{"id":"https://openalex.org/W2085517430","doi":"https://doi.org/10.1111/j.1751-1097.1979.tb07749.x","title":"SPATIAL ARRANGEMENT OF RHODOPSIN IN THE DISK MEMBRANE AS STUDIED BY ENZYMATIC LABELING*","display_name":"SPATIAL ARRANGEMENT OF RHODOPSIN IN THE DISK MEMBRANE AS STUDIED BY ENZYMATIC LABELING*","publication_year":1979,"publication_date":"1979-04-01","ids":{"openalex":"https://openalex.org/W2085517430","doi":"https://doi.org/10.1111/j.1751-1097.1979.tb07749.x","mag":"2085517430","pmid":"https://pubmed.ncbi.nlm.nih.gov/451008"},"language":"en","primary_location":{"id":"doi:10.1111/j.1751-1097.1979.tb07749.x","doi":"https://doi.org/10.1111/j.1751-1097.1979.tb07749.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1751-1097.1979.tb07749.x","pdf_url":null,"source":{"id":"https://openalex.org/S61245073","display_name":"Photochemistry and Photobiology","issn_l":"0031-8655","issn":["0031-8655","1751-1097"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Photochemistry and Photobiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113547785","display_name":"Alois J. Adams","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210139686","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210139686"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alois J. Adams","raw_affiliation_strings":["Laboratory of Vision Research, National Eye Institute, National Institutes of Health, US. Department of Health, Education and Welfare, Bethesda. MU 20014. U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Vision Research, National Eye Institute, National Institutes of Health, US. Department of Health, Education and Welfare, Bethesda. MU 20014. U.S.A","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210139686"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009790454","display_name":"Robert L. Somers","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210139686","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210139686"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert L. Somers","raw_affiliation_strings":["Laboratory of Vision Research, National Eye Institute, National Institutes of Health, US. Department of Health, Education and Welfare, Bethesda. MU 20014. U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Vision Research, National Eye Institute, National Institutes of Health, US. Department of Health, Education and Welfare, Bethesda. MU 20014. U.S.A","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210139686"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002507714","display_name":"Hitoshi Shichi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210139686","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210139686"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hitoshi Shichi","raw_affiliation_strings":["Laboratory of Vision Research, National Eye Institute, National Institutes of Health, US. Department of Health, Education and Welfare, Bethesda. MU 20014. U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Vision Research, National Eye Institute, National Institutes of Health, US. Department of Health, Education and Welfare, Bethesda. MU 20014. U.S.A","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210139686"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4330,"currency":"USD","value_usd":4330},"apc_paid":null,"fwci":3.0035,"has_fulltext":false,"cited_by_count":28,"citation_normalized_percentile":{"value":0.91914147,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":null,"biblio":{"volume":"29","issue":"4","first_page":"687","last_page":"692"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12236","display_name":"Photoreceptor and optogenetics research","score":0.8115000128746033,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12236","display_name":"Photoreceptor and optogenetics research","score":0.8115000128746033,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.0835999995470047,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.0568000003695488,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rhodopsin","display_name":"rhodopsin","score":0.9980000257492065},{"id":"https://openalex.org/keywords/transmembrane-proteins","display_name":"transmembrane proteins","score":0.7979999780654907},{"id":"https://openalex.org/keywords/glycosylation","display_name":"glycosylation","score":0.7599999904632568},{"id":"https://openalex.org/keywords/galactose","display_name":"galactose","score":0.578000009059906},{"id":"https://openalex.org/keywords/galactosyltransferase","display_name":"galactosyltransferase","score":0.8610000014305115},{"id":"https://openalex.org/keywords/phosphorylation-sites","display_name":"phosphorylation sites","score":0.6639999747276306},{"id":"https://openalex.org/keywords/concanavalin-a-binding","display_name":"concanavalin A binding","score":0.7409999966621399},{"id":"https://openalex.org/keywords/bovine-retina","display_name":"bovine retina","score":0.7440000176429749},{"id":"https://openalex.org/keywords/visual-pigments","display_name":"visual pigments","score":0.5809999704360962}],"concepts":[{"id":"https://openalex.org/C202033177","wikidata":"https://www.wikidata.org/wiki/Q423107","display_name":"Rhodopsin","level":3,"score":0.9199103116989136},{"id":"https://openalex.org/C2780895608","wikidata":"https://www.wikidata.org/wiki/Q5517847","display_name":"Galactosyltransferase","level":3,"score":0.6493545770645142},{"id":"https://openalex.org/C64584667","wikidata":"https://www.wikidata.org/wiki/Q161179","display_name":"Pigment","level":2,"score":0.6072201728820801},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6024398803710938},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.5327354073524475},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.5025572776794434},{"id":"https://openalex.org/C24530287","wikidata":"https://www.wikidata.org/wiki/Q424204","display_name":"Transmembrane protein","level":3,"score":0.4985692501068115},{"id":"https://openalex.org/C19869320","wikidata":"https://www.wikidata.org/wiki/Q419277","display_name":"Concanavalin A","level":3,"score":0.486460417509079},{"id":"https://openalex.org/C11960822","wikidata":"https://www.wikidata.org/wiki/Q242736","display_name":"Phosphorylation","level":2,"score":0.46965375542640686},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.45866715908050537},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.4519179165363312},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.35885822772979736},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.22533383965492249},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.22300684452056885},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0941905677318573},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008566","descriptor_name":"Membranes","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D010786","descriptor_name":"Photoreceptor Cells","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":true},{"descriptor_ui":"D011494","descriptor_name":"Protein Kinases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012168","descriptor_name":"Retinal Pigments","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012243","descriptor_name":"Rhodopsin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013379","descriptor_name":"Substrate Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1751-1097.1979.tb07749.x","doi":"https://doi.org/10.1111/j.1751-1097.1979.tb07749.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1751-1097.1979.tb07749.x","pdf_url":null,"source":{"id":"https://openalex.org/S61245073","display_name":"Photochemistry and Photobiology","issn_l":"0031-8655","issn":["0031-8655","1751-1097"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Photochemistry and Photobiology","raw_type":"journal-article"},{"id":"pmid:451008","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/451008","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Photochemistry and photobiology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W1538349558","https://openalex.org/W1571668808","https://openalex.org/W1964699887","https://openalex.org/W1967788950","https://openalex.org/W1985592104","https://openalex.org/W1990744815","https://openalex.org/W1992319969","https://openalex.org/W2006011247","https://openalex.org/W2015836797","https://openalex.org/W2017344454","https://openalex.org/W2027494861","https://openalex.org/W2046800237","https://openalex.org/W2050292589","https://openalex.org/W2056755246","https://openalex.org/W2061148567","https://openalex.org/W2070248937","https://openalex.org/W2080347067","https://openalex.org/W2084076958","https://openalex.org/W2090807012","https://openalex.org/W2161384920","https://openalex.org/W2166645665","https://openalex.org/W2171012193"],"related_works":["https://openalex.org/W2110317958","https://openalex.org/W2092354358","https://openalex.org/W1996370268","https://openalex.org/W123575697","https://openalex.org/W1533788848","https://openalex.org/W2015836797","https://openalex.org/W2050606273","https://openalex.org/W2058527729","https://openalex.org/W2001662753","https://openalex.org/W2050207168"],"abstract_inverted_index":{"Abstract\u2014Intact":[0],"disks":[1,34,71],"prepared":[2],"from":[3],"fresh":[4],"bovine":[5],"retinas":[6],"were":[7,35,72],"phosphorylated":[8],"with":[9,74,101],"\u03b3\u2010[32P]\u2010ATP":[10],"and":[11,23,37,43,76,78,82,110],"highly":[12],"purified":[13,24,28],"rhodopsin":[14,79,96],"kinase.":[15],"After":[16],"regeneration.":[17],"the":[18,39,58,61,65,69,88,106,115],"visual":[19],"pigment":[20,29],"was":[21,41,80,85],"cxtracted":[22],"on":[25,105,114],"ECTEOLA\u2010cellulose.":[26],"The":[27,50],"contained":[30],"[32P]\u2010radioactivity.":[31],"When":[32,68],"intact":[33],"frozen":[36],"thawed.":[38],"membrane":[40],"inverted":[42,70],"became":[44],"capable":[45],"of":[46,63],"binding":[47],"concanavalin":[48],"A.":[49],"inversion":[51],"process":[52],"could":[53],"be":[54],"followed":[55],"by":[56,60],"measuring":[57],"entrapment":[59],"disk":[62],"[3H]\u2010inulin.":[64],"impermeable":[66],"polysaccharide.":[67],"incubated":[73],"UDP\u2010[3H]\u2010galactose":[75],"galactosyltransferase":[77],"extracted":[81],"purified.":[83],"[3H]\u2010gahctose":[84],"incorporated":[86],"into":[87],"pigment.":[89],"From":[90],"these":[91],"results":[92],"we":[93],"conclude":[94],"that":[95],"is":[97],"a":[98],"transmembrane":[99],"protein":[100],"its":[102,111],"carbohydrate":[103],"moiety":[104],"internal":[107],"(intradiscal)":[108],"surface":[109,118],"phosphorylation":[112],"sites":[113],"external":[116],"(interdiscal)":[117]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
