{"id":"https://openalex.org/W2085271102","doi":"https://doi.org/10.1016/0012-1606(86)90302-7","title":"Characterization of myogenic cell lines derived by 5-azacytidine treatment","display_name":"Characterization of myogenic cell lines derived by 5-azacytidine treatment","publication_year":1986,"publication_date":"1986-10-01","ids":{"openalex":"https://openalex.org/W2085271102","doi":"https://doi.org/10.1016/0012-1606(86)90302-7","mag":"2085271102","pmid":"https://pubmed.ncbi.nlm.nih.gov/2428680"},"language":"en","primary_location":{"id":"doi:10.1016/0012-1606(86)90302-7","doi":"https://doi.org/10.1016/0012-1606(86)90302-7","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0012-1606(86)90302-7","pdf_url":null,"source":{"id":"https://openalex.org/S136634221","display_name":"Developmental Biology","issn_l":"0012-1606","issn":["0012-1606","1095-564X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067014571","display_name":"Leonard Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Leonard Liu","raw_affiliation_strings":["USC Cancer Center, University of Southern California School of Medicine, Los Angeles, California 90033 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"USC Cancer Center, University of Southern California School of Medicine, Los Angeles, California 90033 USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109319762","display_name":"Maureen A. Harrington","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maureen Harrington","raw_affiliation_strings":["USC Cancer Center, University of Southern California School of Medicine, Los Angeles, California 90033 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"USC Cancer Center, University of Southern California School of Medicine, Los Angeles, California 90033 USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088347458","display_name":"Peter A. Jones","orcid":"https://orcid.org/0000-0001-8309-4767","observed_orcids":["https://orcid.org/0000-0001-8309-4767"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Peter A. Jones","raw_affiliation_strings":["USC Cancer Center, University of Southern California School of Medicine, Los Angeles, California 90033 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"USC Cancer Center, University of Southern California School of Medicine, Los Angeles, California 90033 USA","institution_ids":["https://openalex.org/I1174212"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5088347458"],"corresponding_institution_ids":["https://openalex.org/I1174212"],"apc_list":{"value":3550,"currency":"USD","value_usd":3550},"apc_paid":null,"fwci":0.3673,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.53808952,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"117","issue":"2","first_page":"331","last_page":"336"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.9634000062942505,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.9634000062942505,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":0.007899999618530273,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.004600000102072954,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/myogenic-cell-lines","display_name":"myogenic cell lines","score":0.8519999980926514},{"id":"https://openalex.org/keywords/azacitidine","display_name":"azacitidine","score":0.9940000176429749},{"id":"https://openalex.org/keywords/10t1-2-cells","display_name":"10T1/2 cells","score":0.878000020980835},{"id":"https://openalex.org/keywords/myotube-formation","display_name":"myotube formation","score":0.7020000219345093},{"id":"https://openalex.org/keywords/cell-fusion","display_name":"cell fusion","score":0.906000018119812},{"id":"https://openalex.org/keywords/5-methylcytosine","display_name":"5-methylcytosine","score":0.949999988079071},{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.7639999985694885},{"id":"https://openalex.org/keywords/myogenesis","display_name":"myogenesis","score":0.5889999866485596},{"id":"https://openalex.org/keywords/lineage-commitment","display_name":"lineage commitment","score":0.6980000138282776},{"id":"https://openalex.org/keywords/acetylcholine-induced-contraction","display_name":"acetylcholine-induced contraction","score":0.8059999942779541}],"concepts":[{"id":"https://openalex.org/C3763915","wikidata":"https://www.wikidata.org/wiki/Q3331437","display_name":"Myogenesis","level":3,"score":0.7823717594146729},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7820224761962891},{"id":"https://openalex.org/C92488253","wikidata":"https://www.wikidata.org/wiki/Q56592403","display_name":"Cell fusion","level":3,"score":0.7515491247177124},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.7069767713546753},{"id":"https://openalex.org/C36880943","wikidata":"https://www.wikidata.org/wiki/Q409458","display_name":"Creatine kinase","level":2,"score":0.6916033029556274},{"id":"https://openalex.org/C207200792","wikidata":"https://www.wikidata.org/wiki/Q428914","display_name":"Myocyte","level":2,"score":0.6345999240875244},{"id":"https://openalex.org/C60278653","wikidata":"https://www.wikidata.org/wiki/Q5008075","display_name":"C2C12","level":4,"score":0.5471488833427429},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.5170855522155762},{"id":"https://openalex.org/C90703135","wikidata":"https://www.wikidata.org/wiki/Q3287622","display_name":"Tissue culture","level":3,"score":0.49264460802078247},{"id":"https://openalex.org/C119795356","wikidata":"https://www.wikidata.org/wiki/Q407801","display_name":"Isozyme","level":3,"score":0.4406304955482483},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.436942994594574},{"id":"https://openalex.org/C113842279","wikidata":"https://www.wikidata.org/wiki/Q1873857","display_name":"Lymphoblast","level":3,"score":0.4132445156574249},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.40085268020629883},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3992604911327362},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.2720086872577667},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.23665818572044373},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.19499939680099487}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001374","descriptor_name":"Azacitidine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D002459","descriptor_name":"Cell Fusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003402","descriptor_name":"Creatine Kinase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007527","descriptor_name":"Isoenzymes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009132","descriptor_name":"Muscles","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0012-1606(86)90302-7","doi":"https://doi.org/10.1016/0012-1606(86)90302-7","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0012-1606(86)90302-7","pdf_url":null,"source":{"id":"https://openalex.org/S136634221","display_name":"Developmental Biology","issn_l":"0012-1606","issn":["0012-1606","1095-564X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Biology","raw_type":"journal-article"},{"id":"pmid:2428680","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2428680","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental biology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4937558107","display_name":"5-AZACYTIDINE INDUCED DIFFERENTIATION","funder_award_id":"R01CA039913","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W969821870","https://openalex.org/W1499922508","https://openalex.org/W1598605388","https://openalex.org/W1751117484","https://openalex.org/W1865658459","https://openalex.org/W1878410949","https://openalex.org/W1969934162","https://openalex.org/W1970823660","https://openalex.org/W1984757056","https://openalex.org/W1991556338","https://openalex.org/W1992288855","https://openalex.org/W1998918984","https://openalex.org/W2013850239","https://openalex.org/W2027782583","https://openalex.org/W2030417322","https://openalex.org/W2032455063","https://openalex.org/W2035123221","https://openalex.org/W2045411834","https://openalex.org/W2063141151","https://openalex.org/W2065977820","https://openalex.org/W2066022960","https://openalex.org/W2068417651","https://openalex.org/W2089829718","https://openalex.org/W2091602444","https://openalex.org/W2095900264","https://openalex.org/W2102080028","https://openalex.org/W2140855999","https://openalex.org/W2145750252","https://openalex.org/W2390806247","https://openalex.org/W6635593028","https://openalex.org/W6666061745","https://openalex.org/W6681292383"],"related_works":["https://openalex.org/W2027782583","https://openalex.org/W7096151192","https://openalex.org/W1865658459","https://openalex.org/W2065977820","https://openalex.org/W2036936539","https://openalex.org/W2118581355","https://openalex.org/W7098017453","https://openalex.org/W1992288855","https://openalex.org/W1993623493","https://openalex.org/W2225007130"],"abstract_inverted_index":null,"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}