{"id":"https://openalex.org/W2085210936","doi":"https://doi.org/10.1016/0091-3057(94)00346-7","title":"Antinociception following 1,3,-di-o-tolylguanidine, a selective \u03c3 receptor ligand","display_name":"Antinociception following 1,3,-di-o-tolylguanidine, a selective \u03c3 receptor ligand","publication_year":1995,"publication_date":"1995-04-01","ids":{"openalex":"https://openalex.org/W2085210936","doi":"https://doi.org/10.1016/0091-3057(94)00346-7","mag":"2085210936","pmid":"https://pubmed.ncbi.nlm.nih.gov/7617705"},"language":"en","primary_location":{"id":"doi:10.1016/0091-3057(94)00346-7","doi":"https://doi.org/10.1016/0091-3057(94)00346-7","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0091-3057(94)00346-7","pdf_url":null,"source":{"id":"https://openalex.org/S59685179","display_name":"Pharmacology Biochemistry and Behavior","issn_l":"0091-3057","issn":["0091-3057","1873-5177"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmacology Biochemistry and Behavior","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005776897","display_name":"Jeffrey S. Mogil","orcid":"https://orcid.org/0000-0003-1359-5720","observed_orcids":["https://orcid.org/0000-0003-1359-5720"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]},{"id":"https://openalex.org/I2803065977","display_name":"Portland VA Medical Center","ror":"https://ror.org/02v3txv81","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I2803065977","https://openalex.org/I4210144745"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey S. Mogil","raw_affiliation_strings":["Department of Psychiatry and Biobehavioral Sciences, Neuropsychiatric Institute, University of California, Los Angeles, Los Angeles, CA 90024 USA","Research Service (151 W), VA Medical Center, Portland OR 97201 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry and Biobehavioral Sciences, Neuropsychiatric Institute, University of California, Los Angeles, Los Angeles, CA 90024 USA","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"Research Service (151 W), VA Medical Center, Portland OR 97201 USA","institution_ids":["https://openalex.org/I2803065977"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108350763","display_name":"Wendy F. Sternberg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wendy F. Sternberg","raw_affiliation_strings":["Department of Psychology and Brain Research Institute, University of California, Los Angeles, Los Angeles, CA 90024 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology and Brain Research Institute, University of California, Los Angeles, Los Angeles, CA 90024 USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029621910","display_name":"Robert N. Pechnick","orcid":"https://orcid.org/0000-0002-2238-9964","observed_orcids":["https://orcid.org/0000-0002-2238-9964"]},"institutions":[{"id":"https://openalex.org/I121820613","display_name":"Louisiana State University","ror":"https://ror.org/05ect4e57","country_code":"US","type":"education","lineage":["https://openalex.org/I121820613"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert N. Pechnick","raw_affiliation_strings":["Department of Pharmacology, LSU Medical Center, New Orleans, LA 70119 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, LSU Medical Center, New Orleans, LA 70119 USA","institution_ids":["https://openalex.org/I121820613"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111624094","display_name":"John C. Liebeskind","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"John C. Liebeskind","raw_affiliation_strings":["Department of Psychology and Brain Research Institute, University of California, Los Angeles, Los Angeles, CA 90024 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology and Brain Research Institute, University of California, Los Angeles, Los Angeles, CA 90024 USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110530939","display_name":"Benjamin Kest","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Benjamin Kest","raw_affiliation_strings":["Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles 90024, USA","Department of Psychiatry & Biobehavioral Sciences, University of California, Los Angeles 90024, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles 90024, USA","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"Department of Psychiatry & Biobehavioral Sciences, University of California, Los Angeles 90024, USA","institution_ids":["https://openalex.org/I161318765"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5111624094"],"corresponding_institution_ids":["https://openalex.org/I161318765"],"apc_list":{"value":3650,"currency":"USD","value_usd":3650},"apc_paid":null,"fwci":0.7976,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.68505921,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"50","issue":"4","first_page":"587","last_page":"592"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13047","display_name":"Pharmacological Receptor Mechanisms and Effects","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13047","display_name":"Pharmacological Receptor Mechanisms and Effects","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sigma-receptors","display_name":"sigma receptors","score":0.9129999876022339},{"id":"https://openalex.org/keywords/1-3-di-o-tolylguanidine","display_name":"1,3-di-o-tolylguanidine","score":0.9769999980926514},{"id":"https://openalex.org/keywords/rimcazole","display_name":"rimcazole","score":0.8500000238418579},{"id":"https://openalex.org/keywords/antinociception","display_name":"antinociception","score":0.9769999980926514},{"id":"https://openalex.org/keywords/tail-withdrawal-latency","display_name":"tail withdrawal latency","score":0.9409999847412109},{"id":"https://openalex.org/keywords/thermal-nociception","display_name":"thermal nociception","score":0.6039999723434448},{"id":"https://openalex.org/keywords/hypothermia","display_name":"hypothermia","score":0.8859999775886536},{"id":"https://openalex.org/keywords/haloperidol","display_name":"haloperidol","score":0.7599999904632568},{"id":"https://openalex.org/keywords/naloxone","display_name":"naloxone","score":0.9190000295639038},{"id":"https://openalex.org/keywords/mk-801","display_name":"MK-801","score":0.9980000257492065},{"id":"https://openalex.org/keywords/receptor-selectivity","display_name":"receptor selectivity","score":0.5989999771118164}],"concepts":[{"id":"https://openalex.org/C67018056","wikidata":"https://www.wikidata.org/wiki/Q414896","display_name":"NMDA receptor","level":3,"score":0.7801255583763123},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.6532228589057922},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.6296420693397522},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.627139151096344},{"id":"https://openalex.org/C2778750930","wikidata":"https://www.wikidata.org/wiki/Q4540629","display_name":"(+)-Naloxone","level":4,"score":0.625143826007843},{"id":"https://openalex.org/C2776885963","wikidata":"https://www.wikidata.org/wiki/Q245204","display_name":"Antagonist","level":3,"score":0.6192023754119873},{"id":"https://openalex.org/C15490471","wikidata":"https://www.wikidata.org/wiki/Q2734305","display_name":"Nociception","level":3,"score":0.5339155793190002},{"id":"https://openalex.org/C2777389121","wikidata":"https://www.wikidata.org/wiki/Q81225","display_name":"Morphine","level":2,"score":0.5092005133628845},{"id":"https://openalex.org/C86811712","wikidata":"https://www.wikidata.org/wiki/Q410943","display_name":"Competitive antagonist","level":4,"score":0.49734237790107727},{"id":"https://openalex.org/C2778140631","wikidata":"https://www.wikidata.org/wiki/Q2026938","display_name":"Opiate","level":3,"score":0.4820604920387268},{"id":"https://openalex.org/C2780948584","wikidata":"https://www.wikidata.org/wiki/Q251347","display_name":"Haloperidol","level":3,"score":0.4757768213748932},{"id":"https://openalex.org/C116569031","wikidata":"https://www.wikidata.org/wiki/Q899107","display_name":"Ligand (biochemistry)","level":3,"score":0.46737140417099},{"id":"https://openalex.org/C61174792","wikidata":"https://www.wikidata.org/wiki/Q420510","display_name":"Glutamate receptor","level":3,"score":0.4581136107444763},{"id":"https://openalex.org/C2778122271","wikidata":"https://www.wikidata.org/wiki/Q410943","display_name":"Receptor antagonist","level":4,"score":0.4196416735649109},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.18094995617866516},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.17672017216682434},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.12034487724304199},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.08774632215499878}],"mesh":[{"descriptor_ui":"D000704","descriptor_name":"Analysis of Variance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006146","descriptor_name":"Guanidines","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010146","descriptor_name":"Pain","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D011930","descriptor_name":"Reaction Time","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017480","descriptor_name":"Receptors, sigma","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/0091-3057(94)00346-7","doi":"https://doi.org/10.1016/0091-3057(94)00346-7","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0091-3057(94)00346-7","pdf_url":null,"source":{"id":"https://openalex.org/S59685179","display_name":"Pharmacology Biochemistry and Behavior","issn_l":"0091-3057","issn":["0091-3057","1873-5177"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmacology Biochemistry and Behavior","raw_type":"journal-article"},{"id":"pmid:7617705","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7617705","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmacology, biochemistry, and behavior","raw_type":"Journal Article"},{"id":"mag:54181563","doi":null,"is_oa":false,"landing_page_url":"https://scholarship.haverford.edu/psychology_facpubs/176/","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G8060342168","display_name":"Research Training: Psychobiological Sciences","funder_award_id":"T32MH017140","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G8818127040","display_name":"BEHAVIORAL AND ELECTROPHYSIOLOGICAL STUDIES OF PAIN","funder_award_id":"R01NS007628","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"}],"funders":[{"id":"https://openalex.org/F4320307115","display_name":"Bristol-Myers Squibb","ror":"https://ror.org/00gtmwv55"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":64,"referenced_works":["https://openalex.org/W607389392","https://openalex.org/W1623883571","https://openalex.org/W1833595893","https://openalex.org/W1886668162","https://openalex.org/W1900414416","https://openalex.org/W1911515672","https://openalex.org/W1961011427","https://openalex.org/W1967547000","https://openalex.org/W1972190053","https://openalex.org/W1972388792","https://openalex.org/W1973750932","https://openalex.org/W1974432965","https://openalex.org/W1975216040","https://openalex.org/W1976554671","https://openalex.org/W1977829278","https://openalex.org/W1980532251","https://openalex.org/W1985990221","https://openalex.org/W1986694311","https://openalex.org/W1990111277","https://openalex.org/W1992763610","https://openalex.org/W1997222763","https://openalex.org/W1999523741","https://openalex.org/W2006917325","https://openalex.org/W2008858337","https://openalex.org/W2027509785","https://openalex.org/W2029606971","https://openalex.org/W2031242571","https://openalex.org/W2035803376","https://openalex.org/W2037053212","https://openalex.org/W2037351445","https://openalex.org/W2038604736","https://openalex.org/W2042145943","https://openalex.org/W2044136878","https://openalex.org/W2044185289","https://openalex.org/W2044737988","https://openalex.org/W2045678324","https://openalex.org/W2046516880","https://openalex.org/W2054968525","https://openalex.org/W2055112607","https://openalex.org/W2061633232","https://openalex.org/W2083182773","https://openalex.org/W2089108699","https://openalex.org/W2091061257","https://openalex.org/W2093768149","https://openalex.org/W2095109704","https://openalex.org/W2100040827","https://openalex.org/W2128754068","https://openalex.org/W2143187803","https://openalex.org/W2158767242","https://openalex.org/W2169700045","https://openalex.org/W2201897764","https://openalex.org/W2262915195","https://openalex.org/W2266407629","https://openalex.org/W2402866639","https://openalex.org/W2404009231","https://openalex.org/W2410697169","https://openalex.org/W2410888088","https://openalex.org/W2439238355","https://openalex.org/W4300308322","https://openalex.org/W4406985827","https://openalex.org/W6641054086","https://openalex.org/W6648584678","https://openalex.org/W6657155780","https://openalex.org/W6714979412"],"related_works":["https://openalex.org/W54181563","https://openalex.org/W2055112607","https://openalex.org/W2262915195","https://openalex.org/W1979055305","https://openalex.org/W1974139721","https://openalex.org/W1911515672","https://openalex.org/W2090999647","https://openalex.org/W1992517587","https://openalex.org/W2065276535","https://openalex.org/W7098069679"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}