{"id":"https://openalex.org/W2082837801","doi":"https://doi.org/10.1016/0006-291x(77)90979-2","title":"Expression of ligandin and glutathione S-transferase activities by cells in tissue culture","display_name":"Expression of ligandin and glutathione S-transferase activities by cells in tissue culture","publication_year":1977,"publication_date":"1977-06-01","ids":{"openalex":"https://openalex.org/W2082837801","doi":"https://doi.org/10.1016/0006-291x(77)90979-2","mag":"2082837801","pmid":"https://pubmed.ncbi.nlm.nih.gov/409396"},"language":"en","primary_location":{"id":"doi:10.1016/0006-291x(77)90979-2","doi":"https://doi.org/10.1016/0006-291x(77)90979-2","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0006-291x(77)90979-2","pdf_url":null,"source":{"id":"https://openalex.org/S151589183","display_name":"Biochemical and Biophysical Research Communications","issn_l":"0006-291X","issn":["0006-291X","1090-2104"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical and Biophysical Research Communications","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Garry J. Smith","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I84392919","display_name":"Temple University","ror":"https://ror.org/00kx1jb78","country_code":"US","type":"education","lineage":["https://openalex.org/I84392919"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Garry J. Smith","raw_affiliation_strings":["Fels Research Institute and Department of Biochemistry Temple University School of Medicine Philadelphia, Pa., USA 19140"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fels Research Institute and Department of Biochemistry Temple University School of Medicine Philadelphia, Pa., USA 19140","institution_ids":["https://openalex.org/I84392919"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111570513","display_name":"Kay Huebner","orcid":"https://orcid.org/0000-0002-2848-1382","observed_orcids":["https://orcid.org/0000-0002-2848-1382"]},"institutions":[{"id":"https://openalex.org/I102322052","display_name":"The Wistar Institute","ror":"https://ror.org/04wncat98","country_code":"US","type":"facility","lineage":["https://openalex.org/I102322052"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kay Huebner","raw_affiliation_strings":["Wistar Institute of Anatomy and Biology Philadelphia, Pa., USA 19104"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wistar Institute of Anatomy and Biology Philadelphia, Pa., USA 19104","institution_ids":["https://openalex.org/I102322052"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062814155","display_name":"Gerald Litwack","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I84392919","display_name":"Temple University","ror":"https://ror.org/00kx1jb78","country_code":"US","type":"education","lineage":["https://openalex.org/I84392919"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Gerald Litwack","raw_affiliation_strings":["Fels Research Institute and Department of Biochemistry Temple University School of Medicine Philadelphia, Pa., USA 19140"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fels Research Institute and Department of Biochemistry Temple University School of Medicine Philadelphia, Pa., USA 19140","institution_ids":["https://openalex.org/I84392919"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5062814155"],"corresponding_institution_ids":["https://openalex.org/I84392919"],"apc_list":{"value":3110,"currency":"USD","value_usd":3110},"apc_paid":null,"fwci":0.7396,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.67005076,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"76","issue":"4","first_page":"1174","last_page":"1180"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12187","display_name":"Glutathione Transferases and Polymorphisms","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12187","display_name":"Glutathione Transferases and Polymorphisms","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11884","display_name":"Redox biology and oxidative stress","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glutathione-s-transferase","display_name":"glutathione S-transferase","score":0.9800000190734863},{"id":"https://openalex.org/keywords/ligandin","display_name":"ligandin","score":0.9900000095367432},{"id":"https://openalex.org/keywords/dinitrochlorobenzene","display_name":"1-chloro-2,4-dinitrobenzene","score":0.925000011920929},{"id":"https://openalex.org/keywords/enzyme-activity","display_name":"enzyme activity","score":0.4180000126361847},{"id":"https://openalex.org/keywords/transformed-cell-lines","display_name":"transformed cell lines","score":0.8600000143051147},{"id":"https://openalex.org/keywords/hybrid-cell-lines","display_name":"hybrid cell lines","score":0.9259999990463257},{"id":"https://openalex.org/keywords/antigenic-relatedness","display_name":"antigenic relatedness","score":0.7680000066757202}],"concepts":[{"id":"https://openalex.org/C2776907368","wikidata":"https://www.wikidata.org/wiki/Q307302","display_name":"Glutathione S-transferase","level":4,"score":0.8292292356491089},{"id":"https://openalex.org/C538909803","wikidata":"https://www.wikidata.org/wiki/Q116907","display_name":"Glutathione","level":3,"score":0.7222625017166138},{"id":"https://openalex.org/C2776376580","wikidata":"https://www.wikidata.org/wiki/Q407355","display_name":"Transferase","level":3,"score":0.648396372795105},{"id":"https://openalex.org/C3019047270","wikidata":"https://www.wikidata.org/wiki/Q307302","display_name":"Glutathione transferase","level":4,"score":0.609560489654541},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.5984001755714417},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.5679494738578796},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.49112650752067566},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4806031882762909},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.4472280740737915},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4362061619758606},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.3802183270454407},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.36783671379089355},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.09166479110717773}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002471","descriptor_name":"Cell Transformation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003600","descriptor_name":"Cytosol","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D004137","descriptor_name":"Dinitrochlorobenzene","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D005779","descriptor_name":"Immunodiffusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005982","descriptor_name":"Glutathione Transferase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013045","descriptor_name":"Species Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D046508","descriptor_name":"Culture Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0006-291x(77)90979-2","doi":"https://doi.org/10.1016/0006-291x(77)90979-2","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0006-291x(77)90979-2","pdf_url":null,"source":{"id":"https://openalex.org/S151589183","display_name":"Biochemical and Biophysical Research Communications","issn_l":"0006-291X","issn":["0006-291X","1090-2104"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical and Biophysical Research Communications","raw_type":"journal-article"},{"id":"pmid:409396","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/409396","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical and biophysical research communications","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W1538140157","https://openalex.org/W1557712139","https://openalex.org/W1559475786","https://openalex.org/W1581414347","https://openalex.org/W1775749144","https://openalex.org/W1982956186","https://openalex.org/W1988182888","https://openalex.org/W2027459106","https://openalex.org/W2030386408","https://openalex.org/W2040930057","https://openalex.org/W2055181572","https://openalex.org/W2071140420","https://openalex.org/W2091477263","https://openalex.org/W2095287334","https://openalex.org/W2157695429","https://openalex.org/W2160200829","https://openalex.org/W2225741354","https://openalex.org/W2285458529","https://openalex.org/W2314003586","https://openalex.org/W2341808352"],"related_works":["https://openalex.org/W2041788909","https://openalex.org/W2399473357","https://openalex.org/W2003679209","https://openalex.org/W2083441762","https://openalex.org/W2028385110","https://openalex.org/W2136018712","https://openalex.org/W2073165634","https://openalex.org/W67263357","https://openalex.org/W2339845327","https://openalex.org/W2064895876"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}