{"id":"https://openalex.org/W2084865893","doi":"https://doi.org/10.1016/0008-8749(92)90254-m","title":"Comparison of the capacity of murine and human class I MHC molecules to stimulate T cell activation","display_name":"Comparison of the capacity of murine and human class I MHC molecules to stimulate T cell activation","publication_year":1992,"publication_date":"1992-10-01","ids":{"openalex":"https://openalex.org/W2084865893","doi":"https://doi.org/10.1016/0008-8749(92)90254-m","mag":"2084865893","pmid":"https://pubmed.ncbi.nlm.nih.gov/1394450"},"language":"en","primary_location":{"id":"doi:10.1016/0008-8749(92)90254-m","doi":"https://doi.org/10.1016/0008-8749(92)90254-m","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0008-8749(92)90254-m","pdf_url":null,"source":{"id":"https://openalex.org/S193466101","display_name":"Cellular Immunology","issn_l":"0008-8749","issn":["0008-8749","1090-2163"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular Immunology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5107415745","display_name":"Hanan Gur","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hanan Gur","raw_affiliation_strings":["Harold C. Simmons Arthritis Research Center, Department of Internal Medicine, University of Texas, Southwestern Medical Center, Dallas 75235"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Harold C. Simmons Arthritis Research Center, Department of Internal Medicine, University of Texas, Southwestern Medical Center, Dallas 75235","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069977506","display_name":"Mary C. Wacholtz","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mary C. Wacholtz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021337832","display_name":"Wen\u2010Rong Lie","orcid":"https://orcid.org/0000-0001-9014-1680","observed_orcids":["https://orcid.org/0000-0001-9014-1680"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wen-Rong Lie","raw_affiliation_strings":["Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63110, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63110, U.S.A","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043874873","display_name":"Peter E. Lipsky","orcid":"https://orcid.org/0000-0002-9287-1676","observed_orcids":["https://orcid.org/0000-0002-9287-1676"]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peter E. Lipsky","raw_affiliation_strings":["Harold C. Simmons Arthritis Research Center, Division of Rheumatic Diseases, Department of Internal Medicine, The University of Texas Southwestern Medical Center at Dallas, 5323 Harry Mines Boulevard, Dallas, Texas 75235 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Harold C. Simmons Arthritis Research Center, Division of Rheumatic Diseases, Department of Internal Medicine, The University of Texas Southwestern Medical Center at Dallas, 5323 Harry Mines Boulevard, Dallas, Texas 75235 U.S.A","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046173372","display_name":"Thomas D. Geppert","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Thomas D. Geppert","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3550,"currency":"USD","value_usd":3550},"apc_paid":null,"fwci":0.1611,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.46399749,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"144","issue":"2","first_page":"392","last_page":"406"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9775000214576721,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9775000214576721,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.01360000018030405,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mhc-class-i","display_name":"MHC class I","score":0.9409999847412109},{"id":"https://openalex.org/keywords/t-cell-activation","display_name":"T cell activation","score":0.9430000185966492},{"id":"https://openalex.org/keywords/signal-transduction","display_name":"signal transduction","score":0.8999999761581421},{"id":"https://openalex.org/keywords/hla-b27","display_name":"HLA-B27","score":0.7889999747276306},{"id":"https://openalex.org/keywords/intracellular-calcium","display_name":"intracellular calcium","score":0.7739999890327454},{"id":"https://openalex.org/keywords/t-cell-proliferation","display_name":"T cell proliferation","score":0.8529999852180481},{"id":"https://openalex.org/keywords/interleukin-2","display_name":"interleukin-2","score":0.7730000019073486},{"id":"https://openalex.org/keywords/pma","display_name":"PMA","score":0.8029999732971191},{"id":"https://openalex.org/keywords/costimulation","display_name":"costimulation","score":0.6579999923706055},{"id":"https://openalex.org/keywords/jurkat-cells","display_name":"Jurkat cells","score":0.7329999804496765}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7074084281921387},{"id":"https://openalex.org/C170627219","wikidata":"https://www.wikidata.org/wiki/Q13218497","display_name":"MHC class I","level":4,"score":0.681708574295044},{"id":"https://openalex.org/C207936829","wikidata":"https://www.wikidata.org/wiki/Q423163","display_name":"Major histocompatibility complex","level":3,"score":0.5904801487922668},{"id":"https://openalex.org/C179464577","wikidata":"https://www.wikidata.org/wiki/Q1632589","display_name":"Jurkat cells","level":4,"score":0.5691168308258057},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.5665808916091919},{"id":"https://openalex.org/C37386791","wikidata":"https://www.wikidata.org/wiki/Q2248081","display_name":"CD1","level":5,"score":0.5530809760093689},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5517621636390686},{"id":"https://openalex.org/C197695756","wikidata":"https://www.wikidata.org/wiki/Q1750372","display_name":"MHC restriction","level":5,"score":0.5245404839515686},{"id":"https://openalex.org/C2778814158","wikidata":"https://www.wikidata.org/wiki/Q959350","display_name":"MHC class II","level":4,"score":0.5052102208137512},{"id":"https://openalex.org/C119997001","wikidata":"https://www.wikidata.org/wiki/Q21113110","display_name":"CD74","level":5,"score":0.4868027865886688},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4682033658027649},{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.4450758397579193},{"id":"https://openalex.org/C54009773","wikidata":"https://www.wikidata.org/wiki/Q1429031","display_name":"Transfection","level":3,"score":0.4198567867279053},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.3899945318698883},{"id":"https://openalex.org/C67662055","wikidata":"https://www.wikidata.org/wiki/Q1047791","display_name":"Antigen-presenting cell","level":4,"score":0.2748048007488251},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.2548261284828186},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.24382877349853516},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.22735458612442017},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.14400547742843628},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.099315345287323},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.08577191829681396}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007376","descriptor_name":"Interleukin-2","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D008213","descriptor_name":"Lymphocyte Activation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D013755","descriptor_name":"Tetradecanoylphorbol Acetate","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D014162","descriptor_name":"Transfection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015395","descriptor_name":"Histocompatibility Antigens Class I","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0008-8749(92)90254-m","doi":"https://doi.org/10.1016/0008-8749(92)90254-m","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0008-8749(92)90254-m","pdf_url":null,"source":{"id":"https://openalex.org/S193466101","display_name":"Cellular Immunology","issn_l":"0008-8749","issn":["0008-8749","1090-2163"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular Immunology","raw_type":"journal-article"},{"id":"pmid:1394450","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1394450","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular immunology","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.5683000087738037}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1203208806","display_name":null,"funder_award_id":"AR-09989","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G5226126809","display_name":null,"funder_award_id":"AR-39169","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G6576976033","display_name":"SCOR IN RHEUMATOID ARTHRITIS","funder_award_id":"5p50ar039169-10","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8021232652","display_name":"IMMUNOLOGIC ASPECTS OF THE RHEUMATIC DISEASES","funder_award_id":"5p01ar009989-28","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337362","display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","ror":"https://ror.org/006zn3t30"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W1481539413","https://openalex.org/W1496389399","https://openalex.org/W1508956796","https://openalex.org/W1529159354","https://openalex.org/W1537923608","https://openalex.org/W1541707305","https://openalex.org/W1544637604","https://openalex.org/W1546326396","https://openalex.org/W1547328769","https://openalex.org/W1556891980","https://openalex.org/W1561252894","https://openalex.org/W1562079541","https://openalex.org/W1568866111","https://openalex.org/W1581716240","https://openalex.org/W1593396442","https://openalex.org/W1594002372","https://openalex.org/W1985402375","https://openalex.org/W1986070284","https://openalex.org/W2000631927","https://openalex.org/W2013732768","https://openalex.org/W2024441858","https://openalex.org/W2026923875","https://openalex.org/W2037327557","https://openalex.org/W2052869090","https://openalex.org/W2053730131","https://openalex.org/W2055271950","https://openalex.org/W2076370934","https://openalex.org/W2077863721","https://openalex.org/W2108777421","https://openalex.org/W2113746427","https://openalex.org/W2127817780","https://openalex.org/W2161959951","https://openalex.org/W2170924043","https://openalex.org/W2414221147"],"related_works":["https://openalex.org/W1593396442","https://openalex.org/W2050590254","https://openalex.org/W2044012243","https://openalex.org/W7100507469","https://openalex.org/W2075823594","https://openalex.org/W1547328769","https://openalex.org/W2161959951","https://openalex.org/W28750489","https://openalex.org/W1582992689","https://openalex.org/W1537923608"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}