{"id":"https://openalex.org/W2081080164","doi":"https://doi.org/10.1016/j.nucmedbio.2010.02.008","title":"Synthesis and in vivo evaluation of the putative breast cancer resistance protein inhibitor [11C]methyl 4-((4-(2-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl)phenyl)amino-carbonyl)-2-(quinoline-2-carbonylamino)benzoate","display_name":"Synthesis and in vivo evaluation of the putative breast cancer resistance protein inhibitor [11C]methyl 4-((4-(2-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl)phenyl)amino-carbonyl)-2-(quinoline-2-carbonylamino)benzoate","publication_year":2010,"publication_date":"2010-04-12","ids":{"openalex":"https://openalex.org/W2081080164","doi":"https://doi.org/10.1016/j.nucmedbio.2010.02.008","mag":"2081080164","pmid":"https://pubmed.ncbi.nlm.nih.gov/20610168","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3690702"},"language":"en","primary_location":{"id":"doi:10.1016/j.nucmedbio.2010.02.008","doi":"https://doi.org/10.1016/j.nucmedbio.2010.02.008","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.nucmedbio.2010.02.008","pdf_url":null,"source":{"id":"https://openalex.org/S24354371","display_name":"Nuclear Medicine and Biology","issn_l":"0969-8051","issn":["0969-8051","1872-9614"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nuclear Medicine and Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/articles/PMC3690702","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084767379","display_name":"Severin Mairinger","orcid":"https://orcid.org/0000-0001-5094-9351","observed_orcids":["https://orcid.org/0000-0001-5094-9351"]},"institutions":[{"id":"https://openalex.org/I129774422","display_name":"University of Vienna","ror":"https://ror.org/03prydq77","country_code":"AT","type":"education","lineage":["https://openalex.org/I129774422"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Severin Mairinger","raw_affiliation_strings":["Department of Medicinal Chemistry, University of Vienna, 1090 Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicinal Chemistry, University of Vienna, 1090 Vienna, Austria","institution_ids":["https://openalex.org/I129774422"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004953156","display_name":"Oliver Langer","orcid":"https://orcid.org/0000-0002-4048-5781","observed_orcids":["https://orcid.org/0000-0002-4048-5781"]},"institutions":[{"id":"https://openalex.org/I132118926","display_name":"AIT Austrian Institute of Technology GmbH","ror":"https://ror.org/04knbh022","country_code":"AT","type":"facility","lineage":["https://openalex.org/I132118926"]},{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":true,"raw_author_name":"Oliver Langer","raw_affiliation_strings":["Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria","Molecular Medicine, AIT Austrian Institute of Technology GmbH, 2444 Seibersdorf, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]},{"raw_affiliation_string":"Molecular Medicine, AIT Austrian Institute of Technology GmbH, 2444 Seibersdorf, Austria","institution_ids":["https://openalex.org/I132118926"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077798421","display_name":"Claudia Kuntner","orcid":"https://orcid.org/0000-0002-5988-1434","observed_orcids":["https://orcid.org/0000-0002-5988-1434"]},"institutions":[{"id":"https://openalex.org/I132118926","display_name":"AIT Austrian Institute of Technology GmbH","ror":"https://ror.org/04knbh022","country_code":"AT","type":"facility","lineage":["https://openalex.org/I132118926"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Claudia Kuntner","raw_affiliation_strings":["Molecular Medicine, AIT Austrian Institute of Technology GmbH, 2444 Seibersdorf, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular Medicine, AIT Austrian Institute of Technology GmbH, 2444 Seibersdorf, Austria","institution_ids":["https://openalex.org/I132118926"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000309304","display_name":"Thomas Wanek","orcid":"https://orcid.org/0000-0002-0404-4452","observed_orcids":["https://orcid.org/0000-0002-0404-4452"]},"institutions":[{"id":"https://openalex.org/I132118926","display_name":"AIT Austrian Institute of Technology GmbH","ror":"https://ror.org/04knbh022","country_code":"AT","type":"facility","lineage":["https://openalex.org/I132118926"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Thomas Wanek","raw_affiliation_strings":["Molecular Medicine, AIT Austrian Institute of Technology GmbH, 2444 Seibersdorf, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular Medicine, AIT Austrian Institute of Technology GmbH, 2444 Seibersdorf, Austria","institution_ids":["https://openalex.org/I132118926"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051853544","display_name":"Jens P. Bankstahl","orcid":"https://orcid.org/0000-0003-4735-4490","observed_orcids":["https://orcid.org/0000-0003-4735-4490"]},"institutions":[{"id":"https://openalex.org/I189991","display_name":"University of Veterinary Medicine Hannover, Foundation","ror":"https://ror.org/015qjqf64","country_code":"DE","type":"education","lineage":["https://openalex.org/I189991"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Jens P. Bankstahl","raw_affiliation_strings":["Department of Pharmacology, Toxicology & Pharmacy, University of Veterinary Medicine Hanover, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, Toxicology & Pharmacy, University of Veterinary Medicine Hanover, Germany","institution_ids":["https://openalex.org/I189991"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041304153","display_name":"Marion Bankstahl","orcid":"https://orcid.org/0000-0002-5775-188X","observed_orcids":["https://orcid.org/0000-0002-5775-188X"]},"institutions":[{"id":"https://openalex.org/I189991","display_name":"University of Veterinary Medicine Hannover, Foundation","ror":"https://ror.org/015qjqf64","country_code":"DE","type":"education","lineage":["https://openalex.org/I189991"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Marion Bankstahl","raw_affiliation_strings":["Department of Pharmacology, Toxicology & Pharmacy, University of Veterinary Medicine Hanover, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, Toxicology & Pharmacy, University of Veterinary Medicine Hanover, Germany","institution_ids":["https://openalex.org/I189991"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087793408","display_name":"Johann Stanek","orcid":"https://orcid.org/0000-0002-7269-8781","observed_orcids":["https://orcid.org/0000-0002-7269-8781"]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Johann Stanek","raw_affiliation_strings":["Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057370242","display_name":"Bernd D\u00f6rner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129774422","display_name":"University of Vienna","ror":"https://ror.org/03prydq77","country_code":"AT","type":"education","lineage":["https://openalex.org/I129774422"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Bernd D\u00f6rner","raw_affiliation_strings":["Department of Medicinal Chemistry, University of Vienna, 1090 Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicinal Chemistry, University of Vienna, 1090 Vienna, Austria","institution_ids":["https://openalex.org/I129774422"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Florian Bauer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129774422","display_name":"University of Vienna","ror":"https://ror.org/03prydq77","country_code":"AT","type":"education","lineage":["https://openalex.org/I129774422"]},{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Florian Bauer","raw_affiliation_strings":["Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria","Department of Medicinal Chemistry, University of Vienna, 1090 Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]},{"raw_affiliation_string":"Department of Medicinal Chemistry, University of Vienna, 1090 Vienna, Austria","institution_ids":["https://openalex.org/I129774422"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103164888","display_name":"Christoph Baumgartner","orcid":"https://orcid.org/0000-0003-4766-988X","observed_orcids":["https://orcid.org/0000-0003-4766-988X"]},"institutions":[{"id":"https://openalex.org/I4210089076","display_name":"Klinik Hietzing","ror":"https://ror.org/00621wh10","country_code":"AT","type":"healthcare","lineage":["https://openalex.org/I4210089076","https://openalex.org/I4210117134"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Christoph Baumgartner","raw_affiliation_strings":["2nd Neurological Department, General Hospital Hietzing with Neurological Center Rosenh\u00fcgel, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2nd Neurological Department, General Hospital Hietzing with Neurological Center Rosenh\u00fcgel, Vienna, Austria","institution_ids":["https://openalex.org/I4210089076"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010235451","display_name":"Wolfgang L\u00f6scher","orcid":"https://orcid.org/0000-0002-9648-8973","observed_orcids":["https://orcid.org/0000-0002-9648-8973"]},"institutions":[{"id":"https://openalex.org/I189991","display_name":"University of Veterinary Medicine Hannover, Foundation","ror":"https://ror.org/015qjqf64","country_code":"DE","type":"education","lineage":["https://openalex.org/I189991"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Wolfgang L\u00f6scher","raw_affiliation_strings":["Department of Pharmacology, Toxicology & Pharmacy, University of Veterinary Medicine Hanover, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, Toxicology & Pharmacy, University of Veterinary Medicine Hanover, Germany","institution_ids":["https://openalex.org/I189991"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056834055","display_name":"Thomas Erker","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129774422","display_name":"University of Vienna","ror":"https://ror.org/03prydq77","country_code":"AT","type":"education","lineage":["https://openalex.org/I129774422"]}],"countries":["AT"],"is_corresponding":true,"raw_author_name":"Thomas Erker","raw_affiliation_strings":["Department of Medicinal Chemistry, University of Vienna, 1090 Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicinal Chemistry, University of Vienna, 1090 Vienna, Austria","institution_ids":["https://openalex.org/I129774422"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076180813","display_name":"Markus M\u00fcller","orcid":"https://orcid.org/0000-0001-9953-9759","observed_orcids":["https://orcid.org/0000-0001-9953-9759"]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Markus M\u00fcller","raw_affiliation_strings":["Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5004953156","https://openalex.org/A5056834055"],"corresponding_institution_ids":["https://openalex.org/I129774422","https://openalex.org/I132118926","https://openalex.org/I76134821"],"apc_list":{"value":3740,"currency":"USD","value_usd":3740},"apc_paid":null,"fwci":0.9823,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.76784044,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"37","issue":"5","first_page":"637","last_page":"644"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10570","display_name":"Drug Transport and Resistance Mechanisms","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10570","display_name":"Drug Transport and Resistance Mechanisms","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11395","display_name":"Radiopharmaceutical Chemistry and Applications","score":0.005900000222027302,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/abcg2","display_name":"ABCG2","score":0.9599999785423279},{"id":"https://openalex.org/keywords/pet-radiotracer","display_name":"PET radiotracer","score":0.5379999876022339},{"id":"https://openalex.org/keywords/multidrug-efflux-transporter","display_name":"multidrug efflux transporter","score":0.6899999976158142},{"id":"https://openalex.org/keywords/blood-brain-barrier","display_name":"blood-brain barrier","score":0.9430000185966492},{"id":"https://openalex.org/keywords/p-glycoprotein","display_name":"P-glycoprotein","score":0.9369999766349792},{"id":"https://openalex.org/keywords/tariquidar","display_name":"tariquidar","score":0.7049999833106995},{"id":"https://openalex.org/keywords/radiosynthesis","display_name":"radiotracer synthesis","score":0.7319999933242798},{"id":"https://openalex.org/keywords/radiometabolites","display_name":"radiometabolites","score":0.6809999942779541},{"id":"https://openalex.org/keywords/brain-to-plasma-ratio","display_name":"brain-to-plasma ratio","score":0.6729999780654907}],"concepts":[{"id":"https://openalex.org/C512196","wikidata":"https://www.wikidata.org/wiki/Q4650095","display_name":"Abcg2","level":5,"score":0.8869080543518066},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.8289049863815308},{"id":"https://openalex.org/C2778707650","wikidata":"https://www.wikidata.org/wiki/Q412902","display_name":"P-glycoprotein","level":4,"score":0.6828941106796265},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6489812135696411},{"id":"https://openalex.org/C200082930","wikidata":"https://www.wikidata.org/wiki/Q22327148","display_name":"Efflux","level":2,"score":0.5744019746780396},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5117406845092773},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.4840211570262909},{"id":"https://openalex.org/C26291073","wikidata":"https://www.wikidata.org/wiki/Q310484","display_name":"Ex vivo","level":3,"score":0.4749971628189087},{"id":"https://openalex.org/C112705442","wikidata":"https://www.wikidata.org/wiki/Q323936","display_name":"Pharmacokinetics","level":2,"score":0.47367554903030396},{"id":"https://openalex.org/C2776678969","wikidata":"https://www.wikidata.org/wiki/Q28209167","display_name":"Organic anion-transporting polypeptide","level":4,"score":0.448991984128952},{"id":"https://openalex.org/C149011108","wikidata":"https://www.wikidata.org/wiki/Q652985","display_name":"Transporter","level":3,"score":0.44451650977134705},{"id":"https://openalex.org/C2775842073","wikidata":"https://www.wikidata.org/wiki/Q208376","display_name":"Positron emission tomography","level":2,"score":0.44096970558166504},{"id":"https://openalex.org/C2778402981","wikidata":"https://www.wikidata.org/wiki/Q221694","display_name":"Blood\u2013brain barrier","level":3,"score":0.4361925721168518},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.3613799512386322},{"id":"https://openalex.org/C44312359","wikidata":"https://www.wikidata.org/wiki/Q286958","display_name":"ATP-binding cassette transporter","level":4,"score":0.2978164553642273},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.28535932302474976},{"id":"https://openalex.org/C133936738","wikidata":"https://www.wikidata.org/wiki/Q643839","display_name":"Multiple drug resistance","level":3,"score":0.2440270185470581},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.228131502866745},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.18534278869628906},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.18245738744735718},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.11937683820724487},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.07659003138542175},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000070997","descriptor_name":"ATP Binding Cassette Transporter, Subfamily G, Member 2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001565","descriptor_name":"Benzoates","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":true},{"descriptor_ui":"D001565","descriptor_name":"Benzoates","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D001812","descriptor_name":"Blood-Brain Barrier","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001812","descriptor_name":"Blood-Brain Barrier","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004353","descriptor_name":"Drug Evaluation, Preclinical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004355","descriptor_name":"Drug Stability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011804","descriptor_name":"Quinolines","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":true},{"descriptor_ui":"D011804","descriptor_name":"Quinolines","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D011849","descriptor_name":"Radioactive Tracers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018528","descriptor_name":"ATP-Binding Cassette Transporters","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D018528","descriptor_name":"ATP-Binding Cassette Transporters","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018528","descriptor_name":"ATP-Binding Cassette Transporters","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020168","descriptor_name":"ATP Binding Cassette Transporter, Subfamily B, Member 1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D049268","descriptor_name":"Positron-Emission Tomography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055786","descriptor_name":"Gene Knockout Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.nucmedbio.2010.02.008","doi":"https://doi.org/10.1016/j.nucmedbio.2010.02.008","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.nucmedbio.2010.02.008","pdf_url":null,"source":{"id":"https://openalex.org/S24354371","display_name":"Nuclear Medicine and Biology","issn_l":"0969-8051","issn":["0969-8051","1872-9614"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nuclear Medicine and Biology","raw_type":"journal-article"},{"id":"pmid:20610168","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20610168","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nuclear medicine and biology","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:2684802","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3690702","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3690702","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3690702","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Nucl Med Biol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2684802","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3690702","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321181","display_name":"Austrian Science Fund","ror":"https://ror.org/013tf3c58"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W1546135534","https://openalex.org/W1886326176","https://openalex.org/W1968514574","https://openalex.org/W1971607633","https://openalex.org/W1985529531","https://openalex.org/W1989064705","https://openalex.org/W2021275669","https://openalex.org/W2029357552","https://openalex.org/W2044786521","https://openalex.org/W2052329451","https://openalex.org/W2062693496","https://openalex.org/W2064865731","https://openalex.org/W2068408065","https://openalex.org/W2072981607","https://openalex.org/W2079785947","https://openalex.org/W2083793124","https://openalex.org/W2084769078","https://openalex.org/W2116749841","https://openalex.org/W2119085762","https://openalex.org/W2129122317","https://openalex.org/W2148146955","https://openalex.org/W2152546397","https://openalex.org/W2153474045","https://openalex.org/W2160368116","https://openalex.org/W2166637794"],"related_works":["https://openalex.org/W1975209977","https://openalex.org/W1982875074","https://openalex.org/W2025743346","https://openalex.org/W2465296898","https://openalex.org/W1971607633","https://openalex.org/W1988248685","https://openalex.org/W7100094143","https://openalex.org/W1972496840","https://openalex.org/W7096735046","https://openalex.org/W2052142494"],"abstract_inverted_index":null,"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}