{"id":"https://openalex.org/W2084685705","doi":"https://doi.org/10.1016/j.jim.2008.02.006","title":"Antigen presentation of detergent-free glutamate decarboxylase (GAD65) is affected by human serum albumin as carrier protein","display_name":"Antigen presentation of detergent-free glutamate decarboxylase (GAD65) is affected by human serum albumin as carrier protein","publication_year":2008,"publication_date":"2008-03-10","ids":{"openalex":"https://openalex.org/W2084685705","doi":"https://doi.org/10.1016/j.jim.2008.02.006","mag":"2084685705","pmid":"https://pubmed.ncbi.nlm.nih.gov/18353353","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2442559"},"language":"en","primary_location":{"id":"doi:10.1016/j.jim.2008.02.006","doi":"https://doi.org/10.1016/j.jim.2008.02.006","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jim.2008.02.006","pdf_url":null,"source":{"id":"https://openalex.org/S201669150","display_name":"Journal of Immunological Methods","issn_l":"0022-1759","issn":["0022-1759","1872-7905"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Immunological Methods","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/articles/PMC2442559","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004953230","display_name":"Jordan Steed","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jordan Steed","raw_affiliation_strings":["Robert H. Williams Laboratory, Department of Medicine, University of Washington, Health Sciences Building K-165, 1959 Pacific Avenue NE, Seattle, WA 98195-3771, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Robert H. Williams Laboratory, Department of Medicine, University of Washington, Health Sciences Building K-165, 1959 Pacific Avenue NE, Seattle, WA 98195-3771, USA","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034609462","display_name":"Lisa K.\ufeff Gilliam","orcid":"https://orcid.org/0000-0001-7054-1409","observed_orcids":["https://orcid.org/0000-0001-7054-1409"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lisa K. Gilliam","raw_affiliation_strings":["Robert H. Williams Laboratory, Department of Medicine, University of Washington, Health Sciences Building K-165, 1959 Pacific Avenue NE, Seattle, WA 98195-3771, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Robert H. Williams Laboratory, Department of Medicine, University of Washington, Health Sciences Building K-165, 1959 Pacific Avenue NE, Seattle, WA 98195-3771, USA","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070191665","display_name":"Robert Adam Harris","orcid":"https://orcid.org/0000-0003-4990-509X","observed_orcids":["https://orcid.org/0000-0003-4990-509X"]},"institutions":[{"id":"https://openalex.org/I1335113835","display_name":"Karolinska University Hospital","ror":"https://ror.org/00m8d6786","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I1335113835"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Robert A. Harris","raw_affiliation_strings":["Applied Immunology, Center for Molecular Medicine, Karolinska Hospital, SE-171 76 Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Applied Immunology, Center for Molecular Medicine, Karolinska Hospital, SE-171 76 Stockholm, Sweden","institution_ids":["https://openalex.org/I1335113835"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008841181","display_name":"\u00c5ke Lernmark","orcid":"https://orcid.org/0000-0003-1735-0499","observed_orcids":["https://orcid.org/0000-0003-1735-0499"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"\u00c5ke Lernmark","raw_affiliation_strings":["Robert H. Williams Laboratory, Department of Medicine, University of Washington, Health Sciences Building K-165, 1959 Pacific Avenue NE, Seattle, WA 98195-3771, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Robert H. Williams Laboratory, Department of Medicine, University of Washington, Health Sciences Building K-165, 1959 Pacific Avenue NE, Seattle, WA 98195-3771, USA","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036401896","display_name":"Christiane S. Hampe","orcid":"https://orcid.org/0000-0001-9111-6671","observed_orcids":["https://orcid.org/0000-0001-9111-6671"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Christiane S. Hampe","raw_affiliation_strings":["Robert H. Williams Laboratory, Department of Medicine, University of Washington, Health Sciences Building K-165, 1959 Pacific Avenue NE, Seattle, WA 98195-3771, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Robert H. Williams Laboratory, Department of Medicine, University of Washington, Health Sciences Building K-165, 1959 Pacific Avenue NE, Seattle, WA 98195-3771, USA","institution_ids":["https://openalex.org/I201448701"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5036401896"],"corresponding_institution_ids":["https://openalex.org/I201448701"],"apc_list":{"value":2970,"currency":"USD","value_usd":2970},"apc_paid":null,"fwci":0.5703,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.70182812,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"334","issue":"1-2","first_page":"114","last_page":"121"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11171","display_name":"Diabetes and associated disorders","score":0.9653000235557556,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11171","display_name":"Diabetes and associated disorders","score":0.9653000235557556,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.01899999938905239,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.012199999764561653,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glutamate-decarboxylase-65","display_name":"glutamate decarboxylase 65","score":0.9100000262260437},{"id":"https://openalex.org/keywords/gad65","display_name":"GAD65","score":0.9279999732971191},{"id":"https://openalex.org/keywords/antigen-presentation","display_name":"antigen presentation","score":0.7559999823570251},{"id":"https://openalex.org/keywords/human-serum-albumin","display_name":"human serum albumin","score":0.9810000061988831},{"id":"https://openalex.org/keywords/type-1-diabetes","display_name":"type 1 diabetes","score":0.7459999918937683},{"id":"https://openalex.org/keywords/autoantigens","display_name":"autoantigens","score":0.699999988079071},{"id":"https://openalex.org/keywords/hla-drb1-04-01","display_name":"HLA-DRB1*0401","score":0.8970000147819519},{"id":"https://openalex.org/keywords/epitope-specificity","display_name":"epitope specificity","score":0.5979999899864197},{"id":"https://openalex.org/keywords/protein-solubilization","display_name":"protein solubilization","score":0.7179999947547913}],"concepts":[{"id":"https://openalex.org/C195616568","wikidata":"https://www.wikidata.org/wiki/Q128711","display_name":"Epitope","level":3,"score":0.9105924367904663},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.6376092433929443},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5130059123039246},{"id":"https://openalex.org/C2778597219","wikidata":"https://www.wikidata.org/wiki/Q11721976","display_name":"Human serum albumin","level":2,"score":0.4941242039203644},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.46090826392173767},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.45179060101509094},{"id":"https://openalex.org/C83464605","wikidata":"https://www.wikidata.org/wiki/Q575296","display_name":"Antigen presentation","level":4,"score":0.4472259283065796},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.4403132200241089},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.43843555450439453},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3831619918346405},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.25667059421539307},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2010192573070526},{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.057864099740982056}],"mesh":[{"descriptor_ui":"D001402","descriptor_name":"B-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D001402","descriptor_name":"B-Lymphocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005968","descriptor_name":"Glutamate Decarboxylase","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D005968","descriptor_name":"Glutamate Decarboxylase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006825","descriptor_name":"Hybridomas","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006825","descriptor_name":"Hybridomas","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007376","descriptor_name":"Interleukin-2","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D007376","descriptor_name":"Interleukin-2","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D011869","descriptor_name":"Radioligand Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012709","descriptor_name":"Serum Albumin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017951","descriptor_name":"Antigen Presentation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1016/j.jim.2008.02.006","doi":"https://doi.org/10.1016/j.jim.2008.02.006","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jim.2008.02.006","pdf_url":null,"source":{"id":"https://openalex.org/S201669150","display_name":"Journal of Immunological Methods","issn_l":"0022-1759","issn":["0022-1759","1872-7905"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Immunological Methods","raw_type":"journal-article"},{"id":"pmid:18353353","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18353353","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of immunological methods","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:1438972","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC2442559","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:2442559","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2442559","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Immunol Methods","raw_type":"Text"},{"id":"pmh:oai:lup.lub.lu.se:160c60ef-53ab-4e72-a6a0-266d6e7139a8","doi":null,"is_oa":false,"landing_page_url":"https://lup.lub.lu.se/record/160c60ef-53ab-4e72-a6a0-266d6e7139a8","pdf_url":null,"source":{"id":"https://openalex.org/S4306400536","display_name":"Lund University Publications (Lund University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I187531555","host_organization_name":"Lund University","host_organization_lineage":["https://openalex.org/I187531555"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Immunological Methods; 334(1-2), pp 114-121 (2008)","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:1438972","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC2442559","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2945543755","display_name":null,"funder_award_id":"DK55004","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G411541712","display_name":null,"funder_award_id":"DK-26190","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G4764177642","display_name":"Immunogenetics of Human Diabetes","funder_award_id":"P01DK053004","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G6216217890","display_name":"Islet Cell Membrane Antibodies in Diabetes","funder_award_id":"R01DK026190","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G781778653","display_name":"MECHANISMS OF PEPTIDE AND PROTEIN RECOGNITION, ASSEMBLY, FUNCTION","funder_award_id":"1z01dk055004-18","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320306089","display_name":"American Diabetes Association","ror":"https://ror.org/04f6cgz95"},{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W254393295","https://openalex.org/W1264463670","https://openalex.org/W1546683674","https://openalex.org/W1982544710","https://openalex.org/W1983520891","https://openalex.org/W1984037402","https://openalex.org/W2009596665","https://openalex.org/W2011118886","https://openalex.org/W2013943197","https://openalex.org/W2017654147","https://openalex.org/W2041412815","https://openalex.org/W2043747248","https://openalex.org/W2045385822","https://openalex.org/W2059144476","https://openalex.org/W2065342518","https://openalex.org/W2071472322","https://openalex.org/W2074885718","https://openalex.org/W2087849403","https://openalex.org/W2091075527","https://openalex.org/W2091765481","https://openalex.org/W2096041075","https://openalex.org/W2109997219","https://openalex.org/W2117055080","https://openalex.org/W2117975185","https://openalex.org/W2121154661","https://openalex.org/W2122855951","https://openalex.org/W2129551653","https://openalex.org/W2130138869","https://openalex.org/W2130697926","https://openalex.org/W2134318157","https://openalex.org/W2142627742","https://openalex.org/W2161576959","https://openalex.org/W2167845501","https://openalex.org/W2419509150","https://openalex.org/W4241035409","https://openalex.org/W6609530264","https://openalex.org/W6717580336"],"related_works":["https://openalex.org/W2313755486","https://openalex.org/W2121154661","https://openalex.org/W1986753195","https://openalex.org/W2085690625","https://openalex.org/W2096249455","https://openalex.org/W2130138869","https://openalex.org/W2068987483","https://openalex.org/W156201922","https://openalex.org/W2135525868","https://openalex.org/W2022878852"],"abstract_inverted_index":null,"counts_by_year":[{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}