org/W1983115253","https://openalex.org/W1983853043","https://openalex.org/W1991744718","https://openalex.org/W1995790544","https://openalex.org/W2005231025","https://openalex.org/W2008960451","https://openalex.org/W2012939923","https://openalex.org/W2014919987","https://openalex.org/W2015020209","https://openalex.org/W2029409956","https://openalex.org/W2029859952","https://openalex.org/W2042633995","https://openalex.org/W2046595616","https://openalex.org/W2059640346","https://openalex.org/W2066701282","https://openalex.org/W2070751612","https://openalex.org/W2071160969","https://openalex.org/W2072482644","https://openalex.org/W2073657931","https://openalex.org/W2082319814","https://openalex.org/W2087333651","https://openalex.org/W2123491474","https://openalex.org/W2131699244","https://openalex.org/W2142594979","https://openalex.org/W2149869551","https://openalex.org/W2151730777","https://openalex.org/W2154783755","https://openalex.org/W2155656951","https://openalex.org/W2161122497","https://openalex.org/W2162768051","https://openalex.org/W2166188229","https://openalex.org/W2528061834","https://openalex.org/W6658333003"],"related_works":["https://openalex.org/W791028987","https://openalex.org/W2131367927","https://openalex.org/W2087333651","https://openalex.org/W1959364954","https://openalex.org/W2008960451","https://openalex.org/W2065463796","https://openalex.org/W2082319814","https://openalex.org/W1990229292","https://openalex.org/W2087279844","https://openalex.org/W2046595616"],"abstract_inverted_index":{"Vitellogenin":[0,95],"(Vtg)":[1],"is":[2],"an":[3,115],"important":[4,181],"precursor":[5],"yolk":[6],"protein":[7],"in":[8,20,51,65,82,103,120,134,139,186],"egg-laying":[9],"vertebrates,":[10],"including":[11],"fish.":[12],"The":[13,61,78],"17\u03b2-oestradiol":[14],"(E2)":[15],"plays":[16],"a":[17,121,143,173],"crucial":[18],"role":[19,35],"the":[21,33,66,90,100,110,179],"Vtg":[22,29,52,64,118,145,151,170,184],"synthesis;":[23],"moreover,":[24],"certain":[25],"hormones":[26,50,107,182],"can":[27],"stimulate":[28],"synthesis.":[30],"We":[31],"investigated":[32],"possible":[34],"of":[36,63,92],"E2,":[37],"carp":[38],"recombinant":[39],"growth":[40],"hormone":[41],"(crGH),":[42],"insulin":[43],"(Ins),":[44],"progesterone":[45],"(P4)":[46],"and":[47,128,176],"11-deoxycortisol":[48],"(11-DOC)":[49],"synthesis":[53,119,185],"on":[54,117,166],"primary":[55],"juvenile":[56,187],"Chalcalburnus":[57],"tarichi":[58,189],"hepatocyte":[59,190],"culture.":[60,191],"amount":[62],"medium":[67],"was":[68,97,147],"measured":[69],"at":[70],"2-day":[71],"intervals":[72],"using":[73],"enzyme-linked":[74],"immunosorbent":[75],"assay":[76],"(ELISA).":[77],"hepatocytes":[79,135,154],"were":[80,155],"maintained":[81],"culture":[83],"for":[84,183],"more":[85],"than":[86],"2":[87],"weeks":[88],"without":[89],"addition":[91],"serum":[93],"components.":[94],"localization":[96],"visualized":[98],"with":[99,137,141,150,157,168],"immunofluorescence":[101],"method":[102],"E2-supplemented":[104],"hepatocytes.":[105],"Among":[106],"applied":[108],"to":[109,162],"culture,":[111],"only":[112],"E2":[113,138,158,175],"had":[114,130],"influence":[116],"time-dependent":[122],"manner,":[123],"while":[124],"crGH,":[125],"Ins,":[126],"P4":[127,160,177],"11-DOC":[129],"no":[131],"effect.":[132],"However,":[133],"stimulated":[136,156],"combination":[140],"P4,":[142],"lower":[144],"production":[146],"seen":[148],"compared":[149],"produced":[152],"when":[153],"alone.":[159],"proved":[161],"have":[163],"potentiating":[164],"effects":[165],"co-treatment":[167],"E2-induced":[169],"production.":[171],"As":[172],"result,":[174],"are":[178],"most":[180],"C.":[188]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2016-06-24T00:00:00"}