{"id":"https://openalex.org/W2083085161","doi":"https://doi.org/10.1093/eurheartj/4.suppl_c.33","title":"Calcium and cell death","display_name":"Calcium and cell death","publication_year":1983,"publication_date":"1983-05-02","ids":{"openalex":"https://openalex.org/W2083085161","doi":"https://doi.org/10.1093/eurheartj/4.suppl_c.33","mag":"2083085161","pmid":"https://pubmed.ncbi.nlm.nih.gov/6352269"},"language":"en","primary_location":{"id":"doi:10.1093/eurheartj/4.suppl_c.33","doi":"https://doi.org/10.1093/eurheartj/4.suppl_c.33","is_oa":false,"landing_page_url":"https://doi.org/10.1093/eurheartj/4.suppl_c.33","pdf_url":null,"source":{"id":"https://openalex.org/S181568219","display_name":"European Heart Journal","issn_l":"0195-668X","issn":["0195-668X","1522-9645"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Heart Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111700482","display_name":"W. G. Nayler","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I2800453128","display_name":"Austin Hospital","ror":"https://ror.org/010mv7n52","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2800453128","https://openalex.org/I4210163497"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"W. G. Nayler","raw_affiliation_strings":["Department of Medicine, University of Melbourne, Austin Hospital Heidelberg, Victoria, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of Melbourne, Austin Hospital Heidelberg, Victoria, Australia","institution_ids":["https://openalex.org/I165779595","https://openalex.org/I2800453128"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5111700482"],"corresponding_institution_ids":["https://openalex.org/I165779595","https://openalex.org/I2800453128"],"apc_list":{"value":5240,"currency":"EUR","value_usd":5922},"apc_paid":null,"fwci":6.0517,"has_fulltext":false,"cited_by_count":103,"citation_normalized_percentile":{"value":0.96373949,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"4","issue":"suppl C","first_page":"33","last_page":"41"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11057","display_name":"Cardiac Ischemia and Reperfusion","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11057","display_name":"Cardiac Ischemia and Reperfusion","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/calcium-overload","display_name":"calcium overload","score":0.8880000114440918},{"id":"https://openalex.org/keywords/myocardial-cell-death","display_name":"myocardial cell death","score":0.6570000052452087},{"id":"https://openalex.org/keywords/calcium-influx","display_name":"calcium influx","score":0.48100000619888306},{"id":"https://openalex.org/keywords/ischemic-myocardium","display_name":"ischemic myocardium","score":0.5630000233650208},{"id":"https://openalex.org/keywords/ischemia-reperfusion-injury","display_name":"ischemia-reperfusion injury","score":0.7940000295639038},{"id":"https://openalex.org/keywords/cardioprotection","display_name":"cardioprotection","score":0.8429999947547913},{"id":"https://openalex.org/keywords/hypothermia","display_name":"hypothermia","score":0.8410000205039978},{"id":"https://openalex.org/keywords/nifedipine","display_name":"nifedipine","score":0.9990000128746033},{"id":"https://openalex.org/keywords/phosphocreatine","display_name":"phosphocreatine","score":0.9919999837875366},{"id":"https://openalex.org/keywords/mitochondrial-atp-synthesis","display_name":"mitochondrial ATP production","score":0.7099999785423279},{"id":"https://openalex.org/keywords/rabbit-heart","display_name":"rabbit heart","score":0.5080000162124634}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8704044818878174},{"id":"https://openalex.org/C161191863","wikidata":"https://www.wikidata.org/wiki/Q199655","display_name":"Library science","level":1,"score":0.46054691076278687},{"id":"https://openalex.org/C3017595490","wikidata":"https://www.wikidata.org/wiki/Q17006263","display_name":"University hospital","level":2,"score":0.41197651624679565},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.37305039167404175},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000255","descriptor_name":"Adenosine Triphosphate","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000860","descriptor_name":"Hypoxia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D003327","descriptor_name":"Coronary Disease","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006324","descriptor_name":"Heart Arrest, Induced","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009543","descriptor_name":"Nifedipine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D010477","descriptor_name":"Perfusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011188","descriptor_name":"Potassium","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066298","descriptor_name":"In Vitro Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/eurheartj/4.suppl_c.33","doi":"https://doi.org/10.1093/eurheartj/4.suppl_c.33","is_oa":false,"landing_page_url":"https://doi.org/10.1093/eurheartj/4.suppl_c.33","pdf_url":null,"source":{"id":"https://openalex.org/S181568219","display_name":"European Heart Journal","issn_l":"0195-668X","issn":["0195-668X","1522-9645"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Heart Journal","raw_type":"journal-article"},{"id":"pmid:6352269","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6352269","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European heart journal","raw_type":"Journal Article"},{"id":"pmh:oai:open-archive.highwire.org:ehj:4/suppl_C/33","doi":null,"is_oa":false,"landing_page_url":"http://eurheartj.oxfordjournals.org/cgi/content/short/4/suppl_C/33","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2053572659","https://openalex.org/W2416548982","https://openalex.org/W2435908001","https://openalex.org/W4243153859","https://openalex.org/W1978486188","https://openalex.org/W1965764242","https://openalex.org/W2118973454","https://openalex.org/W2360112364","https://openalex.org/W2056517908","https://openalex.org/W2016596917"],"abstract_inverted_index":{"Irrespective":[0],"of":[1,16,34,40,61,123,125,129,133,142,146,156],"age":[2],"or":[3],"species,":[4],"injured":[5],"cardiac":[6],"myocytes":[7],"accumulate":[8],"Ca2+.":[9],"In":[10,103],"this":[11],"paper":[12],"four":[13],"different":[14],"aspects":[15,23],"the":[17,25,31,37,41,58,110,130,143,147,153],"Ca2+-overloading":[18],"phenomenon":[19],"are":[20,160],"discussed.":[21],"These":[22,149],"include":[24],"conditions":[26],"under":[27],"which":[28],"it":[29],"occurs,":[30],"possible":[32,46],"routes":[33],"Ca2+":[35,44],"entry,":[36],"metabolic":[38],"consequences":[39],"raised":[42],"tissue":[43,131],"and":[45,63,68,92,96,114,137,140,158],"protective":[47,51],"procedures.":[48],"The":[49],"particular":[50],"procedures":[52],"that":[53,152],"will":[54],"be":[55],"described":[56],"involve":[57],"combined":[59],"use":[60],"hypothermia":[62,159],"nifedipine":[64,106,157],"(50":[65],"micrograms/l),":[66],"with":[67,113],"without":[69,115],"K+-induced":[70,116],"chemical":[71],"cardioplegia.":[72,117],"Isolated,":[73],"electrically":[74],"paced":[75],"rabbit":[76],"hearts":[77],"were":[78],"made":[79],"ischaemic":[80],"for":[81],"60":[82],"to":[83,109],"180":[84],"min":[85],"at":[86,99],"37,":[87],"28,":[88],"25,":[89],"15,":[90],"12":[91],"5":[93],"degrees":[94,101],"C":[95],"then":[97],"reperfused":[98],"37":[100],"C.":[102],"some":[104],"experiments":[105],"was":[107,119],"added":[108],"perfusion":[111],"buffer,":[112],"Recovery":[118],"assessed":[120],"in":[121],"terms":[122],"recovery":[124],"mechanical":[126],"function,":[127],"maintenance":[128,141],"stores":[132],"adenosine":[134],"5'-triphosphate":[135],"(ATP)":[136],"creatine":[138],"phosphate,":[139],"ATP-generating":[144],"activity":[145],"mitochondria.":[148],"results":[150],"show":[151],"cardioprotective":[154],"effects":[155],"additive.":[161]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}