{"id":"https://openalex.org/W2085488689","doi":"https://doi.org/10.1016/j.bmcl.2012.01.027","title":"Hit to lead SAR study on benzoxazole derivatives for an NPY Y5 antagonist","display_name":"Hit to lead SAR study on benzoxazole derivatives for an NPY Y5 antagonist","publication_year":2012,"publication_date":"2012-01-18","ids":{"openalex":"https://openalex.org/W2085488689","doi":"https://doi.org/10.1016/j.bmcl.2012.01.027","mag":"2085488689","pmid":"https://pubmed.ncbi.nlm.nih.gov/22300657"},"language":"en","primary_location":{"id":"doi:10.1016/j.bmcl.2012.01.027","doi":"https://doi.org/10.1016/j.bmcl.2012.01.027","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bmcl.2012.01.027","pdf_url":null,"source":{"id":"https://openalex.org/S30970080","display_name":"Bioorganic & Medicinal Chemistry Letters","issn_l":"0960-894X","issn":["0960-894X","1464-3405"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioorganic & Medicinal Chemistry Letters","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018019898","display_name":"Naoki Omori","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210118477","display_name":"Shionogi (Japan)","ror":"https://ror.org/01v3bqg10","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210118477"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Naoki Omori","raw_affiliation_strings":["Medicinal Research Laboratories, Shionogi & Co., Ltd, 1-1, Futaba-cho 3-chome, Toyonaka, Osaka 561-0825, Japan. naoki.oomori@shionogi.co.jp","Medicinal Research Laboratories, Shionogi & Co., Ltd, 1-1, Futaba-cho 3-chome, Toyonaka, Osaka 561-0825, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicinal Research Laboratories, Shionogi & Co., Ltd, 1-1, Futaba-cho 3-chome, Toyonaka, Osaka 561-0825, Japan. naoki.oomori@shionogi.co.jp","institution_ids":["https://openalex.org/I4210118477"]},{"raw_affiliation_string":"Medicinal Research Laboratories, Shionogi & Co., Ltd, 1-1, Futaba-cho 3-chome, Toyonaka, Osaka 561-0825, Japan","institution_ids":["https://openalex.org/I4210118477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085205611","display_name":"Naoki Kouyama","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210118477","display_name":"Shionogi (Japan)","ror":"https://ror.org/01v3bqg10","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210118477"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Naoki Kouyama","raw_affiliation_strings":["Medicinal Research Laboratories, Shionogi & Co., Ltd, 1-1, Futaba-cho 3-chome, Toyonaka, Osaka 561-0825, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicinal Research Laboratories, Shionogi & Co., Ltd, 1-1, Futaba-cho 3-chome, Toyonaka, Osaka 561-0825, Japan","institution_ids":["https://openalex.org/I4210118477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062109041","display_name":"Akira Yukimasa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210118477","display_name":"Shionogi (Japan)","ror":"https://ror.org/01v3bqg10","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210118477"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Akira Yukimasa","raw_affiliation_strings":["Medicinal Research Laboratories, Shionogi & Co., Ltd, 1-1, Futaba-cho 3-chome, Toyonaka, Osaka 561-0825, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicinal Research Laboratories, Shionogi & Co., Ltd, 1-1, Futaba-cho 3-chome, Toyonaka, Osaka 561-0825, Japan","institution_ids":["https://openalex.org/I4210118477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113793905","display_name":"Kana Watanabe","orcid":"https://orcid.org/0000-0001-5139-5901","observed_orcids":["https://orcid.org/0000-0001-5139-5901"]},"institutions":[{"id":"https://openalex.org/I4210118477","display_name":"Shionogi (Japan)","ror":"https://ror.org/01v3bqg10","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210118477"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kana Watanabe","raw_affiliation_strings":["Medicinal Research Laboratories, Shionogi & Co., Ltd, 1-1, Futaba-cho 3-chome, Toyonaka, Osaka 561-0825, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicinal Research Laboratories, Shionogi & Co., Ltd, 1-1, Futaba-cho 3-chome, Toyonaka, Osaka 561-0825, Japan","institution_ids":["https://openalex.org/I4210118477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112532768","display_name":"Yasunori Yokota","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210118477","display_name":"Shionogi (Japan)","ror":"https://ror.org/01v3bqg10","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210118477"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasunori Yokota","raw_affiliation_strings":["Medicinal Research Laboratories, Shionogi & Co., Ltd, 1-1, Futaba-cho 3-chome, Toyonaka, Osaka 561-0825, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicinal Research Laboratories, Shionogi & Co., Ltd, 1-1, Futaba-cho 3-chome, Toyonaka, Osaka 561-0825, Japan","institution_ids":["https://openalex.org/I4210118477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045039935","display_name":"Hideki Tanioka","orcid":"https://orcid.org/0009-0008-7736-8387","observed_orcids":["https://orcid.org/0009-0008-7736-8387"]},"institutions":[{"id":"https://openalex.org/I4210118477","display_name":"Shionogi (Japan)","ror":"https://ror.org/01v3bqg10","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210118477"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hideki Tanioka","raw_affiliation_strings":["Medicinal Research Laboratories, Shionogi & Co., Ltd, 1-1, Futaba-cho 3-chome, Toyonaka, Osaka 561-0825, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicinal Research Laboratories, Shionogi & Co., Ltd, 1-1, Futaba-cho 3-chome, Toyonaka, Osaka 561-0825, Japan","institution_ids":["https://openalex.org/I4210118477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086371981","display_name":"Hirohide Nambu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210118477","display_name":"Shionogi (Japan)","ror":"https://ror.org/01v3bqg10","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210118477"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hirohide Nambu","raw_affiliation_strings":["Medicinal Research Laboratories, Shionogi & Co., Ltd, 1-1, Futaba-cho 3-chome, Toyonaka, Osaka 561-0825, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicinal Research Laboratories, Shionogi & Co., Ltd, 1-1, Futaba-cho 3-chome, Toyonaka, Osaka 561-0825, Japan","institution_ids":["https://openalex.org/I4210118477"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hideo Yukioka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210118477","display_name":"Shionogi (Japan)","ror":"https://ror.org/01v3bqg10","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210118477"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hideo Yukioka","raw_affiliation_strings":["Medicinal Research Laboratories, Shionogi & Co., Ltd, 1-1, Futaba-cho 3-chome, Toyonaka, Osaka 561-0825, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicinal Research Laboratories, Shionogi & Co., Ltd, 1-1, Futaba-cho 3-chome, Toyonaka, Osaka 561-0825, Japan","institution_ids":["https://openalex.org/I4210118477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000256757","display_name":"Norihito Sato","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210118477","display_name":"Shionogi (Japan)","ror":"https://ror.org/01v3bqg10","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210118477"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Norihito Sato","raw_affiliation_strings":["Drug Developmental Research Laboratories, Shionogi & Co., Ltd, 1-1, Futaba-cho 3-chome, Toyonaka, Osaka 561-0825, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug Developmental Research Laboratories, Shionogi & Co., Ltd, 1-1, Futaba-cho 3-chome, Toyonaka, Osaka 561-0825, Japan","institution_ids":["https://openalex.org/I4210118477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110434217","display_name":"Yukari Tanaka","orcid":"https://orcid.org/0000-0003-0369-715X","observed_orcids":["https://orcid.org/0000-0003-0369-715X"]},"institutions":[{"id":"https://openalex.org/I4210118477","display_name":"Shionogi (Japan)","ror":"https://ror.org/01v3bqg10","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210118477"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yukari Tanaka","raw_affiliation_strings":["Drug Developmental Research Laboratories, Shionogi & Co., Ltd, 1-1, Futaba-cho 3-chome, Toyonaka, Osaka 561-0825, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug Developmental Research Laboratories, Shionogi & Co., Ltd, 1-1, Futaba-cho 3-chome, Toyonaka, Osaka 561-0825, Japan","institution_ids":["https://openalex.org/I4210118477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066779407","display_name":"Kazutaka Sekiguchi","orcid":"https://orcid.org/0000-0002-8161-6346","observed_orcids":["https://orcid.org/0000-0002-8161-6346"]},"institutions":[{"id":"https://openalex.org/I4210118477","display_name":"Shionogi (Japan)","ror":"https://ror.org/01v3bqg10","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210118477"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazutaka Sekiguchi","raw_affiliation_strings":["Drug Developmental Research Laboratories, Shionogi & Co., Ltd, 1-1, Futaba-cho 3-chome, Toyonaka, Osaka 561-0825, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug Developmental Research Laboratories, Shionogi & Co., Ltd, 1-1, Futaba-cho 3-chome, Toyonaka, Osaka 561-0825, Japan","institution_ids":["https://openalex.org/I4210118477"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047956581","display_name":"Takayuki Okuno","orcid":"https://orcid.org/0000-0003-2521-7153","observed_orcids":["https://orcid.org/0000-0003-2521-7153"]},"institutions":[{"id":"https://openalex.org/I4210118477","display_name":"Shionogi (Japan)","ror":"https://ror.org/01v3bqg10","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210118477"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takayuki Okuno","raw_affiliation_strings":["Medicinal Research Laboratories, Shionogi & Co., Ltd, 1-1, Futaba-cho 3-chome, Toyonaka, Osaka 561-0825, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicinal Research Laboratories, Shionogi & Co., Ltd, 1-1, Futaba-cho 3-chome, Toyonaka, Osaka 561-0825, Japan","institution_ids":["https://openalex.org/I4210118477"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210118477"],"apc_list":{"value":3880,"currency":"USD","value_usd":3880},"apc_paid":null,"fwci":0.8601,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.661869,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"22","issue":"5","first_page":"2020","last_page":"2023"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.8012999892234802,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.8012999892234802,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10274","display_name":"Heterocyclic Compound Synthesis and Bioactivity","score":0.1160999983549118,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.019899999722838402,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/benzoxazole-derivatives","display_name":"benzoxazole derivatives","score":0.9369999766349792},{"id":"https://openalex.org/keywords/neuropeptide-y","display_name":"neuropeptide Y","score":0.8799999952316284},{"id":"https://openalex.org/keywords/structure-activity-relationship","display_name":"structure-activity relationship","score":0.8349999785423279},{"id":"https://openalex.org/keywords/hit-to-lead","display_name":"hit-to-lead optimization","score":0.8330000042915344},{"id":"https://openalex.org/keywords/food-intake-reduction","display_name":"hypophagia","score":0.9539999961853027},{"id":"https://openalex.org/keywords/weight-gain","display_name":"weight gain","score":0.7129999995231628}],"concepts":[{"id":"https://openalex.org/C2778047396","wikidata":"https://www.wikidata.org/wiki/Q761111","display_name":"Benzoxazole","level":2,"score":0.9417238235473633},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8875542879104614},{"id":"https://openalex.org/C2776885963","wikidata":"https://www.wikidata.org/wiki/Q245204","display_name":"Antagonist","level":3,"score":0.8123294115066528},{"id":"https://openalex.org/C2777752112","wikidata":"https://www.wikidata.org/wiki/Q903238","display_name":"Lead compound","level":3,"score":0.5348637700080872},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.45085304975509644},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.3354494869709015},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.26732784509658813},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.17942622303962708},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.10385558009147644},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.06583324074745178},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001583","descriptor_name":"Benzoxazoles","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D001583","descriptor_name":"Benzoxazoles","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D001583","descriptor_name":"Benzoxazoles","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D001583","descriptor_name":"Benzoxazoles","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D001835","descriptor_name":"Body Weight","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004435","descriptor_name":"Eating","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013329","descriptor_name":"Structure-Activity Relationship","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017476","descriptor_name":"Receptors, Neuropeptide Y","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D017476","descriptor_name":"Receptors, Neuropeptide Y","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019440","descriptor_name":"Anti-Obesity Agents","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D019440","descriptor_name":"Anti-Obesity Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D019440","descriptor_name":"Anti-Obesity Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D019440","descriptor_name":"Anti-Obesity Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.bmcl.2012.01.027","doi":"https://doi.org/10.1016/j.bmcl.2012.01.027","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bmcl.2012.01.027","pdf_url":null,"source":{"id":"https://openalex.org/S30970080","display_name":"Bioorganic & Medicinal Chemistry Letters","issn_l":"0960-894X","issn":["0960-894X","1464-3405"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioorganic & Medicinal Chemistry Letters","raw_type":"journal-article"},{"id":"pmid:22300657","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22300657","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioorganic & medicinal chemistry letters","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.6240000128746033,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332162","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W1967220156","https://openalex.org/W1982474971","https://openalex.org/W1991924547","https://openalex.org/W2015301110","https://openalex.org/W2029975466","https://openalex.org/W2032354629","https://openalex.org/W2039682636","https://openalex.org/W2058961547","https://openalex.org/W2059186835","https://openalex.org/W2066504001","https://openalex.org/W2067042909","https://openalex.org/W2075221169","https://openalex.org/W2078877488","https://openalex.org/W2079201209","https://openalex.org/W2085051895","https://openalex.org/W2089553864","https://openalex.org/W2125312207","https://openalex.org/W2157127393","https://openalex.org/W2318945865","https://openalex.org/W2949211793","https://openalex.org/W2949835147"],"related_works":["https://openalex.org/W2060214459","https://openalex.org/W2032354629","https://openalex.org/W1988975379","https://openalex.org/W1978604153","https://openalex.org/W2911532265","https://openalex.org/W1967148428","https://openalex.org/W2267258300","https://openalex.org/W1997173035","https://openalex.org/W2039682636","https://openalex.org/W1991227943"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}