{"id":"https://openalex.org/W2082631942","doi":"https://doi.org/10.1073/pnas.242729199","title":"A photocleavable fluorescent nucleotide for DNA sequencing and analysis","display_name":"A photocleavable fluorescent nucleotide for DNA sequencing and analysis","publication_year":2003,"publication_date":"2003-01-06","ids":{"openalex":"https://openalex.org/W2082631942","doi":"https://doi.org/10.1073/pnas.242729199","mag":"2082631942","pmid":"https://pubmed.ncbi.nlm.nih.gov/12515853","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/141009"},"language":"en","primary_location":{"id":"doi:10.1073/pnas.242729199","doi":"https://doi.org/10.1073/pnas.242729199","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.242729199","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/141009","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Zengmin Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zengmin Li","raw_affiliation_strings":["Columbia Genome Center, Columbia University College of Physicians and Surgeons, New York, NY 10032; and Departments of Chemical Engineering and Chemistry, Columbia University, New York, NY 10027"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Columbia Genome Center, Columbia University College of Physicians and Surgeons, New York, NY 10032; and Departments of Chemical Engineering and Chemistry, Columbia University, New York, NY 10027","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006543775","display_name":"Xiaopeng Bai","orcid":"https://orcid.org/0000-0002-4016-5876","observed_orcids":["https://orcid.org/0000-0002-4016-5876"]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiaopeng Bai","raw_affiliation_strings":["Columbia Genome Center, Columbia University College of Physicians and Surgeons, New York, NY 10032; and Departments of Chemical Engineering and Chemistry, Columbia University, New York, NY 10027"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Columbia Genome Center, Columbia University College of Physicians and Surgeons, New York, NY 10032; and Departments of Chemical Engineering and Chemistry, Columbia University, New York, NY 10027","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041587384","display_name":"Hameer Ruparel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hameer Ruparel","raw_affiliation_strings":["Columbia Genome Center, Columbia University College of Physicians and Surgeons, New York, NY 10032; and Departments of Chemical Engineering and Chemistry, Columbia University, New York, NY 10027"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Columbia Genome Center, Columbia University College of Physicians and Surgeons, New York, NY 10032; and Departments of Chemical Engineering and Chemistry, Columbia University, New York, NY 10027","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090220697","display_name":"Sobin Kim","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sobin Kim","raw_affiliation_strings":["Columbia Genome Center, Columbia University College of Physicians and Surgeons, New York, NY 10032; and Departments of Chemical Engineering and Chemistry, Columbia University, New York, NY 10027"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Columbia Genome Center, Columbia University College of Physicians and Surgeons, New York, NY 10032; and Departments of Chemical Engineering and Chemistry, Columbia University, New York, NY 10027","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110885322","display_name":"Nicholas J. Turro","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nicholas J. Turro","raw_affiliation_strings":["Columbia Genome Center, Columbia University College of Physicians and Surgeons, New York, NY 10032; and Departments of Chemical Engineering and Chemistry, Columbia University, New York, NY 10027"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Columbia Genome Center, Columbia University College of Physicians and Surgeons, New York, NY 10032; and Departments of Chemical Engineering and Chemistry, Columbia University, New York, NY 10027","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084552494","display_name":"Jingyue Ju","orcid":"https://orcid.org/0000-0002-4974-4241","observed_orcids":["https://orcid.org/0000-0002-4974-4241"]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jingyue Ju","raw_affiliation_strings":["Columbia Genome Center, Columbia University College of Physicians and Surgeons, New York, NY 10032; and Departments of Chemical Engineering and Chemistry, Columbia University, New York, NY 10027"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Columbia Genome Center, Columbia University College of Physicians and Surgeons, New York, NY 10032; and Departments of Chemical Engineering and Chemistry, Columbia University, New York, NY 10027","institution_ids":["https://openalex.org/I78577930"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I78577930"],"apc_list":null,"apc_paid":null,"fwci":1.9803,"has_fulltext":false,"cited_by_count":70,"citation_normalized_percentile":{"value":0.86100336,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"100","issue":"2","first_page":"414","last_page":"419"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.003800000064074993,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11708","display_name":"Photochromic and Fluorescence Chemistry","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fluorescent-nucleotides","display_name":"fluorescent nucleotides","score":0.7620000243186951},{"id":"https://openalex.org/keywords/bodipy-fluorophores","display_name":"BODIPY fluorophores","score":0.8299999833106995},{"id":"https://openalex.org/keywords/laser-induced-fluorescence-detection","display_name":"laser-induced fluorescence detection","score":0.7519999742507935},{"id":"https://openalex.org/keywords/nucleotide-incorporation","display_name":"nucleotide incorporation","score":0.6359999775886536},{"id":"https://openalex.org/keywords/photocleavage","display_name":"photocleavage","score":0.7110000252723694},{"id":"https://openalex.org/keywords/fluorescent-dye-release","display_name":"fluorescent dye release","score":0.4350000023841858},{"id":"https://openalex.org/keywords/nucleotide-labeling","display_name":"nucleotide labeling","score":0.6499999761581421}],"concepts":[{"id":"https://openalex.org/C512185932","wikidata":"https://www.wikidata.org/wiki/Q28745","display_name":"Nucleotide","level":3,"score":0.7230142951011658},{"id":"https://openalex.org/C2778617687","wikidata":"https://www.wikidata.org/wiki/Q2448456","display_name":"Fluorophore","level":3,"score":0.6461237668991089},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.6422227621078491},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.6266975402832031},{"id":"https://openalex.org/C2780557392","wikidata":"https://www.wikidata.org/wiki/Q523796","display_name":"Linker","level":2,"score":0.5215268731117249},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.49325031042099},{"id":"https://openalex.org/C24107716","wikidata":"https://www.wikidata.org/wiki/Q123619","display_name":"Nucleic acid","level":2,"score":0.45293760299682617},{"id":"https://openalex.org/C114851143","wikidata":"https://www.wikidata.org/wiki/Q13080815","display_name":"Single molecule real time sequencing","level":5,"score":0.4397309124469757},{"id":"https://openalex.org/C2776352584","wikidata":"https://www.wikidata.org/wiki/Q418533","display_name":"Nucleoside triphosphate","level":4,"score":0.41232678294181824},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.41216179728507996},{"id":"https://openalex.org/C51679486","wikidata":"https://www.wikidata.org/wiki/Q380546","display_name":"DNA sequencing","level":3,"score":0.3699459433555603},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.32858163118362427},{"id":"https://openalex.org/C70712619","wikidata":"https://www.wikidata.org/wiki/Q908889","display_name":"DNA sequencer","level":4,"score":0.16679596900939941},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.053892552852630615},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001710","descriptor_name":"Biotin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001896","descriptor_name":"Boron Compounds","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005456","descriptor_name":"Fluorescent Dyes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009841","descriptor_name":"Oligonucleotides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010782","descriptor_name":"Photolysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1073/pnas.242729199","doi":"https://doi.org/10.1073/pnas.242729199","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.242729199","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:177548","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/141009","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:141009","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/141009","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"},{"id":"pmid:12515853","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12515853","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences of the United States of America","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:177548","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/141009","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W1658221551","https://openalex.org/W1964558738","https://openalex.org/W1966812451","https://openalex.org/W1969460941","https://openalex.org/W1969757078","https://openalex.org/W1970508473","https://openalex.org/W1978349009","https://openalex.org/W1984071784","https://openalex.org/W1984611504","https://openalex.org/W1987146517","https://openalex.org/W1988659744","https://openalex.org/W1988676851","https://openalex.org/W1991155371","https://openalex.org/W1991394551","https://openalex.org/W1995451168","https://openalex.org/W2007698777","https://openalex.org/W2019918748","https://openalex.org/W2025735321","https://openalex.org/W2026993331","https://openalex.org/W2028989854","https://openalex.org/W2035058958","https://openalex.org/W2037794798","https://openalex.org/W2050163545","https://openalex.org/W2064039337","https://openalex.org/W2076536222","https://openalex.org/W2090652275","https://openalex.org/W2095114504","https://openalex.org/W2096884836","https://openalex.org/W2129425318","https://openalex.org/W2129937879","https://openalex.org/W2151492295","https://openalex.org/W4296495660"],"related_works":["https://openalex.org/W2137348240","https://openalex.org/W4234937123","https://openalex.org/W3005148232","https://openalex.org/W2793330843","https://openalex.org/W2075155566","https://openalex.org/W2908066449","https://openalex.org/W4406892020","https://openalex.org/W2165627034","https://openalex.org/W1977332303","https://openalex.org/W2047079103"],"abstract_inverted_index":{"DNA":[0,28,89,96,141,155,241],"sequencing":[1],"by":[2,57,87,231],"synthesis":[3,35],"during":[4],"a":[5,17,37,59,73,88,99,140,168],"polymerase":[6,90],"reaction":[7,101],"using":[8],"laser-induced":[9],"fluorescence":[10,170,204],"detection":[11,182],"is":[12,122],"an":[13,123],"approach":[14],"that":[15,79,103,118,143,167,177,191],"has":[16],"great":[18],"potential":[19],"to":[20,65,158,196,209],"increase":[21],"the":[22,32,44,49,66,80,94,109,112,119,133,136,145,154,159,163,181,184,211,220,234,240],"throughput":[23],"and":[24,34,102,217],"data":[25],"quality":[26],"of":[27,36,43,69,111,135,153,162,183,236],"sequencing.":[29],"We":[30,52,77,129],"report":[31],"design":[33],"photocleavable":[38,74,221],"fluorescent":[39,137,164,200,225],"nucleoside":[40,55],"triphosphate,":[41],"one":[42],"essential":[45],"molecules":[46],"required":[47],"for":[48,126],"sequencing-by-synthesis":[50,242],"approach.":[51,243],"synthesized":[53],"this":[54],"triphosphate":[56,71],"attaching":[58],"fluorophore,":[60],"4,4-difluoro-5,7-dimethyl-4-bora-3alpha,4alpha-diaza-s-indacene":[61],"propionic":[62],"acid":[63],"(BODIPY),":[64],"5":[67],"position":[68],"2'-deoxyuridine":[70],"via":[72],"2-nitrobenzyl":[75,222],"linker.":[76,223],"demonstrate":[78],"nucleotide":[81,120,146,238],"analogue":[82,121],"can":[83,227],"be":[84,194,228],"faithfully":[85],"incorporated":[86],"Thermo":[91,127],"Sequenase":[92],"into":[93],"growing":[95],"strand":[97],"in":[98,239],"DNA-sequencing":[100],"its":[104],"incorporation":[105],"does":[106],"not":[107,173],"hinder":[108],"addition":[110],"subsequent":[113],"nucleotide.":[114,186],"These":[115,224],"results":[116,189],"indicate":[117,190],"excellent":[124],"substrate":[125],"Sequenase.":[128],"also":[130],"systematically":[131],"studied":[132],"photocleavage":[134,232],"dye":[138],"from":[139],"molecule":[142,156],"contained":[144],"analogue.":[147],"UV":[148],"irradiation":[149],"at":[150],"340":[151],"nm":[152],"led":[157],"efficient":[160],"release":[161],"dye,":[165],"ensuring":[166],"previous":[169],"signal":[171],"did":[172],"leave":[174],"any":[175],"residue":[176],"could":[178],"interfere":[179],"with":[180,202],"next":[185],"Thus,":[187],"our":[188],"it":[192],"should":[193],"feasible":[195],"use":[197],"four":[198,212],"different":[199],"dyes":[201],"distinct":[203],"emissions":[205],"as":[206],"unique":[207],"tags":[208,226],"label":[210],"nucleotides":[213],"(A,":[214],"C,":[215],"G,":[216],"T)":[218],"through":[219],"removed":[229],"easily":[230],"after":[233],"identification":[235],"each":[237]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}