{"id":"https://openalex.org/W2084465019","doi":"https://doi.org/10.1016/j.bej.2013.09.006","title":"Simulation for the recovery of plasmid for a DNA vaccine","display_name":"Simulation for the recovery of plasmid for a DNA vaccine","publication_year":2013,"publication_date":"2013-09-16","ids":{"openalex":"https://openalex.org/W2084465019","doi":"https://doi.org/10.1016/j.bej.2013.09.006","mag":"2084465019"},"language":"en","primary_location":{"id":"doi:10.1016/j.bej.2013.09.006","doi":"https://doi.org/10.1016/j.bej.2013.09.006","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bej.2013.09.006","pdf_url":null,"source":{"id":"https://openalex.org/S168210271","display_name":"Biochemical Engineering Journal","issn_l":"1369-703X","issn":["1369-703X","1873-295X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical Engineering Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045572356","display_name":"Miladys Limonta Fern\u00e1ndez","orcid":"https://orcid.org/0000-0002-1664-5255","observed_orcids":["https://orcid.org/0000-0002-1664-5255"]},"institutions":[{"id":"https://openalex.org/I4210130720","display_name":"Centro de Ingenier\u00eda Gen\u00e9tica y Biotecnolog\u00eda","ror":"https://ror.org/03qxwgf98","country_code":"CU","type":"facility","lineage":["https://openalex.org/I4210130720"]}],"countries":["CU"],"is_corresponding":true,"raw_author_name":"Miladys Limonta","raw_affiliation_strings":["Center for Genetic Engineering and Biotechnology, Ave 31 e/158 y 190, PO Box 6162, ZIP 10600, Havana 10600, Cuba"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Genetic Engineering and Biotechnology, Ave 31 e/158 y 190, PO Box 6162, ZIP 10600, Havana 10600, Cuba","institution_ids":["https://openalex.org/I4210130720"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080511965","display_name":"Nika Lendero Krajnc","orcid":"https://orcid.org/0000-0003-4769-0988","observed_orcids":["https://orcid.org/0000-0003-4769-0988"]},"institutions":[{"id":"https://openalex.org/I2957750942","display_name":"BIA Separations (Slovenia)","ror":"https://ror.org/03f2kwz12","country_code":"SI","type":"company","lineage":["https://openalex.org/I2957750942"]}],"countries":["SI"],"is_corresponding":false,"raw_author_name":"Nika Lendero Krajnc","raw_affiliation_strings":["BIA Separations, Mirce 21, SI-5270 Ajdovscina, Slovenia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BIA Separations, Mirce 21, SI-5270 Ajdovscina, Slovenia","institution_ids":["https://openalex.org/I2957750942"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086140175","display_name":"Ur\u0161ka Vidic","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2957750942","display_name":"BIA Separations (Slovenia)","ror":"https://ror.org/03f2kwz12","country_code":"SI","type":"company","lineage":["https://openalex.org/I2957750942"]}],"countries":["SI"],"is_corresponding":false,"raw_author_name":"Ur\u0161ka Vidic","raw_affiliation_strings":["BIA Separations, Mirce 21, SI-5270 Ajdovscina, Slovenia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BIA Separations, Mirce 21, SI-5270 Ajdovscina, Slovenia","institution_ids":["https://openalex.org/I2957750942"]}]},{"author_position":"last","author":{"id":null,"display_name":"Lourdes Zumalac\u00e1rregui","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I908025542","display_name":"Polytechnic Jos\u00e9 Antonio Echeverr\u00eda","ror":"https://ror.org/0573cnq15","country_code":"CU","type":"education","lineage":["https://openalex.org/I908025542"]}],"countries":["CU"],"is_corresponding":false,"raw_author_name":"Lourdes Zumalac\u00e1rregui","raw_affiliation_strings":["Higher Polytechnic Institute Jos\u00e9 Antonio Echeverr\u00eda, Havana, Cuba"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Higher Polytechnic Institute Jos\u00e9 Antonio Echeverr\u00eda, Havana, Cuba","institution_ids":["https://openalex.org/I908025542"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5045572356"],"corresponding_institution_ids":["https://openalex.org/I4210130720"],"apc_list":{"value":3820,"currency":"USD","value_usd":3820},"apc_paid":null,"fwci":0.2016,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.43995416,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"80","issue":null,"first_page":"14","last_page":"18"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11124","display_name":"Protein purification and stability","score":0.9531000256538391,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11124","display_name":"Protein purification and stability","score":0.9531000256538391,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11663","display_name":"Viral Infectious Diseases and Gene Expression in Insects","score":0.01769999973475933,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11053","display_name":"Process Optimization and Integration","score":0.007000000216066837,"subfield":{"id":"https://openalex.org/subfields/2207","display_name":"Control and Systems Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/plasmid-recovery","display_name":"plasmid recovery","score":0.8159999847412109},{"id":"https://openalex.org/keywords/dna-vaccine","display_name":"DNA vaccine","score":0.8579999804496765},{"id":"https://openalex.org/keywords/plasmid-purification","display_name":"plasmid DNA purification","score":0.859000027179718},{"id":"https://openalex.org/keywords/production-cost-optimization","display_name":"production cost optimization","score":0.8169999718666077},{"id":"https://openalex.org/keywords/superpro-designer","display_name":"SuperPro Designer","score":0.7649999856948853},{"id":"https://openalex.org/keywords/experimental-design","display_name":"experimental design","score":0.4749999940395355}],"concepts":[{"id":"https://openalex.org/C22744801","wikidata":"https://www.wikidata.org/wiki/Q172778","display_name":"Plasmid","level":3,"score":0.79307621717453},{"id":"https://openalex.org/C167508917","wikidata":"https://www.wikidata.org/wiki/Q578537","display_name":"DNA vaccination","level":4,"score":0.7115375995635986},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.47895127534866333},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.45001664757728577},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.43225038051605225},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3439190685749054},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.3416762351989746},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.33138149976730347},{"id":"https://openalex.org/C183696295","wikidata":"https://www.wikidata.org/wiki/Q2487696","display_name":"Biochemical engineering","level":1,"score":0.3247358500957489},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.1851786971092224}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.bej.2013.09.006","doi":"https://doi.org/10.1016/j.bej.2013.09.006","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bej.2013.09.006","pdf_url":null,"source":{"id":"https://openalex.org/S168210271","display_name":"Biochemical Engineering Journal","issn_l":"1369-703X","issn":["1369-703X","1873-295X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical Engineering Journal","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/12","score":0.6000000238418579,"display_name":"Responsible consumption and production"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":7,"referenced_works":["https://openalex.org/W631921326","https://openalex.org/W2018033335","https://openalex.org/W2029582445","https://openalex.org/W2035345152","https://openalex.org/W2091856445","https://openalex.org/W2135221612","https://openalex.org/W2490395854"],"related_works":["https://openalex.org/W1985993322","https://openalex.org/W1510838092","https://openalex.org/W3089409189","https://openalex.org/W4213136775","https://openalex.org/W2030494942","https://openalex.org/W3142691414","https://openalex.org/W2562534964","https://openalex.org/W2086776312","https://openalex.org/W7135883462","https://openalex.org/W3119938259"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2015,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}