{"id":"https://openalex.org/W2082917893","doi":"https://doi.org/10.1055/s-2006-950299","title":"Asymmetric Syntheses of 3,4-Substituted Tetrahydroquinoline Derivatives by (-)-Sparteine-Mediated Dynamic Thermodynamic Resolution of 2-(\u03b1-Lithiobenzyl)-N-pivaloylaniline","display_name":"Asymmetric Syntheses of 3,4-Substituted Tetrahydroquinoline Derivatives by (-)-Sparteine-Mediated Dynamic Thermodynamic Resolution of 2-(\u03b1-Lithiobenzyl)-N-pivaloylaniline","publication_year":2006,"publication_date":"2006-11-01","ids":{"openalex":"https://openalex.org/W2082917893","doi":"https://doi.org/10.1055/s-2006-950299","mag":"2082917893"},"language":"en","primary_location":{"id":"doi:10.1055/s-2006-950299","doi":"https://doi.org/10.1055/s-2006-950299","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-2006-950299","pdf_url":null,"source":{"id":"https://openalex.org/S197964166","display_name":"Synthesis","issn_l":"0039-7881","issn":["0039-7881","1437-210X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Synthesis","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110162037","display_name":"Yong Park","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yong Park","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114378051","display_name":"Yong\u2010Tae Kim","orcid":"https://orcid.org/0000-0001-9263-9116","observed_orcids":["https://orcid.org/0000-0001-9263-9116"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yongtae Kim","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110618272","display_name":"Eun\u2010kyoung Shin","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Eun-kyoung Shin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5072926516","display_name":"Peter Andrew Beak","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Peter Beak","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2003,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.53535335,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"2006","issue":"22","first_page":"3805","last_page":"3808"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10013","display_name":"Asymmetric Synthesis and Catalysis","score":0.8076000213623047,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10013","display_name":"Asymmetric Synthesis and Catalysis","score":0.8076000213623047,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12228","display_name":"Coordination Chemistry and Organometallics","score":0.09529999643564224,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13649","display_name":"Advanced Synthetic Organic Chemistry","score":0.051100000739097595,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dynamic-kinetic-resolution","display_name":"dynamic kinetic resolution","score":0.6510000228881836},{"id":"https://openalex.org/keywords/sparteine","display_name":"sparteine","score":0.9110000133514404},{"id":"https://openalex.org/keywords/epimerization","display_name":"epimerization","score":0.75},{"id":"https://openalex.org/keywords/asymmetric-synthesis","display_name":"asymmetric synthesis","score":0.7039999961853027},{"id":"https://openalex.org/keywords/tetrahydroquinolines","display_name":"tetrahydroquinolines","score":0.949999988079071},{"id":"https://openalex.org/keywords/chiral-amines","display_name":"chiral amines","score":0.5509999990463257}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9615814685821533},{"id":"https://openalex.org/C2778694420","wikidata":"https://www.wikidata.org/wiki/Q419552","display_name":"Sparteine","level":2,"score":0.8812309503555298},{"id":"https://openalex.org/C203130289","wikidata":"https://www.wikidata.org/wiki/Q926272","display_name":"Epimer","level":2,"score":0.7831814289093018},{"id":"https://openalex.org/C146686406","wikidata":"https://www.wikidata.org/wiki/Q898628","display_name":"Enantioselective synthesis","level":3,"score":0.4793282747268677},{"id":"https://openalex.org/C138268822","wikidata":"https://www.wikidata.org/wiki/Q1051925","display_name":"Resolution (logic)","level":2,"score":0.4686070680618286},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.4075998067855835},{"id":"https://openalex.org/C147597530","wikidata":"https://www.wikidata.org/wiki/Q369472","display_name":"Computational chemistry","level":1,"score":0.37782421708106995},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.36177271604537964},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.33091849088668823},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.11579862236976624},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1055/s-2006-950299","doi":"https://doi.org/10.1055/s-2006-950299","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-2006-950299","pdf_url":null,"source":{"id":"https://openalex.org/S197964166","display_name":"Synthesis","issn_l":"0039-7881","issn":["0039-7881","1437-210X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Synthesis","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2951921422","https://openalex.org/W2028551744","https://openalex.org/W2950023457","https://openalex.org/W1889787711","https://openalex.org/W1971462175","https://openalex.org/W2075666413","https://openalex.org/W2152266208","https://openalex.org/W1989893889","https://openalex.org/W2583065060","https://openalex.org/W2035799198"],"abstract_inverted_index":{"(-)-Sparteine-mediated":[0],"dynamic":[1],"thermodynamic":[2],"resolution":[3],"of":[4,21,34,41],"2-(\u03b1-lithiobenzyl)-N-pivaloylaniline":[5],"was":[6],"investigated.":[7],"A":[8],"temperature-":[9],"and":[10,43],"concentration-controlled":[11],"epimerization-substitution":[12],"sequence":[13],"provides":[14],"a":[15,22],"simple":[16,36],"protocol":[17],"for":[18],"the":[19],"preparation":[20],"highly":[23],"enantioenriched":[24],"benzyl-substituted":[25],"N-pivaloylaniline":[26],"product":[27],"(up":[28],"to":[29,38],"98:2":[30],"er).":[31],"Also,":[32],"application":[33],"this":[35],"methodology":[37],"asymmetric":[39],"syntheses":[40],"1,3,4-":[42],"3,4-substituted":[44],"tetrahydroquinoline":[45],"derivatives":[46],"is":[47],"demonstrated.":[48]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2016-06-24T00:00:00"}