{"id":"https://openalex.org/W2081676869","doi":"https://doi.org/10.1016/0008-8749(81)90028-9","title":"Macrophages as effectors of T suppression: T-lymphocyte-dependent macrophage-mediated suppression of mitogen-induced blastogenesis in the rat","display_name":"Macrophages as effectors of T suppression: T-lymphocyte-dependent macrophage-mediated suppression of mitogen-induced blastogenesis in the rat","publication_year":1981,"publication_date":"1981-09-01","ids":{"openalex":"https://openalex.org/W2081676869","doi":"https://doi.org/10.1016/0008-8749(81)90028-9","mag":"2081676869","pmid":"https://pubmed.ncbi.nlm.nih.gov/6974049"},"language":"en","primary_location":{"id":"doi:10.1016/0008-8749(81)90028-9","doi":"https://doi.org/10.1016/0008-8749(81)90028-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0008-8749(81)90028-9","pdf_url":null,"source":{"id":"https://openalex.org/S193466101","display_name":"Cellular Immunology","issn_l":"0008-8749","issn":["0008-8749","1090-2163"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular Immunology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017272011","display_name":"Patrick G. Holt","orcid":"https://orcid.org/0000-0003-1193-0935","observed_orcids":["https://orcid.org/0000-0003-1193-0935"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Patrick G. Holt","raw_affiliation_strings":["Clinical Immunology Research Unit, Princess Margaret Children's Medical Research Foundation, Princess Margaret Hospital, Subiaco, 6008, Western Australia, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Immunology Research Unit, Princess Margaret Children's Medical Research Foundation, Princess Margaret Hospital, Subiaco, 6008, Western Australia, Australia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014028544","display_name":"Louise A. Warner","orcid":"https://orcid.org/0000-0001-9161-3272","observed_orcids":["https://orcid.org/0000-0001-9161-3272"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Louise A. Warner","raw_affiliation_strings":["Clinical Immunology Research Unit, Princess Margaret Children's Medical Research Foundation, Princess Margaret Hospital, Subiaco, 6008, Western Australia, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Immunology Research Unit, Princess Margaret Children's Medical Research Foundation, Princess Margaret Hospital, Subiaco, 6008, Western Australia, Australia","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5032926963","display_name":"Graham Mayrhofer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Graham Mayrhofer","raw_affiliation_strings":["Clinical Immunology Research Unit, Princess Margaret Children's Medical Research Foundation, Princess Margaret Hospital, Subiaco, 6008, Western Australia, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Immunology Research Unit, Princess Margaret Children's Medical Research Foundation, Princess Margaret Hospital, Subiaco, 6008, Western Australia, Australia","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3550,"currency":"USD","value_usd":3550},"apc_paid":null,"fwci":1.7662,"has_fulltext":false,"cited_by_count":30,"citation_normalized_percentile":{"value":0.85089218,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"63","issue":"1","first_page":"57","last_page":"70"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9624000191688538,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9624000191688538,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11313","display_name":"Immune cells in cancer","score":0.032099999487400055,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14072","display_name":"Immunotoxicology and immune responses","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/macrophages","display_name":"macrophages","score":0.8069999814033508},{"id":"https://openalex.org/keywords/t-cell-suppression","display_name":"T cell suppression","score":0.593999981880188},{"id":"https://openalex.org/keywords/regulatory-t-cells","display_name":"regulatory T cells","score":0.7829999923706055},{"id":"https://openalex.org/keywords/mitogen-induced-lymphocyte-proliferation","display_name":"mitogen-induced lymphocyte proliferation","score":0.8360000252723694},{"id":"https://openalex.org/keywords/peritoneal-macrophages","display_name":"peritoneal macrophages","score":0.8870000243186951},{"id":"https://openalex.org/keywords/cytostatic-effect","display_name":"cytostatic activity","score":0.5989999771118164},{"id":"https://openalex.org/keywords/neonatal-period","display_name":"neonatal period","score":0.5080000162124634},{"id":"https://openalex.org/keywords/splenocytes","display_name":"splenocytes","score":0.7260000109672546},{"id":"https://openalex.org/keywords/primary-immune-response","display_name":"primary immune response","score":0.7670000195503235},{"id":"https://openalex.org/keywords/antithymocyte-serum","display_name":"antithymocyte serum","score":0.8169999718666077},{"id":"https://openalex.org/keywords/cyclophosphamide","display_name":"cyclophosphamide","score":0.8579999804496765}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8117130994796753},{"id":"https://openalex.org/C189976730","wikidata":"https://www.wikidata.org/wiki/Q3493700","display_name":"Splenocyte","level":3,"score":0.6215720772743225},{"id":"https://openalex.org/C2777761686","wikidata":"https://www.wikidata.org/wiki/Q715347","display_name":"Lymphocyte","level":2,"score":0.5777138471603394},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5764515995979309},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5664017200469971},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.5239957571029663},{"id":"https://openalex.org/C2779244956","wikidata":"https://www.wikidata.org/wiki/Q184204","display_name":"Macrophage","level":3,"score":0.5215209126472473},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.5027954578399658},{"id":"https://openalex.org/C2778954852","wikidata":"https://www.wikidata.org/wiki/Q7799635","display_name":"Thymocyte","level":4,"score":0.4837925136089325},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.47589147090911865},{"id":"https://openalex.org/C2992881475","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T lymphocyte","level":3,"score":0.45465022325515747},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.40833550691604614},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.40581661462783813},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.392853319644928},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.10849115252494812},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.07999017834663391},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000961","descriptor_name":"Antilymphocyte Serum","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002469","descriptor_name":"Cell Separation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003520","descriptor_name":"Cyclophosphamide","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007165","descriptor_name":"Immunosuppression Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008213","descriptor_name":"Lymphocyte Activation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008934","descriptor_name":"Mitogens","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D011920","descriptor_name":"Rats, Inbred WF","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013154","descriptor_name":"Spleen","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D013897","descriptor_name":"Thoracic Duct","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013934","descriptor_name":"Thymectomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0008-8749(81)90028-9","doi":"https://doi.org/10.1016/0008-8749(81)90028-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0008-8749(81)90028-9","pdf_url":null,"source":{"id":"https://openalex.org/S193466101","display_name":"Cellular Immunology","issn_l":"0008-8749","issn":["0008-8749","1090-2163"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular Immunology","raw_type":"journal-article"},{"id":"pmid:6974049","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6974049","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular immunology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8371999859809875}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W144541305","https://openalex.org/W149337431","https://openalex.org/W960017613","https://openalex.org/W1216619358","https://openalex.org/W1484285187","https://openalex.org/W1496795923","https://openalex.org/W1507981583","https://openalex.org/W1509943896","https://openalex.org/W1510894504","https://openalex.org/W1553654116","https://openalex.org/W1583379470","https://openalex.org/W1909717545","https://openalex.org/W1914013696","https://openalex.org/W1971394992","https://openalex.org/W1974204636","https://openalex.org/W1976200405","https://openalex.org/W2027771189","https://openalex.org/W2043555825","https://openalex.org/W2052124211","https://openalex.org/W2057668259","https://openalex.org/W2058833242","https://openalex.org/W2064275362","https://openalex.org/W2064303564","https://openalex.org/W2068414160","https://openalex.org/W2087585110","https://openalex.org/W2095299399","https://openalex.org/W2102481708","https://openalex.org/W2157306327","https://openalex.org/W2402274966","https://openalex.org/W2414096341","https://openalex.org/W4313310101"],"related_works":["https://openalex.org/W144541305","https://openalex.org/W2029216307","https://openalex.org/W1969327070","https://openalex.org/W1591122982","https://openalex.org/W2160428464","https://openalex.org/W1978295182","https://openalex.org/W1847780242","https://openalex.org/W1771987985","https://openalex.org/W1989188561","https://openalex.org/W1986204595"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}