{"id":"https://openalex.org/W2083947579","doi":"https://doi.org/10.1002/cam4.364","title":"Clinical outcomes associated with evolving treatment modalities and radiation techniques for base\u2010of\u2010tongue carcinoma: thirty years of institutional experience","display_name":"Clinical outcomes associated with evolving treatment modalities and radiation techniques for base\u2010of\u2010tongue carcinoma: thirty years of institutional experience","publication_year":2015,"publication_date":"2015-01-26","ids":{"openalex":"https://openalex.org/W2083947579","doi":"https://doi.org/10.1002/cam4.364","mag":"2083947579","pmid":"https://pubmed.ncbi.nlm.nih.gov/25620682","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4430258"},"language":"en","primary_location":{"id":"doi:10.1002/cam4.364","doi":"https://doi.org/10.1002/cam4.364","is_oa":true,"landing_page_url":"https://doi.org/10.1002/cam4.364","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cam4.364","source":{"id":"https://openalex.org/S2754843627","display_name":"Cancer Medicine","issn_l":"2045-7634","issn":["2045-7634"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cam4.364","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055362184","display_name":"Leechuan Andy Chen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]},{"id":"https://openalex.org/I2801159745","display_name":"Huntsman Cancer Institute","ror":"https://ror.org/03v7tx966","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801159745","https://openalex.org/I4210148268"]},{"id":"https://openalex.org/I4210148268","display_name":"University of Utah Health Care","ror":"https://ror.org/047s7ex42","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210148268"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Leechuan Andy Chen","raw_affiliation_strings":["Department of Radiation Oncology, Huntsman Cancer Hospital, University of Utah, Salt Lake City, Utah"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Huntsman Cancer Hospital, University of Utah, Salt Lake City, Utah","institution_ids":["https://openalex.org/I223532165","https://openalex.org/I2801159745","https://openalex.org/I4210148268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019007483","display_name":"Christopher James Anker","orcid":"https://orcid.org/0000-0002-3230-1815","observed_orcids":["https://orcid.org/0000-0002-3230-1815"]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]},{"id":"https://openalex.org/I2801159745","display_name":"Huntsman Cancer Institute","ror":"https://ror.org/03v7tx966","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801159745","https://openalex.org/I4210148268"]},{"id":"https://openalex.org/I4210148268","display_name":"University of Utah Health Care","ror":"https://ror.org/047s7ex42","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210148268"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher J. Anker","raw_affiliation_strings":["Department of Radiation Oncology, Huntsman Cancer Hospital, University of Utah, Salt Lake City, Utah"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Huntsman Cancer Hospital, University of Utah, Salt Lake City, Utah","institution_ids":["https://openalex.org/I223532165","https://openalex.org/I2801159745","https://openalex.org/I4210148268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111724338","display_name":"Jason P. Hunt","orcid":"https://orcid.org/0000-0001-8762-3750","observed_orcids":["https://orcid.org/0000-0001-8762-3750"]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jason P. Hunt","raw_affiliation_strings":["Division of Otolaryngology Head and Neck Surgery Department of Surgery University of Utah Salt Lake City Utah"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Otolaryngology Head and Neck Surgery Department of Surgery University of Utah Salt Lake City Utah","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041634253","display_name":"Luke O. Buchmann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Luke O. Buchmann","raw_affiliation_strings":["Division of Otolaryngology Head and Neck Surgery Department of Surgery University of Utah Salt Lake City Utah"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Otolaryngology Head and Neck Surgery Department of Surgery University of Utah Salt Lake City Utah","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073549408","display_name":"Kenneth F. Grossmann","orcid":"https://orcid.org/0000-0002-8523-7407","observed_orcids":["https://orcid.org/0000-0002-8523-7407"]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kenneth F. Grossmann","raw_affiliation_strings":["Division of Oncology, Department of Internal Medicine, University of Utah, Salt Lake City, Utah"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Oncology, Department of Internal Medicine, University of Utah, Salt Lake City, Utah","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082070319","display_name":"Kenneth M. Boucher","orcid":"https://orcid.org/0000-0003-2833-0127","observed_orcids":["https://orcid.org/0000-0003-2833-0127"]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kenneth Boucher","raw_affiliation_strings":["Study Design and Biostatistics Center Division of Epidemiology and Public Health Department of Internal Medicine University of Utah Salt Lake City Utah"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Study Design and Biostatistics Center Division of Epidemiology and Public Health Department of Internal Medicine University of Utah Salt Lake City Utah","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102135285","display_name":"Li\u2010Ming Christine Fang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Li\u2010Ming Christine Fang","raw_affiliation_strings":["Department of Radiation Oncology; University of Washington; Seattle Washington"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology; University of Washington; Seattle Washington","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035423539","display_name":"Dennis C. Shrieve","orcid":"https://orcid.org/0000-0002-9212-7249","observed_orcids":["https://orcid.org/0000-0002-9212-7249"]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]},{"id":"https://openalex.org/I2801159745","display_name":"Huntsman Cancer Institute","ror":"https://ror.org/03v7tx966","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801159745","https://openalex.org/I4210148268"]},{"id":"https://openalex.org/I4210148268","display_name":"University of Utah Health Care","ror":"https://ror.org/047s7ex42","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210148268"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dennis C. Shrieve","raw_affiliation_strings":["Department of Radiation Oncology, Huntsman Cancer Hospital, University of Utah, Salt Lake City, Utah"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Huntsman Cancer Hospital, University of Utah, Salt Lake City, Utah","institution_ids":["https://openalex.org/I223532165","https://openalex.org/I2801159745","https://openalex.org/I4210148268"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038585533","display_name":"Ying J. Hitchcock","orcid":"https://orcid.org/0000-0002-2151-6597","observed_orcids":["https://orcid.org/0000-0002-2151-6597"]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]},{"id":"https://openalex.org/I2801159745","display_name":"Huntsman Cancer Institute","ror":"https://ror.org/03v7tx966","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801159745","https://openalex.org/I4210148268"]},{"id":"https://openalex.org/I4210148268","display_name":"University of Utah Health Care","ror":"https://ror.org/047s7ex42","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210148268"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Ying J. Hitchcock","raw_affiliation_strings":["Department of Radiation Oncology, Huntsman Cancer Hospital, University of Utah, Salt Lake City, Utah"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Huntsman Cancer Hospital, University of Utah, Salt Lake City, Utah","institution_ids":["https://openalex.org/I223532165","https://openalex.org/I2801159745","https://openalex.org/I4210148268"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5038585533"],"corresponding_institution_ids":["https://openalex.org/I223532165","https://openalex.org/I2801159745","https://openalex.org/I4210148268"],"apc_list":{"value":4700,"currency":"USD","value_usd":4700},"apc_paid":{"value":4700,"currency":"USD","value_usd":4700},"fwci":3.1819,"has_fulltext":true,"cited_by_count":15,"citation_normalized_percentile":{"value":0.91529827,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"4","issue":"5","first_page":"651","last_page":"660"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11669","display_name":"Head and Neck Surgical Oncology","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10619","display_name":"Esophageal Cancer Research and Treatment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/base-of-tongue-squamous-cell-carcinoma","display_name":"base of tongue squamous cell carcinoma","score":0.9850000143051147},{"id":"https://openalex.org/keywords/definitive-chemoradiotherapy","display_name":"definitive chemoradiotherapy","score":0.8889999985694885},{"id":"https://openalex.org/keywords/intensity-modulated-radiotherapy","display_name":"intensity-modulated radiotherapy","score":0.9369999766349792},{"id":"https://openalex.org/keywords/simultaneous-integrated-boost","display_name":"simultaneous integrated boost","score":0.9909999966621399},{"id":"https://openalex.org/keywords/external-beam-radiotherapy","display_name":"external beam radiotherapy","score":0.878000020980835},{"id":"https://openalex.org/keywords/interstitial-brachytherapy","display_name":"interstitial brachytherapy","score":0.9940000176429749},{"id":"https://openalex.org/keywords/locoregional-control","display_name":"locoregional control","score":0.9549999833106995},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.9599999785423279},{"id":"https://openalex.org/keywords/functional-preservation","display_name":"functional preservation","score":0.5170000195503235},{"id":"https://openalex.org/keywords/head-and-neck-cancer","display_name":"head and neck cancer","score":0.7210000157356262}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8999627828598022},{"id":"https://openalex.org/C2778424827","wikidata":"https://www.wikidata.org/wiki/Q5090613","display_name":"Chemoradiotherapy","level":3,"score":0.642340898513794},{"id":"https://openalex.org/C2777416452","wikidata":"https://www.wikidata.org/wiki/Q896687","display_name":"Brachytherapy","level":3,"score":0.6402926445007324},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.6136033535003662},{"id":"https://openalex.org/C2775908122","wikidata":"https://www.wikidata.org/wiki/Q3070621","display_name":"External beam radiotherapy","level":4,"score":0.4485548436641693},{"id":"https://openalex.org/C3020606620","wikidata":"https://www.wikidata.org/wiki/Q179661","display_name":"Treatment modality","level":2,"score":0.44723042845726013},{"id":"https://openalex.org/C2779903281","wikidata":"https://www.wikidata.org/wiki/Q6888026","display_name":"Modalities","level":2,"score":0.4457196593284607},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.4343307912349701},{"id":"https://openalex.org/C3020003399","wikidata":"https://www.wikidata.org/wiki/Q3070621","display_name":"External beam radiation","level":3,"score":0.4302941560745239},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.4165959060192108},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.37198662757873535},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.36786532402038574},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3657546639442444},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3320455551147461},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C36289849","wikidata":"https://www.wikidata.org/wiki/Q34749","display_name":"Social science","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002277","descriptor_name":"Carcinoma","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D002277","descriptor_name":"Carcinoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D002277","descriptor_name":"Carcinoma","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D003131","descriptor_name":"Combined Modality Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003952","descriptor_name":"Diagnostic Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009367","descriptor_name":"Neoplasm Staging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014062","descriptor_name":"Tongue Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D014062","descriptor_name":"Tongue Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D014062","descriptor_name":"Tongue Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017024","descriptor_name":"Chemotherapy, Adjuvant","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D018714","descriptor_name":"Radiotherapy, Adjuvant","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D018714","descriptor_name":"Radiotherapy, Adjuvant","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1002/cam4.364","doi":"https://doi.org/10.1002/cam4.364","is_oa":true,"landing_page_url":"https://doi.org/10.1002/cam4.364","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cam4.364","source":{"id":"https://openalex.org/S2754843627","display_name":"Cancer Medicine","issn_l":"2045-7634","issn":["2045-7634"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Medicine","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3397932","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4430258","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4430258","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4430258","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Med","raw_type":"Text"},{"id":"pmid:25620682","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25620682","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer medicine","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1002/cam4.364","doi":"https://doi.org/10.1002/cam4.364","is_oa":true,"landing_page_url":"https://doi.org/10.1002/cam4.364","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cam4.364","source":{"id":"https://openalex.org/S2754843627","display_name":"Cancer Medicine","issn_l":"2045-7634","issn":["2045-7634"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9922999739646912,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2083947579.pdf","grobid_xml":"https://content.openalex.org/works/W2083947579.grobid-xml"},"referenced_works_count":34,"referenced_works":["https://openalex.org/W1966183433","https://openalex.org/W1970562765","https://openalex.org/W1982614562","https://openalex.org/W1989845540","https://openalex.org/W1996655864","https://openalex.org/W2014368010","https://openalex.org/W2018841481","https://openalex.org/W2018988769","https://openalex.org/W2023840357","https://openalex.org/W2043453187","https://openalex.org/W2046917312","https://openalex.org/W2056844160","https://openalex.org/W2060180628","https://openalex.org/W2061565656","https://openalex.org/W2066677235","https://openalex.org/W2075639390","https://openalex.org/W2079816780","https://openalex.org/W2094771992","https://openalex.org/W2102940690","https://openalex.org/W2108731588","https://openalex.org/W2109398754","https://openalex.org/W2110664940","https://openalex.org/W2124760608","https://openalex.org/W2133173262","https://openalex.org/W2140110477","https://openalex.org/W2144907895","https://openalex.org/W2148443353","https://openalex.org/W2148825988","https://openalex.org/W2151415400","https://openalex.org/W2164367977","https://openalex.org/W2169877681","https://openalex.org/W2172200669","https://openalex.org/W4231621249","https://openalex.org/W4248456080"],"related_works":["https://openalex.org/W2051563317","https://openalex.org/W2073357410","https://openalex.org/W2070009230","https://openalex.org/W2083475386","https://openalex.org/W2589220519","https://openalex.org/W2056628147","https://openalex.org/W1979538212","https://openalex.org/W2590017937","https://openalex.org/W7096809039","https://openalex.org/W2090371945"],"abstract_inverted_index":{"Curative":[0],"treatment":[1,19,29,164,207],"for":[2,17,35],"base-of-tongue":[3],"squamous":[4],"cell":[5],"carcinoma":[6],"(BOT":[7],"SCC)":[8],"has":[9,208],"evolved":[10,106,117],"over":[11],"time;":[12],"however,":[13],"comparative":[14],"outcomes":[15,96,229],"analysis":[16],"various":[18],"strategies":[20],"is":[21],"lacking.":[22],"The":[23],"authors":[24],"reviewed":[25],"the":[26,141,201],"evolution":[27],"of":[28,136,159],"modality":[30,100,105],"and":[31,46,63,95,145,151,173,192,220,227],"radiotherapy":[32],"(RT)":[33],"technique":[34,116],"231":[36],"consecutive":[37],"BOT":[38,205],"SCC":[39,206],"patients":[40],"at":[41],"our":[42],"institution":[43],"between":[44],"1981":[45],"2011.":[47],"Treatment":[48,104],"modalities":[49],"included":[50,69],"definitive":[51,55,108,112,179],"chemoradiotherapy":[52],"(chemoRT)":[53],"(42%),":[54],"RT":[56,61,67,102,109,115,222],"(33%),":[57],"surgery":[58,64],"followed":[59],"by":[60,99],"(20%),":[62],"alone":[65],"(5%).":[66],"techniques":[68],"external":[70],"beam":[71],"plus":[72],"interstitial":[73],"brachytherapy":[74],"(EBRT":[75],"+":[76,120,129,182],"IB)":[77],"(37%),":[78],"conventional":[79,124,198],"EBRT":[80,119,125],"(29%),":[81],"intensity-modulated":[82],"radiation":[83],"therapy":[84],"\u00b1":[85,90],"simultaneous":[86],"integrated":[87],"boost":[88],"(IMRT":[89],"SIB)":[91],"(34%).":[92],"Clinical":[93],"characteristics":[94],"were":[97,148],"stratified":[98],"or":[101],"technique.":[103],"from":[107,118],"(1980s-1990s)":[110,122],"to":[111,123,127,178,197],"chemoRT":[113,167],"(1990s-2000s).":[114],"IB":[121],"(1990s-2000s)":[126],"IMRT":[128,181,234],"SIB":[130,183],"(2000s).":[131],"With":[132],"median":[133],"alive":[134],"follow-up":[135],"6":[137],"years":[138],"(0.3-28":[139],"years),":[140],"5-year":[142],"LC,":[143],"LRC,":[144],"OS":[146,174,193],"rates":[147],"80%,":[149],"73%,":[150],"51%.":[152],"There":[153],"was":[154],"no":[155],"difference":[156],"in":[157],"distribution":[158],"gender,":[160],"age,":[161],"stage":[162],"among":[163],"modalities.":[165],"Definitive":[166],"had":[168,184],"improved":[169,185],"LRC":[170,186],"(HR":[171,175,187,190,194],"1.6)":[172],"1.7)":[176],"compared":[177,196],"RT.":[180],"3.2),":[188],"DFS":[189],"3.4),":[191],"3.0)":[195],"EBRT.":[199],"Over":[200],"past":[202],"30":[203],"years,":[204],"undergone":[209],"major":[210],"paradigm":[211],"shifts":[212],"that":[213],"incorporate":[214],"nonsurgical":[215],"functional":[216],"preservation,":[217],"concurrent":[218],"chemotherapy,":[219],"advanced":[221],"techniques.":[223],"Excellent":[224],"locoregional":[225],"control":[226],"survival":[228],"are":[230],"associated":[231],"with":[232,235],"accelerated":[233],"chemotherapy.":[236]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}