{"id":"https://openalex.org/W2082931608","doi":"https://doi.org/10.1038/nrn2761","title":"Neural stem cell systems: physiological players or in vitro entities?","display_name":"Neural stem cell systems: physiological players or in vitro entities?","publication_year":2010,"publication_date":"2010-01-28","ids":{"openalex":"https://openalex.org/W2082931608","doi":"https://doi.org/10.1038/nrn2761","mag":"2082931608","pmid":"https://pubmed.ncbi.nlm.nih.gov/20107441"},"language":"en","primary_location":{"id":"doi:10.1038/nrn2761","doi":"https://doi.org/10.1038/nrn2761","is_oa":true,"landing_page_url":"https://doi.org/10.1038/nrn2761","pdf_url":"https://www.nature.com/articles/nrn2761.pdf","source":{"id":"https://openalex.org/S26843219","display_name":"Nature reviews. Neuroscience","issn_l":"1471-003X","issn":["1471-003X","1471-0048"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-2","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Reviews Neuroscience","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.nature.com/articles/nrn2761.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047383675","display_name":"Luciano Conti","orcid":"https://orcid.org/0000-0002-2050-9846","observed_orcids":["https://orcid.org/0000-0002-2050-9846"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Luciano Conti","raw_affiliation_strings":["Department of Pharmacological Sciences and Center for Stem Cell Research, University of Milan, Via Balzaretti 9, Milan, Italy. luciano.conti@unimi.it","Department of Pharmacological Sciences and Center for Stem Cell Research, University of Milan, Milano, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacological Sciences and Center for Stem Cell Research, University of Milan, Via Balzaretti 9, Milan, Italy. luciano.conti@unimi.it","institution_ids":["https://openalex.org/I189158943"]},{"raw_affiliation_string":"Department of Pharmacological Sciences and Center for Stem Cell Research, University of Milan, Milano, Italy","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042005526","display_name":"Elena F. Cattaneo","orcid":"https://orcid.org/0000-0002-0755-4917","observed_orcids":["https://orcid.org/0000-0002-0755-4917"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Elena Cattaneo","raw_affiliation_strings":["Department of Pharmacological Sciences and Center for Stem Cell Research, University of Milan, Via Balzaretti 9, Milano, 20133, Italy","Department of Pharmacological Sciences and Center for Stem Cell Research, University of Milan, Milano, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacological Sciences and Center for Stem Cell Research, University of Milan, Via Balzaretti 9, Milano, 20133, Italy","institution_ids":["https://openalex.org/I189158943"]},{"raw_affiliation_string":"Department of Pharmacological Sciences and Center for Stem Cell Research, University of Milan, Milano, Italy","institution_ids":["https://openalex.org/I189158943"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I189158943"],"apc_list":null,"apc_paid":null,"fwci":2.9841,"has_fulltext":true,"cited_by_count":333,"citation_normalized_percentile":{"value":0.95973154,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"11","issue":"3","first_page":"176","last_page":"187"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neural-stem-cells","display_name":"neural stem cells","score":0.9980000257492065},{"id":"https://openalex.org/keywords/neural-precursors","display_name":"neuronal precursors","score":0.718999981880188},{"id":"https://openalex.org/keywords/central-nervous-system-development","display_name":"central nervous system development","score":0.8320000171661377},{"id":"https://openalex.org/keywords/neural-stem-cell-transplantation","display_name":"neural stem cell transplantation","score":0.6349999904632568},{"id":"https://openalex.org/keywords/regenerative-medicine","display_name":"regenerative medicine","score":0.6880000233650208},{"id":"https://openalex.org/keywords/stem-cell-fate-control","display_name":"stem cell fate control","score":0.6669999957084656},{"id":"https://openalex.org/keywords/endogenous-neural-stem-cells","display_name":"endogenous neural stem cells","score":0.7319999933242798}],"concepts":[{"id":"https://openalex.org/C136834591","wikidata":"https://www.wikidata.org/wiki/Q2944097","display_name":"Neural stem cell","level":3,"score":0.7834385633468628},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6619747281074524},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.4995605945587158},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4621243476867676},{"id":"https://openalex.org/C2986949344","wikidata":"https://www.wikidata.org/wiki/Q9404","display_name":"Neural system","level":2,"score":0.4341103136539459},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.4248260259628296},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3681012988090515},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.1653481423854828},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.16149204969406128},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D018929","descriptor_name":"Cell Culture Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019070","descriptor_name":"Cell Lineage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D039902","descriptor_name":"Multipotent Stem Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D055495","descriptor_name":"Neurogenesis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1038/nrn2761","doi":"https://doi.org/10.1038/nrn2761","is_oa":true,"landing_page_url":"https://doi.org/10.1038/nrn2761","pdf_url":"https://www.nature.com/articles/nrn2761.pdf","source":{"id":"https://openalex.org/S26843219","display_name":"Nature reviews. Neuroscience","issn_l":"1471-003X","issn":["1471-003X","1471-0048"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-2","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Reviews Neuroscience","raw_type":"journal-article"},{"id":"pmid:20107441","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20107441","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature reviews. Neuroscience","raw_type":"Journal Article"},{"id":"pmh:oai:iris.unitn.it:11572/99128","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11572/99128","pdf_url":null,"source":{"id":"https://openalex.org/S4306401913","display_name":"Institutional Research Information System (Universit\u00e0 degli Studi di Trento)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193223587","host_organization_name":"University of Trento","host_organization_lineage":["https://openalex.org/I193223587"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:zenodo.org:3443968","doi":null,"is_oa":true,"landing_page_url":"https://zenodo.org/record/3443968","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1038/nrn2761","doi":"https://doi.org/10.1038/nrn2761","is_oa":true,"landing_page_url":"https://doi.org/10.1038/nrn2761","pdf_url":"https://www.nature.com/articles/nrn2761.pdf","source":{"id":"https://openalex.org/S26843219","display_name":"Nature reviews. Neuroscience","issn_l":"1471-003X","issn":["1471-003X","1471-0048"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-2","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Reviews Neuroscience","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.7246000170707703,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4618763421","display_name":"European Consortium for Systematic Stem Cell Biology","funder_award_id":"200720","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G586769283","display_name":"European Consortium for Stem Cell Therapy for Neurodegenerative Diseases","funder_award_id":"222943","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G9000506289","display_name":"Cellule staminali neurali ad alta capacita\u2019 integrativa e rilascianti BDNF per approcci trapiantologici in un modello animale di Corea di Huntington","funder_award_id":"20074MW29N","funder_id":"https://openalex.org/F4320321873","funder_display_name":"Ministero dell\u2019Istruzione, dell\u2019Universit\u00e0 e della Ricerca"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320321499","display_name":"Fondazione Cariplo","ror":"https://ror.org/01gb56c55"},{"id":"https://openalex.org/F4320321873","display_name":"Ministero dell\u2019Istruzione, dell\u2019Universit\u00e0 e della Ricerca","ror":"https://ror.org/0166hxq48"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2082931608.pdf","grobid_xml":"https://content.openalex.org/works/W2082931608.grobid-xml"},"referenced_works_count":148,"referenced_works":["https://openalex.org/W66655770","https://openalex.org/W313255239","https://openalex.org/W1516412274","https://openalex.org/W1543151032","https://openalex.org/W1547812429","https://openalex.org/W1555753016","https://openalex.org/W1643680178","https://openalex.org/W1834737933","https://openalex.org/W1859089489","https://openalex.org/W1928907742","https://openalex.org/W1964448607","https://openalex.org/W1965421340","https://openalex.org/W1965681567","https://openalex.org/W1968983678","https://openalex.org/W1970092837","https://openalex.org/W1970610673","https://openalex.org/W1971689054","https://openalex.org/W1972022525","https://openalex.org/W1974372416","https://openalex.org/W1979895839","https://openalex.org/W1980217666","https://openalex.org/W1981444928","https://openalex.org/W1982227030","https://openalex.org/W1984412074","https://openalex.org/W1986636341","https://openalex.org/W1987085702","https://openalex.org/W1988976106","https://openalex.org/W1989346221","https://openalex.org/W1989920563","https://openalex.org/W1990935914","https://openalex.org/W1992949513","https://openalex.org/W1996449402","https://openalex.org/W1997496613","https://openalex.org/W1998167315","https://openalex.org/W1998502499","https://openalex.org/W1998641354","https://openalex.org/W1999348847","https://openalex.org/W1999970417","https://openalex.org/W2004421565","https://openalex.org/W2005765981","https://openalex.org/W2005797914","https://openalex.org/W2005891911","https://openalex.org/W2006718746","https://openalex.org/W2008204763","https://openalex.org/W2009498071","https://openalex.org/W2013596279","https://openalex.org/W2014851648","https://openalex.org/W2016024994","https://openalex.org/W2017603170","https://openalex.org/W2018235103","https://openalex.org/W2018354332","https://openalex.org/W2020539766","https://openalex.org/W2020682158","https://openalex.org/W2021692265","https://openalex.org/W2021766835","https://openalex.org/W2022970384","https://openalex.org/W2024174118","https://openalex.org/W2025618811","https://openalex.org/W2026541878","https://openalex.org/W2029073164","https://openalex.org/W2032170619","https://openalex.org/W2033822105","https://openalex.org/W2036045423","https://openalex.org/W2039623436","https://openalex.org/W2042962824","https://openalex.org/W2044025778","https://openalex.org/W2044691783","https://openalex.org/W2045081995","https://openalex.org/W2045899482","https://openalex.org/W2046006021","https://openalex.org/W2047098628","https://openalex.org/W2048784291","https://openalex.org/W2049271482","https://openalex.org/W2049795516","https://openalex.org/W2053911973","https://openalex.org/W2055561480","https://openalex.org/W2057881187","https://openalex.org/W2060902761","https://openalex.org/W2062118486","https://openalex.org/W2064488884","https://openalex.org/W2065564965","https://openalex.org/W2065737043","https://openalex.org/W2065754676","https://openalex.org/W2065839907","https://openalex.org/W2069252618","https://openalex.org/W2070306500","https://openalex.org/W2074498796","https://openalex.org/W2077442285","https://openalex.org/W2077654978","https://openalex.org/W2079356804","https://openalex.org/W2080777953","https://openalex.org/W2080790343","https://openalex.org/W2081978832","https://openalex.org/W2083237272","https://openalex.org/W2084518736","https://openalex.org/W2084652820","https://openalex.org/W2085006580","https://openalex.org/W2086943348","https://openalex.org/W2087028472","https://openalex.org/W2087786585","https://openalex.org/W2088814620","https://openalex.org/W2089558318","https://openalex.org/W2090042357","https://openalex.org/W2092895250","https://openalex.org/W2093377304","https://openalex.org/W2093885717","https://openalex.org/W2095389581","https://openalex.org/W2095649629","https://openalex.org/W2096592632","https://openalex.org/W2099525640","https://openalex.org/W2100007797","https://openalex.org/W2103275847","https://openalex.org/W2105361655","https://openalex.org/W2106483894","https://openalex.org/W2109610561","https://openalex.org/W2111635840","https://openalex.org/W2112485709","https://openalex.org/W2113964043","https://openalex.org/W2115687722","https://openalex.org/W2117058176","https://openalex.org/W2123480238","https://openalex.org/W2125908939","https://openalex.org/W2125987139","https://openalex.org/W2127220436","https://openalex.org/W2131032423","https://openalex.org/W2132164731","https://openalex.org/W2132367339","https://openalex.org/W2137887198","https://openalex.org/W2138977668","https://openalex.org/W2139208934","https://openalex.org/W2143372016","https://openalex.org/W2146882327","https://openalex.org/W2148908764","https://openalex.org/W2149647101","https://openalex.org/W2150014868","https://openalex.org/W2150806446","https://openalex.org/W2150817988","https://openalex.org/W2152069828","https://openalex.org/W2153067767","https://openalex.org/W2155228504","https://openalex.org/W2159884201","https://openalex.org/W2162008350","https://openalex.org/W2165900361","https://openalex.org/W2165921475","https://openalex.org/W2166261688","https://openalex.org/W2168945089","https://openalex.org/W2169160857","https://openalex.org/W2341491220"],"related_works":["https://openalex.org/W2386159836","https://openalex.org/W2349943139","https://openalex.org/W2146294525","https://openalex.org/W3091818966","https://openalex.org/W2763023381","https://openalex.org/W2463180394","https://openalex.org/W2067303448","https://openalex.org/W2436637417","https://openalex.org/W2413607582","https://openalex.org/W2793570060"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":9},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":17},{"year":2020,"cited_by_count":17},{"year":2019,"cited_by_count":20},{"year":2018,"cited_by_count":22},{"year":2017,"cited_by_count":15},{"year":2016,"cited_by_count":26},{"year":2015,"cited_by_count":31},{"year":2014,"cited_by_count":23},{"year":2013,"cited_by_count":33},{"year":2012,"cited_by_count":33}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}