{"id":"https://openalex.org/W2084639134","doi":"https://doi.org/10.1097/00002030-200310170-00006","title":"Phase I/II trial of intravenous recombinant interleukin-2 in HIV-infected children","display_name":"Phase I/II trial of intravenous recombinant interleukin-2 in HIV-infected children","publication_year":2003,"publication_date":"2003-10-01","ids":{"openalex":"https://openalex.org/W2084639134","doi":"https://doi.org/10.1097/00002030-200310170-00006","mag":"2084639134","pmid":"https://pubmed.ncbi.nlm.nih.gov/14523275"},"language":"en","primary_location":{"id":"doi:10.1097/00002030-200310170-00006","doi":"https://doi.org/10.1097/00002030-200310170-00006","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00002030-200310170-00006","pdf_url":null,"source":{"id":"https://openalex.org/S20605092","display_name":"AIDS","issn_l":"0269-9370","issn":["0269-9370","1473-5571"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIDS","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060651306","display_name":"Stuart E. Starr","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1335321130","display_name":"Children's Hospital of Philadelphia","ror":"https://ror.org/01z7r7q48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1335321130"]},{"id":"https://openalex.org/I2801202167","display_name":"MemorialCare Long Beach Medical Center","ror":"https://ror.org/021kgjd57","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801202167","https://openalex.org/I4210125374"]},{"id":"https://openalex.org/I4210111322","display_name":"Long Beach Medical Center","ror":"https://ror.org/02rt3gt49","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210111322","https://openalex.org/I4210125374"]},{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]},{"id":"https://openalex.org/I61515104","display_name":"University of Florida Health Science Center","ror":"https://ror.org/0419bgt07","country_code":"US","type":"education","lineage":["https://openalex.org/I61515104"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stuart E Starr","raw_affiliation_strings":["Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, USA","From the Childen's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, aUniversity of Colorado Health Sciences Center, Denver, Colorado, bStatistical and Data Analysis Center, Frontier Science and Technology Research Foundation, Inc., Brookline, Massachusetts, cColumbia University College of Physicians and Surgeons, New York, New York, dLong Beach Memorial Medical Center, Long Beach, California, eUniversity of Florida Health Science Center/Jacksonville, Jacksonville, Florida, USA. \u2020This author is deceased. *See Appendix","Note: This study was supported by the Pediatric AIDS Clinical Trials Group of the National Institute of Allergy and Infectious Diseases, the Pediatric/Perinatal HIV Clinical Trials Network of the National Institute of Child Health and Human Development, by General Clinical Research Centers funded by the National Center for Research Resources, and by Chiron Corporation","Received: 4 July 2002","accepted: 15 April 2003","revised: 7 October 2002"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, USA","institution_ids":["https://openalex.org/I1335321130","https://openalex.org/I79576946"]},{"raw_affiliation_string":"From the Childen's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, aUniversity of Colorado Health Sciences Center, Denver, Colorado, bStatistical and Data Analysis Center, Frontier Science and Technology Research Foundation, Inc., Brookline, Massachusetts, cColumbia University College of Physicians and Surgeons, New York, New York, dLong Beach Memorial Medical Center, Long Beach, California, eUniversity of Florida Health Science Center/Jacksonville, Jacksonville, Florida, USA. \u2020This author is deceased. *See Appendix","institution_ids":["https://openalex.org/I1335321130","https://openalex.org/I2801202167","https://openalex.org/I4210111322","https://openalex.org/I61515104","https://openalex.org/I79576946"]},{"raw_affiliation_string":"Note: This study was supported by the Pediatric AIDS Clinical Trials Group of the National Institute of Allergy and Infectious Diseases, the Pediatric/Perinatal HIV Clinical Trials Network of the National Institute of Child Health and Human Development, by General Clinical Research Centers funded by the National Center for Research Resources, and by Chiron Corporation","institution_ids":["https://openalex.org/I4210134534"]},{"raw_affiliation_string":"Received: 4 July 2002","institution_ids":[]},{"raw_affiliation_string":"accepted: 15 April 2003","institution_ids":[]},{"raw_affiliation_string":"revised: 7 October 2002","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010772046","display_name":"Elizabeth J. McFarland","orcid":"https://orcid.org/0000-0003-0653-8955","observed_orcids":["https://orcid.org/0000-0003-0653-8955"]},"institutions":[{"id":"https://openalex.org/I1335321130","display_name":"Children's Hospital of Philadelphia","ror":"https://ror.org/01z7r7q48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1335321130"]},{"id":"https://openalex.org/I2801202167","display_name":"MemorialCare Long Beach Medical Center","ror":"https://ror.org/021kgjd57","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801202167","https://openalex.org/I4210125374"]},{"id":"https://openalex.org/I4210111322","display_name":"Long Beach Medical Center","ror":"https://ror.org/02rt3gt49","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210111322","https://openalex.org/I4210125374"]},{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]},{"id":"https://openalex.org/I61515104","display_name":"University of Florida Health Science Center","ror":"https://ror.org/0419bgt07","country_code":"US","type":"education","lineage":["https://openalex.org/I61515104"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]},{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Elizabeth J McFarland","raw_affiliation_strings":["Note: This study was supported by the Pediatric AIDS Clinical Trials Group of the National Institute of Allergy and Infectious Diseases, the Pediatric/Perinatal HIV Clinical Trials Network of the National Institute of Child Health and Human Development, by General Clinical Research Centers funded by the National Center for Research Resources, and by Chiron Corporation","to E. J. McFarland, Pediatric Infectious Diseases, University of Colorado Health Sciences Center, Box C-227, 4200 East Ninth Avenue, Denver, CO 80262, USA","From the Childen's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, aUniversity of Colorado Health Sciences Center, Denver, Colorado, bStatistical and Data Analysis Center, Frontier Science and Technology Research Foundation, Inc., Brookline, Massachusetts, cColumbia University College of Physicians and Surgeons, New York, New York, dLong Beach Memorial Medical Center, Long Beach, California, eUniversity of Florida Health Science Center/Jacksonville, Jacksonville, Florida, USA. \u2020This author is deceased. *See Appendix","Received: 4 July 2002","accepted: 15 April 2003","revised: 7 October 2002"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Note: This study was supported by the Pediatric AIDS Clinical Trials Group of the National Institute of Allergy and Infectious Diseases, the Pediatric/Perinatal HIV Clinical Trials Network of the National Institute of Child Health and Human Development, by General Clinical Research Centers funded by the National Center for Research Resources, and by Chiron Corporation","institution_ids":["https://openalex.org/I4210134534"]},{"raw_affiliation_string":"to E. J. McFarland, Pediatric Infectious Diseases, University of Colorado Health Sciences Center, Box C-227, 4200 East Ninth Avenue, Denver, CO 80262, USA","institution_ids":["https://openalex.org/I921990950"]},{"raw_affiliation_string":"From the Childen's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, aUniversity of Colorado Health Sciences Center, Denver, Colorado, bStatistical and Data Analysis Center, Frontier Science and Technology Research Foundation, Inc., Brookline, Massachusetts, cColumbia University College of Physicians and Surgeons, New York, New York, dLong Beach Memorial Medical Center, Long Beach, California, eUniversity of Florida Health Science Center/Jacksonville, Jacksonville, Florida, USA. \u2020This author is deceased. *See Appendix","institution_ids":["https://openalex.org/I1335321130","https://openalex.org/I2801202167","https://openalex.org/I4210111322","https://openalex.org/I61515104","https://openalex.org/I79576946"]},{"raw_affiliation_string":"Received: 4 July 2002","institution_ids":[]},{"raw_affiliation_string":"accepted: 15 April 2003","institution_ids":[]},{"raw_affiliation_string":"revised: 7 October 2002","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026928748","display_name":"Petronella Muresan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1335321130","display_name":"Children's Hospital of Philadelphia","ror":"https://ror.org/01z7r7q48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1335321130"]},{"id":"https://openalex.org/I2801202167","display_name":"MemorialCare Long Beach Medical Center","ror":"https://ror.org/021kgjd57","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801202167","https://openalex.org/I4210125374"]},{"id":"https://openalex.org/I4210111322","display_name":"Long Beach Medical Center","ror":"https://ror.org/02rt3gt49","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210111322","https://openalex.org/I4210125374"]},{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]},{"id":"https://openalex.org/I61515104","display_name":"University of Florida Health Science Center","ror":"https://ror.org/0419bgt07","country_code":"US","type":"education","lineage":["https://openalex.org/I61515104"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]},{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Petronella Muresan","raw_affiliation_strings":["Note: This study was supported by the Pediatric AIDS Clinical Trials Group of the National Institute of Allergy and Infectious Diseases, the Pediatric/Perinatal HIV Clinical Trials Network of the National Institute of Child Health and Human Development, by General Clinical Research Centers funded by the National Center for Research Resources, and by Chiron Corporation","to E. J. McFarland, Pediatric Infectious Diseases, University of Colorado Health Sciences Center, Box C-227, 4200 East Ninth Avenue, Denver, CO 80262, USA","From the Childen's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, aUniversity of Colorado Health Sciences Center, Denver, Colorado, bStatistical and Data Analysis Center, Frontier Science and Technology Research Foundation, Inc., Brookline, Massachusetts, cColumbia University College of Physicians and Surgeons, New York, New York, dLong Beach Memorial Medical Center, Long Beach, California, eUniversity of Florida Health Science Center/Jacksonville, Jacksonville, Florida, USA. \u2020This author is deceased. *See Appendix","Received: 4 July 2002","accepted: 15 April 2003","revised: 7 October 2002"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Note: This study was supported by the Pediatric AIDS Clinical Trials Group of the National Institute of Allergy and Infectious Diseases, the Pediatric/Perinatal HIV Clinical Trials Network of the National Institute of Child Health and Human Development, by General Clinical Research Centers funded by the National Center for Research Resources, and by Chiron Corporation","institution_ids":["https://openalex.org/I4210134534"]},{"raw_affiliation_string":"to E. J. McFarland, Pediatric Infectious Diseases, University of Colorado Health Sciences Center, Box C-227, 4200 East Ninth Avenue, Denver, CO 80262, USA","institution_ids":["https://openalex.org/I921990950"]},{"raw_affiliation_string":"From the Childen's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, aUniversity of Colorado Health Sciences Center, Denver, Colorado, bStatistical and Data Analysis Center, Frontier Science and Technology Research Foundation, Inc., Brookline, Massachusetts, cColumbia University College of Physicians and Surgeons, New York, New York, dLong Beach Memorial Medical Center, Long Beach, California, eUniversity of Florida Health Science Center/Jacksonville, Jacksonville, Florida, USA. \u2020This author is deceased. *See Appendix","institution_ids":["https://openalex.org/I1335321130","https://openalex.org/I2801202167","https://openalex.org/I4210111322","https://openalex.org/I61515104","https://openalex.org/I79576946"]},{"raw_affiliation_string":"Received: 4 July 2002","institution_ids":[]},{"raw_affiliation_string":"accepted: 15 April 2003","institution_ids":[]},{"raw_affiliation_string":"revised: 7 October 2002","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109243130","display_name":"Terence Fenton","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1335321130","display_name":"Children's Hospital of Philadelphia","ror":"https://ror.org/01z7r7q48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1335321130"]},{"id":"https://openalex.org/I2801202167","display_name":"MemorialCare Long Beach Medical Center","ror":"https://ror.org/021kgjd57","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801202167","https://openalex.org/I4210125374"]},{"id":"https://openalex.org/I4210111322","display_name":"Long Beach Medical Center","ror":"https://ror.org/02rt3gt49","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210111322","https://openalex.org/I4210125374"]},{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]},{"id":"https://openalex.org/I61515104","display_name":"University of Florida Health Science Center","ror":"https://ror.org/0419bgt07","country_code":"US","type":"education","lineage":["https://openalex.org/I61515104"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]},{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Terence Fenton","raw_affiliation_strings":["Note: This study was supported by the Pediatric AIDS Clinical Trials Group of the National Institute of Allergy and Infectious Diseases, the Pediatric/Perinatal HIV Clinical Trials Network of the National Institute of Child Health and Human Development, by General Clinical Research Centers funded by the National Center for Research Resources, and by Chiron Corporation","to E. J. McFarland, Pediatric Infectious Diseases, University of Colorado Health Sciences Center, Box C-227, 4200 East Ninth Avenue, Denver, CO 80262, USA","From the Childen's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, aUniversity of Colorado Health Sciences Center, Denver, Colorado, bStatistical and Data Analysis Center, Frontier Science and Technology Research Foundation, Inc., Brookline, Massachusetts, cColumbia University College of Physicians and Surgeons, New York, New York, dLong Beach Memorial Medical Center, Long Beach, California, eUniversity of Florida Health Science Center/Jacksonville, Jacksonville, Florida, USA. \u2020This author is deceased. *See Appendix","Received: 4 July 2002","accepted: 15 April 2003","revised: 7 October 2002"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Note: This study was supported by the Pediatric AIDS Clinical Trials Group of the National Institute of Allergy and Infectious Diseases, the Pediatric/Perinatal HIV Clinical Trials Network of the National Institute of Child Health and Human Development, by General Clinical Research Centers funded by the National Center for Research Resources, and by Chiron Corporation","institution_ids":["https://openalex.org/I4210134534"]},{"raw_affiliation_string":"to E. J. McFarland, Pediatric Infectious Diseases, University of Colorado Health Sciences Center, Box C-227, 4200 East Ninth Avenue, Denver, CO 80262, USA","institution_ids":["https://openalex.org/I921990950"]},{"raw_affiliation_string":"From the Childen's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, aUniversity of Colorado Health Sciences Center, Denver, Colorado, bStatistical and Data Analysis Center, Frontier Science and Technology Research Foundation, Inc., Brookline, Massachusetts, cColumbia University College of Physicians and Surgeons, New York, New York, dLong Beach Memorial Medical Center, Long Beach, California, eUniversity of Florida Health Science Center/Jacksonville, Jacksonville, Florida, USA. \u2020This author is deceased. *See Appendix","institution_ids":["https://openalex.org/I1335321130","https://openalex.org/I2801202167","https://openalex.org/I4210111322","https://openalex.org/I61515104","https://openalex.org/I79576946"]},{"raw_affiliation_string":"Received: 4 July 2002","institution_ids":[]},{"raw_affiliation_string":"accepted: 15 April 2003","institution_ids":[]},{"raw_affiliation_string":"revised: 7 October 2002","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108408180","display_name":"Jane Pitt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1335321130","display_name":"Children's Hospital of Philadelphia","ror":"https://ror.org/01z7r7q48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1335321130"]},{"id":"https://openalex.org/I2801202167","display_name":"MemorialCare Long Beach Medical Center","ror":"https://ror.org/021kgjd57","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801202167","https://openalex.org/I4210125374"]},{"id":"https://openalex.org/I4210111322","display_name":"Long Beach Medical Center","ror":"https://ror.org/02rt3gt49","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210111322","https://openalex.org/I4210125374"]},{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]},{"id":"https://openalex.org/I61515104","display_name":"University of Florida Health Science Center","ror":"https://ror.org/0419bgt07","country_code":"US","type":"education","lineage":["https://openalex.org/I61515104"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]},{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jane Pitt","raw_affiliation_strings":["Note: This study was supported by the Pediatric AIDS Clinical Trials Group of the National Institute of Allergy and Infectious Diseases, the Pediatric/Perinatal HIV Clinical Trials Network of the National Institute of Child Health and Human Development, by General Clinical Research Centers funded by the National Center for Research Resources, and by Chiron Corporation","to E. J. McFarland, Pediatric Infectious Diseases, University of Colorado Health Sciences Center, Box C-227, 4200 East Ninth Avenue, Denver, CO 80262, USA","From the Childen's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, aUniversity of Colorado Health Sciences Center, Denver, Colorado, bStatistical and Data Analysis Center, Frontier Science and Technology Research Foundation, Inc., Brookline, Massachusetts, cColumbia University College of Physicians and Surgeons, New York, New York, dLong Beach Memorial Medical Center, Long Beach, California, eUniversity of Florida Health Science Center/Jacksonville, Jacksonville, Florida, USA. \u2020This author is deceased. *See Appendix","Received: 4 July 2002","accepted: 15 April 2003","revised: 7 October 2002"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Note: This study was supported by the Pediatric AIDS Clinical Trials Group of the National Institute of Allergy and Infectious Diseases, the Pediatric/Perinatal HIV Clinical Trials Network of the National Institute of Child Health and Human Development, by General Clinical Research Centers funded by the National Center for Research Resources, and by Chiron Corporation","institution_ids":["https://openalex.org/I4210134534"]},{"raw_affiliation_string":"to E. J. McFarland, Pediatric Infectious Diseases, University of Colorado Health Sciences Center, Box C-227, 4200 East Ninth Avenue, Denver, CO 80262, USA","institution_ids":["https://openalex.org/I921990950"]},{"raw_affiliation_string":"From the Childen's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, aUniversity of Colorado Health Sciences Center, Denver, Colorado, bStatistical and Data Analysis Center, Frontier Science and Technology Research Foundation, Inc., Brookline, Massachusetts, cColumbia University College of Physicians and Surgeons, New York, New York, dLong Beach Memorial Medical Center, Long Beach, California, eUniversity of Florida Health Science Center/Jacksonville, Jacksonville, Florida, USA. \u2020This author is deceased. *See Appendix","institution_ids":["https://openalex.org/I1335321130","https://openalex.org/I2801202167","https://openalex.org/I4210111322","https://openalex.org/I61515104","https://openalex.org/I79576946"]},{"raw_affiliation_string":"Received: 4 July 2002","institution_ids":[]},{"raw_affiliation_string":"accepted: 15 April 2003","institution_ids":[]},{"raw_affiliation_string":"revised: 7 October 2002","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037161551","display_name":"Steven D. Douglas","orcid":"https://orcid.org/0000-0002-3748-3603","observed_orcids":["https://orcid.org/0000-0002-3748-3603"]},"institutions":[{"id":"https://openalex.org/I1335321130","display_name":"Children's Hospital of Philadelphia","ror":"https://ror.org/01z7r7q48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1335321130"]},{"id":"https://openalex.org/I2801202167","display_name":"MemorialCare Long Beach Medical Center","ror":"https://ror.org/021kgjd57","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801202167","https://openalex.org/I4210125374"]},{"id":"https://openalex.org/I4210111322","display_name":"Long Beach Medical Center","ror":"https://ror.org/02rt3gt49","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210111322","https://openalex.org/I4210125374"]},{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]},{"id":"https://openalex.org/I61515104","display_name":"University of Florida Health Science Center","ror":"https://ror.org/0419bgt07","country_code":"US","type":"education","lineage":["https://openalex.org/I61515104"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]},{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven D Douglas","raw_affiliation_strings":["Note: This study was supported by the Pediatric AIDS Clinical Trials Group of the National Institute of Allergy and Infectious Diseases, the Pediatric/Perinatal HIV Clinical Trials Network of the National Institute of Child Health and Human Development, by General Clinical Research Centers funded by the National Center for Research Resources, and by Chiron Corporation","to E. J. McFarland, Pediatric Infectious Diseases, University of Colorado Health Sciences Center, Box C-227, 4200 East Ninth Avenue, Denver, CO 80262, USA","From the Childen's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, aUniversity of Colorado Health Sciences Center, Denver, Colorado, bStatistical and Data Analysis Center, Frontier Science and Technology Research Foundation, Inc., Brookline, Massachusetts, cColumbia University College of Physicians and Surgeons, New York, New York, dLong Beach Memorial Medical Center, Long Beach, California, eUniversity of Florida Health Science Center/Jacksonville, Jacksonville, Florida, USA. \u2020This author is deceased. *See Appendix","Received: 4 July 2002","accepted: 15 April 2003","revised: 7 October 2002"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Note: This study was supported by the Pediatric AIDS Clinical Trials Group of the National Institute of Allergy and Infectious Diseases, the Pediatric/Perinatal HIV Clinical Trials Network of the National Institute of Child Health and Human Development, by General Clinical Research Centers funded by the National Center for Research Resources, and by Chiron Corporation","institution_ids":["https://openalex.org/I4210134534"]},{"raw_affiliation_string":"to E. J. McFarland, Pediatric Infectious Diseases, University of Colorado Health Sciences Center, Box C-227, 4200 East Ninth Avenue, Denver, CO 80262, USA","institution_ids":["https://openalex.org/I921990950"]},{"raw_affiliation_string":"From the Childen's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, aUniversity of Colorado Health Sciences Center, Denver, Colorado, bStatistical and Data Analysis Center, Frontier Science and Technology Research Foundation, Inc., Brookline, Massachusetts, cColumbia University College of Physicians and Surgeons, New York, New York, dLong Beach Memorial Medical Center, Long Beach, California, eUniversity of Florida Health Science Center/Jacksonville, Jacksonville, Florida, USA. \u2020This author is deceased. *See Appendix","institution_ids":["https://openalex.org/I1335321130","https://openalex.org/I2801202167","https://openalex.org/I4210111322","https://openalex.org/I61515104","https://openalex.org/I79576946"]},{"raw_affiliation_string":"Received: 4 July 2002","institution_ids":[]},{"raw_affiliation_string":"accepted: 15 April 2003","institution_ids":[]},{"raw_affiliation_string":"revised: 7 October 2002","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065989725","display_name":"Audra Deveikis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1335321130","display_name":"Children's Hospital of Philadelphia","ror":"https://ror.org/01z7r7q48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1335321130"]},{"id":"https://openalex.org/I2801202167","display_name":"MemorialCare Long Beach Medical Center","ror":"https://ror.org/021kgjd57","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801202167","https://openalex.org/I4210125374"]},{"id":"https://openalex.org/I4210111322","display_name":"Long Beach Medical Center","ror":"https://ror.org/02rt3gt49","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210111322","https://openalex.org/I4210125374"]},{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]},{"id":"https://openalex.org/I61515104","display_name":"University of Florida Health Science Center","ror":"https://ror.org/0419bgt07","country_code":"US","type":"education","lineage":["https://openalex.org/I61515104"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]},{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Audra Deveikis","raw_affiliation_strings":["Note: This study was supported by the Pediatric AIDS Clinical Trials Group of the National Institute of Allergy and Infectious Diseases, the Pediatric/Perinatal HIV Clinical Trials Network of the National Institute of Child Health and Human Development, by General Clinical Research Centers funded by the National Center for Research Resources, and by Chiron Corporation","to E. J. McFarland, Pediatric Infectious Diseases, University of Colorado Health Sciences Center, Box C-227, 4200 East Ninth Avenue, Denver, CO 80262, USA","From the Childen's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, aUniversity of Colorado Health Sciences Center, Denver, Colorado, bStatistical and Data Analysis Center, Frontier Science and Technology Research Foundation, Inc., Brookline, Massachusetts, cColumbia University College of Physicians and Surgeons, New York, New York, dLong Beach Memorial Medical Center, Long Beach, California, eUniversity of Florida Health Science Center/Jacksonville, Jacksonville, Florida, USA. \u2020This author is deceased. *See Appendix","Received: 4 July 2002","accepted: 15 April 2003","revised: 7 October 2002"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Note: This study was supported by the Pediatric AIDS Clinical Trials Group of the National Institute of Allergy and Infectious Diseases, the Pediatric/Perinatal HIV Clinical Trials Network of the National Institute of Child Health and Human Development, by General Clinical Research Centers funded by the National Center for Research Resources, and by Chiron Corporation","institution_ids":["https://openalex.org/I4210134534"]},{"raw_affiliation_string":"to E. 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McFarland, Pediatric Infectious Diseases, University of Colorado Health Sciences Center, Box C-227, 4200 East Ninth Avenue, Denver, CO 80262, USA","institution_ids":["https://openalex.org/I921990950"]},{"raw_affiliation_string":"From the Childen's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, aUniversity of Colorado Health Sciences Center, Denver, Colorado, bStatistical and Data Analysis Center, Frontier Science and Technology Research Foundation, Inc., Brookline, Massachusetts, cColumbia University College of Physicians and Surgeons, New York, New York, dLong Beach Memorial Medical Center, Long Beach, California, eUniversity of Florida Health Science Center/Jacksonville, Jacksonville, Florida, USA. \u2020This author is deceased. *See Appendix","institution_ids":["https://openalex.org/I1335321130","https://openalex.org/I2801202167","https://openalex.org/I4210111322","https://openalex.org/I61515104","https://openalex.org/I79576946"]},{"raw_affiliation_string":"Received: 4 July 2002","institution_ids":[]},{"raw_affiliation_string":"accepted: 15 April 2003","institution_ids":[]},{"raw_affiliation_string":"revised: 7 October 2002","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051264386","display_name":"Myron J. 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J. McFarland, Pediatric Infectious Diseases, University of Colorado Health Sciences Center, Box C-227, 4200 East Ninth Avenue, Denver, CO 80262, USA","From the Childen's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, aUniversity of Colorado Health Sciences Center, Denver, Colorado, bStatistical and Data Analysis Center, Frontier Science and Technology Research Foundation, Inc., Brookline, Massachusetts, cColumbia University College of Physicians and Surgeons, New York, New York, dLong Beach Memorial Medical Center, Long Beach, California, eUniversity of Florida Health Science Center/Jacksonville, Jacksonville, Florida, USA. \u2020This author is deceased. *See Appendix","Received: 4 July 2002","accepted: 15 April 2003","revised: 7 October 2002"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Note: This study was supported by the Pediatric AIDS Clinical Trials Group of the National Institute of Allergy and Infectious Diseases, the Pediatric/Perinatal HIV Clinical Trials Network of the National Institute of Child Health and Human Development, by General Clinical Research Centers funded by the National Center for Research Resources, and by Chiron Corporation","institution_ids":["https://openalex.org/I4210134534"]},{"raw_affiliation_string":"to E. 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McFarland, Pediatric Infectious Diseases, University of Colorado Health Sciences Center, Box C-227, 4200 East Ninth Avenue, Denver, CO 80262, USA","institution_ids":["https://openalex.org/I921990950"]},{"raw_affiliation_string":"From the Childen's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, aUniversity of Colorado Health Sciences Center, Denver, Colorado, bStatistical and Data Analysis Center, Frontier Science and Technology Research Foundation, Inc., Brookline, Massachusetts, cColumbia University College of Physicians and Surgeons, New York, New York, dLong Beach Memorial Medical Center, Long Beach, California, eUniversity of Florida Health Science Center/Jacksonville, Jacksonville, Florida, USA. \u2020This author is deceased. *See Appendix","institution_ids":["https://openalex.org/I1335321130","https://openalex.org/I2801202167","https://openalex.org/I4210111322","https://openalex.org/I61515104","https://openalex.org/I79576946"]},{"raw_affiliation_string":"Received: 4 July 2002","institution_ids":[]},{"raw_affiliation_string":"accepted: 15 April 2003","institution_ids":[]},{"raw_affiliation_string":"revised: 7 October 2002","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5077436590","display_name":"Mobeen H. 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J. McFarland, Pediatric Infectious Diseases, University of Colorado Health Sciences Center, Box C-227, 4200 East Ninth Avenue, Denver, CO 80262, USA","From the Childen's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, aUniversity of Colorado Health Sciences Center, Denver, Colorado, bStatistical and Data Analysis Center, Frontier Science and Technology Research Foundation, Inc., Brookline, Massachusetts, cColumbia University College of Physicians and Surgeons, New York, New York, dLong Beach Memorial Medical Center, Long Beach, California, eUniversity of Florida Health Science Center/Jacksonville, Jacksonville, Florida, USA. \u2020This author is deceased. *See Appendix","Received: 4 July 2002","accepted: 15 April 2003","revised: 7 October 2002"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Note: This study was supported by the Pediatric AIDS Clinical Trials Group of the National Institute of Allergy and Infectious Diseases, the Pediatric/Perinatal HIV Clinical Trials Network of the National Institute of Child Health and Human Development, by General Clinical Research Centers funded by the National Center for Research Resources, and by Chiron Corporation","institution_ids":["https://openalex.org/I4210134534"]},{"raw_affiliation_string":"to E. 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