{"id":"https://openalex.org/W2083170375","doi":"https://doi.org/10.1016/0378-1119(87)90130-2","title":"Pseudorabies virus as a live virus vector for expression of foreign genes","display_name":"Pseudorabies virus as a live virus vector for expression of foreign genes","publication_year":1987,"publication_date":"1987-01-01","ids":{"openalex":"https://openalex.org/W2083170375","doi":"https://doi.org/10.1016/0378-1119(87)90130-2","mag":"2083170375","pmid":"https://pubmed.ncbi.nlm.nih.gov/2826296"},"language":"en","primary_location":{"id":"doi:10.1016/0378-1119(87)90130-2","doi":"https://doi.org/10.1016/0378-1119(87)90130-2","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0378-1119(87)90130-2","pdf_url":null,"source":{"id":"https://openalex.org/S75702506","display_name":"Gene","issn_l":"0378-1119","issn":["0378-1119","1879-0038"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gene","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111919583","display_name":"Darrell R. Thomsen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Darrell R. Thomsen","raw_affiliation_strings":["Molecular Biology Research, Upjohn Company, Kalamazoo, MI 49001"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular Biology Research, Upjohn Company, Kalamazoo, MI 49001","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112007539","display_name":"Keith R. Marotti","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Keith R. Marotti","raw_affiliation_strings":["Molecular Biology Research, The Upjohn Company, Kalamazoo, MI 49001 U.S.A. Tel. (616)385-6934"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular Biology Research, The Upjohn Company, Kalamazoo, MI 49001 U.S.A. Tel. (616)385-6934","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113555334","display_name":"Daniel P. Palermo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Daniel P. Palermo","raw_affiliation_strings":["Molecular Biology Research, The Upjohn Company, Kalamazoo, MI 49001 U.S.A. Tel. (616)385-8411"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular Biology Research, The Upjohn Company, Kalamazoo, MI 49001 U.S.A. Tel. (616)385-8411","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085037854","display_name":"Leonard E. Post","orcid":"https://orcid.org/0009-0007-5779-4146","observed_orcids":["https://orcid.org/0009-0007-5779-4146"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Leonard E. Post","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5085037854"],"corresponding_institution_ids":[],"apc_list":{"value":3300,"currency":"USD","value_usd":3300},"apc_paid":null,"fwci":2.0723,"has_fulltext":false,"cited_by_count":54,"citation_normalized_percentile":{"value":0.8722611,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"57","issue":"2-3","first_page":"261","last_page":"265"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.5356000065803528,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.5356000065803528,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11495","display_name":"Animal Virus Infections Studies","score":0.1858000010251999,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11663","display_name":"Viral Infectious Diseases and Gene Expression in Insects","score":0.1071000024676323,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pseudorabies-virus","display_name":"pseudorabies virus","score":1.0},{"id":"https://openalex.org/keywords/live-attenuated-vaccine-vector","display_name":"live attenuated vaccine vector","score":0.8109999895095825},{"id":"https://openalex.org/keywords/tissue-plasminogen-activator","display_name":"tissue plasminogen activator","score":0.9490000009536743},{"id":"https://openalex.org/keywords/recombinant-viruses","display_name":"recombinant virus","score":0.6439999938011169},{"id":"https://openalex.org/keywords/foreign-gene-expression","display_name":"foreign gene expression","score":0.7400000095367432},{"id":"https://openalex.org/keywords/plasmid-recombination","display_name":"plasmid recombination","score":0.7149999737739563},{"id":"https://openalex.org/keywords/transfection","display_name":"transfection","score":0.38100001215934753}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9223623275756836},{"id":"https://openalex.org/C2781092067","wikidata":"https://www.wikidata.org/wiki/Q316180","display_name":"Pseudorabies","level":3,"score":0.9028126001358032},{"id":"https://openalex.org/C187882448","wikidata":"https://www.wikidata.org/wiki/Q283478","display_name":"Complementary DNA","level":3,"score":0.7398927211761475},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.6926913261413574},{"id":"https://openalex.org/C22744801","wikidata":"https://www.wikidata.org/wiki/Q172778","display_name":"Plasmid","level":3,"score":0.677947461605072},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.6246405839920044},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.5669230222702026},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.5300763845443726},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5167714357376099},{"id":"https://openalex.org/C2780098074","wikidata":"https://www.wikidata.org/wiki/Q6037362","display_name":"Insert (composites)","level":2,"score":0.49266964197158813},{"id":"https://openalex.org/C202878990","wikidata":"https://www.wikidata.org/wiki/Q830465","display_name":"Capsid","level":3,"score":0.4648773670196533},{"id":"https://openalex.org/C33161422","wikidata":"https://www.wikidata.org/wiki/Q5421712","display_name":"Expression vector","level":4,"score":0.4260508418083191},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.15763360261917114},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003001","descriptor_name":"Cloning, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005822","descriptor_name":"Genetic Vectors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010957","descriptor_name":"Plasmids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010959","descriptor_name":"Tissue Plasminogen Activator","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D010959","descriptor_name":"Tissue Plasminogen Activator","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011558","descriptor_name":"Herpesvirus 1, Suid","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D014612","descriptor_name":"Vaccines","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0378-1119(87)90130-2","doi":"https://doi.org/10.1016/0378-1119(87)90130-2","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0378-1119(87)90130-2","pdf_url":null,"source":{"id":"https://openalex.org/S75702506","display_name":"Gene","issn_l":"0378-1119","issn":["0378-1119","1879-0038"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gene","raw_type":"journal-article"},{"id":"pmid:2826296","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2826296","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gene","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8199999928474426,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","score":0.6499999761581421,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W1756377026","https://openalex.org/W1929764420","https://openalex.org/W1986090612","https://openalex.org/W2013413617","https://openalex.org/W2025657713","https://openalex.org/W2027690720","https://openalex.org/W2038431234","https://openalex.org/W2064248292","https://openalex.org/W2068476525","https://openalex.org/W2077174145","https://openalex.org/W2083813448","https://openalex.org/W2086996422","https://openalex.org/W2092377354","https://openalex.org/W2092815481","https://openalex.org/W2147664066","https://openalex.org/W2154964754","https://openalex.org/W2415114669","https://openalex.org/W4301425546"],"related_works":["https://openalex.org/W2605009530","https://openalex.org/W3163484558","https://openalex.org/W958139911","https://openalex.org/W2087002064","https://openalex.org/W2394230923","https://openalex.org/W2200381240","https://openalex.org/W2389416872","https://openalex.org/W2364167399","https://openalex.org/W2375429125","https://openalex.org/W2387939543"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}