{"id":"https://openalex.org/W2084530981","doi":"https://doi.org/10.1159/000069121","title":"Air Travel-Associated Venous Thromboembolism","display_name":"Air Travel-Associated Venous Thromboembolism","publication_year":2003,"publication_date":"2003-01-01","ids":{"openalex":"https://openalex.org/W2084530981","doi":"https://doi.org/10.1159/000069121","mag":"2084530981","pmid":"https://pubmed.ncbi.nlm.nih.gov/12634460"},"language":"en","primary_location":{"id":"doi:10.1159/000069121","doi":"https://doi.org/10.1159/000069121","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000069121","pdf_url":null,"source":{"id":"https://openalex.org/S54128167","display_name":"Medical Principles and Practice","issn_l":"1011-7571","issn":["1011-7571","1423-0151"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Principles and Practice","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034121067","display_name":"Omer Iqbal","orcid":"https://orcid.org/0000-0002-0791-6957","observed_orcids":["https://orcid.org/0000-0002-0791-6957"]},"institutions":[{"id":"https://openalex.org/I1304196042","display_name":"Loyola University Medical Center","ror":"https://ror.org/05xcyt367","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1304196042","https://openalex.org/I1304269903"]},{"id":"https://openalex.org/I4210159390","display_name":"Loyola Medicine","ror":"https://ror.org/04azs9g49","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210159390"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Omer Iqbal","raw_affiliation_strings":["Department of Pathology, Loyola University Medical Center, Maywood, Ill 60153, USA. oiqbal@lumc.edu","Loyola University Medical Center, Maywood, Ill., and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Loyola University Medical Center, Maywood, Ill 60153, USA. oiqbal@lumc.edu","institution_ids":["https://openalex.org/I1304196042","https://openalex.org/I4210159390"]},{"raw_affiliation_string":"Loyola University Medical Center, Maywood, Ill., and","institution_ids":["https://openalex.org/I1304196042"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113758414","display_name":"Bo Ekl\u00f6f","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I117965899","display_name":"University of Hawai\u02bbi at M\u0101noa","ror":"https://ror.org/01wspgy28","country_code":"US","type":"education","lineage":["https://openalex.org/I117965899"]},{"id":"https://openalex.org/I1331384533","display_name":"University of Hawaii System","ror":"https://ror.org/03tzaeb71","country_code":"US","type":"education","lineage":["https://openalex.org/I1331384533"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bo Eklof","raw_affiliation_strings":["University of Hawaii, Honolulu, Hawaii, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Hawaii, Honolulu, Hawaii, USA","institution_ids":["https://openalex.org/I117965899","https://openalex.org/I1331384533"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087695849","display_name":"Mahmut T\u00f6b\u00fc","orcid":"https://orcid.org/0000-0001-5939-4989","observed_orcids":["https://orcid.org/0000-0001-5939-4989"]},"institutions":[{"id":"https://openalex.org/I1304196042","display_name":"Loyola University Medical Center","ror":"https://ror.org/05xcyt367","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1304196042","https://openalex.org/I1304269903"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mahmut Tobu","raw_affiliation_strings":["Loyola University Medical Center, Maywood, Ill., and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Loyola University Medical Center, Maywood, Ill., and","institution_ids":["https://openalex.org/I1304196042"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007859032","display_name":"Jawed Fareed","orcid":"https://orcid.org/0000-0003-3465-2499","observed_orcids":["https://orcid.org/0000-0003-3465-2499"]},"institutions":[{"id":"https://openalex.org/I1304196042","display_name":"Loyola University Medical Center","ror":"https://ror.org/05xcyt367","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1304196042","https://openalex.org/I1304269903"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jawed Fareed","raw_affiliation_strings":["Loyola University Medical Center, Maywood, Ill., and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Loyola University Medical Center, Maywood, Ill., and","institution_ids":["https://openalex.org/I1304196042"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.5831,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.75725845,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"12","issue":"2","first_page":"73","last_page":"80"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10285","display_name":"Venous Thromboembolism Diagnosis and Management","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10285","display_name":"Venous Thromboembolism Diagnosis and Management","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12402","display_name":"Travel-related health issues","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/venous-thromboembolism","display_name":"venous thromboembolism","score":0.9810000061988831},{"id":"https://openalex.org/keywords/air-travel","display_name":"air travel","score":0.878000020980835},{"id":"https://openalex.org/keywords/long-haul-flights","display_name":"long-haul flights","score":0.75},{"id":"https://openalex.org/keywords/thrombophilia","display_name":"thrombophilia","score":0.8690000176429749},{"id":"https://openalex.org/keywords/factor-v-leiden","display_name":"factor V Leiden","score":0.8379999995231628},{"id":"https://openalex.org/keywords/activated-protein-c-resistance","display_name":"activated protein C resistance","score":0.8840000033378601},{"id":"https://openalex.org/keywords/prothrombin-gene-mutation","display_name":"prothrombin gene mutation","score":0.8930000066757202},{"id":"https://openalex.org/keywords/antiphospholipid-antibodies","display_name":"antiphospholipid antibodies","score":0.9850000143051147},{"id":"https://openalex.org/keywords/protein-s-deficiency","display_name":"protein S deficiency","score":0.8109999895095825},{"id":"https://openalex.org/keywords/protein-c-deficiency","display_name":"protein C deficiency","score":0.9900000095367432},{"id":"https://openalex.org/keywords/hyperhomocysteinemia","display_name":"hyperhomocysteinemia","score":0.9710000157356262},{"id":"https://openalex.org/keywords/immobility","display_name":"immobility","score":0.6809999942779541},{"id":"https://openalex.org/keywords/dehydration","display_name":"dehydration","score":0.578000009059906},{"id":"https://openalex.org/keywords/oral-contraceptives","display_name":"oral contraceptives","score":0.7039999961853027},{"id":"https://openalex.org/keywords/thromboprophylaxis","display_name":"thromboprophylaxis","score":0.8519999980926514},{"id":"https://openalex.org/keywords/compression-stockings","display_name":"compression stockings","score":0.9789999723434448},{"id":"https://openalex.org/keywords/cabin-environment","display_name":"cabin environment","score":0.4300000071525574}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8499091863632202},{"id":"https://openalex.org/C2985550459","wikidata":"https://www.wikidata.org/wiki/Q376880","display_name":"Air travel","level":3,"score":0.5572559833526611},{"id":"https://openalex.org/C2780842393","wikidata":"https://www.wikidata.org/wiki/Q1570013","display_name":"Thrombophilia","level":3,"score":0.5032500624656677},{"id":"https://openalex.org/C2780011451","wikidata":"https://www.wikidata.org/wiki/Q2751330","display_name":"Venous thrombosis","level":3,"score":0.4579640030860901},{"id":"https://openalex.org/C2780868729","wikidata":"https://www.wikidata.org/wiki/Q261327","display_name":"Thrombosis","level":2,"score":0.4323940873146057},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.350456565618515},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.32305824756622314},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.20733004808425903},{"id":"https://openalex.org/C146978453","wikidata":"https://www.wikidata.org/wiki/Q3798668","display_name":"Aerospace engineering","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C74448152","wikidata":"https://www.wikidata.org/wiki/Q765633","display_name":"Aviation","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000401","descriptor_name":"Aircraft","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011322","descriptor_name":"Primary Prevention","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013923","descriptor_name":"Thromboembolism","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D013923","descriptor_name":"Thromboembolism","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D014195","descriptor_name":"Travel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1159/000069121","doi":"https://doi.org/10.1159/000069121","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000069121","pdf_url":null,"source":{"id":"https://openalex.org/S54128167","display_name":"Medical Principles and Practice","issn_l":"1011-7571","issn":["1011-7571","1423-0151"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Principles and Practice","raw_type":"journal-article"},{"id":"pmid:12634460","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12634460","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical principles and practice : international journal of the Kuwait University, Health Science Centre","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9907000064849854}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":72,"referenced_works":["https://openalex.org/W14593717","https://openalex.org/W30562015","https://openalex.org/W159656921","https://openalex.org/W305173082","https://openalex.org/W1485388354","https://openalex.org/W1490410496","https://openalex.org/W1531281563","https://openalex.org/W1616936842","https://openalex.org/W1776737152","https://openalex.org/W1845670861","https://openalex.org/W1967482017","https://openalex.org/W1969960235","https://openalex.org/W1971501970","https://openalex.org/W1972058538","https://openalex.org/W1977503236","https://openalex.org/W1977615320","https://openalex.org/W1982489617","https://openalex.org/W1993190598","https://openalex.org/W1994012560","https://openalex.org/W2004838513","https://openalex.org/W2007827330","https://openalex.org/W2013608204","https://openalex.org/W2019746767","https://openalex.org/W2019934651","https://openalex.org/W2025304357","https://openalex.org/W2041816955","https://openalex.org/W2043306284","https://openalex.org/W2048051936","https://openalex.org/W2055547103","https://openalex.org/W2059524251","https://openalex.org/W2065231049","https://openalex.org/W2067073483","https://openalex.org/W2067086317","https://openalex.org/W2075196907","https://openalex.org/W2079180127","https://openalex.org/W2080400564","https://openalex.org/W2081488805","https://openalex.org/W2081645946","https://openalex.org/W2083592362","https://openalex.org/W2087773001","https://openalex.org/W2092735129","https://openalex.org/W2094070926","https://openalex.org/W2094723148","https://openalex.org/W2095901921","https://openalex.org/W2103056192","https://openalex.org/W2104062454","https://openalex.org/W2114152867","https://openalex.org/W2117767595","https://openalex.org/W2125145536","https://openalex.org/W2134299894","https://openalex.org/W2160436707","https://openalex.org/W2161869349","https://openalex.org/W2163474339","https://openalex.org/W2265741365","https://openalex.org/W2283957630","https://openalex.org/W2315332792","https://openalex.org/W2342048536","https://openalex.org/W2399938969","https://openalex.org/W2403061077","https://openalex.org/W2405902444","https://openalex.org/W2407356866","https://openalex.org/W2408251402","https://openalex.org/W2411425522","https://openalex.org/W2411549574","https://openalex.org/W2414620683","https://openalex.org/W2427905563","https://openalex.org/W2443527059","https://openalex.org/W2469884802","https://openalex.org/W2578511244","https://openalex.org/W2793538523","https://openalex.org/W4247374640","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2121849249","https://openalex.org/W2023332094","https://openalex.org/W2038447671","https://openalex.org/W1909668718","https://openalex.org/W2017775109","https://openalex.org/W2162642139","https://openalex.org/W7081942006","https://openalex.org/W2614637972","https://openalex.org/W2016220980","https://openalex.org/W2465349988"],"abstract_inverted_index":{"Long-distance":[0],"air":[1,12,117,133,290],"travel":[2,13],"is":[3,26,166,210],"increasing":[4],"and":[5,20,64,75,79,84,92,156,161,175,178,225,245,253,264,269,277,292,306,318],"cases":[6],"of":[7,54,99,108,116,143,173,176,189,194,204,223,260,281,286],"venous":[8,119],"thromboembolism":[9],"(VTE)":[10],"following":[11],"have":[14],"attracted":[15],"both":[16],"considerable":[17],"public":[18],"attention":[19],"legal":[21],"claims":[22],"against":[23],"airlines.":[24],"VTE":[25,100,224,299],"a":[27,32,265,302,309],"common":[28],"disorder":[29],"worldwide":[30],"with":[31,51,140],"notably":[33],"high":[34],"incidence":[35],"in":[36,111,158,217,226],"older":[37],"individuals.":[38],"Many":[39],"biochemical":[40],"factors":[41,57,104,125,129,136],"that":[42,168,212,230,247,273,297],"lead":[43],"to,":[44],"or":[45,197],"accentuate,":[46],"thrombus":[47],"formation":[48],"are":[49,94,102,126],"associated":[50,139],"increased":[52],"risk":[53,98],"VTE.":[55,190,287],"These":[56],"include":[58,137],"thrombophilia,":[59],"activated":[60],"protein":[61,73,76],"C":[62,77],"resistance":[63],"factor":[65],"V":[66],"Leiden,":[67],"prothrombin":[68],"gene":[69],"mutation,":[70],"antiphospholipid":[71],"antibodies,":[72],"S":[74],"deficiencies,":[78],"methylene":[80],"tetrahydrofolate":[81],"reductase":[82],"polymorphism":[83],"homocysteinemia.":[85],"Individual":[86],"physical":[87],"characteristics":[88],"including":[89],"age,":[90],"weight":[91],"height":[93],"significant":[95],"for":[96,182,311],"personal":[97],"as":[101,106],"other":[103,162],"such":[105],"use":[107],"oral":[109],"contraceptives":[110],"women.":[112],"In":[113],"the":[114,127,151,187,221,258,279,316],"case":[115],"travel-related":[118,298],"thrombosis,":[120],"superimposed":[121],"upon":[122],"these":[123],"individual":[124],"environmental":[128],"directly":[130],"related":[131],"to":[132,150,207,238,249,283,321],"travel.":[134],"Travel-related":[135],"stasis":[138],"prolonged":[141,250],"periods":[142],"immobility,":[144],"physiological":[145],"stresses":[146],"resulting":[147],"from":[148],"exposure":[149],"cabin":[152,267],"environment":[153,268],"(low":[154],"humidity":[155],"hypoxia)":[157],"long-haul":[159,289],"flight":[160],"in-flight":[163,198],"factors.":[164],"It":[165,209],"suggested":[167],"passenger":[169,228],"behavior":[170],"(movement,":[171],"avoidance":[172],"dehydration":[174],"alcohol)":[177],"appropriate":[179],"pharmacological":[180],"prophylaxis":[181,192],"high-risk":[183],"travelers":[184],"can":[185,231],"reduce":[186,232],"likelihood":[188],"Physical":[191],"(use":[193],"compression":[195],"stockings":[196],"exercise":[199],"devices)":[200],"may":[201,300],"also":[202,236],"be":[203],"general":[205],"benefit":[206],"passengers.":[208],"recommended":[211],"airlines":[213],"become":[214],"more":[215],"proactive":[216],"educating":[218],"passengers":[219],"concerning":[220],"dangers":[222,285],"promoting":[227],"actions":[229],"risk.":[233],"Airlines":[234],"should":[235,256,270],"work":[237],"avoid":[239],"cramped":[240],"seating":[241,262],"conditions":[242,263],"(seat":[243],"size":[244],"pitch)":[246],"contribute":[248],"immobility.":[251],"Governments":[252],"regulatory":[254],"authorities":[255],"mandate":[257],"provision":[259],"adequate":[261],"good":[266],"support":[271],"studies":[272],"will":[274],"define":[275],"risks":[276],"determine":[278],"efficacy":[280],"protocols":[282],"minimize":[284],"Increased":[288],"traffic":[291],"an":[293],"aging":[294],"population":[295],"suggest":[296],"present":[301],"growing":[303],"healthcare":[304],"threat":[305],"has":[307],"highlighted":[308],"need":[310],"additional":[312],"biomedical":[313],"research":[314],"into":[315],"causes":[317],"potential":[319],"solutions":[320],"this":[322],"problem.":[323]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2013,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}