{"id":"https://openalex.org/W2082394093","doi":"https://doi.org/10.1103/physreve.82.046307","title":"Elongational-flow-induced scission of DNA nanotubes in laminar flow","display_name":"Elongational-flow-induced scission of DNA nanotubes in laminar flow","publication_year":2010,"publication_date":"2010-10-19","ids":{"openalex":"https://openalex.org/W2082394093","doi":"https://doi.org/10.1103/physreve.82.046307","mag":"2082394093","pmid":"https://pubmed.ncbi.nlm.nih.gov/21230390"},"language":"en","primary_location":{"id":"doi:10.1103/physreve.82.046307","doi":"https://doi.org/10.1103/physreve.82.046307","is_oa":false,"landing_page_url":"https://doi.org/10.1103/physreve.82.046307","pdf_url":null,"source":{"id":"https://openalex.org/S35412551","display_name":"Physical Review E","issn_l":"1539-3755","issn":["1539-3755","1550-2376"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","vabb-shw"],"host_organization":"https://openalex.org/P4310320261","host_organization_name":"American Physical Society","host_organization_lineage":["https://openalex.org/P4310320261"],"host_organization_lineage_names":["American Physical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physical Review E","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026136757","display_name":"Rizal F. Hariadi","orcid":"https://orcid.org/0000-0001-7840-859X","observed_orcids":["https://orcid.org/0000-0001-7840-859X"]},"institutions":[{"id":"https://openalex.org/I122411786","display_name":"California Institute of Technology","ror":"https://ror.org/05dxps055","country_code":"US","type":"education","lineage":["https://openalex.org/I122411786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rizal F. Hariadi","raw_affiliation_strings":["Department of Applied Physics, California Institute of Technology, Pasadena, California 91125, USA. hariadi@dna.caltech.edu","Department of Applied Physics, California Institute of Technology, Pasadena, California 91125, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Applied Physics, California Institute of Technology, Pasadena, California 91125, USA. hariadi@dna.caltech.edu","institution_ids":["https://openalex.org/I122411786"]},{"raw_affiliation_string":"Department of Applied Physics, California Institute of Technology, Pasadena, California 91125, USA","institution_ids":["https://openalex.org/I122411786"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5028414708","display_name":"Bernard Yurke","orcid":"https://orcid.org/0000-0003-3913-2855","observed_orcids":["https://orcid.org/0000-0003-3913-2855"]},"institutions":[{"id":"https://openalex.org/I120156002","display_name":"Boise State University","ror":"https://ror.org/02e3zdp86","country_code":"US","type":"education","lineage":["https://openalex.org/I120156002"]},{"id":"https://openalex.org/I122411786","display_name":"California Institute of Technology","ror":"https://ror.org/05dxps055","country_code":"US","type":"education","lineage":["https://openalex.org/I122411786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bernard Yurke","raw_affiliation_strings":["Department of Applied Physics, California Institute of Technology, Pasadena, California 91125, USA","Materials Science and Engineering Department and Electrical and Computer Engineering Department, Boise State University, Boise, Idaho 83725, USA","Boise State University,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Applied Physics, California Institute of Technology, Pasadena, California 91125, USA","institution_ids":["https://openalex.org/I122411786"]},{"raw_affiliation_string":"Materials Science and Engineering Department and Electrical and Computer Engineering Department, Boise State University, Boise, Idaho 83725, USA","institution_ids":["https://openalex.org/I120156002"]},{"raw_affiliation_string":"Boise State University,","institution_ids":["https://openalex.org/I120156002"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.6509,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.66286022,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"82","issue":"4","first_page":"046307","last_page":"046307"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.4424000084400177,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.4424000084400177,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11379","display_name":"Rheology and Fluid Dynamics Studies","score":0.14149999618530273,"subfield":{"id":"https://openalex.org/subfields/1507","display_name":"Fluid Flow and Transfer Processes"},"field":{"id":"https://openalex.org/fields/15","display_name":"Chemical Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11582","display_name":"Nanopore and Nanochannel Transport Studies","score":0.07119999825954437,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dna-nanotubes","display_name":"DNA nanotubes","score":0.984000027179718},{"id":"https://openalex.org/keywords/chain-scission","display_name":"chain scission","score":0.8370000123977661},{"id":"https://openalex.org/keywords/extensional-flow","display_name":"extensional flow","score":0.9879999756813049},{"id":"https://openalex.org/keywords/laminar-flow","display_name":"laminar flow","score":0.9660000205039978},{"id":"https://openalex.org/keywords/semiflexible-polymers","display_name":"semiflexible polymers","score":0.8629999756813049},{"id":"https://openalex.org/keywords/dna-overstretching","display_name":"DNA overstretching","score":0.7229999899864197},{"id":"https://openalex.org/keywords/length-distribution","display_name":"length distribution","score":0.47600001096725464},{"id":"https://openalex.org/keywords/polymer-fragmentation","display_name":"polymer fragmentation","score":0.4959999918937683},{"id":"https://openalex.org/keywords/hydrodynamic-flow","display_name":"hydrodynamic flow","score":0.4050000011920929},{"id":"https://openalex.org/keywords/single-molecule-fluorescence","display_name":"single-molecule fluorescence","score":0.6790000200271606}],"concepts":[{"id":"https://openalex.org/C76563973","wikidata":"https://www.wikidata.org/wiki/Q189452","display_name":"Laminar flow","level":2,"score":0.737916886806488},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.6109404563903809},{"id":"https://openalex.org/C3044715","wikidata":"https://www.wikidata.org/wiki/Q3952437","display_name":"Bond cleavage","level":3,"score":0.5981374979019165},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.5592853426933289},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5433031916618347},{"id":"https://openalex.org/C207921521","wikidata":"https://www.wikidata.org/wiki/Q902120","display_name":"Polymer physics","level":3,"score":0.49729612469673157},{"id":"https://openalex.org/C159467904","wikidata":"https://www.wikidata.org/wiki/Q2001702","display_name":"Chemical physics","level":1,"score":0.394034743309021},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.36009758710861206},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3104858994483948},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.30316296219825745},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.19859501719474792},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.18208539485931396},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008856","descriptor_name":"Microscopy, Fluorescence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013314","descriptor_name":"Stress, Mechanical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016011","descriptor_name":"Normal Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020029","descriptor_name":"Base Pairing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D043942","descriptor_name":"Nanotubes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D046210","descriptor_name":"Microfluidic Analytical Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057446","descriptor_name":"Hydrodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1103/physreve.82.046307","doi":"https://doi.org/10.1103/physreve.82.046307","is_oa":false,"landing_page_url":"https://doi.org/10.1103/physreve.82.046307","pdf_url":null,"source":{"id":"https://openalex.org/S35412551","display_name":"Physical Review E","issn_l":"1539-3755","issn":["1539-3755","1550-2376"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","vabb-shw"],"host_organization":"https://openalex.org/P4310320261","host_organization_name":"American Physical Society","host_organization_lineage":["https://openalex.org/P4310320261"],"host_organization_lineage_names":["American Physical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physical Review E","raw_type":"journal-article"},{"id":"pmid:21230390","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21230390","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physical review. E, Statistical, nonlinear, and soft matter physics","raw_type":"Journal Article"},{"id":"pmh:oai:authors.library.caltech.edu:20727","doi":null,"is_oa":false,"landing_page_url":"https://resolver.caltech.edu/CaltechAUTHORS:20101109-091900905","pdf_url":null,"source":{"id":"https://openalex.org/S4306402161","display_name":"CaltechAUTHORS (California Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I122411786","host_organization_name":"California Institute of Technology","host_organization_lineage":["https://openalex.org/I122411786"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:scholarworks.boisestate.edu:electrical_facpubs-1091","doi":null,"is_oa":false,"landing_page_url":"https://scholarworks.boisestate.edu/electrical_facpubs/91","pdf_url":null,"source":{"id":"https://openalex.org/S4377196366","display_name":"Scholar Works  (Boise State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I120156002","host_organization_name":"Boise State University","host_organization_lineage":["https://openalex.org/I120156002"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Electrical and Computer Engineering Faculty Publications and Presentations","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1917741812","display_name":"NIRT:  Active Nanostructures for Nucleic Directed synthesis of Organic Functional Polymers","funder_award_id":"0608889","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G5482536919","display_name":"Nano: Collaborative Research: EMT: Toward Universal Bottom-Up Nanofabrication with DNA","funder_award_id":"0622254","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G6277356759","display_name":"Coarse-Graining DNA Energy Landscapes for the Analysis of Hybridization Kinetics","funder_award_id":"0506468","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320306101","display_name":"National Aeronautics and Space Administration","ror":"https://ror.org/027ka1x80"},{"id":"https://openalex.org/F4320309398","display_name":"California Institute of Technology","ror":"https://ror.org/05dxps055"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W1491935735","https://openalex.org/W1567090568","https://openalex.org/W1964441323","https://openalex.org/W1967332679","https://openalex.org/W1972859231","https://openalex.org/W1974900622","https://openalex.org/W1982162136","https://openalex.org/W1984962160","https://openalex.org/W1986329196","https://openalex.org/W2007619565","https://openalex.org/W2019733001","https://openalex.org/W2026908430","https://openalex.org/W2035333356","https://openalex.org/W2039216964","https://openalex.org/W2047961001","https://openalex.org/W2049974519","https://openalex.org/W2050207511","https://openalex.org/W2057949435","https://openalex.org/W2062802768","https://openalex.org/W2068334126","https://openalex.org/W2071311642","https://openalex.org/W2075906910","https://openalex.org/W2077830471","https://openalex.org/W2081407528","https://openalex.org/W2093484907","https://openalex.org/W2096887947","https://openalex.org/W2098818518","https://openalex.org/W2099414535","https://openalex.org/W2110758176","https://openalex.org/W2115447343","https://openalex.org/W2117552063","https://openalex.org/W2122742537","https://openalex.org/W2129186944","https://openalex.org/W2151023888","https://openalex.org/W2151086927","https://openalex.org/W2162010421","https://openalex.org/W2164975907","https://openalex.org/W2501705803"],"related_works":["https://openalex.org/W2018046145","https://openalex.org/W1984995295","https://openalex.org/W1980107517","https://openalex.org/W2039170384","https://openalex.org/W2059083911","https://openalex.org/W2065285613","https://openalex.org/W7131912879","https://openalex.org/W2896949877","https://openalex.org/W2116105460","https://openalex.org/W2151023888"],"abstract_inverted_index":{"The":[0,42,60,129],"length":[1,62],"distributions":[2],"of":[3,35,38,64],"polymer":[4,20],"fragments":[5,131],"subjected":[6],"to":[7,31,87,113],"an":[8],"elongational-flow-induced":[9],"scission":[10,34,149],"are":[11,144],"profoundly":[12],"affected":[13],"by":[14,73],"the":[15,19,75,83,98,109,124,138,148],"fluid":[16],"flow":[17,28,81],"and":[18,57,82,141],"bond":[21,55],"strengths.":[22],"In":[23],"this":[24],"paper,":[25],"laminar":[26],"elongational":[27,80],"was":[29,68],"used":[30],"induce":[32],"chain":[33],"a":[36,47,115],"series":[37],"circumference-programmed":[39],"DNA":[40,43,66,90,105,116,121,127],"nanotubes.":[41],"nanotubes":[44,67],"served":[45],"as":[46],"model":[48,94],"system":[49],"for":[50],"semiflexible":[51],"polymers":[52],"with":[53,134,147],"tunable":[54],"strength":[56],"cross-sectional":[58],"geometry.":[59],"expected":[61],"distribution":[63],"fragmented":[65],"calculated":[69],"from":[70,104],"first":[71],"principles":[72],"modeling":[74],"interplay":[76],"between":[77],"continuum":[78],"hydrodynamic":[79],"molecular":[84],"forces":[85],"required":[86,112],"overstretch":[88],"multiple":[89],"double":[91],"helices.":[92],"Our":[93],"has":[95],"no-free":[96],"parameters;":[97],"only":[99],"inferred":[100],"parameter":[101],"is":[102],"obtained":[103],"mechanics":[106],"literature,":[107],"namely,":[108],"critical":[110],"tension":[111],"break":[114],"duplex":[117],"into":[118],"two":[119],"single-stranded":[120],"strands":[122],"via":[123],"overstretching":[125],"B-S":[126],"transition.":[128],"nanotube":[130],"were":[132],"assayed":[133],"fluorescence":[135],"microscopy":[136],"at":[137],"single-molecule":[139],"level":[140],"their":[142],"lengths":[143],"in":[145],"agreement":[146],"theory.":[150]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}