{"id":"https://openalex.org/W2082432833","doi":"https://doi.org/10.1039/c4ra14626c","title":"Vilsmeier cyclization of \u03b1-acetyl-\u03b1-aroyl ketene-N,S-acetals: direct and efficient synthesis of halogenated pyridin-2(1H)-ones","display_name":"Vilsmeier cyclization of \u03b1-acetyl-\u03b1-aroyl ketene-N,S-acetals: direct and efficient synthesis of halogenated pyridin-2(1H)-ones","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W2082432833","doi":"https://doi.org/10.1039/c4ra14626c","mag":"2082432833"},"language":"en","primary_location":{"id":"doi:10.1039/c4ra14626c","doi":"https://doi.org/10.1039/c4ra14626c","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c4ra14626c","pdf_url":null,"source":{"id":"https://openalex.org/S2481244646","display_name":"RSC Advances","issn_l":"2046-2069","issn":["2046-2069"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"RSC Advances","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103087131","display_name":"Haifeng Yu","orcid":"https://orcid.org/0000-0003-2967-0182","observed_orcids":["https://orcid.org/0000-0003-2967-0182"]},"institutions":[{"id":"https://openalex.org/I41147446","display_name":"Anshan Normal University","ror":"https://ror.org/04s5wwh39","country_code":"CN","type":"education","lineage":["https://openalex.org/I41147446"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Haifeng Yu","raw_affiliation_strings":["Anshan","Anshan Normal University","China","School of Chemistry and Life Science","School of Chemistry and Life Science Anshan Normal University Anshan China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anshan","institution_ids":[]},{"raw_affiliation_string":"Anshan Normal University","institution_ids":["https://openalex.org/I41147446"]},{"raw_affiliation_string":"China","institution_ids":[]},{"raw_affiliation_string":"School of Chemistry and Life Science","institution_ids":[]},{"raw_affiliation_string":"School of Chemistry and Life Science Anshan Normal University Anshan China","institution_ids":["https://openalex.org/I41147446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103835798","display_name":"Yongmei Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I41147446","display_name":"Anshan Normal University","ror":"https://ror.org/04s5wwh39","country_code":"CN","type":"education","lineage":["https://openalex.org/I41147446"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yongmei Zhang","raw_affiliation_strings":["Anshan","Anshan Normal University","China","School of Chemistry and Life Science","School of Chemistry and Life Science Anshan Normal University Anshan China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anshan","institution_ids":[]},{"raw_affiliation_string":"Anshan Normal University","institution_ids":["https://openalex.org/I41147446"]},{"raw_affiliation_string":"China","institution_ids":[]},{"raw_affiliation_string":"School of Chemistry and Life Science","institution_ids":[]},{"raw_affiliation_string":"School of Chemistry and Life Science Anshan Normal University Anshan China","institution_ids":["https://openalex.org/I41147446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074527328","display_name":"Tiechun Li","orcid":"https://orcid.org/0009-0004-7391-8610","observed_orcids":["https://orcid.org/0009-0004-7391-8610"]},"institutions":[{"id":"https://openalex.org/I41147446","display_name":"Anshan Normal University","ror":"https://ror.org/04s5wwh39","country_code":"CN","type":"education","lineage":["https://openalex.org/I41147446"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tiechun Li","raw_affiliation_strings":["Anshan","Anshan Normal University","China","School of Chemistry and Life Science"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anshan","institution_ids":[]},{"raw_affiliation_string":"Anshan Normal University","institution_ids":["https://openalex.org/I41147446"]},{"raw_affiliation_string":"China","institution_ids":[]},{"raw_affiliation_string":"School of Chemistry and Life Science","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061247509","display_name":"Peiqiu Liao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I184983240","display_name":"Northeast Normal University","ror":"https://ror.org/02rkvz144","country_code":"CN","type":"education","lineage":["https://openalex.org/I184983240"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Peiqiu Liao","raw_affiliation_strings":["Changchun","China","Department of Chemistry","Northeast Normal University","Department of Chemistry Northeast Normal University Changchun China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Changchun","institution_ids":[]},{"raw_affiliation_string":"China","institution_ids":[]},{"raw_affiliation_string":"Department of Chemistry","institution_ids":[]},{"raw_affiliation_string":"Northeast Normal University","institution_ids":["https://openalex.org/I184983240"]},{"raw_affiliation_string":"Department of Chemistry Northeast Normal University Changchun China","institution_ids":["https://openalex.org/I184983240"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017904678","display_name":"Quanping Diao","orcid":"https://orcid.org/0000-0001-9417-2150","observed_orcids":["https://orcid.org/0000-0001-9417-2150","https://orcid.org/0000-0002-7879-3456"]},"institutions":[{"id":"https://openalex.org/I41147446","display_name":"Anshan Normal University","ror":"https://ror.org/04s5wwh39","country_code":"CN","type":"education","lineage":["https://openalex.org/I41147446"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Quanping Diao","raw_affiliation_strings":["Anshan","Anshan Normal University","China","School of Chemistry and Life Science","School of Chemistry and Life Science Anshan Normal University Anshan China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anshan","institution_ids":[]},{"raw_affiliation_string":"Anshan Normal University","institution_ids":["https://openalex.org/I41147446"]},{"raw_affiliation_string":"China","institution_ids":[]},{"raw_affiliation_string":"School of Chemistry and Life Science","institution_ids":[]},{"raw_affiliation_string":"School of Chemistry and Life Science Anshan Normal University Anshan China","institution_ids":["https://openalex.org/I41147446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060311972","display_name":"Guang Xin","orcid":"https://orcid.org/0000-0002-1799-6436","observed_orcids":["https://orcid.org/0000-0002-1799-6436","https://orcid.org/0000-0002-7787-3673"]},"institutions":[{"id":"https://openalex.org/I41147446","display_name":"Anshan Normal University","ror":"https://ror.org/04s5wwh39","country_code":"CN","type":"education","lineage":["https://openalex.org/I41147446"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guang Xin","raw_affiliation_strings":["Anshan","Anshan Normal University","China","School of Chemistry and Life Science","School of Chemistry and Life Science Anshan Normal University Anshan China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anshan","institution_ids":[]},{"raw_affiliation_string":"Anshan Normal University","institution_ids":["https://openalex.org/I41147446"]},{"raw_affiliation_string":"China","institution_ids":[]},{"raw_affiliation_string":"School of Chemistry and Life Science","institution_ids":[]},{"raw_affiliation_string":"School of Chemistry and Life Science Anshan Normal University Anshan China","institution_ids":["https://openalex.org/I41147446"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Qingling Meng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I41147446","display_name":"Anshan Normal University","ror":"https://ror.org/04s5wwh39","country_code":"CN","type":"education","lineage":["https://openalex.org/I41147446"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qingling Meng","raw_affiliation_strings":["Anshan","Anshan Normal University","China","School of Chemistry and Life Science","School of Chemistry and Life Science Anshan Normal University Anshan China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anshan","institution_ids":[]},{"raw_affiliation_string":"Anshan Normal University","institution_ids":["https://openalex.org/I41147446"]},{"raw_affiliation_string":"China","institution_ids":[]},{"raw_affiliation_string":"School of Chemistry and Life Science","institution_ids":[]},{"raw_affiliation_string":"School of Chemistry and Life Science Anshan Normal University Anshan China","institution_ids":["https://openalex.org/I41147446"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100995093","display_name":"Dongyan Hou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I41147446","display_name":"Anshan Normal University","ror":"https://ror.org/04s5wwh39","country_code":"CN","type":"education","lineage":["https://openalex.org/I41147446"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dongyan Hou","raw_affiliation_strings":["Anshan","Anshan Normal University","China","School of Chemistry and Life Science","School of Chemistry and Life Science Anshan Normal University Anshan China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anshan","institution_ids":[]},{"raw_affiliation_string":"Anshan Normal University","institution_ids":["https://openalex.org/I41147446"]},{"raw_affiliation_string":"China","institution_ids":[]},{"raw_affiliation_string":"School of Chemistry and Life Science","institution_ids":[]},{"raw_affiliation_string":"School of Chemistry and Life Science Anshan Normal University Anshan China","institution_ids":["https://openalex.org/I41147446"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5061247509","https://openalex.org/A5103087131"],"corresponding_institution_ids":["https://openalex.org/I184983240","https://openalex.org/I41147446"],"apc_list":{"value":850,"currency":"GBP","value_usd":1042},"apc_paid":null,"fwci":0.6857,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.62498147,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":96},"biblio":{"volume":"5","issue":"15","first_page":"11293","last_page":"11296"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13208","display_name":"Synthesis of heterocyclic compounds","score":0.8935999870300293,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13208","display_name":"Synthesis of heterocyclic compounds","score":0.8935999870300293,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13876","display_name":"Chemical synthesis and pharmacological studies","score":0.07209999859333038,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13859","display_name":"Organic Chemistry Synthesis Methods","score":0.0142000000923872,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ketene-n-s-acetals","display_name":"ketene N,S-acetals","score":0.6759999990463257},{"id":"https://openalex.org/keywords/pyridinone-synthesis","display_name":"pyridinone synthesis","score":0.5659999847412109},{"id":"https://openalex.org/keywords/heterocycle-synthesis","display_name":"heterocyclic synthesis","score":0.640999972820282}],"concepts":[{"id":"https://openalex.org/C2778874822","wikidata":"https://www.wikidata.org/wiki/Q368158","display_name":"Ketene","level":2,"score":0.9273908734321594},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6722117066383362},{"id":"https://openalex.org/C2777454769","wikidata":"https://www.wikidata.org/wiki/Q11172462","display_name":"Methylene","level":2,"score":0.6135432124137878},{"id":"https://openalex.org/C155647269","wikidata":"https://www.wikidata.org/wiki/Q243455","display_name":"Medicinal chemistry","level":1,"score":0.48044440150260925},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.3731262683868408},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.3248874843120575}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1039/c4ra14626c","doi":"https://doi.org/10.1039/c4ra14626c","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c4ra14626c","pdf_url":null,"source":{"id":"https://openalex.org/S2481244646","display_name":"RSC Advances","issn_l":"2046-2069","issn":["2046-2069"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"RSC Advances","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":49,"referenced_works":["https://openalex.org/W1020912733","https://openalex.org/W1504113938","https://openalex.org/W1607885903","https://openalex.org/W1946217716","https://openalex.org/W1981861883","https://openalex.org/W1981981985","https://openalex.org/W1985790087","https://openalex.org/W2003192950","https://openalex.org/W2005907031","https://openalex.org/W2011676649","https://openalex.org/W2013931776","https://openalex.org/W2014173685","https://openalex.org/W2015522037","https://openalex.org/W2020571106","https://openalex.org/W2023576255","https://openalex.org/W2024122111","https://openalex.org/W2024788815","https://openalex.org/W2025368279","https://openalex.org/W2026616124","https://openalex.org/W2026854690","https://openalex.org/W2027237082","https://openalex.org/W2027906312","https://openalex.org/W2027925054","https://openalex.org/W2028092247","https://openalex.org/W2029472316","https://openalex.org/W2032453700","https://openalex.org/W2047010372","https://openalex.org/W2078066910","https://openalex.org/W2085328547","https://openalex.org/W2088391546","https://openalex.org/W2093306023","https://openalex.org/W2094597597","https://openalex.org/W2108364716","https://openalex.org/W2111253771","https://openalex.org/W2125401216","https://openalex.org/W2167783686","https://openalex.org/W2170593597","https://openalex.org/W2171237764","https://openalex.org/W2174783363","https://openalex.org/W2316293659","https://openalex.org/W2321744949","https://openalex.org/W2326021560","https://openalex.org/W2331349411","https://openalex.org/W2332301023","https://openalex.org/W2949136494","https://openalex.org/W2949742497","https://openalex.org/W2952107908","https://openalex.org/W2952182929","https://openalex.org/W3004643983"],"related_works":["https://openalex.org/W2950045775","https://openalex.org/W2014173685","https://openalex.org/W2047010372","https://openalex.org/W2015522037","https://openalex.org/W2020571106","https://openalex.org/W2952425114","https://openalex.org/W2949895447","https://openalex.org/W2009280385","https://openalex.org/W2952923381","https://openalex.org/W2949765247"],"abstract_inverted_index":{"An":[0],"efficient":[1],"synthetic":[2],"route":[3],"to":[4],"3-aroyl-5-formyl-4-halo":[5],"pyridin-2(1":[6],"H":[7],")-ones":[8],"has":[9],"been":[10],"developed":[11],"via":[12],"Vilsmeier":[13],"cyclization":[14],"of":[15],"2-(ethylthio(arylamino)methylene)-1-alkylbutane-1,3-dione.":[16]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2}],"updated_date":"2026-10-13T10:08:12.033832","created_date":"2016-06-24T00:00:00"}
