{"id":"https://openalex.org/W2085030367","doi":"https://doi.org/10.1016/j.arcmed.2011.02.003","title":"Distal Esophageal Hypercontractility Is Related to Abnormal Acid Exposure","display_name":"Distal Esophageal Hypercontractility Is Related to Abnormal Acid Exposure","publication_year":2011,"publication_date":"2011-02-01","ids":{"openalex":"https://openalex.org/W2085030367","doi":"https://doi.org/10.1016/j.arcmed.2011.02.003","mag":"2085030367","pmid":"https://pubmed.ncbi.nlm.nih.gov/21565622"},"language":"en","primary_location":{"id":"doi:10.1016/j.arcmed.2011.02.003","doi":"https://doi.org/10.1016/j.arcmed.2011.02.003","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.arcmed.2011.02.003","pdf_url":null,"source":{"id":"https://openalex.org/S157833918","display_name":"Archives of Medical Research","issn_l":"0066-6769","issn":["0066-6769","0188-0128","0188-4409","1873-5487"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of Medical Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055569325","display_name":"Julio C\u00e9sar Soto-P\u00e9rez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405261722","display_name":"Hospital Central Sur de Alta Especialidad PEMEX","ror":"https://ror.org/05ra54594","country_code":"MX","type":"healthcare","lineage":["https://openalex.org/I4405261722","https://openalex.org/I5447759"]},{"id":"https://openalex.org/I5447759","display_name":"Pemex (Mexico)","ror":"https://ror.org/040ek4035","country_code":"MX","type":"company","lineage":["https://openalex.org/I5447759"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Julio C\u00e9sar Soto-P\u00e9rez","raw_affiliation_strings":["Cl\u00ednica de Fisiolog\u00eda Digestiva del Hospital Metropolitano y Hospital de Alta Especialidad PEMEX SUR, Mexico, D.F., Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cl\u00ednica de Fisiolog\u00eda Digestiva del Hospital Metropolitano y Hospital de Alta Especialidad PEMEX SUR, Mexico, D.F., Mexico","institution_ids":["https://openalex.org/I4405261722","https://openalex.org/I5447759"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015797035","display_name":"Sergio R. Sobrino-Cossio","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210153971","display_name":"Instituto Nacional de Cancerolog\u00eda","ror":"https://ror.org/04z3afh10","country_code":"MX","type":"government","lineage":["https://openalex.org/I4210095685","https://openalex.org/I4210153971"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Sergio Sobrino-Coss\u00edo","raw_affiliation_strings":["Servicio de Endosopia, Instituto Nacional de Cancerolog\u00eda, Mexico, D.F., Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Servicio de Endosopia, Instituto Nacional de Cancerolog\u00eda, Mexico, D.F., Mexico","institution_ids":["https://openalex.org/I4210153971"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005579430","display_name":"Paul B. Higgins","orcid":"https://orcid.org/0000-0003-0882-623X","observed_orcids":["https://orcid.org/0000-0003-0882-623X"]},"institutions":[{"id":"https://openalex.org/I1289525096","display_name":"Texas Biomedical Research Institute","ror":"https://ror.org/00wbskb04","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289525096"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul B. Higgins","raw_affiliation_strings":["Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas","institution_ids":["https://openalex.org/I1289525096"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079020015","display_name":"Anthony Gean Comuzzie","orcid":"https://orcid.org/0000-0001-9345-157X","observed_orcids":["https://orcid.org/0000-0001-9345-157X"]},"institutions":[{"id":"https://openalex.org/I1289525096","display_name":"Texas Biomedical Research Institute","ror":"https://ror.org/00wbskb04","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289525096"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anthony G. Comuzzie","raw_affiliation_strings":["Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas","institution_ids":["https://openalex.org/I1289525096"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064910151","display_name":"Jose Antonio Vargas Romero","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jose Antonio Vargas Romero","raw_affiliation_strings":["Direcci\u00f3n M\u00e9dica, Nycomed SA de CV, Naucalpan, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Direcci\u00f3n M\u00e9dica, Nycomed SA de CV, Naucalpan, Mexico","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037309976","display_name":"Arturo Reding\u2010Bernal","orcid":"https://orcid.org/0000-0003-4318-181X","observed_orcids":["https://orcid.org/0000-0003-4318-181X"]},"institutions":[{"id":"https://openalex.org/I2802421035","display_name":"Hospital General de M\u00e9xico","ror":"https://ror.org/01php1d31","country_code":"MX","type":"healthcare","lineage":["https://openalex.org/I2802421035","https://openalex.org/I4210095685"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Arturo Reding-Bernal","raw_affiliation_strings":["Direcci\u00f3n de Investigaci\u00f3n, Hospital General de M\u00e9xico, Mexico, D.F., Mexico","Direcci\u00f3n de Investigaci\u00f3n, Hospital General de M\u00e9xico, M\u00e9xico D. F., M\u00e9xico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Direcci\u00f3n de Investigaci\u00f3n, Hospital General de M\u00e9xico, Mexico, D.F., Mexico","institution_ids":["https://openalex.org/I2802421035"]},{"raw_affiliation_string":"Direcci\u00f3n de Investigaci\u00f3n, Hospital General de M\u00e9xico, M\u00e9xico D. F., M\u00e9xico","institution_ids":["https://openalex.org/I2802421035"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014991831","display_name":"Juan Carlos L\u00f3pez-Alvarenga","orcid":"https://orcid.org/0000-0002-0966-8766","observed_orcids":["https://orcid.org/0000-0002-0966-8766"]},"institutions":[{"id":"https://openalex.org/I1289525096","display_name":"Texas Biomedical Research Institute","ror":"https://ror.org/00wbskb04","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289525096"]},{"id":"https://openalex.org/I2802421035","display_name":"Hospital General de M\u00e9xico","ror":"https://ror.org/01php1d31","country_code":"MX","type":"healthcare","lineage":["https://openalex.org/I2802421035","https://openalex.org/I4210095685"]}],"countries":["MX","US"],"is_corresponding":true,"raw_author_name":"Juan Carlos L\u00f3pez-Alvarenga","raw_affiliation_strings":["Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas","Direcci\u00f3n de Investigaci\u00f3n, Hospital General de M\u00e9xico, Mexico, D.F., Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas","institution_ids":["https://openalex.org/I1289525096"]},{"raw_affiliation_string":"Direcci\u00f3n de Investigaci\u00f3n, Hospital General de M\u00e9xico, Mexico, D.F., Mexico","institution_ids":["https://openalex.org/I2802421035"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5014991831"],"corresponding_institution_ids":["https://openalex.org/I1289525096","https://openalex.org/I2802421035"],"apc_list":{"value":3360,"currency":"USD","value_usd":3360},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.20800075,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"42","issue":"2","first_page":"104","last_page":"109"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10671","display_name":"Gastroesophageal reflux and treatments","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10671","display_name":"Gastroesophageal reflux and treatments","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10619","display_name":"Esophageal Cancer Research and Treatment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nutcracker-esophagus","display_name":"nutcracker esophagus","score":0.9440000057220459},{"id":"https://openalex.org/keywords/acid-exposure","display_name":"acid exposure","score":0.8450000286102295},{"id":"https://openalex.org/keywords/demeester-score","display_name":"DeMeester score","score":0.9679999947547913},{"id":"https://openalex.org/keywords/esophageal-motility-disorders","display_name":"esophageal motility disorders","score":0.8650000095367432},{"id":"https://openalex.org/keywords/lower-esophageal-sphincter","display_name":"lower esophageal sphincter","score":0.8539999723434448},{"id":"https://openalex.org/keywords/age","display_name":"age","score":0.3009999990463257},{"id":"https://openalex.org/keywords/proton-pump-inhibitors","display_name":"proton pump inhibitors","score":0.8659999966621399},{"id":"https://openalex.org/keywords/chest-pain","display_name":"chest pain","score":0.6809999942779541},{"id":"https://openalex.org/keywords/heartburn","display_name":"heartburn","score":0.9599999785423279}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6860843896865845},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.5969277024269104},{"id":"https://openalex.org/C2776462128","wikidata":"https://www.wikidata.org/wiki/Q537297","display_name":"Heartburn","level":4,"score":0.5872691869735718},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5201966166496277},{"id":"https://openalex.org/C2777819096","wikidata":"https://www.wikidata.org/wiki/Q173710","display_name":"Esophagus","level":2,"score":0.45336347818374634},{"id":"https://openalex.org/C43270747","wikidata":"https://www.wikidata.org/wiki/Q898610","display_name":"Reflux","level":3,"score":0.27249258756637573},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000367","descriptor_name":"Age Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005764","descriptor_name":"Gastroesophageal Reflux","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D005764","descriptor_name":"Gastroesophageal Reflux","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005764","descriptor_name":"Gastroesophageal Reflux","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008365","descriptor_name":"Manometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011312","descriptor_name":"Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015154","descriptor_name":"Esophageal Motility Disorders","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D015154","descriptor_name":"Esophageal Motility Disorders","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D015154","descriptor_name":"Esophageal Motility Disorders","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D049630","descriptor_name":"Esophageal Sphincter, Lower","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.arcmed.2011.02.003","doi":"https://doi.org/10.1016/j.arcmed.2011.02.003","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.arcmed.2011.02.003","pdf_url":null,"source":{"id":"https://openalex.org/S157833918","display_name":"Archives of Medical Research","issn_l":"0066-6769","issn":["0066-6769","0188-0128","0188-4409","1873-5487"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of Medical Research","raw_type":"journal-article"},{"id":"pmid:21565622","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21565622","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of medical research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W15645319","https://openalex.org/W61767037","https://openalex.org/W150135378","https://openalex.org/W165295037","https://openalex.org/W646741695","https://openalex.org/W1511660984","https://openalex.org/W1552977327","https://openalex.org/W1964064196","https://openalex.org/W1978560184","https://openalex.org/W1990630738","https://openalex.org/W1994490818","https://openalex.org/W2008373894","https://openalex.org/W2012050771","https://openalex.org/W2013455679","https://openalex.org/W2024337521","https://openalex.org/W2025737230","https://openalex.org/W2037202496","https://openalex.org/W2038812225","https://openalex.org/W2047822215","https://openalex.org/W2050638435","https://openalex.org/W2063280682","https://openalex.org/W2079887058","https://openalex.org/W2096990357","https://openalex.org/W2112181175","https://openalex.org/W2121952437","https://openalex.org/W2127395151","https://openalex.org/W2130721477","https://openalex.org/W2142317898","https://openalex.org/W2158337509","https://openalex.org/W2178833848","https://openalex.org/W2416330590","https://openalex.org/W4230136235","https://openalex.org/W4240221116","https://openalex.org/W4300474639","https://openalex.org/W6606646392"],"related_works":["https://openalex.org/W2158337509","https://openalex.org/W2032627757","https://openalex.org/W2172219879","https://openalex.org/W2051348554","https://openalex.org/W2979264257","https://openalex.org/W1986981597","https://openalex.org/W15645319","https://openalex.org/W2766245781","https://openalex.org/W3030412850","https://openalex.org/W2009962127"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2016-06-24T00:00:00"}
