{"id":"https://openalex.org/W2082066355","doi":"https://doi.org/10.1007/s102860200005","title":"Local sympathetic function in human skeletal muscle and adipose tissue assessed by microdialysis","display_name":"Local sympathetic function in human skeletal muscle and adipose tissue assessed by microdialysis","publication_year":2002,"publication_date":"2002-02-01","ids":{"openalex":"https://openalex.org/W2082066355","doi":"https://doi.org/10.1007/s102860200005","mag":"2082066355","pmid":"https://pubmed.ncbi.nlm.nih.gov/12102443"},"language":"en","primary_location":{"id":"doi:10.1007/s102860200005","doi":"https://doi.org/10.1007/s102860200005","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s102860200005","pdf_url":null,"source":{"id":"https://openalex.org/S134483451","display_name":"Clinical Autonomic Research","issn_l":"0959-9851","issn":["0959-9851","1619-1560"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Autonomic Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062076953","display_name":"SIMON R. BRUCE","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Simon Bruce","raw_affiliation_strings":["NINDS, NIH, Bethesda, Maryland 20892-1620, USA. sbruce@erols.com","NINDS, NIH, Bethesda, Maryland 20892-1620, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NINDS, NIH, Bethesda, Maryland 20892-1620, USA. sbruce@erols.com","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210110767"]},{"raw_affiliation_string":"NINDS, NIH, Bethesda, Maryland 20892-1620, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210110767"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011314920","display_name":"Cees J. Tack","orcid":"https://orcid.org/0000-0003-0322-1653","observed_orcids":["https://orcid.org/0000-0003-0322-1653"]},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Cees Tack","raw_affiliation_strings":["Department of Internal Medicine, University of Nijmegen, The Netherlands, NL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, University of Nijmegen, The Netherlands, NL","institution_ids":["https://openalex.org/I145872427"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111565681","display_name":"Jigisha Patel","orcid":"https://orcid.org/0000-0002-4017-9055","observed_orcids":["https://orcid.org/0000-0002-4017-9055"]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jigisha Patel","raw_affiliation_strings":["University College, London, UK, , GB"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University College, London, UK, , GB","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068457694","display_name":"Karel Pac\u00e1k","orcid":"https://orcid.org/0000-0002-3541-3767","observed_orcids":["https://orcid.org/0000-0002-3541-3767"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Karel Pacak","raw_affiliation_strings":["Building 10, Room 6N252, NINDS, NIH, 10 Center Drive, MSC\u20131620, Bethesda, Maryland 20892\u20131620, USA, Tel.: +1-6 09/2 52-56 04, +1-3 01/4 96-21 03, Fax: +1-6 09/2 52-67 01, +1-3 01/4 02-01 80, E-Mail: sbruce@erols.com, goldsteind@ninds.nih.gov, , US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Building 10, Room 6N252, NINDS, NIH, 10 Center Drive, MSC\u20131620, Bethesda, Maryland 20892\u20131620, USA, Tel.: +1-6 09/2 52-56 04, +1-3 01/4 96-21 03, Fax: +1-6 09/2 52-67 01, +1-3 01/4 02-01 80, E-Mail: sbruce@erols.com, goldsteind@ninds.nih.gov, , US","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210110767"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050003203","display_name":"David S. Goldstein","orcid":"https://orcid.org/0000-0002-5709-9940","observed_orcids":["https://orcid.org/0000-0002-5709-9940"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David S. Goldstein","raw_affiliation_strings":["Clinical Neurocardiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Neurocardiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health,","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210110767"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4790,"currency":"USD","value_usd":4790},"apc_paid":null,"fwci":0.8075,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.72060572,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"12","issue":"1","first_page":"13","last_page":"19"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.33809998631477356,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.33809998631477356,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11950","display_name":"Cardiovascular Syncope and Autonomic Disorders","score":0.11320000141859055,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.09690000116825104,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/skeletal-muscle","display_name":"skeletal muscle","score":0.7680000066757202},{"id":"https://openalex.org/keywords/adipose-tissue","display_name":"adipose tissue","score":0.9639999866485596},{"id":"https://openalex.org/keywords/norepinephrine","display_name":"norepinephrine","score":0.925000011920929},{"id":"https://openalex.org/keywords/dihydroxyphenylglycol","display_name":"dihydroxyphenylglycol","score":0.9919999837875366},{"id":"https://openalex.org/keywords/catechol","display_name":"catechol","score":0.8349999785423279},{"id":"https://openalex.org/keywords/microdialysis","display_name":"microdialysis","score":0.890999972820282},{"id":"https://openalex.org/keywords/orthostasis","display_name":"orthostasis","score":0.8360000252723694},{"id":"https://openalex.org/keywords/trimethaphan","display_name":"trimethaphan","score":0.890999972820282},{"id":"https://openalex.org/keywords/sympathetic-nerve-activity","display_name":"sympathetic activity","score":0.7580000162124634},{"id":"https://openalex.org/keywords/quadriceps","display_name":"quadriceps","score":0.6100000143051147},{"id":"https://openalex.org/keywords/subcutaneous-adipose-tissue","display_name":"subcutaneous adipose tissue","score":0.8740000128746033},{"id":"https://openalex.org/keywords/sympathetic-innervation","display_name":"sympathetic innervation","score":0.3580000102519989}],"concepts":[{"id":"https://openalex.org/C50156730","wikidata":"https://www.wikidata.org/wiki/Q3856966","display_name":"Microdialysis","level":3,"score":0.900383710861206},{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.7089628577232361},{"id":"https://openalex.org/C2779959927","wikidata":"https://www.wikidata.org/wiki/Q1048687","display_name":"Skeletal muscle","level":2,"score":0.7001953721046448},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6115170121192932},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.607850968837738},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5948119163513184},{"id":"https://openalex.org/C2776533406","wikidata":"https://www.wikidata.org/wiki/Q187215","display_name":"Sympathetic nervous system","level":3,"score":0.5658240914344788},{"id":"https://openalex.org/C2778514916","wikidata":"https://www.wikidata.org/wiki/Q186242","display_name":"Norepinephrine","level":3,"score":0.5518298745155334},{"id":"https://openalex.org/C2775894120","wikidata":"https://www.wikidata.org/wiki/Q271663","display_name":"Catecholamine","level":2,"score":0.5353918671607971},{"id":"https://openalex.org/C125567185","wikidata":"https://www.wikidata.org/wiki/Q3267428","display_name":"Supine position","level":2,"score":0.5200942754745483},{"id":"https://openalex.org/C140985366","wikidata":"https://www.wikidata.org/wiki/Q898489","display_name":"Lipolysis","level":3,"score":0.44408535957336426},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.32986652851104736},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.15394333004951477},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.10255447030067444}],"mesh":[{"descriptor_ui":"D000273","descriptor_name":"Adipose Tissue","qualifier_ui":"Q000294","qualifier_name":"innervation","is_major_topic":false},{"descriptor_ui":"D000273","descriptor_name":"Adipose Tissue","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002138","descriptor_name":"Calibration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002395","descriptor_name":"Catecholamines","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D004244","descriptor_name":"Dizziness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005089","descriptor_name":"Exocytosis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005730","descriptor_name":"Ganglionic Blockers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008734","descriptor_name":"Methoxyhydroxyphenylglycol","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D008734","descriptor_name":"Methoxyhydroxyphenylglycol","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009638","descriptor_name":"Norepinephrine","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D013564","descriptor_name":"Sympathetic Nervous System","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D014294","descriptor_name":"Trimethaphan","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017551","descriptor_name":"Microdialysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000294","qualifier_name":"innervation","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1007/s102860200005","doi":"https://doi.org/10.1007/s102860200005","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s102860200005","pdf_url":null,"source":{"id":"https://openalex.org/S134483451","display_name":"Clinical Autonomic Research","issn_l":"0959-9851","issn":["0959-9851","1619-1560"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Autonomic Research","raw_type":"journal-article"},{"id":"pmid:12102443","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12102443","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical autonomic research : official journal of the Clinical Autonomic Research Society","raw_type":"Clinical Trial"},{"id":"pmh:oai:repository.ubn.ru.nl:2066/186609","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/2066/186609","pdf_url":null,"source":{"id":"https://openalex.org/S4306401067","display_name":"Radboud Repository (Radboud University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I145872427","host_organization_name":"Radboud University Nijmegen","host_organization_lineage":["https://openalex.org/I145872427"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article / Letter to editor"},{"id":"pmh:ru:oai:repository.ubn.ru.nl:2066/186609","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/2066/186609","pdf_url":null,"source":{"id":"https://openalex.org/S4306401067","display_name":"Radboud Repository (Radboud University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I145872427","host_organization_name":"Radboud University Nijmegen","host_organization_lineage":["https://openalex.org/I145872427"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Clinical Autonomic Research, 12, 13 - 9","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9763000011444092}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W179628100","https://openalex.org/W1588195558","https://openalex.org/W1886353442","https://openalex.org/W1907243647","https://openalex.org/W1964189568","https://openalex.org/W1969081729","https://openalex.org/W1975991139","https://openalex.org/W1984981926","https://openalex.org/W1989692828","https://openalex.org/W1990708146","https://openalex.org/W2010252483","https://openalex.org/W2016313631","https://openalex.org/W2020598149","https://openalex.org/W2022451129","https://openalex.org/W2025481166","https://openalex.org/W2026489163","https://openalex.org/W2034743887","https://openalex.org/W2038042000","https://openalex.org/W2040345125","https://openalex.org/W2047474099","https://openalex.org/W2047631720","https://openalex.org/W2049824663","https://openalex.org/W2064579956","https://openalex.org/W2082595450","https://openalex.org/W2087873471","https://openalex.org/W2091005984","https://openalex.org/W2094591619","https://openalex.org/W2150759625","https://openalex.org/W2268807319","https://openalex.org/W2279182902","https://openalex.org/W2323218437","https://openalex.org/W2423206418","https://openalex.org/W2430566197","https://openalex.org/W2564571319"],"related_works":["https://openalex.org/W2430566197","https://openalex.org/W2047060845","https://openalex.org/W2085801496","https://openalex.org/W1548914024","https://openalex.org/W2116851381","https://openalex.org/W2422405004","https://openalex.org/W2016489821","https://openalex.org/W2085722628","https://openalex.org/W227168154","https://openalex.org/W4235458151"],"abstract_inverted_index":null,"counts_by_year":[{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}